Gib's Odyssey is the true story of one extraordinary man, Gib Peters, and his solo odyssey along the Intracoastal Waterway from Key West to New York and back while suffering the ravages of Lou Gehrig’s disease (amyotrophic lateral sclerosis, or ALS). On an astonishing six-month voyage, Gib and his boat, Ka-accidentally, encounter everything from an incompetent captain who dives into the water and accidently stabs himself with his knife after wrapping his ship's anchor around one of Ka Ching’s propellers, to the U.S. Coast Guard rushing to stop him from entering an active weapons test zone. At one point, Gib even commences an epic search for his two kittens, Faith and Hope, when they go AWOL at a marina in Atlantic City. All the while, Gib is forced to cope with increasing levels of paralysis, ultimately having to steer the boat home with his feet after losing all use of the muscles in his arms. The book is far from depressing, however. It is the story of Gib's indomitable spirit in the face of death--one that causes him to do acts such as pouring his invented alcoholic drink, the rum-ka-ching directly into his stomach via his feeding tube and getting incredibly drunk one night. Authored by Gib's neurologist, the book is told in Gib's own voice through his correspondence with friends and family as well as the articles he wrote for the Key West Citizen. Part travelogue, part soul-searching meditation, Gib’s Odyssey is the heart-rending story of a man who defiantly resisted the encroachments of a fatal degenerative disease. The odyssey of Gib Peters is a story of a man who left a lasting mark on his community by conquering despair and choosing a life of adventure with the precious time he had left.
This book is a revision, with greatly expanded inclusion criteria, of the 1993 African American Generals and Flag Officers: Biographies of Over 120 Blacks in the United States Military. It offers detailed, career-oriented summaries for men and women who often overcame societal obstacles to become ranking members of the armed forces. Persons from all branches are now included (Army, Navy, Air Force and Marine Corps), as well as the National Guard and Reserves.
The core of this three-volume book deals with damage-associated molecular patterns abbreviated “DAMPs”, which are unique molecules that save life and fight for survival of all organisms on this planet by triggering robust inflammatory/immune defense responses upon any injury, including those caused by pathogens such as viruses and bacteria. However, these molecules also have a dark side: when produced in excess upon severe insults, they can trigger serious human diseases. The three volumes present current understanding of the importance of DAMP-promoted immune responses in the etiopathogenesis of human diseases and explore how this understanding is impacting diagnosis, prognosis, and future treatment. This third volume addresses the potential of DAMPs in clinical practice, as therapeutic targets and therapeutics, by focusing on a description of antigen-related diseases, which are pathogenetically dominated by DAMPs, that is, infectious and autoimmune disorders and allograft rejection (as an undesired function of these molecules), as well as tumor rejection (as the desired function of these molecules). The book is written for professionals from all medical and paramedical disciplines who are interested in the introduction of innovative data from modern inflammation and immunity research into clinical practice. In this sense, the book reflects an approach to translational medicine. The readership will include all practitioners and clinicians, in particular, ICU clinicians, infectiologists, microbiologists, virologists, hematologists, rheumatologists, diabetologists, neurologists, transplantologists, oncologists, and pharmacists. Also available: Damage-Associated Molecular Patterns in Human Diseases - Vol. 1: Injury-Induced Innate Immune Responses; Damage-Associated Molecular Patterns in Human Diseases - Vol. 2: Danger Signals as Diagnostics, Prognostics, and Therapeutic Targets.
After the conclusion of Pontiac's Uprising, frontier trade reopened in 1765. Unfortunately, for the colonists, the renewed activity favored the French in Canada and Illinois and the British traders in Quebec and Montreal. Only three British regiments were assigned to frontier duty, an inadequate number of troops to enforce trade regulations against the French. To keep the peace with local tribes, the British army allowed the French to trade anywhere, while colonial merchants were restricted to army trading posts. Had the army been more astute in protecting colonial interests, colonial merchants might have been more favorable toward paying taxes in support of military efforts. Frontier commerce was a major component of the colonial economy, ranking third in export behind tobacco and rice. The European demand for fashionable broad-brimmed beaver hats was the driving force that created turmoil on the frontier from 1765 to 1768. After the cession of Canada to Britain in 1763, the French obtained half the beaver pelt exports by forcibly diverting them from Quebec to New Orleans and then on to France. This competition hurt wealthy colonial merchants in New York City and Philadelphia, who blamed the British army and set the tone for the coming conflict.
The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.
Containing articles selected from over 900 international journals, this yearbook is devoted to neurology and neurosurgery. Topics covered include: movement disorders; demylinating diseases; behavioural neurology and dementia; neuromuscular diseases; epilepsy; and metabolic disease.
Gib's Odyssey is the true story of one extraordinary man, Gib Peters, and his solo odyssey along the Intracoastal Waterway from Key West to New York and back while suffering the ravages of Lou Gehrig’s disease (amyotrophic lateral sclerosis, or ALS). On an astonishing six-month voyage, Gib and his boat, Ka-accidentally, encounter everything from an incompetent captain who dives into the water and accidently stabs himself with his knife after wrapping his ship's anchor around one of Ka Ching’s propellers, to the U.S. Coast Guard rushing to stop him from entering an active weapons test zone. At one point, Gib even commences an epic search for his two kittens, Faith and Hope, when they go AWOL at a marina in Atlantic City. All the while, Gib is forced to cope with increasing levels of paralysis, ultimately having to steer the boat home with his feet after losing all use of the muscles in his arms. The book is far from depressing, however. It is the story of Gib's indomitable spirit in the face of death--one that causes him to do acts such as pouring his invented alcoholic drink, the rum-ka-ching directly into his stomach via his feeding tube and getting incredibly drunk one night. Authored by Gib's neurologist, the book is told in Gib's own voice through his correspondence with friends and family as well as the articles he wrote for the Key West Citizen. Part travelogue, part soul-searching meditation, Gib’s Odyssey is the heart-rending story of a man who defiantly resisted the encroachments of a fatal degenerative disease. The odyssey of Gib Peters is a story of a man who left a lasting mark on his community by conquering despair and choosing a life of adventure with the precious time he had left.
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