Tu Youyou's Journey in the Search for Artemisinin is an autobiographical science book chronicling in detail the great experiences of Tu Youyou from her childhood to winning the Nobel Prize in Physiology or Medicine.As Tu Youyou is the first female scientist from China to win the Nobel Prize in Physiology or Medicine, this win created a sudden wave of interest in medicine, resulting in numerous autobiographical books about Tu Youyou appearing on the market. Contrary to these mass market titles, this book is uniquely different as it is fully authorized by the Nobel laureate herself. Her once-confidential experimental data and Artemisinin research reports are now revealed in this book for all to learn and comprehend. In addition, one of the book authors, Dr Wang Manyuan, is the only PhD student supervised by Professor Tu.Pharmaceutical researchers can use the book's valuable contents to reference, quote and analyse while searching for their own scientific inspirations. It also successfully serves as a guide for budding scientists and future Nobel Prize winners as it provides the proper guidance and methods of scientific research.
Each major technological innovation will open up a new era for human transportation. The closer integration of 5G technology with AI, Big Data, Cloud Computing, and IOT serves as a catalyst to many technological innovations.This book looks at these innovations underpinned by 5G technology to enable the transportation system to be smart and intelligent, and how these new innovations will help to shape transportation system in the future.
The motion of the train depends on the traction of linear motors in the vehicle. This book describes a number of essential technologies that can ensure the safe operation of Maglev trains, such as suspension and orientation technologies, network control and diagnosis technologies. This book is intended for researchers, scientists, engineers and graduate students involved in the rail transit industry, train control and diagnosis, and Maglev technology.
The book provides an overview of III-nitride-material-based light-emitting diode (LED) technology, from the basic material physics to the latest advances in the field, such as homoepitaxy and heteroepitaxy of the materials on different substrates. It also includes the latest advances in the field, such as approaches to improve quantum efficiency and reliability as well as novel structured LEDs. It explores the concept of material growth, chip structure, packaging, reliability and application of LEDs. With spectra coverage from ultraviolet (UV) to entire visible light wavelength, the III-nitride-material-based LEDs have a broad application potential, and are not just limited to illumination. These novel applications, such as health & medical, visible light communications, fishery and horticulture, are also discussed in the book.
“Clinical Cases of Digestive System” collected 14 difficult cases of digestive system, each case from the clinical diagnosis and treatment process, diagnosis and treatment difficulties, knowledge review, references are introduced, the content is wonderful, worth reading. This book has the following features: 1 case was representative. Twelve cases were selected from the Department of Gastroenterology. 2 Cases covered a wide range of organs of the digestive system. The case analysis was wonderful, with both the tortuous diagnosis and treatment and the logical outcome. 3 The knowledge points of the cases are clear. There are not only the summary of difficult points, but also the wonderful comments of domestic well-known experts, and each case is attached with references, which is convenient for readers to further study. The book collects the clinical experience and wisdom of the gastroenterologists, has important reference value for the cultivation of the clinical diagnosis and treatment thinking ability of young doctors, is suitable for the reading of the general training doctors, advanced students and graduate students of the general digestive specialty, and is suitable for the digestive specialist doctors with certain clinical experience. It is also a good book to expand the clinical horizon. In clinical practice, each case has both the commonness of the same disease and the particularity of the patient, so the diagnosis and treatment process is full of uncertainty. The cases in this book are no exception. Some cases may have different, or even better, treatment routes. Given the editor’s theoretical level and clinical experience, there are bound to be imperfections or errors. The majority of readers are generous in giving advice.
Coherent Control of Four-Wave Mixing" discusses the frequency, temporal and spatial domain interplays of four-wave mixing (FWM) processes induced by atomic coherence in multi-level atomic systems. It covers topics in five major areas: the ultrafast FWM polarization beats due to interactions between multi-color laser beams and multi-level media; coexisting Raman-Rayleigh-Brillouin-enhanced polarization beats due to color-locking noisy field correlations; FWM processes with different kinds of dual-dressed schemes in ultra-thin, micrometer and long atomic cells; temporal and spatial interference between FWM and six-wave mixing (SWM) signals in multi-level electromagnetically induced transparency (EIT) media; spatial displacements and splitting of the probe and generated FWM beams, as well as the observations of gap soliton trains, vortex solitons, and stable multicomponent vector solitons in the FWM signals. The book is intended for scientists, researchers, advanced undergraduate and graduate students in Nonlinear Optics. Dr. Yanpeng Zhang is a professor and Zhiqiang Nie is a Ph. D. student at the Key Laboratory for Physical Electronics and Devices of the Ministry of Education, Xi'an Jiaotong University, China. Dr. Min Xiao is a professor of physics at the University of Arkansas, Fayetteville, U.S.A.
