This book contains the papers of the Fourth Seminar in American Philosophy that was held in Winterthur, Switzerland, September 3-7, 1973. The subject of the seminar was the Philosophy of William James, which can be described as pragmatism. James himself understood by it »a new name for old ways of thinking« and put life, practice and action in the centre of his thinking – not the thinking itself as he regarded it as a »new« achievement in the development of mankind.
Packed with practical, up-to-date guidance, Essentials of Physical Medicine and Rehabilitation, 4th Edition, by Walter R. Frontera, MD, PhD; Julie K. Silver, MD; and Thomas D. Rizzo, Jr., MD, helps you prevent, diagnose, and treat a wide range of musculoskeletal disorders, pain syndromes, and chronic disabling conditions in day-to-day patient care. This easy-to-use reference provides the information you need to improve patient function and performance by using both traditional and cutting-edge therapies, designing effective treatment plans, and working with interdisciplinary teams that meet your patients' current and changing needs. An easy-to-navigate format provides quick access to concise, well-illustrated coverage of every essential topic in the field. - Presents each topic in a consistent, quick-reference format that includes a description of the condition, discussion of symptoms, examination findings, functional limitations, and diagnostic testing. An extensive treatment section covers initial therapies, rehabilitation interventions, procedures, and surgery. - Contains new technology sections in every treatment area where recently developed technologies or devices have been added to the therapeutic and rehabilitation strategies, including robotic exoskeletons, wearable sensors, and more. - Provides extensive coverage of hot topics in regenerative medicine, such as stem cells and platelet rich plasma (PRP), as well as a new chapter on abdominal wall pain. - Delivers the knowledge and insights of several new, expert authors for innovative perspectives in challenging areas. - Offers a clinically-focused, affordable, and focused reference for busy clinicians, as well as residents in need of a more accessible and targeted resource. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Growth Regulation and Carcinogenesis discusses topics such as growth factors, including stimulators and inhibitors of proliferation; networks in proliferation regulation; differentiation-inducing factors; origins of neoplasia and their relationship to growth control; genetic alterations in cellular regulatory machinery; extrachromosomal phenomena; non-genotoxic carcinogens; immortalization and transformation of cells; and the role of cell production, cell function, and cell elimination in physiological growth control.
From the latest vaccination evidence, recommendations, and protocols . . . to new vaccine development and the use of vaccines in reducing disease, Plotkin's Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization. - Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines. - Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality. - Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. - Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
From the development of each vaccine to its use in reducing disease, Plotkin's Vaccines, 7th Edition, provides the expert information you need to provide optimal care to your patients. This award-winning text offers a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Includes complete information for each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, epidemiology, and public health and regulatory issues – plus complete information for each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Covers the new oral cholera and zoster vaccines, as well as newly licensed meningococcal group B vaccines and a newly licensed dengue vaccine. - Brings you up to date on successful human trials of Ebola vaccines, an enterovirus 71 vaccine licensed in China, and new recommendations and changes to polio vaccines. - Features a new chapter on maternal immunization. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
How to identify optimal phase II trial designs Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, A Practical Guide to Designing Phase II Trials in Oncology sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomization, and considering both academic and industry perspectives. A comprehensive and systematic library of available phase II trial designs is included, saving time otherwise spent considering multiple manuscripts, and real-life practical examples of using this approach to design phase II trials in cancer are given. A Practical Guide to Designing Phase II Trials in Oncology: Offers a structured and practical approach to phase II trial design Considers trial design from both an academic and industry perspective Includes a structured library of available phase II trial designs Is relevant to both clinical and statistical researchers at all levels Includes real life examples of applying this approach For those new to trial design, A Practical Guide to Designing Phase II Trials in Oncology will be a unique and practical learning tool, providing an introduction to the concepts behind informed decision making in phase II trials. For more experienced practitioners, the book will offer an overview of new, less familiar approaches to phase II trial design, providing alternative options to those which they may have previously used.
This book presents the most common skin diseases of children, which account for more than 90% of the presenting cases. In each chapter, the differential diagnostic possibilities are shown in a table where the most important distinguishing features are summarized. Treatment is presented in considerable detail, reflecting the current literature as well as the clinical experience in two large German pediatric dermatology clinics. The scientific names of all recommended medications are given so that the book can be used by readers around the globe, rather than just those with access to European medications. Tips are included for the treating physician on how to best tailor the various therapy regimens and anticipate the course of the disease. Recent advances in dermatologic therapy including tacrolimus, pimecrolimus, and imiquimod are included. The appendix contains detailed practical information on the choice of an appropriate vehicle, as well as on antibiotics, antihistamines, and topical corticosteroids.
