This third edition is the product of the author’s 25 years of experience with flow cytometry; although it covers the wide spectrum of hematopoietic tumors, the focus remains on most important clinical diagnoses, such as acute promyelocytic leukemia, identification of blasts, identification of clonal B-cell population, differentiating mature versus immature T-cell proliferations, deferential diagnosis between hematogones and B-ALL or distinction between chronic and acute monocytic proliferations. All hematopathologists and neoplastic hematologists will find this an important resource for keeping up to date with developments in clinical practice.
This atlas presents not only the differential diagnosis but also the detailed morphologic, immunophenotypic, and especially genetic characteristics of the majority of hematolymphoid malignancies. An expert hematopathologist here provides a valuable resource to understand, use, or interpret one or more of these diagnostic modalities with confidence. This new edition has a compact format with up-to-date information - especially on genetic aspects - and will be an indispensable reference for all professionals in the specialty. *Provides an unrivalled visual resource for differential diagnosis in neoplastic hematopathology *Enables specialist and trainee oncologists and pathologists alike to understand, use, and interpret diagnostic modalities with confidence *Supplies quick access to information via tables, algorithms, and composite figures
Challenging the conventional wisdom that constitutional courts are the best device that democratic systems have for the protection of individual rights, Wojciech Sadurski examines the most recent wave of activist constitutional courts: those that have emerged after the fall of communism in Central and Eastern Europe. In contrast to most other analysts and scholars he does not take for granted that they are a "force for the good", but rather subjects them to critical scrutiny.
This textbook and treatise begins with classical real variables, develops the Lebesgue theory abstractly and for Euclidean space, and analyzes the structure of measures. The authors' vision of modern real analysis is seen in their fascinating historical commentary and perspectives with other fields. There are comprehensive treatments of the role of absolute continuity, the evolution of the Riesz representation theorem to Radon measures and distribution theory, weak convergence of measures and the Dieudonné–Grothendieck theorem, modern differentiation theory, fractals and self-similarity, rearrangements and maximal functions, and surface and Hausdorff measures. There are hundreds of illuminating exercises, and extensive, focused appendices on functional and Fourier analysis. The presentation is ideal for the classroom, self-study, or professional reference.
Management of tumor patients now relies on new individualized approaches to treatment, requiring extensive knowledge of the molecular makeup of tumors. Updated and expanded, the third edition of Atlas of Differential Diagnosis in Neoplastic Hematopathology examines not only the differential diagnosis but also the detailed morphologic, immunophenotypic, and especially genetic characteristics of the majority of hematolymphoid malignancies. Featuring a new structure and including new chapters, the third edition updates all content and presents considerable expansion on many topics, including: Metaphase cytogenetic and FISH Flow cytometry (overview and detailed analysis of specific tumors) Acute myeloid leukemia and new classification schemes MDS, AML, and B- and T-cell lymphoproliferations Abnormal patterns in the lymph node and bone marrow with detail differential diagnosis based on histologic features and cellular composition Detailed differential diagnosis based on the expression of broad list of antigenic markers (flow cytometry and immunohistochemistry) Extranodal lymphomas Diagnosis of MDS and myeloproliferative neoplasm and their differential diagnosis based on the morphologic, flow cytometric, and chromosomal features The book also provides expanded differential diagnosis of the most common as well as most difficult and rare entities, including morphologic, immunophenotypic, and karyotypic/molecular features. This edition includes updated algorithms for most common diagnoses as well as several new algorithms. The majority of figures have been revised and are in full color.
This monograph presents a comprehensive introduction to timed automata (TA) and time Petri nets (TPNs) which belong to the most widely used models of real-time systems. Some of the existing methods of translating time Petri nets to timed automata are presented, with a focus on the translations that correspond to the semantics of time Petri nets, associating clocks with various components of the nets.