In reviewing and reconsidering the intellectual history of scientism and antiscientism, the authors assess the process of reasoning and prejudices of these contrasting viewpoints, while discussing the repercussions of scientific hegemony and its contemporary criticism. As the second volume of a three-volume set that proposes to reconsider science and technology and explores how the philosophy of science and technology responds to an ever-changing world, this title focuses on ideological trends centering around scientism and anti-scientism since the 19th century. The six chapters look into the emergence of scientism, instrumental reason, scientific optimism, scientific pessimism, scientific crisis and irrationalism and finally the deconstruction of scientism. The authors provide insight into the connections and biases of these disparate views and critiques, explore the influences of the hegemony of science and contemporary critique of science and evaluate the value of postmodernism and deconstructivism. The volume will appeal to scholars and students interested in the philosophy of science and technology, the ideology of scientism and anti-scientism, modernism and postmodernism, Marxist philosophy and topics related to scientific culture.
This book reviews the state-of-the-art in combinatorial testing, with particular emphasis on the automatic generation of test data. It describes the most commonly used approaches in this area - including algebraic construction, greedy methods, evolutionary computation, constraint solving and optimization - and explains major algorithms with examples. In addition, the book lists a number of test generation tools, as well as benchmarks and applications. Addressing a multidisciplinary topic, it will be of particular interest to researchers and professionals in the areas of software testing, combinatorics, constraint solving and evolutionary computation.
Eine vielversprechende Technologie zur Maximierung der Bandbreiteneffizienz in der breitbandigen drahtlosen Kommunikation ist die Raum-Zeit-Kodierung. Theorie und Praxis verbindend, ist dieses Buch die erste umfassende Diskussion von Grundlagen und designorientierten Aspekten von Raum-Zeit-Codes. Single-Carrier und Multi-Carrier-Übertragungen für Einzel- und Mehrnutzerkommunikation werden behandelt.
This book presents a series of new topologies and modulation schemes for soft-switching in isolated DC–DC converters. Providing detailed analyses and design procedures for converters used in a broad range of applications, it offers a wealth of engineering insights for researchers and students in the field of power electronics, as well as stimulating new ideas for future research.
Given their key position in the process control industry, process monitoring techniques have been extensively investigated by industrial practitioners and academic control researchers. Multivariate statistical process control (MSPC) is one of the most popular data-based methods for process monitoring and is widely used in various industrial areas. Effective routines for process monitoring can help operators run industrial processes efficiently at the same time as maintaining high product quality. Multivariate Statistical Process Control reviews the developments and improvements that have been made to MSPC over the last decade, and goes on to propose a series of new MSPC-based approaches for complex process monitoring. These new methods are demonstrated in several case studies from the chemical, biological, and semiconductor industrial areas. Control and process engineers, and academic researchers in the process monitoring, process control and fault detection and isolation (FDI) disciplines will be interested in this book. It can also be used to provide supplementary material and industrial insight for graduate and advanced undergraduate students, and graduate engineers. Advances in Industrial Control aims to report and encourage the transfer of technology in control engineering. The rapid development of control technology has an impact on all areas of the control discipline. The series offers an opportunity for researchers to present an extended exposition of new work in all aspects of industrial control.
Analysis and Control of Boolean Networks presents a systematic new approach to the investigation of Boolean control networks. The fundamental tool in this approach is a novel matrix product called the semi-tensor product (STP). Using the STP, a logical function can be expressed as a conventional discrete-time linear system. In the light of this linear expression, certain major issues concerning Boolean network topology – fixed points, cycles, transient times and basins of attractors – can be easily revealed by a set of formulae. This framework renders the state-space approach to dynamic control systems applicable to Boolean control networks. The bilinear-systemic representation of a Boolean control network makes it possible to investigate basic control problems including controllability, observability, stabilization, disturbance decoupling etc.
Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.
