Ghrelin and the ghrelin receptor (GHSR1a) play a central role in growth hormone secretion, food intake, energy metabolism, and other important functions. This book summarizes the present situation of the GHSR1a gene polymorphisms and their genetic effects on growth and fatty acid component traits in domestic animals, humans and rodents. It highlights a unique molecular evolution of the GHSR1a gene among animal species, and its significant genetic and epistatic effects on carcass and fatty acid component traits in a sex-dependent fashion. The volume also shows the overdominance effect of the GHSR1a-DelR242 locus on growth and its molecular mechanisms and the central role of the bovine GHSR1a_5’UTR-(TG) repeat locus in growth and fatty acid component traits in cattle.
The rapid increase in global services during the last few decades is without doubt one of the most challenging social, cultural, political, and especially economic, forces of our time. Services have supplanted agriculture, manufacturing and resources, as the primary source of international competitive advantage in many countries, providing wealth, employment, and almost unlimited future opportunities for growth, whether in traditional or more innovative forms. This book explores the strategic management of services through an Integrated Services Management Model which links operational, marketing, financial and human resource management functions, within a broad and diverse collection of international, regional, and local service contexts. It contains numerous case examples, student projects and exercises, designed to illustrate common problems and innovative approaches, with a particular focus on the Asia Pacific and Australasian regions.
Electronic state of every solid is basically classified into two categories according to its electrical responses: insulator or metal. A textbook of modern solid state physics explains that shape of a Fermi surface plays a key role in most physical properties in metals. One of the well-established experimental methods to detect a Fermi surface is measurement of quantum oscillations that is a periodic response of physical quantities with respect to external magnetic fields. As insulators do not host Fermi surface, it is believed that they do not exhibit any quantum oscillations. This book presents a comprehensive review of recent observations of quantum oscillations in the Kondo insulators, SmB6 and YbB12, and discusses how the observations are demonstrated by a newly proposed mechanism where emergent charge-neutral fermions exhibit quantum oscillations instead of bare electrons. It also focuses on topological properties of Kondo insulators, and demonstrates that YbB12 hosts a surface metallic conduction owing to its non-trivial band structure. Further it presents the experiments of specific heat and thermal conductivity in YbB12 down to ultra-low temperature to discuss the possible low-energy excitations from a Fermi surface of neutral fermions. The demonstrated gapless and itinerant fermionic excitations, that is the significant contribution from charge neutral fermions, violates Wiedemann-Franz law. The discoveries point out a highly unconventional phase of quantum state—electrically insulating but thermally metallic—realized in the bulk of topological Kondo insulators.
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