Physical pharmaceutics is a foundational area of pharmacy that deals with the principles underlying the physical and chemical properties of drugs and drug delivery systems. Here are some key topics typically covered in Physical Pharmaceutics I: The fundamental properties of drug substances such as solubility, stability, surface & interfacial phenomena, rheology, micrometrics, & complexation which will give a lead in formulating drug substances into suitable dosage forms. In addition, it includes ICH guidelines for stability testing and also suggestions for practical’s wherever necessary. Moreover, the language is so simple that grantees more clarity than brevity, We do hope the presentation will motivate self study.