The foundation for targeted therapy of cancers driven by members of the ErbB oncoprotein family was established initially by the demonstration that ectodomain binding monoclonal antibodies (mAb) could disable the protein kinase encoded by the HER2/neu oncogene. Homomeric and heteromeric erbB kinases play critical roles in the development of cancer and in the spread of early lesions. In particular, antibodies targeting the p185erbB2/neu receptor provide major clinical benefits in the treatment of breast cancer and also stomach cancer. As suggested by our study with oncogenic neu transgenic mice, anti-p185erbB2/neu antibodies are also effective in preventing the tissue hyperplasia that precedes tumorigenesis, tumor growth and the dissemination of ErbB2/neu kinase-positive cells into other tissues. As a therapeutic principle, “reversion of phenotype” for established tumors and “prevention” of tumorigenesis and spread can explain the basis for the benefits invoked by therapeutic and adjuvant therapies for breast cancer patients after cancers are surgically removed. These emerging principles being enlightened by ongoing studies of monoclonal antibody therapy will continue to provide guidance for the development of new targeted therapies for resistant tumors that arise after treatment.
This book provides a comprehensive illustration to the superplastic forming/diffusion bonding (SPF/DB) technology developed over decades of research on titanium alloys, process modeling, and its application. SPF/DB technology plays key roles in building aviation components with complicated structures, with highly beneficial effects when well designed. With the ever-increasing demand on components with multiple layers, there is an urgent need for an updated assessment of traditional and modern SPF/DB processing methods. Success critically depends on making the most practical and effective choice of SPF/DB method for a given application. The book introduces titanium and titanium alloys, SPF/DB processing and its modeling, and applications for building typical single or multiple layer(s) structures. Particular attention is paid to illustrating the microstructure evolution during SPF/DB processes. The information for making technical decisions about optimal choice of measurement and evaluation methods is also given in the book. Each chapter follows a focused and pragmatic format. Fully illustrated throughout, the book presents the state of the art in SPF/DB technology in a manner that makes it useful for engineers to improve the established forming processes and quality of components. This book is an essential reading material for industrial practitioners, academic researchers and postgraduates.
This book describes the algorithms, validation and preliminary analysis of the Global LAnd Surface Satellite (GLASS) products, a long-term, high-quality dataset that is now freely available worldwide to government organizations and agencies, scientific research institutions, students and members of the general public. The GLASS products include leaf area index, broadband albedo, broadband emissivity, downward shortwave radiation and photosynthetically active radiation. The first three GLASS products cover 1981 to 2012 with 1km and 5km spatial resolutions and 8-day temporal resolution, and the last two GLASS products span 2008 to 2010 with 3-hour temporal resolution and 5km spatial resolution. These GLASS products are unique. The first three are spatially continuous and cover the longest period of time among all current similar satellite products. The other two products are the highest spatial-resolution global radiation products from satellite observations that are currently available. These products can be downloaded from Beijing Normal University at http://glass-product.bnu.edu.cn/ and the University of Maryland Global Land Cover Facility at http://www.glcf.umd.edu/ The GLASS products are the outcome of a key research project entitled “Generation & Applications of Global Products of Essential Land Variables”, supported by funding from the High-Tech Research and Development Program of China and involving dozens of institutions and nearly one hundred scientists and researchers. Following an introduction, the book contains five chapters corresponding to these five GLASS products: background, algorithm, quality control and validation, preliminary analysis and applications. It discusses the long-term environmental changes detected from the GLASS products and other data sources at both global and local scales and also provides detailed analysis of regional hotspots where environmental changes are mainly associated with climate change, drought, land-atmosphere interactions, and human activities. The book is based primarily on a set of published journal papers about these five GLASS products and includes updated information. Since these products have now begun to be widely used, this book is an essential reference document. It is also a very helpful resource to anyone interested in satellite remote sensing and its applications.
The inverse design approach is new to the built environment research and design community, though it has been used in other industries including automobile and airplane design. This book, from some of the pioneers of inverse design applications in the built environment, introduces the basic principles of inverse design and the specific techniques that can be applied to built environment systems. The authors' inverse design concept uses the desired enclosed environment as the design objective and inversely determines the systems required to achieve the objective. The book discusses a number of backward and forward methods for inverse design. Backward methods, such as the quasi-reversibility method, the pseudo-reversibility method, and the regularized inverse matrix method, can be used to identify contaminant sources in an enclosed environment. However, these methods cannot be used to inversely design a desired indoor environment. Forward methods, such as the computational-fluid-dynamics (CFD)-based genetic algorithm (GA) method, the CFD-based adjoint method, the CFD-based artificial neural network (ANN) method, and the CFD-based proper orthogonal decomposition (POD) method, show the promise in the inverse design of airflow and heat transfer in an enclosed environment. The book describes the fundamentals of the methods for beginners, provides exciting design examples for the reader to duplicate, discusses the pros and cons of each design method and points out the knowledge gaps for further development.
