In this PhD thesis, Yue Yanan addresses a long-overlooked and critical question in the development of non-viral vectors for gene delivery. The author determines that those uncomplexed and cationic polymer chains free in the solution mixture of polymer and DNA facilitate and promote gene transfection. Furthermore, by using a combination of synthetic chemistry, polymer physics and molecular biology, Yue confirms that it is those cationic polymer chains free in the solution mixture, rather than those bound to DNA chains, that play a decisive role in intracellular trafficking. Instead of the previously proposed and widely accepted “proton sponge” model, the author's group propose a new hypothesis based on the results of several well-designed and decisive experiments. These results show that free polycationic chains with a length of more than ~10 nm are able to partially block the fusion between different endocytic vesicles, including the endocytic-vesicle-to-endolysosome pathway. This thesis is highly original and its results greatly deepen our understanding of polymer-mediated gene transfection. More importantly, it provides new insights into the rational design of next-generation superior polymeric gene-delivery vectors.
What is reality? The reality is that there are only one or two moments in life that are wonderful.What is a novel? The novel is the protagonist's life again and again wonderful;What do you do when you are alone in a strange world, when you have the power to shock the world, when you cry like a ghost, when you have the medical skills to achieve perfection, when you have the skills to return to the world?Will you bring beauty to the world?You will fight for hegemony and point the finger at the world?You will roam the martial arts world and you will be filled with kindness and hatred? Let us follow the steps of the protagonist, and experience the brilliance again and again
Immortal Manifestation King Yang Xu, reborn back to the city. The blood debt from his past life was now repaid with his life. This time, he had to make up for everything he had missed. Where the three-foot-tall mountain was heading towards, the Gods and Buddha would retreat!
Drawing on narrative works acoss a century and across Chinese and Chinese-American cultural lines, Yue examines Chinese cultural politics of the twentieth century as an "alimentary discourse," where the roles of food and "eating" wi
To the Storm by Yue Daiyun and Carolyn Wakeman is the fascinating story of Yue Daiyun, a faculty member at Beijing University. Yue Daiyun was a revolutionary from her early school days. She had been a child during the anti-Japanese war and hated the Guomundang. Accepted as a student at Beida in 1948, she joined the Communist Party's underground Democratic youth League and became a Party member the following year and helped with the Liberation of Beijing ... In this interesting autobiography, Yue Daiyun tells her story of the life she and her family lived during these somewhat violent and terror-filled years in China."--Amazon.com
This book systematically studies the literary output of female writers in contemporary China within the frame of literary theories of feminism. With tools from psychoanalysis, structuralism and deconstructionism, the two female authors, Meng and Dai, analyze 9 important female writers from 1919 to 1949, including Yin Lu, Xin Bing, Ning Ding, Ailing Zhang. By decade, the authors provide a comprehensive depiction of these female writers' historic-cultural background as well as their reception by critics and audiences. Navigating the complex relation between mainstream literary trends and female writers’ practice, this text represents a landmark of practice of literary feminist criticism within the Chinese language.
This book mainly provides the current status of water pollution faced by China under rapid changing environment and the actions that have been taken for prevention and treatment of water pollution. It points out that the water pollution situation is severe. Facing water pollution, China’s experiences include several aspects on source control and pollution interception, internal nutrient removal of sediment, ecological restoration, and water transfer policy. There exists both the opportunity and challenge for the prevention and control of water pollution in China. The book contains numerous charts and diagrams which further illustrating China’s paths to clean water.
This book introduces Python programming language and fundamental concepts in algorithms and computing. Its target audience includes students and engineers with little or no background in programming, who need to master a practical programming language and learn the basic thinking in computer science/programming. The main contents come from lecture notes for engineering students from all disciplines, and has received high ratings. Its materials and ordering have been adjusted repeatedly according to classroom reception. Compared to alternative textbooks in the market, this book introduces the underlying Python implementation of number, string, list, tuple, dict, function, class, instance and module objects in a consistent and easy-to-understand way, making assignment, function definition, function call, mutability and binding environments understandable inside-out. By giving the abstraction of implementation mechanisms, this book builds a solid understanding of the Python programming language.