This extensive reference covering neoplastic hematopathology includes over 500 colour illustrations depicting hematopoietic tumors involving lymph nodes, spleen, bone marrow, and commonly affected extranodal organs, with special emphasis on the differential diagnosis. It discusses basic clinical, prognostic, morphologic and phenotypic data, with numerous tables summarizing the phenotypic profiles of the most common hematologic tumors. A major feature of this book is an approach to hematologic tumors based on the WHO classification, with relevant examples and emphasis on the most useful morphologic and immunophenotypic features used in diagnosis. It will be an invaluable reference for all practising hematologists, oncologists and pathologists.
The book is devoted to a unification of two major principles of invariance in physics (local gauge and local coordinate invariance) and reducing both principles to the second one in a more than 4-dimensional world. The additional dimensions cannot be directly observed. Thus it is akin to a Kaluza-Klein or Jordan-Thiry point of view. The author develops these ideas using nonriemannian geometry from Einstein's Unified Field Theory. The theory uses nonsymmetric right-invariant metric defined on a principal fibre bundle (a gauge bundle). The book proceeds in three stages: ?Interference effects? between gravity (described by NGT) and gauge field (including electromagnetic field) which appeared due to nonriemannian geometry in the theory and its physical consequences were discovered. Some applications have been pointed out
This volume presents an elaborated version of lecture notes for two advanced courses: (Re)Emerging methods in Commutative Algebra and Representation Theory and Building Bridges Between Algebra and Topology, held at the CRM in the spring of 2015. Homological algebra is a rich and ubiquitous area; it is both an active field of research and a widespread toolbox for many mathematicians. Together, these notes introduce recent applications and interactions of homological methods in commutative algebra, representation theory and topology, narrowing the gap between specialists from different areas wishing to acquaint themselves with a rapidly growing field. The covered topics range from a fresh introduction to the growing area of support theory for triangulated categories to the striking consequences of the formulation in the homotopy theory of classical concepts in commutative algebra. Moreover, they also include a higher categories view of Hall algebras and an introduction to the use of idempotent functors in algebra and topology.
Aimed at graduate students and researchers interested in information theory and the analysis of algorithms, this book explores problems of information and learning theory, demonstrating how to use tools from analytic combinatorics to discover and analyze precise behavior of source codes.
A new approach is presented in this book for modelling multi-body systems, which constitutes a substantial enhancement of the Rigid Finite Element method. The new approach is based on homogeneous transformations and joint coordinates. Apart from its simple physical interpretation and easy computer implementation, the method is also valuable for educational purposes since it impressively illustrates the impact of mechanical features on the mathematical model.
Thermo-ecology: Exergy as a Measure of Sustainability integrates thermo-ecology and exergy replacement cost as a new and original tool called thermo-ecology cost, or TEC. This tool allows for a more inclusive measurement of the impacts of using renewable and non-renewable resources by including the thermodynamics law in decision-making and presenting applications of this tool across industries and lifecycle assessments. It includes ways to investigate these effects more effectively by combining these critical aspects. This combination has emerged as a valuable decision-support tool for policymakers and the industry as they seek to evaluate the impacts of a product or process. - Walks through what Thermo-Ecology Cost (TEC) is and why it gives a more holistic assessment when calculating the costs vs benefits of utilizing a natural resource - Provides a new and more efficient way to measure and evaluate the sustainability of resources - Includes: TEC calculation examples to explain the TEC theory as well as to help readers prepare their own analyses devoted to exergo-ecological applications across industries including energy production and waste management - Demonstrates the potential of TEC usage for applications like ecological taxes proportional on TEC
How have national identities changed, developed and reacted in the wake of transition from communism to democracy in Central and Eastern Europe? Central and Eastern Europe After Transition defines and examines new autonomous differences adopted at the state and the supranational level in the post-transitional phase of the post-Communist area, and considers their impact on constitutions, democracy and legal culture. With representative contributions from older and newer EU members, the book provides a broad set of cultural points for reference. Its comparative and interdisciplinary approach includes a useful selection of bibliographical resources specifically devoted to the Central Eastern European countries' transitions.
