Adaptation - Part 5 takes up in the aftermath of the showdown in Minneapolis. Houston is rocked by the chaos Ottavio wrought, Project Adaptation is threatened by the Board, yet housed within the pandemonium lies Master Penelope's unflappable plan. Von Braun and the crabman virus have been retrieved, but this only spells further trials for Ottavio as he battles against the interested factions. Ryan, torn between his desire for a life with Esther and the superhuman future he has been promised, must decide what he truly believes about humanity. Part five sees Ryan mature past his own desires, and finds Ottavio plunging further into the web of Marcus.