This book examines the subject of fire prevention which has been of great significance and importance throughout man's history. This is because although laboratory scientists has learnt to use it every day for flaming, sterilization, decontamination, boiling, heating, incineration of wastes and other laboratory work, he has yet to learn how to control fire especially scientists in a tuberculosis (TB), human immune deficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) reference laboratory. If fire is not properly controlled in the TB/HIV/AIDS reference laboratory, fire can destroy both the scientist and the TB/HIV/AIDS reference laboratory. It is therefore imperative that the knowledge of control and prevention of fire outbreak in the TB/HIV/AIDS reference laboratory must be pursued.