This manual provides an educationally focused and practically applicable resource for trainee dermatologists undertaking various dermatology board examinations. Concise, easy-to-follow chapters featuring relevant videos with editorial commentary aid the reader in developing an in depth understanding of a range of skin conditions and their management. Key concepts relevant to cutaneous neoplasms, fungal infections, dermatopharmacology, chemical peels, disorders of pigmentation and dermatopathology are all covered. Emphasis is placed on breaking topics down into modules, similar to that now taken by many dermatology board assessments for trainee dermatologists, aiding the reader easily access the content they need. Clinical Manual of Dermatology concisely describes many key concepts required to gain a thorough understanding of a range of topics in dermatology crucial to successfully completing dermatology board examinations. It is therefore, a valuable resource for all trainee dermatologists.
Groundwater Geochemistry: Fundamentals and Applications to Contamination examines the integral role geochemistry play s in groundwater monitoring and remediation programs, and presents it at a level understandable to a wide audience. Readers of all backgrounds can gain a better understanding of geochemical processes and how they apply to groundwater systems. The text begins with an explanation of fundamental geochemical processes, followed by a description of the methods and tools used to understand and simulate them. The book then explains how geochemistry applies to contaminant mobility, discusses remediation system design, sampling program development, and the modeling of geochemical interactions. This clearly written guide concludes with specific applications of geochemistry to contaminated sites. This is an ideal choice for readers who do not have an extensive technical background in aqueous chemistry, geochemistry, or geochemical modeling. The only prerequisite is a desire to better understand natural processes through groundwater geochemistry.
Dr. Richard Polin's Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. - Stay fully up to date in this fast-changing field with Nephrology and Fluid/Electrolyte Physiology, 3rd Edition. - New chapters on Inherited Disorders of Calcium, Phosphate and Magnesium; Fluid and Electrolyte Management of High Risk Infants; Renal Development and Molecular Pathogenesis of Renal Dysplasia; and Prenatal Programming, which describes how prenatal insults can result in hypertension, kidney and cardiovascular disease. - The most current clinical information, including new content on the molecular basis for hereditary tubulopathies and inherited disorders of calcium, phosphate, and magnesium homeostasis. - New information on genetics and pharmacology, neonatal hypertension, diuretic use in the newborn, prenatal programming of adult diseases, lung fluid balance, and much more. - Consistent chapter organization to help you find information quickly and easily. - The most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume set!Gastroenterology and NutritionHematology, Immunology and GeneticsHemodynamics and CardiologyInfectious Disease and Pharmacology New Volume!Nephrology and Fluid/Electrolyte PhysiologyNeurologyThe Newborn Lung
Offers a compendium of information on retrosynthesis and process chemistry, featuring innovative "reaction maps" showing synthetic routes of some widely used drugs This book illustrates how the retrosynthetic tool is applied in the Pharmaceutical Industry. It considers and evaluates the many viable synthetic routes that can be used by practicing industrialists, guiding readers through the various steps that lead to the "best" processes and the limits encountered if these are put into practice on an industrial scale of seven key Active Pharmaceutical Ingredient (API). It presents an evaluation of the potential each process has for implementation, before merging the two points of view—of retrosynthesis and process chemistry—in order to show how retrosynthetic analysis assists in selecting the most efficient route for an industrial synthesis of a particular compound whilst giving insight into the industrial process. The book also uses some key concepts used by process chemists to improve efficiency to indicate the best route to select. Each chapter in Retrosynthesis in the Manufacture of Generic Drugs Selected Case Studies is dedicated to one drug, with each containing information on: worldwide sales and patent status of the Active Pharmaceutical Ingredient (API); structure analysis and general retrosynthetic strategy of the API; first reported synthesis; critical analysis of the processes which have been developed and comparison of the synthetic routes; lessons learned; reaction conditions for Schemes A to X; chemical "highlights" on key reactions used during the synthesis; and references. Drugs covered include: Gabapentin, Clopidogrel, Citalopram and Escitalopram, Sitagliptin, Ezetimibe, Montelukast, and Oseltamivir. Show how the retrosynthetic tool is used by the Pharmaceutical Industry Fills a gap for a book where retrosynthetic analysis is systematically applied to active pharmaceutical ingredients (APIs) Features analyses and methodologies that aid readers in uncovering practical synthetic routes to other drug substances, whether they be NCEs (New Chemical Entities) or generic APIs (Active Pharmaceutical Ingredients) Presents information from both the patent and academic literature for those who wish to use as a basis for further study and thought Features the use of "reaction maps" which display several synthetic processes in the same scheme, and which allow easy comparisons of different routes that give the same molecule or intermediate. A selection of these maps are available to download from: https://www.wiley.com/go/santos/retrosynthesis Retrosynthesis in the Manufacture of Generic Drugs Selected Case Studies is an ideal book for researchers and advanced students in organic synthetic chemistry and process chemistry. It will also be of great benefit to practitioners in the pharmaceutical industry, particularly new starters, and those new to process chemistry.
