This second edition is extensively revised throughout with expanded discussion of modeling fundamentals and coverage of advances in model calibration and uncertainty analysis that are revolutionizing the science of groundwater modeling. The text is intended for undergraduate and graduate level courses in applied groundwater modeling and as a comprehensive reference for environmental consultants and scientists/engineers in industry and governmental agencies. - Explains how to formulate a conceptual model of a groundwater system and translate it into a numerical model - Demonstrates how modeling concepts, including boundary conditions, are implemented in two groundwater flow codes-- MODFLOW (for finite differences) and FEFLOW (for finite elements) - Discusses particle tracking methods and codes for flowpath analysis and advective transport of contaminants - Summarizes parameter estimation and uncertainty analysis approaches using the code PEST to illustrate how concepts are implemented - Discusses modeling ethics and preparation of the modeling report - Includes Boxes that amplify and supplement topics covered in the text - Each chapter presents lists of common modeling errors and problem sets that illustrate concepts
A thriving fur trade post between 1830 and 1860, Fort Clark, in what is today western North Dakota, also served as a way station for artists, scientists, missionaries, soldiers, and other western chroniclers traveling along the Upper Missouri River. The written and visual legacies of these visitors—among them the German prince-explorer Maximilian of Wied, Swiss artist Karl Bodmer, and American painter-author George Catlin—have long been the primary sources of information on the cultures of the Mandan and Hidatsa Indians, the peoples who met the first fur traders in the area. This book, by a team of anthropologists, is the first thorough account of the fur trade at Fort Clark to integrate new archaeological evidence with the historical record. The Mandans built a village in about 1822 near the site of what would become Fort Clark; after the 1837 smallpox epidemic that decimated them, the village was occupied by Arikaras until they abandoned it in 1862. Because it has never been plowed, the site of Fort Clark and the adjacent Mandan/Arikara village are rich in archaeological information. The authors describe the environmental and cultural setting of the fort (named after William Clark of the Lewis and Clark expedition), including the social profile of the fur traders who lived there. They also chronicle the histories of the Mandans and the Arikaras before and during the occupation of the post and the village. The authors conclude by assessing the results—published here for the first time—of the archaeological program that investigated the fort and adjacent Indian villages at Fort Clark State Historic Site. By vividly depicting the conflict and cooperation in and around the fort, this book reveals the various cultures’ interdependence.
Written by the world’s foremost leaders in the field of nosocomial infections, Bennett & Brachman’s Hospital Infections, 7th Edition, is a must-have text for preventing Hospital-Acquired Infections (HAIs) in all inpatient and outpatient healthcare settings. This comprehensive volume provides up-to-date, authoritative coverage on all aspects of this vital topic, with editor Dr. William R. Jarvis leading a team of notable contributors from the U.S. Centers for Disease Control and Prevention, as well as additional authors who provide an international perspective on HAIs. The newly revised and expanded seventh edition continues to be an invaluable resource for anyone working in infection prevention and control, quality assurance or risk management in healthcare settings.
The third edition of this monograph continues to have the goal of providing an overview of current thought about the spinal cord mechanisms that are responsible for sensory processing. We hope that the book is of value to both basic and clinical neuroscientists. Several changes have been made in the presentation, as well as additions because of the research advances that have been made during the past decade. Chapters 3 and 4 in the previous edition have been subdivided, and now the morphology of primary afferent neu rons of the dorsal root ganglia is described in Chapter 3 and the chemical neuroanatomy of these neurons in Chapter 4. The description of the dorsal horn in the previous Chapter 4 is now included in Chapter 5, and the chemical neuroanatomy of the dorsal horn in Chapter 6. Furthermore, discussions of the descending control systems have now been consolidated at the end of Chapter 12. The authors would like to express their appreciation for the help provided by several individuals. R.E.C. wishes to acknowledge the many things he learned about primary afferent neurons from conversations with Dr S. N. Lawson. He also thanks Lyn Shilling for her assistance with the typing. WDW thanks Dr Nada Lawand for her critical reading of parts of the manuscript, Rosaline Leigh for help with the manuscript, and Griselda Gonzales for preparing the illustrations.
