In this fifth edition of Principles of Exercise Testing and Interpretation, as in earlier editions, we attempt to develop conceptual advances in the physiology and pathophysiology of exercise, particularly as related to the practice of medicine. The underlying theme of the book continues to be the recognition that the most important requirement for exercise performance is transport of oxygen to support the bioenergetic processes in the muscle cells (including, of course, the heart) and elimination of the carbon dioxide formed as a byproduct of exercise metabolism. Thus, appropriate cardiovascular and ven- tilatory responses are required to match those of muscle respiration in meeting the energy demands of exercise. As depicted by the logo on the book cover, normal exercise performance requires an efficient coupling of external to internal (cellular) respiration. Appropriate treatment of exercise intolerance requires that patients' symptoms be thought of in terms of a gas exchange defect between the cell and the environment. The defect may be in the lungs, heart, peripheral or pulmonary circulations, the muscles themselves, or there may be a combination of defects. Thus, we describe the pathophysiology in gas transport and exchange that affect any site in the cardio- respiratory coupling between the lungs and the muscles. We illustrate how cardiopulmonary exercise testing can provide the means for a critical evaluation by the clinician-scientist of the functional competency of each component in the coupling of cellular to external respiration, including the cardiovascular system. To achieve this, clinical cases are used to illustrate the wide spectrum of pathophysiology capable of causing exercise intolerance"--Provided by publisher.
Thoroughly revised and updated for today’s clinicians, Wasserman & Whipp’s Principles of Exercise Testing and Interpretation, Sixth Edition, provides a comprehensive, practical overview of cardiopulmonary exercise testing (CPET) ideally suited for pulmonologists, cardiologists, anesthesiologists, and others with an interest in clinical exercise testing. Written by authors who are uniquely positioned to convey relevant aspects of research and apply them to clinical contexts, this volume offers in-depth coverage of essential information for conducting CPET, or for utilizing data from this discipline in clinical practice or research.
This book provides a penetrating and comprehensive description of energy selected reactions from a theoretical as well as experimental view. Three major aspects of unimolecular reactions involving the preparation of the reactants in selected energy states, the rate of dissociation of the activated molecule, and the partitioning of the excess energy among the final products, are fully discussed with the aid of 175 illustrations and over 1,000 references, most from the recent literature. Examples of both neutral and ionic reactions are presented. Many of the difficult topics are discussed at several levels of sophistication to allow access by novices as well as experts. Among the topics covered for the first time in monograph form is a discussion of highly excited vibrational/rotational states and intramolecular vibrational energy redistribution. Problems associated with the application of RRKM theory are discussed with the aid of experimental examples. Detailed comparisons are also made between different statistical models of unimolecular decomposition. Both quantum and classical models not based on statistical assumptions are described. Finally, a chapter devoted to the theory of product energy distribution includes the application of phase space theory to the dissociation of small and large clusters. The work will be welcomed as a valuable resource by practicing researchers and graduate students in physical chemistry, and those involved in the study of chemical reaction dynamics.
This book proposes a radical alternative to dominant views of the evolution of language, in particular the origins of syntax. The authors draw on evidence from areas such as primatology, anthropology, and linguistics to present a groundbreaking account of the notion that language emerged through visible bodily action. Written in a clear and accessible style, Gesture and the Nature of Language will be indispensable reading for all those interested in the origins of language.
The Hour of Our Nation's Agony offers a revealing look into the life of a Confederate soldier as he is transformed by the war. Through these literate, perceptive, and illuminating letters, readers can trace Lt. William Cowper Nelson's evolution from an idealistic young soldier to a battle-hardened veteran. Nelson joined the army at the age of nineteen, leaving behind a close-knit family in Holly Springs, Mississippi. He served for much of the war in the Third Corps of Robert E. Lee's Army of Northern Virginia. By the end of the conflict, Nelson had survived many major battles, including Fredericksburg, Chancellorsville, Gettysburg, and the Wilderness, as well as the long siege of Petersburg. In his correspondence, Nelson discusses in detail the soldier's life, religion in the ranks, his love for and heartbreak at being separated from his family, and Southern identity. Readers will find his reflections on slavery, religion, and the Confederacy particularly revealing. Seeing and participating in the slaughter of other human beings overpowered Nelson's romantic idealism. He had long imagined war as a noble struggle of valor, selflessness, and glory. But the sight of wounded men with "blood streaming from their wounds," dying slow, lonely deaths showed Nelson the true nature of war. Nelson's letters reveal the conflicting emotions that haunted many soldiers. Despite his bitter hatred of the "ruthless invaders of our beloved South," the sight of wounded Union prisoners moved him to compassion. Nelson's ability to write about irreconcilable moments when he felt both kindness and cruelty toward the enemy with introspection, candor, and sensitivity makes The Hour of Our Nation's Agony more than just a collection of missives. Jennifer Ford places Nelson squarely in the middle of the historiographic debate over the degree of disillusionment felt by Civil War soldiers, arguing that Nelson-like many soldiers-was a complex individual who does not fit neatly into one interpretation. Jennifer W. Ford is head of special collections and associate professor at the J. D. Williams Library at the University of Mississippi, where the where the collection containing Lt. Nelson's letters and other family documents is held.
