The incidence of developing infection in prosthetic joints remains low after primary arthroplasty, but owing to the growing success of joint replacement surgery as a procedure to alleviate pain and improve mobility, infection numbers are increasing. The impact on the patient is immense, and surgical options are challenging. Prevention and reducing the incidence is the key to addressing this problem. Pathways in Prosthetic Joint Infection covers the most common incidences where the risk of PJI is elevated (such as following revision arthroplasty), and indicates suitable approaches to aid the improvement of outcomes. Featuring clearly-illustrated clinical cases on the typical presentation of established and latent infections, the microbiology profiles, assessment, and definitive management are all highlighted. Taking a team-based approach that includes the ortho-plastic surgery team, physiotherapists, and microbiologists, this new book provides a concise summary of the current literature and an essential overview of the management options for those with PJI. Endorsed by the Royal College of Surgeons, BAPRAS, The Vascular Society, and BASK, Pathways in Prosthetic Joint Infection is an indispensable title for all those working with patients who may face PJI.
This book is recommended for anyone wanting to quickly get up to speed with oceans governance, bearing in mind at this stage it is an immature and quickly developing field. The strength of the book is that it is grounded in real-world examples from four case study countries and in this context at the very least exposes the reader to emergent oceans governance and policy issues. . . an excellent starting point for further analysis of oceans governance and sets up a research agenda for the future.' - Murray Patterson, Journal of Ecological Economics
Why did the US intelligence services fail so spectacularly to know about the Soviet Union's nuclear capabilities following World War II? As Vince Houghton, historian and curator of the International Spy Museum in Washington, DC, shows us, that disastrous failure came just a few years after the Manhattan Project's intelligence team had penetrated the Third Reich and knew every detail of the Nazi 's plan for an atomic bomb. What changed and what went wrong? Houghton's delightful retelling of this fascinating case of American spy ineffectiveness in the then new field of scientific intelligence provides us with a new look at the early years of the Cold War. During that time, scientific intelligence quickly grew to become a significant portion of the CIA budget as it struggled to contend with the incredible advance in weapons and other scientific discoveries immediately after World War II. As The Nuclear Spies shows, the abilities of the Soviet Union's scientists, its research facilities and laboratories, and its educational system became a key consideration for the CIA in assessing the threat level of its most potent foe. Sadly, for the CIA scientific intelligence was extremely difficult to do well. For when the Soviet Union detonated its first atomic bomb in 1949, no one in the American intelligence services saw it coming.
A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.
Personal robots are about as advanced today as personal computers were on the eve of the first IBM PC in the early 1980s. They are still the domain of hobbyists who cobble them together from scratch or from kits, join local clubs to swap code and stage contests, and whose labor of love is setting the stage for a technological revolution. This book will deconstruct the 30 regional winning robot designs from the FIRST Robotics Competition in 2006. The FIRST Robotics Competition (held annually and co-founded by Dean Kamen and Woodie Flowers) is a multinational competition that teams professionals and young people to solve an engineering design problem in an intense and competitive way. In 2005 the competition reached close to 25,000 people on close to 1,000 teams in 30 competitions. Teams came from Brazil, Canada, Ecuador, Israel, Mexico, the U.K., and almost every U.S. state. The competitions are high-tech spectator sporting events that have gained a loyal following because of the high caliber work featured. Each team is paired with a mentor from such companies as Apple, Motorola, or NASA (NASA has sponsored 200 teams in 8 years). This book looks at 30 different robot designs all based on the same chassis, and provides in-depth information on the inspiration and the technology that went into building each of them. Each robot is featured in 6-8 pages providing readers with a solid understanding of how the robot was conceived and built. There are sketches, interim drawings, and process shots for each robot.
The incidence of developing infection in prosthetic joints remains low after primary arthroplasty, but owing to the growing success of joint replacement surgery as a procedure to alleviate pain and improve mobility, infection numbers are increasing. The impact on the patient is immense, and surgical options are challenging. Prevention and reducing the incidence is the key to addressing this problem. Pathways in Prosthetic Joint Infection covers the most common incidences where the risk of PJI is elevated (such as following revision arthroplasty), and indicates suitable approaches to aid the improvement of outcomes. Featuring clearly-illustrated clinical cases on the typical presentation of established and latent infections, the microbiology profiles, assessment, and definitive management are all highlighted. Taking a team-based approach that includes the ortho-plastic surgery team, physiotherapists, and microbiologists, this new book provides a concise summary of the current literature and an essential overview of the management options for those with PJI. Endorsed by the Royal College of Surgeons, BAPRAS, The Vascular Society, and BASK, Pathways in Prosthetic Joint Infection is an indispensable title for all those working with patients who may face PJI.
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