Containing 100 challenging clinical cases illustrated with superb, high-quality images, this book covers a wide range of dermatological conditions, from the commonly occurring to those slightly rarer cases. This book is an invaluable reference for all dermatology professionals in practice and offers the perfect revision guide for those in training, from hospital-based doctors preparing for higher examinations to established physicians in their continuing professional development.
The COVID-19 Textbook: Science, Medicine, and Public Health explores every facet of SARS-COV-2, giving the reader an understanding of what is needed to control the spread of the virus, prevent and manage its pathological effects, as well as mitigate the impact of future pandemics. Each chapter is authored by leading global experts in the field and includes topics such as molecular biology, epidemiology, pathogenesis, immunology, diagnosis, and the latest prevention and treatment approaches. Edited by renowned educator and medical researcher Dr. William A. Haseltine, physician-researcher, and chronic fatigue syndrome expert Dr. Roberto Patarca, it includes detailed references in every chapter, allowing easy access to comprehensive primary data. • Offers a timely, reliable overview authored and edited by leading global experts in the multifaceted areas covered on SARS-CoV-2 and the COVID-19 pandemic. • Serves as an authoritative and comprehensive text to be utilized by physicians, medical professionals, researchers, students, public health professionals, and policymakers.
Widely recognized as the gold standard reference in the field, Green's Operative Hand Surgery, 8th Edition, provides complete coverage of the surgical and nonsurgical management of the full range of upper extremity conditions. In a clearly written and well-illustrated format, it contains both foundational content for residents and fellows as well as new approaches, case-based controversies, and outcomes-based solutions for practitioners. Drs. Scott W. Wolfe, William C. Pederson, Scott H. Kozin, and Mark S Cohen, along with new, international contributing authors, provide expert perspectives and preferred methods for all aspects of today's hand, wrist, and elbow surgery. - Contains thoroughly revised and updated indications and techniques to treat the full spectrum of upper extremity disorders. - Highlights the latest advances and approaches, such as wide-awake local anesthesia no tourniquet (WALANT) hand surgery, nerve transfer techniques, tendon transfer and tendon avulsion repairs, skin grafting techniques, and more. - Offers nearly 140 innovative and high-resolution videos (99 are NEW) that provide real-life, step-by-step guidance on key procedures. - Provides state-of-the-art information on wrist arthritis, hand trauma, new arthroplasties, targeted muscle reinnervation, wrist instability surgeries, fracture management, rehabilitation, congenital disorders, orthotic interventions, and more. - Includes newly updated, high-resolution illustrations, images, and photos throughout. - Presents case-based controversies and unique solutions, plus current views on what works and what does not, based on recent science and outcome measures. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
A concise, yet comprehensive source of current information on the medical problems of children –-- from birth through adolescence A Doody’s Core Title for 2019! •A practical, up-to-date well-referenced guide to the diagnosis and treatment of the most commonly seen medical conditions in children •Excellent coverage of The Council on Medical Student Education in Pediatrics (COMSEP) curriculum used in pediatric clerkship •46 chapters cover a wide range of topics, including neonatal medicine, child development and behavior, emergency and critical care medicine, and diagnosis and treatment of specific disorders according to major problems, etiologies, and organ systems •A wealth of tables and figures provide quick access to important information, such as acute and critical care procedures in the delivery room, the office, the emergency room, and the critical care unit; anti-infective agents, drug dosages, immunization schedules, differential diagnoses, and developmental disorders •Includes detailed descriptions of diseases as well as diagnostic and therapeutic procedures •Complete with handy guide to normal laboratory values •Presented in the consistent, easy-to-follow CURRENT format •Valuable to medical students, pediatric residents, pediatricians, family practitioners, nurses, nurse practitioners, physician assistants, and other healthcare providers who work with infants, children, and adolescents •Authors are practicing pediatricians to ensure that each chapter reflects the needs and realities of day-to-day practice
The most practical, up-to-date, and well-referenced guide to the diagnosis and treatment of children—from birth to adolescence A Doody's Core Title for 2021! Following the "Current" outline format to make it super easy for you to find the answers you need, this comprehensive, clinically focused guide delivers evidence-based information on the pediatric medical conditions most often encountered in daily clinical practice. Complete with an invaluable guide to normal laboratory values and 600 photos and illustrations, CURRENT Diagnosis and Treatment Pediatrics offers succinct, authoritative overviews of important pediatric health concerns, such as childhood nutrition and eating disorders; substance abuse; psychiatric disorders; child abuse; oral medicine and dentistry; immunization; and emergencies and injuries. The authors provide detailed descriptions of diseases as well as diagnostic and therapeutic procedures, and everything is presented in the time-saving LANGE CURRENT style: Problem, Essentials of Diagnosis, Clinical Findings, Differential Diagnosis, Treatment, and Prognosis.
