You only have to tell me, do you still want to be the Qiao Clan's daughter that returns to her glory, do you want to be slapped in the face by those who betrayed you and humiliated you? Hmm?""You mean... You can help me take revenge? ""As my woman, I can give you everything you want!"To Qiao Xiao Xiao, who had been abandoned at the wedding after her father had taken a drug jump, a man's words were like a spell.She held the man's outstretched hand, thinking that this would be the rest of her life.
Drug development is an iterative process. The recent publications of regulatory guidelines further entail a lifecycle approach. Blending data from disparate sources, the Bayesian approach provides a flexible framework for drug development. Despite its advantages, the uptake of Bayesian methodologies is lagging behind in the field of pharmaceutical development. Written specifically for pharmaceutical practitioners, Bayesian Analysis with R for Drug Development: Concepts, Algorithms, and Case Studies, describes a wide range of Bayesian applications to problems throughout pre-clinical, clinical, and Chemistry, Manufacturing, and Control (CMC) development. Authored by two seasoned statisticians in the pharmaceutical industry, the book provides detailed Bayesian solutions to a broad array of pharmaceutical problems. Features Provides a single source of information on Bayesian statistics for drug development Covers a wide spectrum of pre-clinical, clinical, and CMC topics Demonstrates proper Bayesian applications using real-life examples Includes easy-to-follow R code with Bayesian Markov Chain Monte Carlo performed in both JAGS and Stan Bayesian software platforms Offers sufficient background for each problem and detailed description of solutions suitable for practitioners with limited Bayesian knowledge Harry Yang, Ph.D., is Senior Director and Head of Statistical Sciences at AstraZeneca. He has 24 years of experience across all aspects of drug research and development and extensive global regulatory experiences. He has published 6 statistical books, 15 book chapters, and over 90 peer-reviewed papers on diverse scientific and statistical subjects, including 15 joint statistical works with Dr. Novick. He is a frequent invited speaker at national and international conferences. He also developed statistical courses and conducted training at the FDA and USP as well as Peking University. Steven Novick, Ph.D., is Director of Statistical Sciences at AstraZeneca. He has extensively contributed statistical methods to the biopharmaceutical literature. Novick is a skilled Bayesian computer programmer and is frequently invited to speak at conferences, having developed and taught courses in several areas, including drug-combination analysis and Bayesian methods in clinical areas. Novick served on IPAC-RS and has chaired several national statistical conferences.
A comparative look at North and South Korea's political and economic institutions and processes, and an examination of their evolution since 1945. Problems such as leadership succession, democratization, nuclear weapons, education and reunification are explored.
A poor laborer who couldn't even afford the rent was in a car accident. However, the heavens were blessed by the heavens. In this car accident, he unexpectedly obtained the Heaven and Earth Mysterious Yellow Limitless Body and became a prodigy. The city, the immortal world, the divine world, the void world, I will do whatever I want. After the protagonist obtained his superpower, he entered the cultivation world and became arrogant. So what if I laugh at my own knife pride? The law of all living things in the world can only be looked down upon by me! And to see how the powerful young man would rule the world...
This book employs a biographical approach to comprehensively study a set of Tang era-tomb guardian figurines, known as the Four Gods (Sishen), comprising a pair of warriors (Dangkuang and Dangye) and a pair of hybrid beasts (Zuming and Dizhou). These objects were exclusively used by officials until 841 AD and were mainly found in capitals then. They disappeared in the 9th century AD. The book is divided into three sections. Part one focuses on their symbolism through names, images, burial contexts, associated ritual regulations, and the interplay of all of these, revealing their dual significance – apotropaic and political, tied to ritual propriety, nuo exorcism, yin-yang divination, and more. Part two explores their connection to other supernatural tomb figurines in the early and middle Tang periods, challenging previous theories and highlighting regional standardization. Additionally, this part delves into the Four Gods’ regulated production, government oversight, and role in funerary processions. Part three examines their disappearance due to shifting views on the afterlife and diminishing national power. It also explores changes in the usage of related tomb objects after the Tang era, focusing on protective functions and spatial concepts.
