Intended for both medical students and academics in the fields of ophthalmology, neurology and oncology, this textbook serves to educate ophthalmologists, neurologists and oncologists on a disease process that is often difficult to diagnose, primary intraocular lymphoma (PIOL). To help readers recognize the malignancy, a presentation of common and less frequently occurring clinical manifestations of the disease is given. The book provides ophthalmologists the guidelines on current diagnostic and therapeutic modalities as well as the historical background of PIOL.