Offering a thorough, accessible overview of the basic science and clinical data regarding the virus that causes COVID-19, Molecular Biology of SARS-CoV-2 is an excellent resource for researchers, clinical scientists, physicians, and students. This volume offers in-depth, extended content that originated with Drs. Roberto Patarca’s and William A. Haseltine’s chapter in The COVID-19 Textbook, edited by Dr. Haseltine and Dr. Patarca. The greatly expanded material in this text provides a much-needed primer in this complex area.
This book introduces graduate students in physics, optics, materials science and electrical engineering to surface plasmons, and applications of surface plasmon physics.
Provides a thorough and up-to-date overview of radiogenic and stable isotope geochemistry Now in its second edition, Isotope Geochemistry presents a comprehensive introduction to radiogenic and stable isotope geochemistry. The book opens with an overview of the physics and origins of atoms and nuclei, followed by a review of radioactive decay schemes and geochronological techniques such as fission-track and carbon-14 dating. Subsequent chapters cover nucleosynthetic anomalies in meteorites, early solar system chronology, the theory and application of stable isotope geochemistry, isotopic variation in the noble gases, and more. This edition includes new sections on thermochronology, U-He dating, recently published La–Ce isotope data, stable isotopes in ore deposits, nuclear volume and nuclear spin effects, and the application of isotope geochemistry in areas such as agriculture, forensics, and environmental studies. Revised and expanded discussions address topics including isotope cosmochemistry, non-traditional isotopes, nucleosynthesis, advanced U-Pb dating and isotopic analysis technologies, the subcontinental lithosphere, and mass-independent isotope fractionation. Describes the use of radiogenic isotopes in understanding the evolution of the Earth’s mantle, crust, and oceans Explores the use of stable isotopes in areas such as mantle evolution, archeology, paleontology, ore formation, and paleoclimatology Reviews new developments in the understanding of nucleosynthesis, including insights gained from the study of the 2017 neutron star merger detected by gravitational waves Discusses progress in the field of unconventional isotopes, advances in isotope cosmochemistry, and recent data on regional variations in isotopic compositions Illustrated in full color throughout, Isotope Geochemistry, Second Edition is an excellent textbook for undergraduate and postgraduate students in all earth science disciplines.
Soil and Environmental Chemistry, Second Edition, presents key aspects of soil chemistry in environmental science, including dose responses, risk characterization, and practical applications of calculations using spreadsheets. The book offers a holistic, practical approach to the application of environmental chemistry to soil science and is designed to equip the reader with the chemistry knowledge and problem-solving skills necessary to validate and interpret data. This updated edition features significantly revised chapters, averaging almost a 50% revision overall, including some reordering of chapters. All new problem sets and solutions are found at the end of each chapter, and linked to a companion site that reflects advances in the field, including expanded coverage of such topics as sample collection, soil moisture, soil carbon cycle models, water chemistry simulation, alkalinity, and redox reactions. There is also additional pedagogy, including key term and real-world scenarios. This book is a must-have reference for researchers and practitioners in environmental and soil sciences, as well as intermediate and advanced students in soil science and/or environmental chemistry. - Includes additional pedagogy, such as key terms and real-world scenarios - Supplemented by over 100 spreadsheets to migrate readers from calculator-based to spreadsheet-based problem-solving that are directly linked from the text - Includes example problems and solutions to enhance understanding - Significantly revised chapters link to a companion site that reflects advances in the field, including expanded coverage of such topics as sample collection, soil moisture, soil carbon cycle models, water chemistry simulation, alkalinity, and redox reactions
The most comprehensive textbook available on therapeutic modalities in rehabilitation—enhanced by a full-color presentation and numerous case studies This practically oriented guide presents the basic science and current best available evidence for each type of therapeutic modality used in physical rehabilitation. Here, clinicians will find the information needed to determine which modality will be most effective in a given situation to achieve optimal patient outcomes. Each chapter examines the physiologic basis for use, clinical applications, specific techniques of application through the use of related laboratory activities, and relevant individual case studies for each therapeutic modality. Therapeutic Modalities in Rehabilitation, Sixth Edition is divided into six parts: Part 1: Foundations of Therapeutic Modalities examines the scientific basis for using therapeutic modalities, classifies the modalities according to the type of energy each uses, and includes guidelines for selecting the most appropriate modalities for managing pain and for use in different phases of the healing process. Part II: Electrical Energy Modalities discusses the principles of electricity, components of electrical and electrotherapeutic currents, treatment parameters, physiological responses to electrical current, iontophoresis, and biofeedback. Part III: Thermal Energy Modalities focuses on modalities which produce a change in tissue temperatures through conduction and convection including thermotherapy and cryotherapy. Part IV: Sound Energy Modalities covers modalities that utilize acoustic energy to produce a therapeutic effect, including therapeutic ultrasound and extracorporeal shockwave therapy. Biologic effects and clinical applications are also discussed. Part V: Electromagnetic Energy Modalities examines diathermy, as well as photobiomodulation (light therapy) treatment techniques and protocols. Part VI: Mechanical Energy Modalities includes chapters on traction, intermittent pneumatic compression, therapeutic massage and vibration. Presented in full color, the text is enhanced by valuable learning aids, including chapter objectives and summaries, figures and tables, clinical decision-making exercises, review questions, instructional videos, a glossary of key terms in each chapter, up-to-date references, case studies, lab activities, and appendices.
