This issue of Neurologic Clinics offers a rounded view of the latest therapeutic advances for the most common neurologic disorders and contains the following articles: Management Controversy in Chronic Daily Headaches (Rahmadan); Neurostimulation in Headache Patients (Dafer); The Selection of Anti-epileptic Drugs for the Treatment of Epilepsy in Children and Adults (Asconape); Management of Status Epilepticus in Adults (Rabinstein); Management of Blood Pressure in Acute and Hemorrhagic Stroke (Schneck); Modern Management of Brainstem Cavernous Malformations (Duckworth); Endovascular Treatment of Intracranial Dural Arteriovenous Fistulas (Narayanan); Management of Motor Complications of Parkinson’s Disease (Espay); Therapeutic Challenges in Dystonias (Kartha); Management of Voltage Gated Potassium Channel Antibody Disorders (Merchut); Management of Critical Care Neuromyopathies (Chawla, Gruener); Approaches to Peripheral Nerve Disorders (Toussaint, Anderson); Management of Idiopathic Intracranial Hypertension (Digre, Spencer); Management of Low Grade Gliomas (Prabhu); Management of Acute, Recurrent, and Chronic Meningitdes in Adults (Venna); and Treatment Options for Adult Parasomnias (Attarian).