Neil Whitehead offers a scholarly edition of Sir Walter Raleigh's account of his expedition to South America in search of an indegenous 'empire' in the highlands of Guiana.
AARP Digital Editions offer you practical tips, proven solutions, and expert guidance. In Clean, Green, and Lean, a renowned naturopathic doctor shows you how to get lean and be green while helping to save the planet. Now you can lose weight and be good to the environment, too—without starvation diets, calorie counting, complicated meal plans, or even having to exercise. Dr. Walter Crinnion, a naturopathic doctor and environmental medicine physician, shows you how to clean up your diet and clear out your body and home to eliminate unwanted pounds and toxins from your life. You'll be able to get rid of nagging health problems such as allergies and fatigue and enjoy greater energy and a greener planet. Clean, Green, and Lean: Shares an effective program to shed pounds and stay healthy by getting rid of toxins in your body and your life in just four weeks Combines losing weight with being good to the environment Can help reduce aches and pains, depression, and other health problems Is written by one of the country's foremost authorities on environmental medicine who has appeared on The View and other programs If you're serious about losing weight and safeguarding your health, follow the expert advice of Dr. Crinnion and start getting clean, green, and lean today.
Geosciences and in particular numerical weather prediction are demanding the highest levels of available computer power. The European Centre for Medium-Range Weather Forecasts, with its experience in using supercomputers in this field, organizes every other year a workshop bringing together manufacturers, computer scientists, researchers and operational users to share their experiences and to learn about the latest developments. This book provides an excellent overview of the latest achievements in and plans for the use of new parallel techniques in meteorology, climatology and oceanography. The proceedings have been selected for coverage in: . OCo Index to Scientific & Technical Proceedings (ISTP CDROM version / ISI Proceedings).
The updated 2nd edition of this accessible and in-depth resource firmly relates molecular and cellular biology to the study of human physiology and disease. Leading physiologists present you with practical, accurate coverage, continually emphasizing the clinical implications of the material. Each chapter explains the principles and organization of each body system, while more than 800 high-quality, full-color line drawings and prominently featured clinical examples clarify every concept. This exceptionally detailed and comprehensive guide to physiology is ideal for a rich, straightforward, state-of-the-art understanding of this essential subject. Provides clinical examples of disordered physiology in prominent boxes throughout the text for at-a-glance access to important content. Clarifies concepts with the use of 800 color drawings that feature balloon captions explaining key processes. Presents material in a consistent style to make the text readable and easy to understand. Offers a practical organization by body system for an intuitive and accessible approach to physiology. Features access to the complete contents of the book online, plus a full image collection, animations, 150 review questions, and supplemental web notes for more detailed information. Keeps you current with updated material, including a new chapter on Physiology of Aging and a new section on hemostasis. Offers the latest visual guidance with a revised and updated art program.
The First Textbook to Take an Integrative Approach to Neurological Diagnosis This introductory, full-color text teaches students and practitioners how to combine neurological history and physical examination so they can localize pathologies within the nervous system and determine appropriate treatment. It provides a wealth of illustrations that emphasize the functioning nervous system, in addition to an invaluable DVD for further exploration and access to a state-of-the-art website with additional materials that are updated periodically. Give Practitioners the Confidence to Differentiate, Diagnose, and Build Treatment Plans Provides a wealth of illustrations that emphasize the functioning nervous system Neuroanatomical drawings related to case studies Informative tables with relevant clinical data Radiographic images, EEGS, microscopic images, and other diagnostic tools Includes an invaluable DVD for further exploration User-friendly worksheets to provide a proven methodology for evaluation All color illustrations from the book Flash animations of various pathways, reflexes, and circuits Neuroimaging primer to boost understanding of CT and MRI sequences Supplementary e-cases and diagnostic images A wealth of references for self-guided study Offers access to a state-of-the-art website All of the features on the DVD Additional supplementary materials to be added periodically Demystifies Neurological Problem Solving Section I: Covers the Basics of Neurological Problem Solving Provides a full synopsis of the nervous system Explains key aspects of the neurological examination Delves into clinical problem solving Includes a Fail Safe Localization/Etiology Checklist Covers lesions caused by trauma, muscle diseases, genetic and degenerative diseases, vascular problems, drugs and toxins, infections, and autoimmune disorders Section II: Applies the Basics to Clinical Cases Presents full case examinations of a nine-member fictional family Demonstrates clinical data extraction, definition of main clinical points, relevant neuroanatomy, and the localization process Covers a wide range of disease processes, including spinal cord syndromes and traumas, vascular injury, and seizures Details autoimmune, neoplastic, degenerative, and genetic disorders Differentiates between various causes of seizures, stroke, and Parkinsonism Provides complete case summaries, treatment, management, and outcomes
