This book presents current recommendations for vaccination for pre- and post-exposure prophylaxis in all suitable target populations and groups. It provides immunization guidelines from the Occupational Safety and Health Administration for health care workers and others at occupational risk of exposure and for routine vaccinations by the Immune Practices Advisory Committee of the Centers for Disease Control.;Covering all aspects of the production, testing and applications of Hepatitis B vaccines, this book: lists all available vaccines worldwide; discusses all serological assays in the field; examines how the vaccine was tested in international clinical trials; describes new programmes for universal immunization of infants; and reveals how the vaccine may prevent some forms of hepatocellular carcinoma.;The book should be of interest to: infectious disease specialists, clinical virologists, immunologists, haematologists, oncologists, hepatologists and gastroenterologists, paediatricians, pharmacologists, molecular biologists, biochemists, biotechnologists, genetic engineers, occupational safety administrators and public health specialists; and upper level undergraduate, graduate and medical school students of these disciplines.
Reprint of the original, first published in 1871. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
Revised, updated, and enhanced from cover to cover, the Sixth Edition of Greenfield’s Surgery: Scientific Principles and Practice remains the gold standard text in the field of surgery. It reflects surgery’s rapid changes, new technologies, and innovative techniques, integrating new scientific knowledge with evolving changes in surgical care. Updates to this edition include new editors and contributors, and a greatly enhanced visual presentation. Balancing scientific advances with clinical practice, Greenfield’s Surgery is an invaluable resource for today’s residents and practicing surgeons.
The Fifth International Lymphokine Workshop was convened in Clearwater Beach, Florida, January 11-15, 1987. The theme chosen for the meeting was 'The Molecular Basis of Lymphokine Action," which reflected the opinion of the organizers as to how far the field had moved since the first Lymphokine Workshop only eleven years ago. As was evident at the last Lymphokine Workshop held in 1985, the contribution of molecular biology, particularly in the cloning of lymphokine genes, continues to play an important role in clarifying the structure of lymphokines, providing recombinant (read "pure") proteins for biological studies, and suggesting directions for studies of the molecular basis of lymphokine activity. The most recent lymphokines to yield to molecular cloning meth odology were the B-cell growth and differentiation factors, in partic ular BSF-1 or, as it is sometimes termed, interleukin 4. One of the surprises from this research is the broad spectrum of activities that can be attributed to this molecule, aside from its effects on B-cells, thus perhaps justifying its being called an interleukin. The interleukin 2 symposium demonstrated that even in a well-established research area, controversy and excitement can continue, when evidence was presented by several investigators indicating the presence of a second "converter" protein that changes the affinity of the now classical Tac antigen from a low to a high affinity IL-2 receptor.
Reprint of the original, first published in 1871. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
Until its soldiers mustered out of service in mid-1864, the Pennsylvania Reserve Division was one of only a few one-state divisions in the Union army. Known as the Pennsylvania Reserves, or simply the Reserves, the division saw action in most of the major battles of the Civil War, including Mechanicsville, New Market Crossroads, Second Bull Run, Fredericksburg, Gettysburg, the Wilderness, and Spotsylvania Court House. This history chronicles the division's service from its organization in May 1861 through June 1864, when most of its soldiers reached the end of their service commitment. The book includes short biographical sketches, most with photographs, of the Reserves leadership. Throughout, excerpts from letters, journals, diaries, and books from more than 150 members of the Reserves provide a personal perspective on the action and reveal the human side of battle.
Reprint of the original. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
Now in striking full color, this Seventh Edition of Koneman’s gold standard text presents all the principles and practices readers need for a solid grounding in all aspects of clinical microbiology—bacteriology, mycology, parasitology, and virology. Comprehensive, easy-to-understand, and filled with high quality images, the book covers cell and structure identification in more depth than any other book available. This fully updated Seventh Edition is enhanced by new pedagogy, new clinical scenarios, new photos and illustrations, and all-new instructor and student resources.
