An astonishingly candid memoir from the acclaimed, dissident playwright elected President after the dramatic Czechoslovakian Velvet Revolution — one of the most respected political figures of our time. As writer and statesman, Václav Havel played an essential part in the profound changes that occurred in Central Europe in the last decades of the twentieth century. In this most intimate memoir, he writes about his transition from outspoken dissident and political prisoner to a player on the international stage in 1989 as newly elected president of Czechoslovakia after the ousting of the Soviet Union, and, in l993, as president of the newly formed Czech Republic. Havel gives full rein to his impassioned stance against the devastation wrought by communism, but the scope of his concern in this engrossing memoir extends far beyond the circumstances he faced in his own country. The book is full of anecdotes of his interactions with world figures: offering a peace pipe to Mikhail Gorbachev, meditating with the Dali Lama, confessing to Pope John Paul II and partying with Bill and Hilary Clinton. Havel shares his thoughts on the future of the European Union and the role of national identity in today’s world. He explains why he has come to change his mind about the war in Iraq, and he discusses the political and personal reverberations he faces because of his initial support of the invasion. He writes with equal intelligence and candour about subjects as diverse as the arrogance of western power politics, the death of his first wife and his own battle with lung cancer. Woven through are internal memos he wrote during his presidency that take us behind the scenes of the Prague Castle – the government’s seat of power – showing the internal workings of the office and revealing Havel’s mission to act as his country’s conscience, and even, at times, its chief social convenor. Written with characteristic eloquence, wit and well-honed irony combined with an unfailing sense of wonder at the course his life has taken, To the Castle and Back is a revelation of one of the most important political figures of our time.
In this new book, President Klaus examines the uneasy Europe of today, without illusions or personal attacks, but with a mercilessly realistic view of the system that Europe has created in the last half century. He examines the benefits of integrating the continent in strictly economic terms and explains the tragic flaw in the original plan to do so.
The first book-length appearance of Václav Cílek's work in English translation, To Breathe with Birds delves into the imaginative and emotional bonds we form with landscapes and how human existence—a recent development, geologically speaking—shapes and is shaped by a sense of place.
Immune System Accessory Cells provides a comprehensive survey of all types of antigen-presenting and accessory cells. Macrophages are emphasized through descriptions of different types of endocytosis, other major properties, and all basic and new information concerning macrophages as antigen-presenting cells. Other topics covered include the impact of the immunodeficient state on accessory functions, the evolutionary emergence of accessory functions, and the role of various cell types in defense reactions in major assemblages of Metazoa. The book also presents a chapter describing the phylogenetic aspects of accessory functions, which traces the first accessory cells during the evolution of living matter. Immune System Accessory Cells is an excellent reference for immunologists, cell biologists, and others interested in developing an understanding of the roles of accessory cells in all facets of immune reactions.
First published in 1990. This exciting volume provides an in-depth look at all of the aspects of fetal well-being. It bases each chapter on a critical evaluation of medical literature and on the authors' clinical experience regarding the subject. Easy to read and understand, this book presents discussions on the anatomical structure and respiratory function of the placenta and their effects on the fetus. The 67 figures illustrate theoretical concepts and clinical applications, and the conveniently placed tables allow speedy access to precise data throughout the text. This publication gives special consideration to the developments in ultrasound and direct access to the fetus. Every person involved with obstetrics, gynecology, reproductive medicine, pediatrics, and ultrasound will consider this monograph a must.
This inquiry into the technical advances that shaped the 20th century follows the evolutions of all the principal innovations introduced before 1913 (as detailed in the first volume) as well as the origins and elaborations of all fundamental 20th century advances. The history of the 20th century is rooted in amazing technical advances of 1871-1913, but the century differs so remarkably from the preceding 100 years because of several unprecedented combinations. The 20th century had followed on the path defined during the half century preceding the beginning of World War I, but it has traveled along that path at a very different pace, with different ambitions and intents. The new century's developments elevated both the magnitudes of output and the spatial distribution of mass industrial production and to new and, in many ways, virtually incomparable levels. Twentieth century science and engineering conquered and perfected a number of fundamental challenges which remained unresolved before 1913, and which to many critics appeared insoluble. This book is organized in topical chapters dealing with electricity, engines, materials and syntheses, and information techniques. It concludes with an extended examination of contradictory consequences of our admirable technical progress by confronting the accomplishments and perils of systems that brought liberating simplicity as well as overwhelming complexity, that created unprecedented affluence and equally unprecedented economic gaps, that greatly increased both our security and fears as well as our understanding and ignorance, and that provided the means for greater protection of the biosphere while concurrently undermining some of the key biophysical foundations of life on Earth. Transforming the Twentieth Century will offer a wide-ranging interdisciplinary appreciation of the undeniable technical foundations of the modern world as well as a multitude of welcome and worrisome consequences of these developments. It will combine scientific rigor with accessible writing, thoroughly illustrated by a large number of appropriate images that will include historical photographs and revealing charts of long-term trends.
Immunological Disorders in Mice focuses on immunological reactions and diseases based on models provided through studies on genetically based immunological disorders in inbred strains of mice. The book discusses various defects affecting all levels of immunological response, featuring new data on "classical" mutations, as well as information regarding lesser known immune defects. New areas presented include genetic manipulation, ontogenetic aspects, clinical implications, the effect of drugs on immunodefective strains, and neuroendocrine regulation. A critical evaluation of the data presented through these studies on immune disorders in mice will facilitate the understanding of immunological processes and have significant application in clinical practice. Theoretical immunologists, animal breeding companies, and clinical immunologists will find this text invaluable.
This book on phylogeny and immunity reconstructs the history and evolutionary pathways of immunity among the various forms of life. The authors argue that the immunity could have evolved different adequately successful patterns in the animal sub-regnum which are strictly determined by the morpho-physiological possibilities of the animals. They state that the vertebrate type of immunity evolved only in the chordate branch. The publication devotes special attention to the arthropods and molluscs, as they have attracted more investigative efforts than any other invertebrate taxa. The authors selected Agnatha, Chondrichthyes, and Osteichthyes from the vertebrate taxa in order to show where and how the morphofunctional basis of the truly adapative immunity of the endothermic tetrapods gradually evolved. Each chapter gives the description of the origin and interrelationships of the representatives of the taxon in question. Also given are the main biological, morphological, non-morphological and immune attributes. Emphasized throughout the book is the central idea that immunological reactions are a part of the overall biological phenomena and should be studied only from this aspect. The authors express that the fields of comparative and evolutionary immunology will provide inspiration for further investigations in biomedicine in the near future.
In this new book, President Klaus examines the uneasy Europe of today, without illusions or personal attacks, but with a mercilessly realistic view of the system that Europe has created in the last half century. He examines the benefits of integrating the continent in strictly economic terms and explains the tragic flaw in the original plan to do so.
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