In the mid-twentieth century, Plainsboro was a quiet farm village with more cows than people. Today, it is a community of more than twenty thousand residents, beautiful homes, and thriving businesses. With nearly two hundred vintage photographs, Plainsboro takes the reader back to a simpler time and provides an opportunity to see life as it once was in this quaint agricultural town. With this volume, spanning a period from the late 1800s to the early 1970s, readers will meet the town's founding fathers, explore old dirt pathways that are today's tree-lined streets, and view the original structures of the village. Included are exciting and unexpected photographs of local research and experiments, such as hovercraft, a fusion plant, and a nuclear reactor; the famous Walker-Gordon Dairy; and the Rotolactor, a giant merry-go-round that could milk fifty cows at a time. Also featured is Plainsboro's most famous citizen, the very first Elsie the Cow, who lived at the Walker-Gordon farm. Plainsboro captures the town's history from its early, unassuming potato farms to the astounding government research conducted here just decades ago.
Since publication of the First Edition in 1982, Hemostasis and Thrombosis has established itself as the pre-eminent book in the field of coagulation disorders. No other book is as inclusive in scope, with coverage of the field from the standpoint of both basic scientists and clinicians. This comprehensive resource details the essentials of bleeding and thrombotic disorders and the management of patients with these and related problems, and delivers the most up-to-date information on normal biochemistry and function of platelets or endothelial cells, as well as in-depth discussions of the pharmacology of anticoagulant, fibrinolytic, and hemostatic drugs. NEW to the Sixth Edition... • A new team of editors, each a leader in his field, assures you of fresh, authoritative perspectives. • Full color throughout • A companion website that offers full text online and an image bank. • A new introductory section of chapters on basic sciences as related to the field • Entirely new section on Hemostatic and Thrombotic Disorders Associated with Systemic Conditions includes material on pediatric patients, women's health issues, cancer, sickle cell disease, and other groups. • Overview chapters preceding each section address broad topics of general importance. This is the tablet version which does not include access to the supplemental content mentioned in the text.
The purpose of this book is to present an overview of advances in both retinal and retinoic acid synthetic chemistry and biology. Chapters are written by research workers who are active in these fields. Emphasis is placed on structure-activity relationships. It includes topics of cell differentiation, maintenance of cell morphology, and vision. This reference contains a special section on assays which were developed to measure retinoid activity. This book is ideal for those interested in the fields of photobiology, organic chemistry, biological chemistry, and nutrition.
This book is a companion to “Natural Gas Hydrate in Oceanic and Permafrost Environments” (Max, 2000, 2003), which is the first book on gas hydrate in this series. Although other gases can naturally form clathrate hydrates (referred to after as ‘hydrate’), we are concerned here only with hydrocarbon gases that form hydrates. The most important of these natural gases is methane. Whereas the first book is a general introduction to the subject of natural gas hydrate, this book focuses on the geology and geochemical controls of gas hydrate development and on gas extraction from naturally occurring hydrocarbon hydrates. This is the first broad treatment of gas hydrate as a natural resource within an economic geological framework. This book is written mainly to stand alone for brevity and to minimize duplication. Information in Max (2000; 2003) should also be consulted for completeness. Hydrate is a type of clathrate (Sloan, 1998) that is formed from a cage structure of water molecules in which gas molecules occupying void sites within the cages stabilize the structure through van der Waals or hydrogen bonding.
Pancreatitis is an inflammation of the pancreas. The pancreas secretes digestive enzymes into the small intestine through a tube called the pancreatic duct. These enzymes help digest fats, proteins, and carbohydrates in food. The pancreas also releases the hormones insulin and glucagon into the bloodstream. These hormones help the body use the glucose it takes from food for energy. Normally, digestive enzymes do not become active until they reach the small intestine, where they begin digesting food. But if these enzymes become active inside the pancreas, they start 'digesting' the pancreas itself. Acute pancreatitis occurs suddenly and lasts for a short period of time and usually resolves. Chronic pancreatitis does not resolve itself and results in a slow destruction of the pancreas. In severe cases, bleeding, tissue damage, and infection may occur. Pseudocysts, accumulations of fluid and tissue debris, may also develop. And enzymes and toxins may enter the bloodstream, injuring the heart, lungs, and kidneys, or other organs. This new book presents the latest research from around the world in this field.
In the tradition of Schwarz and King, this work brings together internationally renowned contributors from the front lines of pulmonary medicine and research in one timely and authoritative compendium. It takes a new and comprehensive look at a large medical problem - chronic obstructive lung diseases are a problem of global importance and the incidence of COPD is increasing in many countries and COPD is an important cause of morbidity and mortality. The focus is on the pathobiology of COPD and emphysema, on the exacerbation of COPD and on treatment options.
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