When William Bradford Huie, a reporter for H. L. Mencken's American Mercury, joined the U.S. Navy in 1943, he received a commission as a public relations officer in the little-known Civil Engineer's Corps Construction Battalions--the Seabees. With the publication of Can Do! the following year, Americans soon came to appreciate the significance of the corps' work and the danger of their wartime activities. As readable and entertaining today as it was some fifty years ago, this account tells the story of the Seabees who landed with the Marines at Guadalcanal and Wake Island, Sicily and Salerno. Experienced civilian engineers, carpenters, steam-shovel operators, plumbers, truck drivers, surveyors, and the like, they landed with the first waves of American assault troops, bringing heavy equipment ashore to build roads, bridges, and airfields and repair whatever they could. Often working under enemy fire, they incurred many casualties and won the deep respect of everyone who came into contact with them. Huie's book is filled with spirited accounts of the Seabees'achievements in the Aleutians, the South Sea islands, Europe, and Africa. A passionate and convincing advocate, Huie wrote the book not only to call attention to their accomplishments but to serve as an inspiration to others, and he often has the Seabees tell their stories in their own words. Appendixes offer valuable details, including lists of casualties, award recipients, and Seabees' poems. An introduction by Donald R. Noble is included in this new paperback edition.
This book presents both the fundamentals concepts and latest achievements of a field that is growing in importance since it represents a possible solution for global energy problems. It focuses on an atomic-level understanding of heterogeneous catalysis involved in important energy conversion processes. It presents a concise picture for the entire area of heterogeneous catalysis with vision at the atomic- and nano- scales, from synthesis, ex-situ and in-situ characterization, catalytic activity and selectivity, to mechanistic understanding based on experimental exploration and theoretical simulation. The book: Addresses heterogeneous catalysis, one of the crucial technologies employed within the chemical and energy industries Presents the recent advances in the synthesis and characterization of nanocatalysts as well as a mechanistic understanding of catalysis at atomic level for important processes of energy conversion Provides a foundation for the potential design of revolutionarily new technical catalysts and thus the further development of efficient technologies for the global energy economy Includes both theoretical studies and experimental exploration Is useful as both a textbook for graduate and undergraduate students and a reference book for scientists and engineers in chemistry, materials science, and chemical engineering
Diverse alterations of glycosylation occur in diseases such as cancer, metastasis, leukemia, inflammatory and other diseases. The glycosylation abnormalities found in disease are the result of complex rearrangements of the oligosaccharide assembly by glycosyltransferases. This volume reviews several mechanisms that may underly the extremely complex alterations in disease. Disease specific glycosylation may contribute to the disease process by altering cellular functions, or may be exploited therapeutically. Specific therapy may be aimed at correcting glycosylation abnormalities based on knowledge of the mechanisms leading to the disease phenotype and the three-dimensional interactions between carbohydrates and carbohydrate-binding molecules.
As a result of the industrial revolution, man's technological achievements have been truly great, increasing the quality of life to almost unimagined proportions; but all this progress has not been accomplished without equally un imagined health risks. Sufficiently diagnostic short-term assay procedures have been developed in recent years for us to determine that there are mutagenic agents among thou sands of chemicals to which the human population is exposed today. These chemicals were not significantly present prior to the indus trial revolution. As of today, there are no procedures available which have been adequately demonstrated to assess individual sus ceptibility to genotoxic exposures, and as a result we have had to rely on extrapolating toxicological data from animal model systems. The question is can we afford to allow such an increased environ mental selection pressure via mutagenic exposures to occur without expecting adverse long-term effects on our health. It is apparent from this line of reasoning that what is lacking and immediately needed are test procedures that can be applied to humans to assess genotoxic exposure as well as individual susceptibility to it. There have already been two conferences which have focused at tention on this research area. "Guidelines for studies of human populations exposed to mutagenic and reproductive hazards" (A. D. Bloom, ed., March of Dimes Birth Defects Foundation, White Plains, New York, 1981) and "Indicators of genotoxic exposure in humans" (Banbury Report 13, B. A. Bridges, B. E. Butterworth, and I. B.
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