The recent dramatic increase in the incidence of Cryptococcus neoformans infections calls for an up–to–date look at the biology and pathogenesis of this fungus. The last monograph on this subject was written in 1956; since then much has been learned about this subject, and because of the AIDS epidemic, its medical importance is now significant. This major new book covers the biology and major clinical developments of C. neoformans infections, including theoretical as well as practical information (how to prepare reagents, for instance). This subject area has become a major concern facing infectious disease physicians in the era of AIDS and immunocompromised patients. Researchers and clinicians alike will find this new text to be an invaluable reference about this increasingly deadly fungal pathogen.