This book is aimed at informing organic chemists and natural products chemists on the use of NMR for structure elucidation to enable them to ensure they yield the most reliable possible data in the minimum possible time. It covers the latest pulse sequences, acquisition and processing methods, practical areas not covered in most texts e.g. detailed consideration of the relative advantages and disadvantages of different pulse sequences, choosing acquisition and processing parameters to get the best possible data in the least possible time, pitfalls to avoid and how to minimize the risks of getting wrong structures. Useful in industrial, pharma or research environments, this reference book is for anyone involved with organic chemistry research and, in particular, natural products research requiring advice for getting the best results from the NMR facilities.
I began this effort to tell the story of our ministry in order that our grandchildren might know something of our lives before they came along. All of them arrived on the scene after my retirement from the Air Force Chaplaincy. Most of them remember us only later after we had retired from serving Methodist churches and were living at Canyon Lake, Texas. Because of distances most of them have heard only bits and pieces of our (Pat and myself) ministry challenges throughout the world. This is an effort to share with them the exciting and sometimes difficult experiences of those earlier years.
Spanning forty years, this book recreates the spirit of a golden age of exploration and travel when adventure-seeking men and women made grand tours into an unknown wilderness and alpinists, scientists, photographers, and tourists discovered for the first time the secrets of a great and varied land. In the mighty Selkirk Mountains of Canada lies Rogers Pass which was the scene of three major events in the history of North America: in 1884, it presented an enormous obstacle to the Canadian Pacific Railway in its drive to connect the new nation coast-to-coast; it became the site of the first modern, European-style resort hotel in the mountains; and it was the first locality to attract the attention of serious mountaineers from around the world. Putnam blends these three events and weaves them into an accurate early history of the region. He shares with us the heroic, often tragic, tale of the Canadian Pacific Railway. He takes us into the magnificent surroundings of the Great Glacier and we see the modest Glacier House develop through the years into a world- famous luxury hotel. And as the Rogers Pass Glacier area becomes the focal point in the fledgling sport of alpinism in North America, we join the earliest expeditions undertaken in the Selkirk Range. The focus of the book, however, is on the people whose paths cross at Glacier House -- and the author lets them tell their own stories. The personalities of the railroad executives and the hotel staff emerge from correspondence and reports. As a basis of much of the book, Putnam has included many firsthand accounts from the Glacier House register. Known as "The Scrapbook," it contains the handwritten accounts of virtually every notable climber and mountain explorer of the early era. Magnificent historical photographs, many of them never before published, exquisitely illustrate the book. The forty-year saga is vividly retold through these rare photographs of the scenes those early adventurers witnessed when they first visited the Great Glacier and its house.
Few events in Civil War history have generated such deliberate mythmaking as the retreat that ended at Appomattox. William Marvel offers the first history of the Appomattox campaign written primarily from contemporary source material, with a skeptical eye toward memoirs published well after the events they purport to describe. Marvel shows that during the final week of the war in Virginia, Lee's troops were more numerous yet far less faithful to their cause than has been suggested. He also proves accounts of the congenial intermingling of the armies at Appomattox to be shamelessly overblown and the renowned exchange of salutes to be apocryphal.
At the heart of Houston stands the Texas Medical Center. This dense complex of educational, clinical, and hospital facilities offers state-of-the-art patient care, basic science, and applied research in more than fifty medicine-related institutions. Three medical schools, four schools of nursing, and schools of dentistry, public health, and pharmacology occupy the thousand-acre campus. But none of this would exist if not for the generosity and vision of Monroe Dunaway Anderson, who, in 1936, established the foundation that bears his name. The M. D. Anderson Foundation ultimately became the driving force behind creating and shaping this leading-edge medical complex into what it is today. Enduring Legacy: The M. D. Anderson Foundation and the Texas Medical Center provides a unique perspective on the indispensable role the foundation played in the creation of the Texas Medical Center. It also offers a case study of how public and private institutions worked together to create this veritable city of health that has since become the largest medical complex in human history. Historian William Henry Kellar caps off a decade of research on institutions and characters associated with the Texas Medical Center. He draws on oral histories, extensive archival work, and a growing secondary literature to provide an absorbing account of this leading institution of modern medicine and the philanthropy that made it possible.