This two-volume work presents state-of-the-art mathematical theories and results on infinite-dimensional dynamical systems. Inertial manifolds, approximate inertial manifolds, discrete attractors and the dynamics of small dissipation are discussed in detail. The unique combination of mathematical rigor and physical background makes this work an essential reference for researchers and graduate students in applied mathematics and physics. The main emphasis in the first volume is on the mathematical analysis of attractors and inertial manifolds. This volume deals with the existence of global attractors, inertial manifolds and with the estimation of Hausdorff fractal dimension for some dissipative nonlinear evolution equations in modern physics. Known as well as many new results about the existence, regularity and properties of inertial manifolds and approximate inertial manifolds are also presented in the first volume. The second volume will be devoted to modern analytical tools and methods in infinite-dimensional dynamical systems. Contents Attractor and its dimension estimation Inertial manifold The approximate inertial manifold
This book has been written with the support of Huawei's large accumulation of technical knowledge and experience in the WLAN field, as well as its understanding of customer service requirements. First, the book covers service challenges facing enterprise wireless networks, along with detailing the latest evolution of Wi-Fi standards, air interface performance, and methods for improving user experience in enterprise scenarios. Furthermore, it illustrates typical networking, planning, and scenario-specific design for enterprise WLANs, and provides readers with a comprehensive understanding of enterprise WLAN planning, design, and technical implementation, as well as suggestions for deployment. This is a practical and easy-to-understand guide to WLAN design, and is written for WLAN technical support and planning engineers, network administrators, and enthusiasts of network technology. Authors Rihai Wu is Chief Architect of Huawei's campus network WLAN solution with 16 years of experience in wireless communications product design and a wealth of expertise in network design and product development. He previously served as a designer and developer of products for Wideband Code Division Multiple Access (WCDMA), LTE indoor small cells, and WLAN. Xun Yang is a WLAN standard expert from Huawei. He has nine years of experience in formulating WLAN standards, and previously served as 802.11ac Secretary, 802.11ah PHY Ad-hoc Co-chair, and 802.11ax MU Ad Hoc Sub Group Co-chair. Mr. Yang oversees technical research, the promotion of standards, and industrialization in the WLAN field, and has filed more than 100 patents. Xia Zhou is a documentation engineer of Huawei's campus network WLAN solution. She has 10 years of experience in creating documents for campus network products. Ms. Zhou was previously in charge of writing manuals for Huawei data center switches, WLAN products, and campus network solutions. She is also the author of Campus Network Solution Deployment Guide and was a co-sponsor of technical sessions such as WLAN from Basics to Proficiency. Yibo Wang is a documentation engineer of Huawei's campus network WLAN solution. He has nine years of experience in creating documents for campus network products. Mr. Wang was previously in charge of writing manuals for Huawei switches, WLAN products, and routers. He was also a co-sponsor of technical sessions such as WLAN from Basics to Proficiency and HCIA-WLAN certification training courses.
With a pair of magical eyes and tenacity, he is committed to being the best doctor. He is born with a pair of eyes that can clearly see through the human body in the dark. This special ability has made his dream of being a famous doctor. A pair of magical eyes can always find lesions that other doctors cannot see. But because he accidentally discovered the secret of his boss, his life was severely hit. The boss assigned him to work in a very remote place, where there were no family members and friends, and even his girlfriend broke up with him because of that. He was not defeated by setbacks, but strengthened his dream of becoming a famous doctor. His superb medical skills have been noticed by more and more people, and he has since been awarded the title of "the most powerful doctor". ☆About the Author☆ Yu Yang, an outstanding online novelist. His rich life experience has provided inexhaustible motivation for his novel creation, and his novel plot is as good as writing.