Praxiology deals with doing and working from the point of view of effectiveness. It has three components: analysis of concepts involving purposive actions; critique of models of action from the viewpoint of efficiency; and normative advisory aspects in recommendations for increasing human efficiency. This fourth volume of the Praxiology series is devoted to the very special topic of social agency. It focuses on two important praxiological concepts: rationality and preparation as preconditions for human action to be effective and efficient. The question of efficiency was raised by Anatol Rapoport over three decades ago in his lecture to the audience at the Praxiological Seminar in Warsaw in 1961. Social Agency begins with an article written by this same famous scholar on the topic of decision theory, "Social Dilemmas: A Historical Overview." Social dilemmas is the subject of the first part of this volume, a question related to studies on human action guided by two types of rationality: individual and collective rationality. The intersection of the two, in which individuals meet collectives, creates the situation in which social agency emerges, generating dilemmatic circumstances for the actors involved. The articles collected in the second part explore praxiological dimensions of education aimed toward the knowledge society, because of knowledge possessed and produced by educated persons. Chapters and contributors to volume 4 include: "Five Questions on the Research on Social Dilemmas" by Marek K. Mlicki; "Psychological Processes Underlying Cooperation in Social Dilemmas" by Paul A. M. Van Lange and David M. Messick; "Designing a System for Design Learning: Designers and/or Learners?" by Arne Collen; "Creating an Evolutionary Image of New Systems of Learning and Human Development" by Janet A. Khan; and "A Study Program Design in Retrospect" by Stig C. Holmberg. Social Agency continues the trend of original research done in a little-known, but important area. Social scientists, policymakers, and educators will benefit from this work.
The 1914–2024 War Atlas deconstructs the contemporary widespread and well-known image of the 20th and 21st centuries, arguing for the continuity of the historical process covering the period 1914–2024. The years between 1914 and 2024 constitute a period of unparalleled economic growth, scientific advancement, political development, and social change – in just over 100 years, human civilization has moved from an industrial to a digital age. However, they also cover some of the most dangerous, violent, and politically volatile years in human history. In these years, two world wars have been fought; weapons of mass destruction dropped; authoritarian and democratic regimes alike have risen and fallen; and regional conflicts have been almost continuous, effectively conjoining World War I, World War II, the Cold War, and the Russo-Ukrainian war. This volume indicates that the 1914 July Crisis set in motion a sequence of events that spanned over 100 years. Containing a range of colourful maps and charts, this book graphically illustrates the arguments presented in both an informative and visual way. This atlas will serve as a perfect textbook for students studying history, geography, politics, and international relations, as well as being a useful guide to contemporary world politics for researchers and for those interested in international relations and modern history.
Computational Analysis of Structured Media presents a systematical approach to analytical formulae for the effective properties of deterministic and random composites. Schwarz's method and functional equations yield for use in symbolic-numeric computations relevant to the effective properties. The work is primarily concerned with constructive topics of boundary value problems, complex analysis, and their applications to composites. Symbolic-numerical computations are widely used to deduce new formulae interesting for applied mathematicians and engineers. The main line of presentation is the investigation of two-phase 2D composites with non-overlapping inclusions randomly embedded in matrices. - Computational methodology for main classes of problems in structured media - Theory of Representative Volume Element - Combines exact results, Monte-Carlo simulations and Resummation techniques under one umbrella - Contains new analytical formulae obtained in the last ten years and it combines different asymptotic methods with the corresponding computer implementations
This book constitutes the refereed proceedings of the 21st International Symposium on Mathematical Foundations of Computer Science, MFCS '96, held in Crakow, Poland in September 1996. The volume presents 35 revised full papers selected from a total of 95 submissions together with 8 invited papers and 2 abstracts of invited talks. The papers included cover issues from the whole area of theoretical computer science, with a certain emphasis on mathematical and logical foundations. The 10 invited presentations are of particular value.
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