The world's most comprehensive, well documented, and well illustrated book on this subject. With extensive subject and geographic index. 80 photographs and illustrations - many color. Free of charge in digital PDF format.
The world's most comprehensive, well documented, and well illustrated book on this subject. With extensive index. 372 photographs and illustrations. Free of charge in digital format on Google Books.
The 2002 Workshop on Frontiers in Electronics was the third in the series of WOFE workshops. Over 70 leading experts from academia, industry, and government agencies reported on the most recent developments in their fields and exchanged views on future trends and directions of the electronics and photonics industry. The issues they addressed ranged from system-on-chip to DNA doping, from ultrathin SOI to electrotextiles, from photonics integration on the ULSI platform to wide band gap semiconductor devices and solid state lighting. The rapid pace of electronic technology evolution compels a merger of different technical areas, and WOFE-02 provided a unique opportunity for cross-fertilization of the emerging fields of microelectronics, photonics, and nanoelectronics. The workshop was informal and stimulated provocative views, visionary outlooks, and discussions on controversial issues. Contents: Optical Wave Propagation in Periodic Structures (A Yariv & S Mookherjea); MEMS Technology for Advanced Telecommunication Applications (H-G Lee et al.); Low Temperature Physics at Room Temperature in Water: Charge Inversion in Chemical and Biological Systems (A Yu Grosberg et al.); Materials for Strained Silicon Devices (P M Mooney); System-on-Chip Integration (R R Doering); Nanoelectronics: Some Current Aspects and Prospects (R Hull et al.); Electrotextiles (E Ethridge & D Urban); System Impact of Silicon Carbide Power Devices (B Ozpineci et al.); Hot-Phonon Limited Electron Energy Relaxation in AIN/GaN (A Matulionis et al.); Polar-Optical Phonon Enhancement of Harmonic Generation in Schottky Diodes (B Gelmont et al.); Environmental Sensing of Chemical and Biological Warfare Agents in the THz Region (A C Samuels et al.); Thermal Management in Optoelectronics (D K Johnstone); Spectral Response Measurements of Short Wave Infrared Detectors (SWIR) (T F Refaat et al.); Full-Chip Power-Supply Noise: The Effect of On-Chip Power-Rail Inductance (C W Fok & D L Pulfrey); Quantum Dot Superlattices in a Constant Electric Field: Localization and Bloch Oscillations (R A Suris & I A Dmitriev); and other papers. Readership: Scientists, engineers and graduate students working in the area of microelectronics, semiconductor materials and devices.
Since its discovery in 1854, chlorosulfonic acid has demonstrated that it is a truly versatile reagent. It is widely used as a sulfonating and chlorosulfonating agent, particularly of organic compounds, and it provides useful synthetic intermediates for many branches of industry. This book provides a detailed, up to date account of the reactions of chlorosulfonic acid with aliphatic, aromatic and heterocyclic compounds; reactions with elements and inorganic compounds are also discussed, along with the use of the reagent as a powerful acid catalyst, and halogenation and dehydrating agent. Finally, the commercial uses and manufacture of chlorosulfonic acid are reviewed. The detailed coverage in this book, coupled with the many references to recent work, will ensure that it is welcomed as a reference by synthetic chemists in, for example, the pharmaceutical, agrochemical, plastic and detergent industries. Researchers and their students in academia will also find it a valuable addition to their bookshelves.
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