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Validamycin and Its Derivatives

Discovery, Chemical Synthesis, and Biological Activity

By: Xiaolong Chen,Yuele Lu,Yongxian Fan,Yinchu Shen

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Validamycin and Its Derivatives

Discovery, Chemical Synthesis, and Biological Activity

By: Xiaolong Chen,Yuele Lu,Yongxian Fan,Yinchu Shen

Validamycin and Its Derivatives: Discovery, Chemical Synthesis and Biological Activity presents, for the first time, a complete review of the underlying chemistry, synthesis, behavior and application of these compounds. Beginning with an introduction to validamycin, the book then outlines the key elements of its discovery and production, including details of its structures, isolation, analysis, and issues relating to its large scale production. Biological activities are then explored in more detail, followed by details of biosynthesis. Further to this, the chemical synthesis of validamycin and its intermediates, including valienamine, validamine, valiolamine, and validoxylamines is reviewed, before preparation of these derivatives and their biological activities are explored. Finally, the book concludes with a discussion of the economic aspects of working with validamycin and its potential in future applications and trends. With its detailed chemical coverage from a team of expert authors, this detailed guide can be applied to the large-scale industrial production of antibiotics and the adaptation of bioactive agents, from agricultural, to novel pharmaceutical applications. - Offers complete coverage of validamycin chemistry from a highly experienced team of authors - Encourages the discovery of further novel drugs based on validamycin derivatives - Presents an interesting model for establishing new pharmaceutical leads from agricultural sources - Includes coverage of the total chemical synthesis of validamycin and its intermediates, including valienamine, validamine, valiolamine and validoxylamines

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Page Count

342

Publisher

Elsevier

Published Date

ISBN 10

008101113X

ISBN 13

9780081011133

Validamycin and Its Derivatives

Discovery, Chemical Synthesis, and Biological Activity

By: Xiaolong Chen,Yuele Lu,Yongxian Fan,Yinchu Shen

Write a review Read reviews Take a Quiz Solve Book Puzzle

Validamycin and Its Derivatives

Discovery, Chemical Synthesis, and Biological Activity

By: Xiaolong Chen,Yuele Lu,Yongxian Fan,Yinchu Shen

Validamycin and Its Derivatives: Discovery, Chemical Synthesis and Biological Activity presents, for the first time, a complete review of the underlying chemistry, synthesis, behavior and application of these compounds. Beginning with an introduction to validamycin, the book then outlines the key elements of its discovery and production, including details of its structures, isolation, analysis, and issues relating to its large scale production. Biological activities are then explored in more detail, followed by details of biosynthesis. Further to this, the chemical synthesis of validamycin and its intermediates, including valienamine, validamine, valiolamine, and validoxylamines is reviewed, before preparation of these derivatives and their biological activities are explored. Finally, the book concludes with a discussion of the economic aspects of working with validamycin and its potential in future applications and trends. With its detailed chemical coverage from a team of expert authors, this detailed guide can be applied to the large-scale industrial production of antibiotics and the adaptation of bioactive agents, from agricultural, to novel pharmaceutical applications. - Offers complete coverage of validamycin chemistry from a highly experienced team of authors - Encourages the discovery of further novel drugs based on validamycin derivatives - Presents an interesting model for establishing new pharmaceutical leads from agricultural sources - Includes coverage of the total chemical synthesis of validamycin and its intermediates, including valienamine, validamine, valiolamine and validoxylamines

Average ratings

N/A

5

0%

4

0%

3

0%

2

0%

1

0%

Solve jigsaw puzzle

Age

Page Count

342

Publisher

Elsevier

Published Date

ISBN 10

008101113X

ISBN 13

9780081011133