This book is one of several devoted to publishing the archaeology of the large house now known as the "House of Serenos" (or more technically as B(uilding) 1 in Area 2.1) of Amheida, the ancient Roman city of Trimithis in the Dakhla Oasis of the Western Desert of Egypt, administratively today part of the New Valley Governorate. Amheida V published the analysis and catalogue of the pottery (published by ISAW, August 2020); Amheida VII will contain the analysis and catalogue of the small finds from B1; and a subsequent volume in the Amheida series will record and analyze the extensive paintings and decorations of B1. The present volume synthesizes the detailed archaeology information presented by the other Amheida volumes dedicated to the House of Serenos in a comprehensive study of the architectural and archaeological history of the house and the deposits located below it. A methodological chapter (Chapter 1) introduces the volume, explaining archaeological methodology, documentation, the analysis of the finds, and the presentation of the results. It is followed by Chapter 2, devoted to the architecture of the house and a room-by-room analysis, with detailed description of the building techniques, materials, and features, including the wall-paintings. Chapter 3 enters into the details of the stratigraphy of the house and the adjacent streets, with the interpretation of the formation processes and materials found. The same scheme is followed in Chapter 4 for the stratigraphy of test trenches below the house. Chapter 5 is a synthetic discussion of our major findings with respect to the house, its associated finds, and the post-abandonment phase, framed in a regional context, with comparisons to late antique dwellings and sites elsewhere. The volume is illustrated with photographs, plans, sections, 3D reconstructions, and photogrammetric projections"--