This 1998 book describes the sampling and statistical methods used most often by behavioral ecologists and field biologists. Written by a biologist and two statisticians, it provides a rigorous discussion together with worked examples of statistical concepts and methods that are generally not covered in introductory courses, and which are consequently poorly understood and applied by field biologists. The first section reviews important issues such as defining the statistical population and the sampling plan when using non-random methods for sample selection, bias, interpretation of statistical tests, confidence intervals and multiple comparisons. After a detailed discussion of sampling methods and multiple regression, subsequent chapters discuss specialized problems such as pseudoreplication, and their solutions. It will quickly become the statistical handbook for all field biologists.
Since publication of the First Edition in 1982, Hemostasis and Thrombosis has established itself as the pre-eminent book in the field of coagulation disorders. No other book is as inclusive in scope, with coverage of the field from the standpoint of both basic scientists and clinicians. This comprehensive resource details the essentials of bleeding and thrombotic disorders and the management of patients with these and related problems, and delivers the most up-to-date information on normal biochemistry and function of platelets or endothelial cells, as well as in-depth discussions of the pharmacology of anticoagulant, fibrinolytic, and hemostatic drugs. NEW to the Sixth Edition... • A new team of editors, each a leader in his field, assures you of fresh, authoritative perspectives. • Full color throughout • A companion website that offers full text online and an image bank. • A new introductory section of chapters on basic sciences as related to the field • Entirely new section on Hemostatic and Thrombotic Disorders Associated with Systemic Conditions includes material on pediatric patients, women's health issues, cancer, sickle cell disease, and other groups. • Overview chapters preceding each section address broad topics of general importance. This is the tablet version which does not include access to the supplemental content mentioned in the text.
A book that finally demystifies Newton’s experiments in alchemy When Isaac Newton’s alchemical papers surfaced at a Sotheby’s auction in 1936, the quantity and seeming incoherence of the manuscripts were shocking. No longer the exemplar of Enlightenment rationality, the legendary physicist suddenly became “the last of the magicians.” Newton the Alchemist unlocks the secrets of Newton’s alchemical quest, providing a radically new understanding of the uncommon genius who probed nature at its deepest levels in pursuit of empirical knowledge. In this evocative and superbly written book, William Newman blends in-depth analysis of newly available texts with laboratory replications of Newton’s actual experiments in alchemy. He does not justify Newton’s alchemical research as part of a religious search for God in the physical world, nor does he argue that Newton studied alchemy to learn about gravitational attraction. Newman traces the evolution of Newton’s alchemical ideas and practices over a span of more than three decades, showing how they proved fruitful in diverse scientific fields. A precise experimenter in the realm of “chymistry,” Newton put the riddles of alchemy to the test in his lab. He also used ideas drawn from the alchemical texts to great effect in his optical experimentation. In his hands, alchemy was a tool for attaining the material benefits associated with the philosopher’s stone and an instrument for acquiring scientific knowledge of the most sophisticated kind. Newton the Alchemist provides rare insights into a man who was neither Enlightenment rationalist nor irrational magus, but rather an alchemist who sought through experiment and empiricism to alter nature at its very heart.
This book summarizes 20 years of work on the kinetics of blood-brain transfer and metabolism mechanisms in mammalian brain. The substances affiliated with these mechanisms include glucose, amino acids, monocarboxylic acids, and oxygen. These substances are important to energy metabolism and neurotransmission in the mammalian brain at rest and during activation. To understand the processes addressed by these mechanisms, the book examines the kinetics of compartmentation and compartmental analysis, particularly as they relate to transporter, enzyme, and receptor function. Compartments are subsets of substances separated by transporters and receptors in membranes, and enzymes in cells. This book is divided in six major chapters covering compartmental analysis, kinetic analysis of transport and metabolism, blood-brain transfer and metabolism of glucose, amino acids, and oxygen, and amino acid metabolism and interaction of amino acid metabolites with receptors.
