The interaction of neurotransmitters, neuromodulators and neuroactive drugs with receptors localized at the cell surface initiates a chain of molecular events leading to integrated neuronal responses to the triggering stimuli. Major advancements in the characterization and isolation of recep tor molecules have answered many quest ions regarding the nature of the ele ments that determine the specificity in these interactions. At the same time, recent studies have provided evidence that delicate regulation by intracellular enzymatic systems determines the efficiency of the stimulus response coupling process, mediates the interaction between receptors, operates in feedback control mechanisms and transduces signals from the receptors to various effector sites in a highly coordinated fashion. These studies are at the focus of the present volume, which is an outcome of a symposium held at the University of Vermont College of Medicine on March 21-23, 1986, in conjunction with the seventeenth annual meeting of the Amer ican Society for Neurochemistry. The symposium has demonstrated clearly that the concerted efforts of investigators in neurophysiology, biochemis try, pharmacology, cell-biology, molecular genetics, neurology, and psy chiatry are required to achieve better understanding of the processes under lying neuronal responsiveness. This volume includes contributions provided by prominent investigators in all these research areas. We hope that the readers will find here a useful source of information and ideas for stimu lating further studies which may serve to narrow the gap between basic neuroscience research and its clinical implications.
Three noted chiropractic educators from contending camps achieve surprising concord on many issues. This book is an omen of chiropractic's maturation and forthcoming integration with the larger health care community.
Multi-denominational congregations offer rich soil for new interpretations of what it means to be a church. These parishes have chosen to covenant together for worship, service, ministry, mission, and nurturing of faith across two or more denominational traditions. Daring to Share tells their stories, investigates their practices, and proposes a fresh vision of church for the twenty-first century. This book equips ordained and lay leaders for the formation and flourishing of such ministries. It describes five models of partnership, analyzes the parish life cycle, interprets how worship works, addresses constitutional and governance issues, and reflects theologically on the intersection of diversity and unity. What can we learn from these congregations? Studying their particular witness, struggles, and promise for the future fills a gap in both congregational studies and contemporary ecclesiology. Multi-denominational parishes are more than a convenient way to revitalize congregational ministry. They present new opportunities and approaches for sharing the gospel. Ecumenical convergence meets demographic realities to suggest a mission strategy that will transform local practice and, perhaps, the church itself. By daring to share, these churches challenge a fractured world.
Venture through the pages of How Consumers Pick a Hotel to learn the steps of selecting a target and using consumer behavior applications to segment the market to reach your target. Much as a consumer goes through the process of selecting a satisfying hotel, you can choose to use the information provided to make your hospitality career relaxing and satisfying. When you finish this fantastic reading journey, you’ll be prepared to offer services that meet the public’s demands, and you’ll possess the prerequisite knowledge and skills for developing your own strategic approach to a target market. As the many methods of segmentation are discussed in detail, you will also learn effective strategies for communicating with multiple segments. Ideal as a supplementary text for marketing and hospitality marketing courses, How Consumers Pick a Hotel provides a concise overview of consumer behavior and intertwines marketing theory with sound ways in which to implement the theory. This will both orient you and give you a solid base for understanding the principles in question. You will quickly grasp the various methods of segmentation, and the book’s “real-life” segmentation schemes will teach you how to apply them in day-to-day business. As the many methods of segmentation are discussed in detail, you will learn effective strategies for communicating with multiple segments. In the end, you will have acquired the prerequisite knowledge and skills for developing your own strategic approach to a target market. How Consumers Pick a Hotel is suitable both as a reference guide for practicing marketing managers and hospitality professionals who specialize in marketing and as a companion text for graduates and undergraduates who need to know the ABCs of target marketing. You’ll turn to it again and again for guidance and practical, easy suggestions!
This exhaustive reference includes new chapters and pedagogical features, as well as—for the first time—content on managing fragility factures. To facilitate fast, easy absorption of the material, this edition has been streamlined and now includes more tables, charts, and treatment algorithms than ever before. Experts in their field share their experiences and offer insights and guidance on the latest technical developments for common orthopaedic procedures, including their preferred treatment options.