This book assesses various intelligent-city evaluation systems around the globe, and subsequently combines that assessment with local-government and enterprise practices to create an evaluation index system for quantifying the Intelligent City concept. In addition, the book provides the results of the CityIQ indicator ranking of intelligent cities in China and worldwide, a system that focuses on three of the most crucial aspects of urban development: the development environment, future trends, and construction and operation. After data sorting, calculation and dimensionless treatment, a score system ranging from 0 to 100 is created for ranking and analyzing cities. Providing unique strategies for promoting an intelligent city evaluation system, the book offers a valuable reference guide for intelligent-city decision-makers, as well as leaders in public urban economy, social welfare and environmental authorities.
Multi-carrier technologies have emerged as important instruments in telecommunications. OFDM is in the forefront, with its adoption by the IEEE 802.11 standards committee and the European HYPERLAN standards group. Following OFDM, MC-CDMA is also demonstrating considerable promise when compared to competing technologies. According to the authors, these technologies are just the beginning in the coming multi-carrier revolution. In Multi-Carrier Technologies for Wireless Communication, the authors explain how a common multi-carrier platform is being designed for DS-CDMA, TDMA, OFDM and MC-CDMA systems. Findings are presented which show how this multi-carrier platform enhances network capacity and probability of error performance.Specific results include (1) innovation in multi-carrier technologies that are enabling them to become an integral part of TDMA and DS-CDMA systems; and (2) the design of multi-carrier systems to overcome PAPR problems (in, e.g., OFDM). Multi-Carrier Technologies for Wireless Communication is an important book for engineers who work with DS-CDMA, TDMA, OFDM, or MC-CDMA systems, and are seeking new ways of exploiting the wireless medium based on a "smarter" signal processing.
This book assesses various intelligent-city evaluation systems around the globe, and subsequently combines that assessment with local-government and enterprise practices to create an evaluation index system for quantifying the Intelligent City concept. In addition, the book provides the results of the CityIQ indicator ranking of intelligent cities in China and worldwide, a system that focuses on three of the most crucial aspects of urban development: the development environment, future trends, and construction and operation. After data sorting, calculation and dimensionless treatment, a score system ranging from 0 to 100 is created for ranking and analyzing cities. Providing unique strategies for promoting an intelligent city evaluation system, the book offers a valuable reference guide for intelligent-city decision-makers, as well as leaders in public urban economy, social welfare and environmental authorities.
Multi-carrier technologies have emerged as important instruments in telecommunications. OFDM is in the forefront, with its adoption by the IEEE 802.11 standards committee and the European HYPERLAN standards group. Following OFDM, MC-CDMA is also demonstrating considerable promise when compared to competing technologies. According to the authors, these technologies are just the beginning in the coming multi-carrier revolution. In Multi-Carrier Technologies for Wireless Communication, the authors explain how a common multi-carrier platform is being designed for DS-CDMA, TDMA, OFDM and MC-CDMA systems. Findings are presented which show how this multi-carrier platform enhances network capacity and probability of error performance.Specific results include (1) innovation in multi-carrier technologies that are enabling them to become an integral part of TDMA and DS-CDMA systems; and (2) the design of multi-carrier systems to overcome PAPR problems (in, e.g., OFDM). Multi-Carrier Technologies for Wireless Communication is an important book for engineers who work with DS-CDMA, TDMA, OFDM, or MC-CDMA systems, and are seeking new ways of exploiting the wireless medium based on a "smarter" signal processing.
Skillfully blending Eastern and Western Thought, Mater Yang illuminates the traditional teachings as well as offers scientific explanations and a contemporary understanding of Taiji practice. In this book, Yang describes the core exercises that form the foundation of Taiji practice, and explains the purpose and necessary integration of these exercises to achieve the full health and martial, physical and spiritual benefits of Taiji training. As both a traditionally trained expert of Taijiquan and a scientist studying the mechanisms and benefits of Taiji practice, Yang uniquely demystifies Taijiquan and makes it more accessible to a Wwestern audience. Carefully preserving and drawing from classical Taiji writings and the oral traditions of the Chinese martial arts community, Yang also suggests ground-breaking hypothesis to explain the mechanisms of how and why Taiji practices are so widely beneficial. This book is valuable to both beginning and advanced practitioners.
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