A large number of cardiovascular diseases are accompanied by inflammation. This volume on the molecular basis of microcirculatory disorders gives a comprehensive summary of key steps in the inflammatory cascade. Leading investigators present a state-of-the-art analysis of the molecular determinants of leukocyte-endothelial cell adhesion, mechanotransduction in endothelial and inflammatory cells, mechanisms of cell activation, microvascular apoptosis with applications to ischemia-reperfusion in the brain, the heart and in venous disease, diabetes and hypertension. The book provides the latest thinking in these important cardiovascular problems, with the most contemporary literature and a look at the increasingly complex events during inflammation. Molecular biology tools, microvascular and modern bioengineering analysis are seamlessly integrated into the analysis of clinical problems. The book helps not only newcomers to gain entry into the interesting problems associated with microvascular disorders, but lays the foundation for the design of new therapeutic interventions.
Hydrology and Global Environmental Change presents the hydrological contribution to, and consequences of, global environmental change. Assuming little or no prior knowledge on the part of the reader, the book looks at the main processes of global environmental change - global scale processes, large regional processes, repetitive processes - and how the hydrological cycle, processes and regimes impact on GEC and vice-versa.
Edgar Holden, M.D., of Newark: Provincial Physician on a National Stage is a study of medicine and health in Essex County, New Jersey, and its largest city, Newark, in the decades following the Civil War. Th e book is structured around the multifaceted career of Edgar Holden, a Newark physician who transcended the provinciality that characterized Essex County?s medical community and institutions. Th e author demonstrates how institution building and new paradigms of medical authority funneled from burgeoning urban medical centers into the provincial and sluggish medical landscape of northern New Jersey. Th e lack of a medical school within the state stymied the intellectual and professional ferment that the best nineteenth-century American medical schools attracted and fostered. New York City, with its medical institutions and elite practitioners cast a giant shadow over northern New Jersey, which consequently has been somewhat neglected by historians of medicine. An exploration of this lively community of welltrained practitioners, fl edgling institutions, and ailing citizens sheds light on similar medical communities that found themselves importing?but rarely exporting?medical knowledge and expertise.
The bestselling treatment guide, updated to reflect changes to the DSM-5 Selecting Effective Treatmentsprovides a comprehensive resource for clinicians seeking to understand the symptoms and dynamics of mental disorders, in order to provide a range of treatment options based on empirically effective approaches. This new fifth edition has been updated to align with the latest changes to the DSM-5, and covers the latest research to help you draw upon your own therapeutic preferences while constructing an evidence-based treatment plan. Organized for quick navigation, each disorder is detailed following the same format that covers a description, characteristics, assessment tools, effective treatment options, and prognosis, including the type of therapy that is likely to be most successful treating each specific disorder. Updated case studies, treatments, and references clarify the latest DSM-5 diagnostic criteria, and the concise, jargon-free style makes this resource valuable to practitioners, students, and lay people alike. Planning treatment can be the most complicated part of a clinician's job. Mental disorders can be complex, and keeping up with the latest findings and treatment options can itself be a full time job. Selecting Effective Treatments helps simplify and organize the treatment planning process by putting critical information and useful planning strategies at your fingertips Get up to speed on the latest changes to the DSM-5 Conduct evidence-based treatment suited to your therapeutic style Construct Client Maps to flesh out comprehensive treatment plans Utilize assessment methods that reflect the changes to the DSM-5 multiaxial system Effective treatment begins with strategic planning, and it's important to match the intervention to your own strengths, preferences, and style as much as to the client's needs. Selecting Effective Treatments gives you the latest information and crucial background you need to provide the evidence-backed interventions your clients deserve.
The Fourth Edition of Genetics of Populations is the most current, comprehensive, and accessible introduction to the field for advanced undergraduate and graduate students, and researchers in genetics, evolution, conservation, and related fields. In the past several years, interest in the application of population genetics principles to new molecular data has increased greatly, and Dr. Hedrick's new edition exemplifies his commitment to keeping pace with this dynamic area of study. Reorganized to allow students to focus more sharply on key material, the Fourth Edition integrates coverage of theoretical issues with a clear presentation of experimental population genetics and empirical data. Drawing examples from both recent and classic studies, and using a variety of organisms to illustrate the vast developments of population genetics, this text provides students and researchers with the most comprehensive resource in the field.