How institutions shape the American presidency This incisive undergraduate textbook emphasizes the institutional sources of presidential power and executive governance, enabling students to think more clearly and systematically about the American presidency at a time when media coverage of the White House is awash in anecdotes and personalities. William Howell offers unparalleled perspective on the world’s most powerful office, from its original design in the Constitution to its historical growth over time; its elections and transitions to governance; its interactions with Congress, the courts, and the federal bureaucracy; and its persistent efforts to shape public policy. Comprehensive in scope and rooted in the latest scholarship, The American Presidency is the perfect guide for studying the presidency at a time of acute partisan polarization and popular anxiety about the health and well-being of the republic. Focuses on the institutional structures that presidents must navigate, the incentives and opportunities that drive them, and the constraints they routinely confront Shows how legislators, judges, bureaucrats, the media, and the broader public shape the contours and limits of presidential power Encourages students to view the institutional presidency as not just an object of study but a way of thinking about executive politics Highlights the lasting effects of important historical moments on the institutional presidency Enables students to grapple with enduring themes of power, rules, norms, and organization that undergird democracy
Psychology is of interest to academics from many fields, as well as to the thousands of academic and clinical psychologists and general public who can't help but be interested in learning more about why humans think and behave as they do. This award-winning twelve-volume reference covers every aspect of the ever-fascinating discipline of psychology and represents the most current knowledge in the field. This ten-year revision now covers discoveries based in neuroscience, clinical psychology's new interest in evidence-based practice and mindfulness, and new findings in social, developmental, and forensic psychology.
Cottrell's Neuroanesthesia 5th Edition, edited by James E. Cottrell, MD, FRCA and William L. Young, MD, delivers the complete and authoritative guidance you need to ensure optimal perioperative safety for neurosurgical patients. Integrating current scientific principles with the newest clinical applications, it not only explains what to do under any set of circumstances but also why to do it and how to avoid complications. Comprehensive updates reflect all of the latest developments in neurosurgical anesthesia, and contributions from many new experts provide fresh insights into overcoming tough clinical challenges. New co-editor William L. Young, MD joins James E. Cottrell, MD, FRCA at the book's editorial helm, providing additional, complementary expertise and further enhancing the book's authority. New chapters keep you current on interventional neuroradiology, anesthetic management of patients with arteriovenous malformations and aneurysms, awake craniotomy, epilepsy, minimally invasive and robotic surgery, and pregnancy and neurologic disease. Comprehensive updates reflect all of the latest developments in neurosurgical anesthesia, and contributions from many new experts provide fresh insights into overcoming tough clinical challenges. Comprehensive and broad coverage of all important aspects of neuroanesthesia, including special patient populations, enables you to find reliable answers to any clinical question. Chapters written by neurointensivists, neurosurgeons, and radiologists provide well-rounded perspectives on each topic. A consistent, logical organization to every chapter makes answers easy to find quickly. Clear conceptual illustrations make complex concepts easier to understand at a glance.
This book is an evidence-based review of the practical challenges of dealing with patients receiving dialysis. The first section covers technical and procedural considerations such as choosing the hemodialysis membrane and choosing the best dialysis option. The second section covers clinical considerations such as infection and the treatment of specific renal disease complications. The book includes numerous illustrations and tables and drug charts for dialysis patients. This edition's current outcomes chapter has been expanded to include patient depression and improving quality of care. New chapters cover dialysis in the ICU, valvular heart disease, and pre-emptive renal transplantation.
Montana: A History of Two Centuries first appeared in 1976 and immediately became the standard work in its field. In this thoroughgoing revision, William L. Lang has joined Michael P. Malone and Richard B. Roeder in carrying forward the narrative to the 1990s. Fully twenty percent of the text is new or revised, incorporating the results of new research and new interpretations dealing with pre-history, Native American studies, ethnic history, women's studies, oral history, and recent political history. In addition, the bibliography has been updated and greatly expanded, new maps have been drawn, and new photographs have been selected.
Interweaves the conditions of Canadian prisoners of war during the two world and the Korean wars, with the efforts of Canadian governmental and non-governmental organizations to assist them with relief supplies or to secure their release. Also shows how the dedication and concerns of the Canadians helped shape international laws and organizations relating to prisoners of war. Includes many old photographs. Annotation copyright by Book News, Inc., Portland, OR
The 112th New York Infantry Regiment served 1,017 days during the Civil War, from 1862 to 1865. They campaigned in four states, fought in 16 battles and lost 324 men, including two regimental commanders. This unit history is based on the personal papers of Chaplain William Lyman Hyde, including his war diary, journals, reports and letters to his wife. A prolific writer, Hyde's remarkable story of service to God and country is told in his own words, providing vivid depictions of camp life, combat and its aftermath and the daily trials faced by the "Chautauqua Regiment.
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