The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra. This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications. Mass Spectrometry, Third Edition is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine, pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments.
This book provides a rigorous and self-contained review of desingularization theory. Focusing on arbitrary dimensional schemes, it discusses the important concepts in full generality, complete with proofs, and includes an introduction to the basis of Hironaka’s Theory. The core of the book is a complete proof of desingularization of surfaces; despite being well-known, this result was no more than folklore for many years, with no existing references. Throughout the book there are numerous computations on standard bases, blowing ups and characteristic polyhedra, which will be a source of inspiration for experts exploring bigger dimensions. Beginners will also benefit from a section which presents some easily overlooked pathologies.
Cardiovascular Imaging, a title in the Expert Radiology Series, edited by Drs. Vincent Ho and Gautham P. Reddy, is a comprehensive 2-volume reference that covers the latest advances in this specialty. It provides richly illustrated, advanced guidance to help you overcome the full range of diagnostic, therapeutic, and interventional challenges in cardiovascular imaging and combines an image-rich, easy-to-use format with the greater depth that experienced practitioners need. Online access at www.expertconsult.com allows you to rapidly search for images and quickly locate the answers to any questions. - Access the fully searchable text online at www.expertconsult.com, along with downloadable images. - View 5000 full-color digital images of both radiographic images and cutting-edge modalities—MR, multislice CT, ultrasonography, and nuclear medicine. - Tap into comprehensive coverage that includes diagnostic and therapeutic options, with an emphasis on cost-effective imaging. - Consult the experience of a diverse group of experts on cardiovascular imaging from around the globe. - Find information quickly and easily thanks to consistent and tightly focused chapters, a full-color design, and key points boxes.
An interval is the distance between two notes measured in whole and half steps. When we stack intervals one on top of another, we produce chords. If we play the intervals in the chord one after another, we produce an arpeggio. But since all intervals, chords, and arpeggios are generated by scales, it follows that scales are the basis of all music from these scales we will find our JAZZ LINES, which is what this book is about. The following is a list of most of the jazz scales the student will encounter as he becomes involved in the study of improvising. When we improvise, we use as our weapons the scale, harmony and melody. The two dimensions in music are the harmony (vertical) and melody (horizontal). It is highly recommended that every student of improvising, know his scales in all positions and a variety of chords that the scales generate. All scales should be played in at least four positions especially the 1st position forces one to learn the theory. All other position pattern scales must be transposed throughout the guitar. The author has written a few pages in the beginning of the book serving as a prerequisite for the jazz lines to follow. It is essential that the student know the scales, key signatures, intervals, and chord constructions that will be used throughout the book. In order to benefit fully from this approach to jazz, the student must understand the full meaning of the words practice and analysis. Most students confuse practice with playing or reading through the exercise. To really improve and absorb the material, every phase must be practiced. This means the fingering must be committed to memory, slowly at first and then as fast as technique allows. The idea must be so ingrained in the mind that it flows from any part of the fingerboard that the performer desires. This is the way great players approach an idea – from any fret, string or position! If there is no harmonic or melodic analysis of the material being studied, then the learning skill becomes superfluous and there is no comprehension and absorption, and without this proper digestion the performer cannot use it as his taste dictates. All of the great players, have had a great technique and this is the first goal of the young student – “great chops.” As the student matures, musicianship will grow but technique is at the grasp of all who seek it. Start today to acquire it!
Quinolones constitute a large class of synthetic antimicrobial agents that are highly effective in the treatment of many types of infectious diseases, particularly those caused by bacteria. New quinolones are continually being developed as bacterial species develop resistance to existing quinolones. This book presents the most current information available in our continual struggle to conquer disease. Over time, bacteria become resistant to medicines that are used to combat them. Because of this, the medical world is always in search of new and improved ways to battle these disease-causing bacteria. Quinolones are at the forefront of this research. Edited by one of the world's foremost authorities on the subject, the third edition of this highly successful title will serve as a valuable tool for primary care physicians and researchers interested in a comprehensive, up-to-date reference on the chemistry, mechanisms of action, development of resistance, and clinical efficacy of both currently available and newer quinolone compounds under investigation. This is the eagerly anticipated fully revised edition of the standard reference in the field. - Eagerly anticipated updated edition of noted title covering synthetic microbial agents that are useful against infectious disease, particularly those caused by bacteria - Edited by one of the foremost experts in the field of quinolone research and infectious disease - History of quinolones, chemistry & mechanisms of action, pharmacology, safety aspects - Role of quinolones in treating various types of infections, including respiratory infections, gastrointestinal infections, urinary tract infections, prostatitis, STDs and bacterial meningitis as well as their use in immunocompromised patients
The integration of top-down lithographic techniques with synthetic organic and inorganic technologies is a key challenge for the development of effective nanosca1e devices. In terms of assembly, nanoparticles provide an excellent tool for bridging the gap between the resolution of electron beam lithography (-60 nm) and the molecular level. Nanoparticles possess an array of unique properties associated with their core materials, including distinctive magnetic, photonic and electronic behavior. This behavior can be controlled and applied through monolayer functionalization and assembly strategies, making nanoparticles both scaffolds and building blocks for nanotechnology. The diverse structures and properties of nanoparticles makes them useful tools for both fundamental studies and pragmatic applications in a range of disciplines. This volume is intended to provide an integrated overview of the synthesis and assembly of nanoparticles, and their applications in chemistry, biology, and materials science. The first three chapters focus on the creation and intrinsic properties of nanoparticles, covering some of the myriad core materials and shapes that have been created. The remaining chapters of the book discuss the assembly of nanoparticles, and applications of both discrete particles and particle assemblies in a wide range of fields, including device and sensor fabrication, catalysis, biology, and nanosca1e electronic and magnetic systems.
This book walks students through the selection and application of research methods within Tourism. Experienced authors introduce the relevant language and theory of key methodologies and then develop them using strategic literature review and the inclusion of international examples which relate directly to tourism. Each concept sets the historical and philosophical context of a method alongside the practical application of the technique and provides: • authoritative and reliable data • informative cross-referencing • detailed discussion of theories and their critics • suggestions for further reading The book is a vital resource for all students of tourism, leisure and management.
The Yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in their field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine. (With approximately 90 contributions.)
Based on the successful format of AO courses, this two-volume reference is a comprehensive manual for the latest AO spine techniques. For each case, the book guides the reader from case presentation, through rationale for surgical treatment, and to non-operative treatment options. The authors describe potential complications in spine surgery and outcomes. Volume I,Principles and Techniques, begins with a complete review of basic science concepts, helping the reader understand the biomechanics, biology, and the surgical anatomy of the spine. This volume provides a systematic overview of spinal instrumentation, computer-assisted surgery, and anesthesia considerations. Volume II, Clinical Applications, presents a compilation of clinical cases addressing the most common spinal problems, such as spinal trauma, tumors, infections, inflammatory processes, deformities, degenerative spinal diseases, and metabolic bone disease. Throughout both volumes, high-quality photographs and drawings illustrate surgical techniques step-by-step and demonstrate key concepts of management. Clear, easy-to-reference bulleted lists and shaded text boxes facilitate rapid review of important learning points. An accompanying DVD-ROM with video clips from live surgery symposia and practical exercises also enhance the readers learning experience.
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