The 1949 Communist Revolution marked a period of earthshaking change in China. Political, economic, ideological, and cultural movements galvanized the country, culminating in dramatic social transformations at all levels, including the persecution of hundreds of thousands of the country’s citizens. Based on normally inaccessible records of confessions, interrogations, trial transcripts, and depositions, Eight Outcasts tells the stories of eight victims of the Maoist dictatorship. It introduces readers to individuals accused of infractions such as corruption, political wrong thinking, homosexuality, illicit sexual activity, foreign ties, or “historical problems” (connections to the former Kuomintang regime) in the period between the revolution and Mao’s death in 1976. Each chapter brings stories of China’s voiceless citizens to light, broadening our knowledge of this important transitional period.
A roadmap for easily navigating through the complexities of Chinese herbal medicine, Chinese Herbal Medicine: Modern Applications of Traditional Formulas presents information about herbal formulas in a practical and easy-to-access format. Bridging the gap between classroom study and the clinical setting, the book supplies information on disease sym
Students and practitioners of Chinese herbal medicine must learn hundreds of commonly used herbs as the first step in studying Chinese herbal medicine. Additionally, junior practitioners lack the clinical experience required to ensure that they can skilfully select the appropriate herbs to use in the formulas. This presents them with a major challenge. Chinese Herbal Medicines: Comparisons and Characteristics presents a method of learning individual herbs through vivid and clear discussion of their characteristics and through a comparison with other herbs of their characteristics and strengths. This clear and logical approach makes it easy for the user to understand and memorize the functions of specific herbs. It also enables experienced practitioners to improve their therapeutic results through the use of better formulas. Key features of the new edition - Retains the same easy to follow format as the first edition - Presents detailed comparisons and discussions of commonly used Chinese herbs - Provides a series of thought-provoking questions with very detailed answers - Structured to help the reader to learn and memorize the content more easily - The easy-to-use question-andanswer format is convenient to apply in the consulting room - Includes discussion of clinical applications to help with the practical use of the information in clinical setting - Revised and updated with particular emphasis on the safe use of Chinese herbal medicines - New appendices provide information on safe dosages, commonly used herbal combinations and the meanings of Chinese words used in herbal names - Provides a sound foundation for the study and practice of Chinese herbal medicine. Chinese Herbal Medicinse: Comparisons and Characteristics is already wellknown to students and practitioners of Chinese herbal medicine. This new, improved edition will continue to be of value to students and practitioners alike. It is now supported by a new companion volume by the same author entitled Chinese Herbal Formulas: Treatment Principles and Composition Strategies. Together these two books provide a sound foundation for the study and practice of Chinese herbal medicine. - Detailed and vivid comparisons and discussions of Chinese herbs to help the reader memorize and understand their characteristics - Structured as a series of thought-provoking questions with very detailed answers, again to help memorize the content - Includes "clinical applications" subsection within each section, to help the reader understand how to apply information better and more accurately in the clinical setting.
Stress, Strain, and Structural Dynamics is a comprehensive and definitive reference to statics and dynamics of solids and structures, including mechanics of materials, structural mechanics, elasticity, rigid-body dynamics, vibrations, structural dynamics, and structural controls. This text integrates the development of fundamental theories, formulas and mathematical models with user-friendly interactive computer programs, written in the powerful and popular MATLAB. This unique merger of technical referencing and interactive computing allows instant solution of a variety of engineering problems, and in-depth exploration of the physics of deformation, stress and motion by analysis, simulation, graphics, and animation. This book is ideal for both professionals and students dealing with aerospace, mechanical, and civil engineering, as well as naval architecture, biomechanics, robotics, and mechtronics. For engineers and specialists, the book is a valuable resource and handy design tool in research and development. For engineering students at both undergraduate and graduate levels, the book serves as a useful study guide and powerful learning aid in many courses. And for instructors, the book offers an easy and efficient approach to curriculum development and teaching innovation. - Combines knowledge of solid mechanics--including both statics and dynamics, with relevant mathematical physics and offers a viable solution scheme. - Will help the reader better integrate and understand the physical principles of classical mechanics, the applied mathematics of solid mechanics, and computer methods. - The Matlab programs will allow professional engineers to develop a wider range of complex engineering analytical problems, using closed-solution methods to test against numerical and other open-ended methods. - Allows for solution of higher order problems at earlier engineering level than traditional textbook approaches.
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