What does the state do when public expectations exceed its governing capacity? The Performative State shows how the state can shape public perceptions and defuse crises through the theatrical deployment of language, symbols, and gestures of good governance—performative governance. Iza Ding unpacks the black box of street-level bureaucracy in China through ethnographic participation, in-depth interviews, and public opinion surveys. She demonstrates in vivid detail how China's environmental bureaucrats deal with intense public scrutiny over pollution when they lack the authority to actually improve the physical environment. They assuage public outrage by appearing responsive, benevolent, and humble. But performative governance is hard work. Environmental bureaucrats paradoxically work themselves to exhaustion even when they cannot effectively implement environmental policies. Instead of achieving "performance legitimacy" by delivering material improvements, the state can shape public opinion through the theatrical performance of goodwill and sincere effort. The Performative State also explains when performative governance fails at impressing its audience and when governance becomes less performative and more substantive. Ding focuses on Chinese evidence but her theory travels: comparisons with Vietnam and the United States show that all states, democratic and authoritarian alike, engage in performative governance.
After the hedonistic young master was drawn into the conflict between the two factions both sides wanted to mess with him the firepower was so strong He wasn't afraid of doing anything when he stomped the evil sect he slapped their decent faces and said — go to hell
Xie E, a A Peerless Genius born in a family of tomb robbers, died in an air disaster and entered the Underworld's reincarnation cycle Dao. He was reincarnated as a "quasi eunuch" in the Northern Song Dynasty's last palace.
If you choose a music, you really choose a life. If you choose rock and roll, your youth will be destined to be different! Qin Fengge's dream was to become a world-renowned rock star ...
This book deconstructs a series of myths surrounding China’s economic rise. The first myth is that globalization led directly to China’s rise; the second is that China is another East Asian developmental state; the third that China’s market reform had been implemented in an incremental way; and fourth that China’s ‘resilient authoritarianism’ has been effective in ensuring the country’s economic and political transformation. Yue argues that the China model is one of ‘crony comprador capitalism’ that has hindered the country’s attempts at economic and political modernity. It is argued that the United States’ strategy of integrating China into the international system is self-defeating in the long run; not because such an approach has created a 'restless empire' capable of challenging US primacy, but because the Chinese 'miracle' has subsequently backfired on the liberal order created after World War Two. Covering the entire reform period from the end of the Cultural Revolution in 1976 to the present day, the author calls for readers to rethink globalization and leave more policy space for China and the developing nations to pursue national development through internal integration, which is more conducive to democratic transition and global peace.
If a woman wanted revenge, what other weapons could she use other than her body?When she met him, she was the daughter of a traitor who had been exterminated.When he met her, he was the king of the pirates;He pitied her, he doted on her, but in her eyes he was a demon that took over her body and freedom.There were two reasons for her survival: to kill the ruler of her people, and to kill the pirates who had tainted her life.And years later, when the Dwarf had been captured and the pirates were overpowering, this drifting feeling would rest in whose heart.
In Imperial China, the idea of filial piety not only shaped family relations but was also the official ideology by which Qing China was governed. In State and Family in China, Yue Du examines the relationship between politics and intergenerational family relations in China from the Qing period to 1949, focusing on changes in family law, parent-child relationships, and the changing nature of the Chinese state during this period. This book highlights how the Qing dynasty treated the state-sponsored parent-child hierarchy as the axis around which Chinese family and political power relations were constructed and maintained. It shows how following the fall of the Qing in 1911, reform of filial piety law in the Republic of China became the basis of state-directed family reform, playing a central role in China's transition from empire to nation-state.
Lei Ao, who was born with the possession of a vicious beast, possessed a power that even he couldn't control. After unintentionally obtaining the Bloodthirsty Demon Saber, his fate had been completely changed. You have a magical equipment? I stole from you! Do you have an unparalleled divine art? It's still you! The number one beauty in the world? You will chase after him if you have something to eat! The most handsome guy in the world? I'll turn you into a pig head right now! Wielding the Bloodthirsty Demon Saber, stepping on the Fifth Constellation Diagram, using the Heaven Collapsing Hand to destroy the heaven and earth, using peerless domineering aura to descend upon the cultivation world! The previous book (Monarch of this world) has been completed. Please be at ease with your collection of new books! Close]
Drawing on narrative works acoss a century and across Chinese and Chinese-American cultural lines, Yue examines Chinese cultural politics of the twentieth century as an "alimentary discourse," where the roles of food and "eating" wi
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