Keep abreast of the latest advances in this complex field with the 5th Edition of Clinical Immunology: Principles and Practice. This substantially revised edition by Drs. Robert R. Rich, Thomas A. Fleisher, William T. Shearer, Harry W. Schroeder, Jr., Anthony J. Frew, and Cornelia M. Weyand, offers authoritative guidance from some of the most respected global leaders in immunology, helping you navigate today’s latest knowledge and evidence-based practices that result in improved patient care. This trusted resource features sweeping content updates, rewritten chapters, a highly clinical perspective, and an easy-to-use organization designed to enhance your diagnosis and management skills in daily practice. User-friendly format features color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles. Includes new chapters on the Microbiota in Immunity and Inflammation, Immune Responses to Fungi, and Genetics and Genomics of Immune Response. Features extensive revisions to many chapters, including the Major Histocompatibility Complex, Multiple Sclerosis, Diabetes and Related Autoimmune Diseases, Biologic Modifiers of Inflammation and Tumor Immunotherapy. Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics. Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more. Summarizes promising research and development anticipated over the next 5-10 years with "On the Horizon" boxes and discussion of translational research. Includes new multiple choice questions in every chapter online, ideal for allergists and rheumatologists seeking certification or recertification in these subspecialties. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
In this book, William Caferro asks if the Renaissance was really a period of progress, reason, the emergence of the individual, and the beginning of modernity. An influential investigation into the nature of the European Renaissance Summarizes scholarly debates about the nature of the Renaissance Engages with specific controversies concerning gender identity, economics, the emergence of the modern state, and reason and faith Takes a balanced approach to the many different problems and perspectives that characterize Renaissance studies
Use the latest research to bring differentiated instruction to today′s inclusive classrooms! With flipped classrooms, response to intervention, and technology discussed as differentiated instructional tools, this book has it all! Teachers need 21st century resources that help them provide high-quality, differentiated instruction for all students. In this new edition of his best-selling resource, William Bender draws on the latest brain research, technology, and educational initiatives to bring a new focus to differentiating instruction in the context of the Common Core State Standards. By weaving together differentiated instruction, Response to Intervention, and educational technology, educators can increase achievement among students with learning disabilities and also foster the development of 21st-century skills. This updated guide offers Specific strategies for differentiating instruction within an RTI framework and in the context of the Common Core State Standards Strategies for using technology to instruct and assess students with learning disabilities Teaching tips and concrete examples of brain-friendly instruction Guidance on a range of supportive instructional techniques Additional strategies based on the latest research in metacognition Up-to-date techniques such as using Khan Academy, flipped classes, and wikis to enhance learning in general and special education settings This new edition of Differentiating Instruction for Students With Learning Disabilities offers the tools and strategies educators need to maximize achievement for all students. "The ideas in this book are wonderful! They are new, innovative, current, interesting, and very practical. I could easily implement some of these ideas in my classroom tomorrow!" —Rachel Aherns, Teacher Westridge Elementary School, West Des Moines, IA "Between these pages you will find ample strategies of how to effectively and efficiently individualize instruction for a classroom of diverse learners, without having to spend countless hours before and after a lesson preparing and assessing." —Jessica Purcell, Teacher Morehead City Middle School, Morehead City, NC
Woody Allen has accomplished that which no American filmmaker in the modern era has or perhaps ever will: directing to date 49 films (47 full-length theatrical releases, 1 short film in an anthology, and 1 television film), writing 42 of those films (and co-writing the remaining 7) and acting in 29 of them. Collectively, these films have earned Allen 4 Oscars (1 for Best Director; 3 for Best Screenplay), as well as another 6 Academy Award nominations for Best Director, 13 for Best Screenplay and 1 for Best Actor. Actors, members of his film staff, and his producers have received 7 Oscars and another 20 nominations. All told, his films have garnered 132 awards and another 209 nominations from American and international bodies. Historical Dictionary of Woody Allen contains a chronology, an introduction, a filmography, an appendix, and an extensive bibliography. The dictionary section has over 600 cross-referenced entries on the actors, actresses, cinematographers, editors, designers, and producers he’s worked with as well as his films and awards. This book is an excellent resource for students, researchers, and anyone wanting to know more about Woody Allen.
Make the painless transition from low tech to tech friendly! Are you struggling to embrace technology that advances at lightning speed? Or are you just plain perplexed? With new developments announced almost on a daily basis, many teachers don′t know where to start. If you′re one of those teachers making the transition to tech—willingly or not—Cool Tech Tools for Lower Tech Teachers is the resource for you. In understandable language, it describes how exactly you can use tools like webquests, wikis, social networking apps, and podcasts to enhance your lessons and keep kids engaged. William Bender and Laura Waller put technology within your reach by: Framing each tool in the context of what you need to know Defining the tool in easy-to-understand language; there′s no tech-speak Guiding you through implementation step by step Providing sample lesson plans to get you started Explaining how some tools can also be used for professional development With Cool Tech Tools for Lower Tech Teachers, Bender and Waller prove that technology can be painless and productive. What′s more, you′ll even come to love it! "This book provides a wealth of ideas for teachers who would like to use technology but do not know where to begin. Each chapter provides a lens into specific categories of use and associated websites." —Bena Kallick, Educational Consultant "This book is an excellent resource for both new and experienced educators looking to make the most of Web 2.0 resources for teaching and learning. It can be used individually, but I think it would be most beneficial (and fun!) to use in small groups of educators as they support and surprise one another with their explorations and discoveries." —Chris Toy, Educational Consultant, Learning Capacity Unlimited Graduate School Instructor, University of Southern Maine
Clinical hypertension is one of the most serious long-term problems associated with heart disease. This companion to Braunwald's Heart Disease focuses in depth on this key area of cardiovascular medicine. Complete with practical clinical tools for management, it helps you manage the chronic problems of your hypertensive patients. It covers everything from epidemiology and pathophysiology through diagnosis, risk stratification, treatment, outcome studies, concomitant diseases, special populations and special situations, and future treatments. Addresses management of all special populations with chronic hypertensive disease. Includes Clinical Pearls for reducing complications of hypertension. Discusses hypertension and concomitant disease. Provides information on the practical management of hypertension and its role in complex diseases Emphasizes prevention of hypertensive diseases. Covers behavior management as an integral part of treatment plan for hypertensives and pre-hypertensives. Assesses drugs and other forms of treatment. Presents current clinical guidelines for the U.S., Canada, and Europe. Encourages aggressive patient management to ensure minimal risk of further cardiovascular problems.
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