The U.S. food safety system is in crisis. Approx. 76 million Americans -- one in four -- are sickened by foodborne disease each year. Of these, an estimated 325,000 are hospitalized, and 5,000 die. This report discusses the top concerns about food safety that experts have identified and addresses the food safety functions within the Dept. of Health and Human Services (HHS). Contents: (1) Food Safety Programs at HHS: The Current Structure; (2) Current HHS Food Safety Functions Do Not Meet Today¿s Threats; (3) The Benefits of Aligning Food Safety Functions at HHS; (4) Background on Reform Efforts; (5) Recommendations: Making Food Safety a Priority at HHS; (6) A Staged Pathway to Comprehensive Food Safety Reform. Illus.