The book begins by describing how and why epigenesis came to replace the reigning model of biological origination, preformation - the theory that all organisms were preformed at the creation of the world. Contemporary with these developments, Kant used the figures of epigenesis and self-formation to illustrate his concepts of the origin of the categories, the possible success of practical reason, and the validity of aesthetic and teleological judgments. The author shows how Kant's figurative use of self-generation was turned into an indispensable determination by Fichte and his successors: philosophical knowledge can claim absolute certainty only if it can prove that it generates itself in logically accountable procedures.