In this thesis, Xiaoshi Wang investigates the function and mechanism of a newly discovered heme-thiolate peroxygenase, AaeAPO. This enzyme class comes from Agrocybe aegerita and is used in the conversion of inert hydrocarbons to alcohols. Xiaoshi's work focuses on an extracellular P450 enzyme which is not limited in its stability and lack of solubility and therefore is relevant for widespread industrial use. The author demonstrates that the peroxygenase catalyzes a wide range of reactions. In some cases the author even describes very difficult transformations in molecules that are highly inert. Her detailed investigations provide a mechanistic framework for how the peroxygenase catalyzes such a large number of reactions. A major highlight of this thesis is the identification of key short-lived intermediates in the catalytic cycle of the peroxygenase, using rapid kinetic and spectroscopic methods, as well as the elucidation of the thermodynamic properties of these high-energy intermediates. This work adds new insight into an important class of enzymes.
an imperial edict said that the young miss of the feng family had been married off to the unparalleled beauty of prince jing he had thought that he would be able to run away after completing his goal but now he had fallen into a pit once more your highness you said that you won't touch me a certain woman stepped back that was because you were too young so it wasn't convenient for you prince you are a gentleman if you say something you will not be able to keep up with it yeah so i definitely can't let you go he had clearly said that he would succeed and retreat the female looked at the big tailed wolf that was slowly approaching and wanted to cry but no tears came out
Locality in Grammar: From Narrow Syntax to Interfaces investigates the operation of locality conditions in syntax and semantics from a cross-linguistic perspective. It is claimed that there are two different types of locality conditions. One is the Generalized Minimality Condition (GMC), and the other is the Phase Impenetrability Condition (PIC). This book demonstrates that these locality conditions play different roles in different computational components of human language, and, therefore, cannot be unified as one constraint as proposed in the literature. The main idea of the book is that the two different locality conditions are sensitive to the difference between syntactic derivation and semantic interpretation and that of overt and covert syntactic derivations. Further investigation shows a more fine-grained distinction must be made between syntactic computations. It is true that GMC does not constrain overt syntactic derivations and PIC does not play a role in semantic interpretations; however, they both regulate covert syntactic computations. This book will inform postgraduate students and scholars in the field of linguistics.
This book presents a synthetic analysis about the characteristics of time expressions and named entities, and some proposed methods for leveraging these characteristics to recognize time expressions and named entities from unstructured text. For modeling these two kinds of entities, the authors propose a rule-based method that introduces an abstracted layer between the specific words and the rules, and two learning-based methods that define a new type of tagging scheme based on the constituents of the entities, different from conventional position-based tagging schemes that cause the problem of inconsistent tag assignment. The authors also find that the length-frequency of entities follows a family of power-law distributions. This finding opens a door, complementary to the rank-frequency of words, to understand our communicative system in terms of language use.
an imperial edict said that the young miss of the feng family had been married off to the unparalleled beauty of prince jing he had thought that he would be able to run away after completing his goal but now he had fallen into a pit once more your highness you said that you won't touch me a certain woman stepped back that was because you were too young so it wasn't convenient for you prince you are a gentleman if you say something you will not be able to keep up with it yeah so i definitely can't let you go he had clearly said that he would succeed and retreat the female looked at the big tailed wolf that was slowly approaching and wanted to cry but no tears came out
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