Effectively manage the chronic problems of your hypertensive patients with the practical clinical tools inside Hypertension, 2nd Edition: A Companion to Braunwald’s Heart Disease. This respected cardiology reference covers everything you need to know - from epidemiology and pathophysiology through diagnosis, risk stratification, treatment, outcome studies, concomitant diseases, special populations and special situations, and future treatments. Confidently meet the needs of special populations with chronic hypertensive disease, as well as hypertension and concomitant disease. Learn new methods of aggressive patient management and disease prevention to help ensure minimal risk of further cardiovascular problems. Benefit from the authors’ Clinical Pearls to reduce complications of hypertension. Use new combination drug therapies and other forms of treatment to their greatest advantage in the management of chronic complications of hypertension. Successfully employ behavior management as a vital part of the treatment plan for hypertensives and pre-hypertensives.
In Night Hunters, air power historian William P. Head provides the first detailed study of the development and deployment of the AC-130 gunship. While other airframes and other types of close air support (CAS) and interdiction weapon systems preceded or flew with the AC-130s, this four-engine cargo airframe proved to be not only the longest serving fixed-wing gunship but also the most effective by far. During the Vietnam War, the US military developed new tactics and weapons systems to counter a diversity of enemy tactics and geographic features, the difficult climate, and the shifting diplomatic context. One of the most important was the development of the AC-130. Its ability to transport heavier payloads at higher altitudes across longer distances made it the logical choice to be the final Vietnam-era fixed-wing gunship and the only one that continues to fly missions in the twenty-first century. In addition, it employed many of the most advanced weapons, sensors, targeting devices, and fire control systems of the 1970s or of any era. By recounting both the technical development and the combat operations of the plane, and by looking at the proposed alternatives for its use in the War on Terror, Night Hunters offers a clear view of the role of gunships and of close air support in US wars. In today’s never-ending brushfire wars, the AC-130s continue to uphold their reputation for excellence.
Resistance arteries have been recognized for some time as key factors in the regulation of vascular flow resistance, where they determine the regional and local distribution of blood and arterial pressure. Chapters provide an overview of the physiological, biochemical, and electrophysiological characteristics of these vessels, as well as a critical evaluation of the methodologies for studying small arteries and an examination of the membrane and neural mechanisms involved in the control of vascular tone.
All veterinary team members involved in the everyday care of horses that require anesthesia or special emergency care will benefit from this reliable and inclusive resource. This text provides all of the information needed to prepare, conduct, and monitor the administration of drugs in order to produce safe and effective anesthesia, treat pain, respond to adverse effects, and perform and monitor emergency and critical care treatment. It is the most comprehensive and detailed book available on these subjects, addressing the needs and concerns of practitioners in both hospital and field settings. Discusses all aspects of equine anesthesia, including history, physiology, pharmacology, drug dosages, patient preparation, induction-maintenance-recovery of anesthesia management of potential complications, and more. Provides a detailed review of the respiratory and cardiovascular physiology of the horse. Provides thorough coverage of preoperative pain management in horses. Covers emergency medical care and managing anesthetic complications in both hospital and field situations. Includes information on the latest anesthetic drugs, including safe and effective protocols for different procedures, and the most up-to-date monitoring techniques. Each contributor is a recognized expert in his or her respective equine specialty, renowned for clinical as well as academic and research expertise. A complete update of all drug information and pain management techniques. The very latest research findings and clinical applications of anesthetic agents and techniques. The most recent developments in post-anesthetic care and monitoring. A chapter on intravenous anesthetic and analgesic adjuncts to inhalation anesthesia. A chapter on anesthesia and analgesia for donkeys and mules. A chapter on perioperative pain management. Many new illustrations as well as tables, graphs, boxes, key points, and summaries that make information instantly accessible.
Cerebrovascular disease results in huge health expenditures, multiple recurring physician visits, and a great number of surgical and non-surgical treatments along with research into causes and prevention. This issue addresses therapies, early therapies, diagnoses, and prevention. Topics include: Endovascular Treatment of Acute Ischemic Stroke; Acute Treatment of Blood Pressure after Ischemic Stroke and Intracerebral Hemorrhage; Diagnostic Evaluation for Non-traumatic Intracerebral Hemorrhage; Prevention of Recurrent Stroke in Patients with Patent Foramen Ovale; Management of Asymptomatic Carotid Stenosis; Stenting or Endarterectomy for Patients with Symptomatic Carotid Stenosis; The Therapeutic Value of Laboratory Testing for Hypercoagulable States in Secondary Stroke Prevention; Diagnosis and Treatment of Carotid and Vertebral Artery Dissection; Recurrent Stroke while on Anti-platelet Therapy; Anti-platelet and Anti-coagulant Therapy after Intracerebral Hemorrhage; Diagnosis and Treatment of Isolated Central Nervous System Angiitis/Vasculitis; Statins for Aneurysmal Subarachnoid Hemorrhage; Expansion of IV-tPA eligibility beyond NINDS and ECASS III criteria; and Treatment of Unruptured Arteriovenous Malformations. William J Powers MD, renowned for his clinical work with Stroke and Research in Cerebral blood flow and metabolism, and stroke treatment and prevention, leads this issue of Neurologic Clinics, with authors renown in the field.