With your heavy case load, you can't afford to waste time searching for answers. Cardiology, 3rd Edition, by Drs. Crawford, DiMarco, and Paulus, offers you just the practical, problem-based guidance you need to quickly overcome any clinical challenge. 8 color-coded sections cover the 8 major clinical syndromes of cardiovascular disease—each section a virtual "mini textbook" on its topic! 40 new chapters keep you up to date with the latest advances in the field, while more than 2,000 lavish, high-quality illustrations, color photographs, tables, and ECGs capture clinical manifestations as they present in practice. It’s current, actionable information that you can put to work immediately for your patients! Offers a problem-based approach that integrates basic science, diagnostic investigations, and therapeutic management in one place for each cardiovascular disease so you can quickly find all of the actionable knowledge you need without flipping from one section to another. Features introductory bulleted highlights in each chapter that present the most pertinent information at a glance. Presents abundant algorithms to expedite clinical decision making. Includes more than 2,000 lavish, high-quality illustrations, color photographs, tables, and ECGs that capture clinical manifestations as they present in practice, and promote readability and retention. Includes 40 new chapters including Inherited Arrhythmia Syndromes, Implantable Cardioverter-Defibrillators and Cardiac Resynchronization Therapy in CHD, Management of the Cyanotic Patient with CHD, Special Problems for the Cardiology Consultant Dealing with Bariatric/Gastric Bypass — and many more — that equip you with all of the latest knowledge. Presents "Special Problem" sections—many new to this edition—that provide practical advice on problems that can be difficult to treat.
The culmination of a lifetime's fascination with humour in all its forms, this book is the first in any language to embrace such an impressive span of authors and such a broad range of topics in French literary humour. In nine wide-ranging chapters Walter Redfern considers diverse writers and topics, including: Diderot, viewed as a laughing philosopher, mainly through his fiction (Les Bijoux indiscrets, Le Neeu de Rameau, and Jacques le fataliste); humourlessness, corraling Rousseau, Sade, the Christian God, and Jean-Pierre Brisset; the aesthete Huysmans, in both his avatars, Symbolist and Naturalist (A Rebours, Sac au dos, and other texts); the dramatic use of parrots by Flaubert, Queneau, and Beckett; Vallès and la blague; exaggeration in Vallès and Céline (Mort à credit and L'Enfant); the fiction, plays, and autobiography of Sartre; bad jokes in Beckett; wordplay in Tournier's fiction (especially Roi des aulnes and Les Météores). Five interleaved 'riffs' on laughter, dreams, black humour, politics, and taste, carry the enquiry into questions of humour outside of the purely French context, enhancing a book that impresses as much with its vivacity of style as with the breadth and depth of its scholarship.
A treatise on Dutch art on par with Vasari's critical history of Italian art, Karel van Mander's Schilder-Boeck (or Book on Picturing) has long been recognized for its critical and historical influence--and yet, until now, no comprehensive account of the book's conception, aims, and impact has been available. In this in-depth analysis of the content and context of Van Mander's work, Walter S. Melion reveals the Schilder-Boeck's central importance to an understanding of northern Renaissance and Baroque art. By interpreting the terminology employed in the Schilder-Boeck, Melion establishes the text's relationship to past and contemporary art theory. Van Mander is seen here developing his critical categories and then applying them to Ancient, Italian, and Netherlandish artists in order to mark changes within a culture and to characterize excellence for each region. Thus Melion demonstrates how Van Mander revised both the structure and critical language of Vasari's Lives to refute the Italian's claims for the superiority of the Tuscan style, and to clarify northern artistic traditions and the concerns of Netherlandish artists. A much needed corrective to the view that Dutch art of the period was lacking in theory, Melion's work offers a compelling account of a sixteenth- and seventeenth-century theoretical and critical perspective and shows how this perspective suggests a rereading of northern art.
