A landmark of 20th Century literature about New York in the late 1960s, now in English for the first time. Late in 1967, Uwe Johnson set out to write a book that would take the unusual form of a chapter for every day of the ongoing year. It would be the tale of Gesine Cresspahl, a thirty-four-year-old single mother who is a German émigré to Manhattan’s Upper West Side, and of her ten-year-old daughter, Marie—a story of work and school, of friends and lovers and the countless small encounters with neighbors and strangers that make up big-city life. An everyday tale, but also a tale of the events of the day, as gleaned by Gesine from The New York Times: Johnson could hardly foresee the convulsions of 1968, but some of the news—the racial unrest roiling America, the escalating war in Vietnam—was sure to be news for some time yet to come. Finally, it would be a tale told by Gesine to Marie about Gesine’s childhood in a small north German town, of her independent and enterprising father, of her troubled mother, of Nazi Germany (Gesine was born the year Hitler came to power) and World War II and Soviet retribution and the grimly regulated realities of Communist East Germany. An ambitious historical novel as well as a wonderfully observed New York novel, Anniversaries would take in the unsettled world of the present along with the twentieth century’s disastrous past, while vividly depicting the struggle of a loving, though hardly uncomplicated mother and a bright, indomitably curious girl to understand and care for each other and to shape a human world. Gesine and Marie are among the most memorable and engaging characters in literature, and Anniversaries, at once monumental and intimate, sweeping and full of incident, stylistically adventurous and endlessly absorbing, is quite simply one of the great books of our time.
Advances in Spinal Fusion reveals a new generation of materials and devices for enhanced operations in spinal fusion. This reference showcases emerging research and technologies in areas such as biodegradable implants, drug delivery, stem cell isolation and transfection, cell encapsulation and immobilization, and the design of 2D and 3D scaffolds for cells. It captures a cascade of innovations crucial to increased healing and decreased morbidity in spinal fusion methods and mechanics and addresses current standards in analytical methodology and quality control, it describes the selection of biomaterials for improved biocompatibility, biostability, and structure/function relationships.
This book provides a thorough critical overview of the current debate on the ethics of war, as well as a modern just war theory that can give practical action-guidance by recognizing and explaining the moral force of widely accepted law. Traditionalist, Walzerian, and "revisionist" approaches have dominated contemporary debates about the classical jus ad bellum and jus in bello requirements in just war theory. In this book, Uwe Steinhoff corrects widely spread misinterpretations of these competing views and spells out the implications for the ethics of war. His approach is unique in that it complements the usual analysis in terms of self-defense with an emphasis on the importance of other justifications that are often lumped together under the heading of "lesser evil." It also draws on criminal law and legal scholarship, which has been largely ignored by just war theorists. Ultimately, Steinhoff rejects arguments in favor of "moral fundamentalism"— the view that the laws and customs of war must simply follow an immutable morality. In contrast, he argues that widely accepted laws and conventions of war are partly constitutive of the moral rules that apply in a conflict. The Ethics of War and the Force of Law will be of interest to scholars and advanced students working in just war theory, applied ethics, political philosophy, political theory, philosophy of law, and criminal and military law.
An evidence-based guide to using cannabis to enhance pain relief safely, effectively, and economically while reducing the risks of opioid addiction Opioid addiction has exploded to epidemic proportions in the U.S. Drug overdose is now the leading cause of accidental death. In 2012, 259 million prescriptions were written for opioids—more than enough to give every American adult their own bottle of pills. Uwe Blesching, author of The Cannabis Health Index, clearly and thoroughly lays out the overwhelming benefits of using cannabis—not only to reduce the nation’s dependence on opioids—but also to manage the craving and withdrawal symptoms of opioid addiction, and especially to address the pain that leads to drug use and addiction in the first place. Citing statistics showing that states allowing legal access to cannabis have seen a 25 percent drop in opioid-related deaths, Blesching explains how precision applications of cannabis can alleviate the mental and emotional aspects of pain by modulating numerous neurotransmitters and their emotional counterparts. He presents a convincing case for the powerful benefits of cannabis in reducing the risks of addiction and overdose, cutting monetary costs, and restoring a sense of balance and control to those who struggle with pain.
Adler and Gielen developed this volume to add the voices of a prominent international group of cross-culturally oriented psychologists to the worldwide debate on migration. Contributors to the book analyze worldwide configurations of migration, fundamental psychosocial factors involved in immigration and emigration, and patterns of migration from and to 16 nations and regions around the globe. The richly varied contributions focus on immigration to the United States from areas as varied as Mexico, the Caribbean, and Ireland, migrations in Colombia, immigrant families in Germany, Poland, and Norway, and migration from and into Japan, South Africa, Egypt, Israel, Australia, and the Phillippines. Of particular interest to scholars, students, and other researchers involved with migration, ethnic groups, and international psychology.
The authors have synthesized 16 years of geological and geophysical studies which document an 85-km-wide impact crater buried 500 m beneath Chesapeake Bay in south eastern Virginia, USA. In doing so, they have integrated extensive seismic reflection profiling and deep core drilling to analyze the structure, morphology, gravimetrics, sedimentology, petrology, geochemistry, and paleontology of this submarine structure. Of special interest are a detailed comparison with other terrestrial and extraterrestrial craters, as well as a conceptual model and computer simulation of the impact. The extensive illustrations encompass more than 150 line drawings and core photographs.
This volume contains a collection of papers all concerned with the exploration of economic and social dynamics in relation to the innovation process and its outcomes. This theme is firmly rooted in the Schumpeterian tradition in which an economic perspective is mutually embedded in a wider awareness of the role of other disciplines. Indeed since Schumpeter's time, the degree of specialisation within the social sciences has risen many fold, new sub disciplines continue to emerge, highly specialised theoretical tools and empirical methods continue to be developed, and new fields for the study of management and business overlap with the more traditional social sciences. There is, consequently, a need for connecting principles to offset the dangers of intellectual fragmentation. Evolutionary economics and evolutionary analysis more generally, certainly provide some of these connecting principles. The various contributions to this volume reflect upon this research programme in a number of ways.