This is a completely revised edition of a comprehensive and popular introduction to the fast moving area of Forensic Genetics. The text begins with key concepts needed to fully appreciate the subject and moves on to examine the latest developments in the field. Now illustrated in full colour throughout, this accessible textbook includes numerous references to relevant casework. With information on the full process of DNA evidence from collection at the scene of a crime to presentation in a legal context this book provides a complete overview of the field. Key Features: Greater in-depth coverage of kinship problems now covered in two separate chapters: one dealing with relationships between living individuals and the other covering identification of human remains. New chapter on non-human forensic genetics, including identification of bacteria and viruses, animals and plants. Self assessment questions to aid student understanding throughout the text. Now with full colour illustrations throughout New companion website Accessible introduction to forensic genetics, from the collection of evidence to the presentation of evidence in a legal context. Included in the Forensic Science Society 'Essentials in Forensic Science' book series. This edition is to be included in the Forensic Science Society 'Essentials of Forensic Science' book series aimed at advanced level undergraduates and new practitioners to the field.
With the publication of this book, newcomers to the field of steel rolling have a complete introductionto the cold rolling process, including the history of cold rolling, the equipment currentlyin use, the behavior of the rolling lubricant, the thermal and metallurgical aspects of the subject,mathematical models relating to rolling force and power requirements, strip shape, and thefurth er processing of cold-rolled steel. The first book in print to examine in detail the three componentsof the cold-rolling process- the mill, the work-piece, and the rolling lubricant-this bookcan be used as a training manual and as a source for reference and research. The manuscript version of this book has already been in use as a textbookin courses on cold rolling and rolling lubrication and is now published for thebenefit of all in-training personnel-both operating and supervisory-in theprimary metals industry and for undergraduate and graduate students inmetalworking. The interrelationships of the three components, described in terms ofmathematical models, are of considerable value to engineers associated withprimary metals and metal research, to mill builders, and to electrical equipmentsuppliers. For plant metallurgists, the book relates product quality to operating conditions;for the steel user and purchaser, it affords insight into the variousprocesses associated with the manufacture of steel sheet and strip.
A revisionist account of the liberation of Europe in World War II from the perspectives of Europeans offers insight into the more complicated aspects of the occupation, the cultural differences between Europeans and Americans, and their perspectives on the moral implications of military action. 75,000 first printing.
Reprint of the original. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
The fields of organizational climate and organizational culture have co-existed for several decades with very little integration between the two. In Organizational Climate and Culture: An Introduction to Theory, Research, and Practice, Mark G. Ehrhart, Benjamin Schneider, and William H. Macey break down the barriers between these fields to encourage a broader understanding of how an organization’s environment affects its functioning and performance. Building on in-depth reviews of the development of both the organizational climate and organizational culture literatures, the authors identify the key issues that researchers in each field could learn from the other and provide recommendations for the integration of the two. They also identify how practitioners can utilize the key concepts in the two literatures when conducting organizational cultural inquiries and leading change efforts. The end product is an in-depth discussion of organizational climate and culture unlike anything that has come before that provides unique insights for a broad audience of academics, practitioners, and students.
Multidisciplinary in scope and fully up to date with the latest advances in medical oncology and more, Bland and Copeland's The Breast, 6th Edition, covers every clinically relevant aspect of the field: cancer, congenital abnormalities, hormones, reconstruction, anatomy and physiology, benign breast disease, and more. In a practical, easy-to-use format ideal for today’s busy practitioners, this truly comprehensive resource is ideal for surgical oncologists, breast surgeons, general surgeons, medical oncologists, and others who need to stay informed of the latest innovations in this complex and fast-moving area. Offers the most comprehensive, up-to-date information on the diagnosis and management of, and rehabilitation following, treatment for benign and malignant diseases of the breast. Updates include an extensively updated oncoplastic section and extended medical and radiation oncology sections. Delivers step-by-step clinical guidance highlighted by hundreds of superb illustrations that depict relevant anatomy and pathology, as well as medical and surgical procedures. Reflects the collaborative nature of diagnosis and treatment among radiologists, pathologists, breast and plastic surgeons, radiation and medical oncologists, geneticists and other health care professionals who contribute to the management of patients with breast disease. Includes access to procedural videos that provide expert visual guidance on how to execute key steps and techniques.
This impressively comprehensive volume is a long-awaited and worthy successor to the now outdated 1978 classic, Evolution of African Mammals. A must-have reference work for everyone interested in mammalian evolution." David Pilbeam, Harvard University and the Peabody Museum of Archaeology and Ethnology --
Intro -- Contents -- Preface, by Michael M. Crow -- Acknowledgments -- Introduction: Solving for X with U -- 1 American Research Universities at a Fork in the Road -- 2 The Gold Standard in American Higher Education -- 3 The Varieties of Academic Tradition -- 4 Discovery, Creativity, and Innovation -- 5 Designing Knowledge Enterprises -- 6 A Pragmatic Approach to Innovation and Sustainability -- 7 Designing a New American University at the Frontier -- Conclusion: Toward More New American Universities -- Bibliography -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- R -- S -- T -- U -- W -- Z.
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