Health risks are dynamic and ever-changing, both at home and while traveling abroad. To stay abreast of the most up-to-date health recommendations, for decades health care professionals and travelers have relied on the Centers for Disease Control and Prevention's user-friendly Health Information for International Travel (commonly referred to as the The Yellow Book) as a trusted reference. Updated biennially by a team of experts, this book is the only publication for all official government recommendations for international travel. The book's features include clear and easy-to-read disease risk maps, information on where to find health care during travel, specific health information and itineraries for popular tourist destinations, detailed country-specific information for yellow fever and malaria, advice for those traveling with infants and children, and a comprehensive catalog of diseases, their clinical pictures, and their epidemiologies. The Yellow Book addresses the pre-travel consult and provides post-travel clinical guidance on ways to approach common syndromes of returned travelers who are ill.
The second edition of The Diversity of Fishes represents a major revision of the world’s most widely adopted ichthyology textbook. Expanded and updated, the second edition is illustrated throughout with striking color photographs depicting the spectacular evolutionary adaptations of the most ecologically and taxonomically diverse vertebrate group. The text incorporates the latest advances in the biology of fishes, covering taxonomy, anatomy, physiology, biogeography, ecology, and behavior. A new chapter on genetics and molecular ecology of fishes has been added, and conservation is emphasized throughout. Hundreds of new and redrawn illustrations augment readable text, and every chapter has been revised to reflect the discoveries and greater understanding achieved during the past decade. Written by a team of internationally-recognized authorities, the first edition of The Diversity of Fishes was received with enthusiasm and praise, and incorporated into ichthyology and fish biology classes around the globe, at both undergraduate and postgraduate levels. The second edition is a substantial update of an already classic reference and text. Companion resources site This book is accompanied by a resources site: www.wiley.com/go/helfman The site is being constantly updated by the author team and provides: · Related videos selected by the authors · Updates to the book since publication · Instructor resources · A chance to send in feedback
For more than 30 years, Practical Management of Pain has offered expert guidance to both clinicians and trainees, covering every aspect of acute and chronic pain medicine for adult and pediatric patients. The fully revised 6th Edition brings you fully up to date with new developments in patient evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. Edited by a team of renowned pain clinicians led by Dr. Honorio Benzon, this authoritative reference is a comprehensive, practical resource for pain diagnosis and treatment using a variety of pharmacologic and physical modalities. - Presents a wealth of information in a clearly written, easily accessible manner, enabling you to effectively assess and draw up an optimal treatment plan for patients with acute or chronic pain. - Takes a practical, multidisciplinary approach, making key concepts and techniques easier to apply to everyday practice. - Shares the knowledge and expertise of global contributors on all facets of pain management, from general principles to specific management techniques. - Discusses the latest, best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents such as topical analgesics. - Covers recent global developments regarding opioid induced hyperalgesia, neuromodulation and pain management, and identification of specific targets for molecular based pain. - Includes current information on the use of cannabinoids in pain management and related regulatory, professional, and legal considerations. - Includes the latest guidelines on facet injections and safety of contrast agents. - Provides new, evidence-based critical analysis on treatment modality outcomes and the latest information on chronic pain as a result of surgical interventions. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Now with additional review content and a larger page size, The MD Anderson Surgical Oncology Manual, Seventh Edition, focuses on multidisciplinary, cooperative management approaches to issues confronting today’s surgical oncologist. Lead editor Dr. Barry W. Feig is joined by recently graduated surgical oncology fellows Michael G. White, Cameron E. Gaskill, Anai N. Kothari, and Sandra R. DiBrito to bring you comprehensive yet concise information on the complete range of oncologic considerations needed to effectively understand cancer and all aspects of its treatment.