Experimental findings have indicated an association between well-child care and cost-efficient health care and increased school readiness. But insurance companies and Medicaid administrators sometimes arent aware of the findings, which is why a book on well-child care is so necessary. William Pittard, a longtime medical doctor who has spent decades specializing in pediatrics, teams up with other experts to explore how well-child care promotes the health and future success of children in this book for parents, health care providers, policy makers, and others. Learn how: Medicaids scope has been broadened to include preventative care; confrontations and controversies have led to health care reform; legislators and others can take action to improve coverage. The preventive care the authors focus on includes anticipatory guidance; continuity of care; assessment of growth and development; screening procedures for vision, hearing, dental, and cognitive development; and immunizations. By learning more about the health care system and what the latest research tells us about well-child care, youll be better equipped to promote the health and future success of children in a cost-effective way. Thats a win for parents, insurance companies, taxpayers, and most importantlythe next generation.
From fundamental principles to advanced subspecialty procedures, Miller’s Anesthesia covers the full scope of contemporary anesthesia practice. This go-to medical reference book offers masterful guidance on the technical, scientific, and clinical challenges you face each day, in addition to providing the most up-to-date information available for effective board preparation. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Address the unique needs of pediatric patients with guidance from an entire section on pediatric anesthesia. View more than 1,500 full-color illustrations for enhanced visual clarity. Access step-by-step instructions for patient management, as well as an in-depth analysis of ancillary responsibilities and problems. Quickly reference important concepts with ‘Key Points’ boxes integrated into every chapter. Stay current on today's most recent anesthetic drugs and guidelines/protocols for anesthetic practice and patient safety, and access expanded coverage on new techniques such as TEE and other monitoring procedures. Take advantage of the unique, international perspectives of prominent anesthesiologists from all over the world, including the UK, Australia, India, Brazil, and Germany. Remain at the forefront of new developments in anesthesia with coverage of hot topics including Non-OR Anesthesia; Role of the Anesthesiologist in Disasters; Sleep Medicine in Anesthesia; Perioperative and Anesthesia-related Neurotoxicity; Anesthetic Implications of Complementary and Alternative Medicine; and Robotics. Study brand-new chapters on Perioperative Fluid Management; Extracorporeal Support Therapies; Anesthesia for Organ Donation/Procurement; and Malignant Hyperthermia and other Genetic Disorders.
Now in striking full color, this Seventh Edition of Koneman’s gold standard text presents all the principles and practices readers need for a solid grounding in all aspects of clinical microbiology—bacteriology, mycology, parasitology, and virology. Comprehensive, easy-to-understand, and filled with high quality images, the book covers cell and structure identification in more depth than any other book available. This fully updated Seventh Edition is enhanced by new pedagogy, new clinical scenarios, new photos and illustrations, and all-new instructor and student resources.
This work indexes all extant, no-Shakespearean drama in English from Henry Medwall's "Nature" to plays first performed in the year of Shakespeare's death.
Four hundred seventy years ago the Anabaptist movement was launched with the inauguration of believer's baptism and the formation of the first congregation of the Swiss Brethren in Zurich, Switzerland. This standard introduction to the history of Anabaptism by noted church historian William R. Estep offers a vivid chronicle of the rise and spread of teachings and heritage of this important stream in Christianity. This third edition of The Anabaptist Story has been substantially revised and enlarged to take into account the numerous Anabaptist sources that have come to light in the last half-century as well as the significant number of monographs and other scholarly works on Anabaptist themes that have recently appeared. Estep challenges a number of assumptions held by contemporary historians and offers fresh insights into the Anabaptist movement.
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