As your bridge from the basic sciences to the clinical sciences, this book introduces "disease" as disorders of body function. Pathophysiology of Disease focuses on 100 diseases commonly encountered in medical practice. Each chapter first describes the normal structure and function of a major organ or organ system, then turns attention to the pathology and disordered physiology, including the roles of genetics, immunology, and infection in pathogenesis. Underlying disease mechanisms are described, along with their systems and signs and the way those mechanisms themselves determine which treatments will be most effective.