Kendig, Chernick’s Disorders of the Respiratory Tract in Children is the definitive medical reference book to help you confront critical challenges using the latest knowledge and techniques. You’ll get the state-of-the-art answers you need to offer the best care to young patients. Tackle the toughest challenges and improve patient outcomes with coverage of all the common and rare respiratory problems found in newborns and children worldwide. Get a solid foundation of knowledge to better understand and treat your patients through coverage of the latest basic science and its relevance to clinical problems. Get comprehensive, authoritative coverage on today’s hot topics, such as interstitial lung disease, respiratory disorders in the newborn, congenital lung disease, swine flu, genetic testing for disease and the human genome, inflammatory cytokines in the lung, new radiologic techniques, diagnostic imaging of the respiratory tract, and pulmonary function tests. Learn from the experts with contributions from 100 world authorities in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, anesthesiology, otolaryngology, allergy, and surgery.
The authors of this book contend that the civil service system, which was devised to create a uniform process for recruiting high-quality workers to government, is no longer uniform or a system. Nor does it help government find and retain the workers it needs to build a government that works. The current civil service system was designed for a government in which federal agencies directly delivered most public services. But over the last generation, privatization and devolution have increased the number and importance of government's partnerships with private companies, nonprofit organizations, and state and local governments. Government workers today spend much of their time managing these partnerships, not delivering services, and this trend will only accelerate in the future. The authors contend that the current system poorly develops government workers who can effectively manage these partnerships, resulting too often in a gap between promise and performance. This short, lively, and bipartisan volume, authored by the nation's leading experts on government management, describes what the government of the future will look like, what it will need to work well, and how in particular the nation can build the next generation of workers required to lead it.
From Boron Trifluoride to Zinc, the 52 most widely used reagents in organic synthesis are described in this unique desktop reference for every organic chemist. The list of reagents contains classics such as N-Bromosuccinimide (NBS) and Trifluoromethanesulfonic Acid side by side with recently developed ones like Pinacolborane and Tetra-n-propylammonium Perruthenate (TPAP). For each reagent, a concise article provides a brief description of all important reactions for which the reagent is being used, including yields and reaction conditions, an overview of the physical properties of the reagent, its storage conditions, safe handling, laboratory synthesis and purification methods. Advantages and disadvantages of the reagent compared to alternative synthesis methods are also discussed. Reagents have been hand-picked from among the 5000 reagents contained in EROS, the Encyclopedia of Reagents for Organic Synthesis. Every organic chemist should be familiar with these key reagents that can make almost every reaction work.
The rapid pace of technological change is placing the world's telephone companies in a very difficult position. Fiber optics cables, wireless telephones, digital signal compression, and sophisticated new switching equipment are lowering the cost of providing service and opening the gates to new competition. At the same time, these new technologies are providing the telephone companies with a wide array of new market opportunities. Unfortunately, their status as regulated carriers makes it difficult to exploit these new opportunities and to fend off competitive assaults on their traditional telephone business. As long as they are regulated, they can be accused of using their monopoly services to cross-subsidize new competitive ventures. But partial deregulation and open entry would be a catastrophe for them unless they were allowed to revise their rate structure. There is a widespread misconception that the U.S. telecommunications industry has been "deregulated" and that Canadian authorities are following the U.S. lead. In fact, most services remain regulated, even though some markets, such as long-distance services, equipment sales and rentals, and local services, have been opened up. This book reviews the recent changes in the structure of U.S. and Canadian telecommunications industries and the changes in regulatory policy on both sides of the border. The authors analyze the effects of these changes in regulation on telephone rates in both the local and long-distance markets with particular emphasis on the impacts of regulatory reforms and competition on long-distance rates. They use their results to suggest how regulation should be structured to allow competition to replace monopoly on the road to the information superhighway. The authors contend that for decades misguided regulation of the telephone sector in both Canada and the U.S. denied consumers the benefits of competition, distorted local and long-distance telephone rates, and blocked en