The 19th century in France spawned numerous 'fous litteraires, one of them being Jean-Pierre Brisset (1837-1919). An individualist among individualists, he dismantled the existing French tongue, reshaping it to suit his own grandiose purposes, which were to explain afresh the development of human beings (from frogs) and of their language (from croaks). Continuous and ubiquitous punning was a unique feature of his writing. In this study, Redfern examines such themes as the nature of literary madness, the phenomenon of deadpan humour, the role of analogy, and the place of institutional religion in Brisset's creative rewriting of the creation.
Medical Physiology, in its updated 2nd edition, firmly relates molecular and cellular biology to the study of human physiology and disease. Drs. Walter Boron and Emile Boulpaep and a team of leading physiologists present you with practical, accurate coverage, continually emphasizing the clinical implications of the material. Each chapter explains the principles and organization of each body system, while more than 1400 high-quality, full-color line drawings and prominently featured clinical examples clarify every concept. This exceptionally detailed and comprehensive guide to physiology is ideal for a rich, straightforward, state-of-the-art understanding of this essential subject. Quickly review important content using prominent boxes included throughout the text to provide clinical examples of disordered physiology. Master difficult concepts with the use of 800 color drawings that feature balloon captions explaining key processes. Find information easily with the intuitive organization by body system and consistent style. Get up-to-date coverage of physiology with updated text and figures. Access the fully searchable text online at www.StudentConsult.com, along with Webnotes, Image Bank, 150 Self-assessment questions, and 10 physiology animations. Stay current thanks to updated material, including a new chapter on Physiology of Aging and a new section on hemostasis. Gain a clear visual understanding with a revised and updated art program of high-quality, full color line drawings and prominently featured clinical examples.
The scalp and cortex lie like pages of an open book on which the cortex enciphers vast quantities of information and knowledge. They are recorded and analyzed as temporal and spatial patterns in the electroencephalogram and electrocorticogram. This book describes basic tools and concepts needed to measure and decipher the patterns extracted from the EEG and ECoG. This book emphasizes the need for single trial analysis using new methods and paradigms, as well as large, high-density spatial arrays of electrodes for pattern sampling. The deciphered patterns reveal neural mechanisms by which brains process sensory information into precepts and concepts. It describes the brain as a thermodynamic system that uses chemical energy to construct knowledge. The results are intended for use in the search for the neural correlates of intention, attention, perception and learning; in the design of human brain-computer interfaces enabling mental control of machines; and in exploring and explaining the physicochemical foundation of biological intelligence.
This important publication presents new information regarding "Late Phase Allergic (or Inflammatory) Reactions" (LPR). It includes present knowledge on the pathogenesis of LPR in human skin, nose, bronchi, and other organ systems. The book discusses the roles of antibodies, mediators, and cells as well as animal models of LPR. It describes the importance of LPR in the pathogenesis of chronic disease and the possibilities of their pharmacological modulation. The authors discuss clinical conclusions to be drawn from the observation of LPR, such as continuous treatment and immunotherapy. This volume is a useful reference for scientists and clinicians wishing to understand more about the problems of their allergic patients.
Electroencephalography is truly an interdisciplinary endeavor, involving concepts and techniques from a variety of different disciplines. Included are basic physics, neuro physiology, electrophysiology, electrochemistry, electronics, and electrical engineer ing, as well as neurology. Given this interesting and diverse mixture of areas, the train ing of an EEG technician, a neurology resident, or an EEG researcher in the basics of clinical electroencephalography presents an uncommon challenge. In the realm of technology, it is relatively easy to obtain a technically adequate EEG simply by learning to follow a protocol and by correctly setting the various switches on the EEG machine at the right time. But experience has shown that the ability to obtain high-quality EEGs on a routine, day-to-day basis from a wide variety of patients requires understanding and knowledge beyond what is learned by rote. Likewise, knowledge above and beyond what is gained by simple participation in an EEG reading is necessary to correctly and comprehensively interpret the record. Such knowledge comes from an understanding of the basic principles upon which the practice of clinical EEG is founded - principles that derive from the various disciplines cited.
Completely revised and updated, Dermatology covers all the classical and related fields of dermatology, providing a wealth of information on clinical features, pathophysiology, and differential diagnosis. Over 900 color photographs acquaint the reader with a variety of dermatological diseases. Each chapter contains detailed proposals for comprehensive therapy.
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