In this pathbreaking bk, the aus draw on more than 40 yrs of research & clinical observations to construct a comprehensive model for the devt. of the interrelated skills involved in lang performance & trace the crucial implications of this model for
This book is intended for anyone who plans, designs and implements software systems, for anyone who is involved with quality assurance, and hence for anyone who is interested in the practicability of modern concepts, methods and tools in the software development process. The book aims at software engineers and at students with specialized interests in the area of software engineering. The reader is expected to be familiar with the fundamental concepts of software engineering. In writing the book, the authors tap years of experience in industrial projects and research work in the development of methods and tools that support the software development process. Perhaps now more than ever, the buzzword "software crisis" serves to alert us that software systems are often error-prone, that significant diffi culties arise in mastering complexity in the production of software systems, and that the acceptance and adequacy of software products is significantly lower than is the case with other technical products. The following goals have been suggested for the improvement of the software development process: • exact fulfillment of user requirements • increased reliability and robustness • greater modularity of both the development process and the product • simple and adequate operation, i. e. , better ergonomics • easy maintainability and extensibility • cost-effective portability • increased reusability of software components • reduced costs for production, operation and maintenance VI Preface Research and development work in the area of software engineering has in creased dramatically in recent years.
The core of this three-volume book deals with damage-associated molecular patterns abbreviated “DAMPs”, which are unique molecules that save life and fight for survival of all organisms on this planet by triggering robust inflammatory/immune defense responses upon any injury, including those caused by pathogens such as viruses and bacteria. However, these molecules also have a dark side: when produced in excess upon severe insults, they can trigger serious human diseases. The three volumes present current understanding of the importance of DAMP-promoted immune responses in the etiopathogenesis of human diseases and explore how this understanding is impacting diagnosis, prognosis, and future treatment. This third volume addresses the potential of DAMPs in clinical practice, as therapeutic targets and therapeutics, by focusing on a description of antigen-related diseases, which are pathogenetically dominated by DAMPs, that is, infectious and autoimmune disorders and allograft rejection (as an undesired function of these molecules), as well as tumor rejection (as the desired function of these molecules). The book is written for professionals from all medical and paramedical disciplines who are interested in the introduction of innovative data from modern inflammation and immunity research into clinical practice. In this sense, the book reflects an approach to translational medicine. The readership will include all practitioners and clinicians, in particular, ICU clinicians, infectiologists, microbiologists, virologists, hematologists, rheumatologists, diabetologists, neurologists, transplantologists, oncologists, and pharmacists. Also available: Damage-Associated Molecular Patterns in Human Diseases - Vol. 1: Injury-Induced Innate Immune Responses; Damage-Associated Molecular Patterns in Human Diseases - Vol. 2: Danger Signals as Diagnostics, Prognostics, and Therapeutic Targets.
This book is intended for anyone who plans, designs and implements software systems, for anyone who is involved with quality assurance, and hence for anyone who is interested in the practicability of modern concepts, methods and tools in the software development process. The book aims at software engineers and at students with specialized interests in the area of software engineering. The reader is expected to be familiar with the fundamental concepts of software engineering. In writing the book, the authors tap years of experience in industrial projects and research work in the development of methods and tools that support the software development process. Perhaps now more than ever, the buzzword "software crisis" serves to alert us that software systems are often error-prone, that significant diffi culties arise in mastering complexity in the production of software systems, and that the acceptance and adequacy of software products is significantly lower than is the case with other technical products. The following goals have been suggested for the improvement of the software development process: • exact fulfillment of user requirements • increased reliability and robustness • greater modularity of both the development process and the product • simple and adequate operation, i. e. , better ergonomics • easy maintainability and extensibility • cost-effective portability • increased reusability of software components • reduced costs for production, operation and maintenance VI Preface Research and development work in the area of software engineering has in creased dramatically in recent years.
In "Warped Factors", original "Star Trek" star Walter Koenig (a.k.a. Ensign Pavel Chekov) provides a fascinating and often riotous chronicle of his life and career. of color photos.
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