Organophosphorus Chemistry provides a comprehensive annual review of the literature. Coverage includes phosphines and their chalcogenides, phosphonium salts, low coordination number phosphorus compounds, penta- and hexa-coordinated compounds, tervalent phosphorus acids, nucleotides and nucleic acids, ylides and related compounds, and phosphazenes. The series will be of value to research workers in universities, government and industrial research organisations, whose work involves the use of organophosphorus compounds. It provides a concise but comprehensive survey of a vast field of study with a wide variety of applications, enabling the reader to rapidly keep abreast of the latest developments in their specialist areas. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Building on the foundation of a one-year introductory course in organic chemistry, Bioorganic Synthesis: An Introduction focuses on organic reactions involved in the biosynthesis of naturally-occurring organic compounds with special emphasis on natural products of pharmacological interest. The book is designed specifically for undergraduate students, rather than as an exhaustive reference work for graduate students or professional researchers and is intended to support undergraduate courses for students majoring in chemistry, biochemistry, biology, pre-medicine, and bioengineering programs who would benefit from a deeper understanding of the chemical logic of reactions carried out in organisms and the origins and uses of the important organic compounds they often produce. The book assumes no prior background in biochemistry and consists of eight chapters: i) a brief review of relevant topics from introductory organic chemistry; ii) presentation of essential organic and biochemical reactions used throughout the book along with a brief introduction to coenzymes; iii) review of basic carbohydrates and the biosynthesis of amino acids; iv) the terpenoid pathway for biosynthesis of all important classes of terpenoids and steroids; v) the acetate pathway for biosynthesis of saturated and unsaturated fatty acids, prostaglandins and acetate-derived polyketide natural products; vi) the biosynthesis of the shikimate pathway products derived from aromatic amino acids; vii) an introduction to biosynthesis of major alkaloids and related nitrogenous compounds; and viii) an overview of laboratory organic synthesis as it relates to the challenges faced by synthetic and medicinal chemists who must recreate intricate natural product structures in the laboratory.
Private liberal arts colleges provide high-quality undergraduate education, but their survival is in doubt. Some see the liberal arts as increasingly irrelevant in a world marked by growing demand for technical training. Others wonder how private colleges, many with few students and high tuitions, can compete successfully against heavily subsidized public colleges and universities. David Breneman, an economist and former college president, explores these and many other educational and economic issues in this book, a detailed analysis of more than 200 liberal arts colleges. Breneman describes the recent financial and curricular history of liberal arts colleges. He explains how they have survived and how many have prospered despite severe competitive pressures. He shows how both outsiders and college administrators themselves misunderstand the role and effects of unfunded student aid (tuition discounting) and how this misunderstanding leads to questionable policies. He shows why the universe of liberal arts colleges—which includes such diverse members as women's colleges, black colleges, religiously affiliated colleges, and highly selective colleges—have had diverse experiences and confront different futures. Breneman includes sketches of twelve colleges that provide insight into both the shared and distinctive concerns of a varied but representative set of liberal arts colleges. He weaves these specific cases into a concluding chapter on the prospects for liberal arts colleges. This book is designed to appeal to college administrators, trustees, faculty, students, alumni, policymakers, and anyone who cares about quality higher education.
Put the world's most well-known kidney reference to work in your practice with the 11th Edition of Brenner & Rector's The Kidney. This two-volume masterwork provides expert, well-illustrated information on everything from basic science and pathophysiology to clinical best practices. Addressing current issues such as new therapies for cardiorenal syndrome, the increased importance of supportive or palliative care in advanced chronic kidney disease, increasing live kidney donation in transplants, and emerging discoveries in stem cell and kidney regeneration, this revised edition prepares you for any clinical challenge you may encounter. - Extensively updated chapters throughout, providing the latest scientific and clinical information from authorities in their respective fields. - Lifespan coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and old age. - Discussions of today's hot topics, including the global increase in acute kidney injury, chronic kidney disease of unknown etiology, cardiovascular disease and renal disease, and global initiatives for alternatives in areas with limited facilities for dialysis or transplant. - New Key Points that represent either new findings or "pearls" of information that are not widely known or understood. - New Clinical Relevance boxes that highlight the information you must know during a patient visit, such as pertinent physiology or pathophysiology. - Hundreds of full-color, high-quality photographs as well as carefully chosen figures, algorithms, and tables that illustrate essential concepts, nuances of clinical presentation and technique, and clinical decision making. - A new editor who is a world-renowned expert in global health and nephrology care in underserved populations, Dr. Valerie A. Luyckx from University of Zürich. - Board review-style questions to help you prepare for certification or recertification. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
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