This volume offers a new, synthetic overview of the structure and ritual shape of the Roman Mass from its formative period in late antiquity to its post-Tridentine standarisation. Starting with the Last Supper and the origins of the Eucharist, Uwe Michael Lang constructs a narrative that explores the intense religious, social, and cultural transformations that shaped the Roman Mass. Lang unites classical liturgical history with insights from a variety of other disciplines that have drawn attention to the ritual performance and reception of the mass. He also presents liturgical developments within the broader historical and theological contexts that affected the celebration and experience of the sacramental rite that is still at the heart of Catholic Christianity. Aimed at scholars from a broad swathe of subjects, including religious studies, history, art history, literature, and music, Lang's volume serves as a comprehensive history of the Roman Mass over the course of a millenium.
This book is about the institutions, incentives and constraints that guide the behaviour of people and organizations involved in the implementation of foreign aid programmes. While traditional performance studies tend to focus almost exclusively on the policies and institutions in recipient countries, this book looks at incentives in the entire chain of organizations involved in the delivery of foreign aid, from donor governments and agencies to consultants, experts and other intermediaries. Four aspects of foreign aid delivery are examined in detail: incentives inside donor agencies, the interaction of subcontractors with recipient organizations, incentives inside recipient country institutions, and biases in aid performance monitoring systems.
This book examines the lawmaking bodies of the United states and the Germany and their constitutional duties and limitations. It is a first ever joint US-German parliamentary study that compares and contrasts two of the democratic West's most powerful legislatures.
The International System of Units (SI) is the world's most widely used system of measurement, used every day in commerce and science, and is the modern form of the metric system. It currently comprises the meter (m), the kilogram (kg), the second (s), the ampere (A), the kelvin (K), the candela (cd) and the mole (mol)). The system is changing though, units and unit definitions are modified through international agreements as the technology of measurement progresses, and as the precision of measurements improves. The SI is now being redefined based on constants of nature and their realization by quantum standards. Therefore, the underlying physics and technologies will receive increasing interest, and not only in the metrology community but in all fields of science. This book introduces and explains the applications of modern physics concepts to metrology, the science and the applications of measurements. A special focus is made on the use of quantum standards for the realization of the forthcoming new SI (the international system of units). The basic physical phenomena are introduced on a level which provides comprehensive information for the experienced reader but also provides a guide for a more intense study of these phenomena for students.
Continuing to be THE guide to the whole qualitative research process for students, this book looks at both the theory behind qualitative research and how to put it into practice in your own work. For students across a range of social science disciplines and beyond, this is a must to help you enhance your research project. This edition introduces: a decolonisation of methodologies a range of indigenous, queer and feminist perspectives on methodologies assistance with defending a viva and alternative forms of assessment to suit a changing world. More additions to this seventh edition include a section on the subjectivity of a researcher, and how your identity will shape your research. The further reading has been curated to include more than just western voices, providing you with global perspectives on qualitative research. This text introduces how to sensitively undertake ethical and inclusive research with marginalised groups. This book will help you master a comprehensive understanding of qualitative research.
The International System of Units, the SI, provides the foundation for all measurements in science, engineering, economics, and society. The SI has been fundamentally revised in 2019. The new SI is a universal and highly stable unit system based on invariable constants of nature. Its implementation rests on quantum metrology and quantum standards, which base measurements on the manipulation and counting of single quantum objects, such as electrons, photons, ions, and flux quanta. This book explains and illustrates the new SI, its impact on measurements, and the quantum metrology and quantum technology behind it. The book is based on the book ?Quantum Metrology: Foundation of Units and Measurements? by the same authors. From the contents: -Measurement -The SI (Système International d?Unités) -Realization of the SI Second: Thermal Beam Cs Clock, Laser Cooling, and the Cs Fountain Clock -Flux Quanta, Josephson Effect, and the SI Volt -Quantum Hall Effect, the SI Ohm, and the SI Farad -Single-Charge Transfer Devices and the SI Ampere -The SI Kilogram, the Mole, and the Planck constant -The SI Kelvin and the Boltzmann Constant -Beyond the present SI: Optical Clocks and Quantum Radiometry -Outlook
This book shows you not just how to use triangulation as a strategy of quality management, but also how to use it as an approach to designing and doing qualitative research in a more comprehensive way. Flick links triangulation with current debates about using mixed methods, and outlines their potential for extending qualitative research, addressing questions such as how such research can benefit from integrating quantitative (mixed methods), or from working more generally with more than one approach (triangulation).
This textbook is designed for advanced (graduate and postgraduate) students, and will also be of interest to scholars. It blends a cognitive linguistic approach to language and language use with insights from contemporary pragmatics, the ultimate aim being to advance a unified model of cognitive pragmatics. Basic themes in cognitive linguistics and pragmatics are covered ranging from figurative language and thought, e.g. conceptual metaphor and metonymy, the role of inferencing in the construction of meaning, in particular, indirect speech acts, to the conceptual and functional motivation of morphosyntactic structure. Finally, the book offers many suggestions and ideas for student papers as well as larger research projects that promise to reveal new insights into conceptual structure, communicative function, and their influence on the grammatical structure of language.
Discover best practices for real world data research with SAS code and examples Real world health care data is common and growing in use with sources such as observational studies, patient registries, electronic medical record databases, insurance healthcare claims databases, as well as data from pragmatic trials. This data serves as the basis for the growing use of real world evidence in medical decision-making. However, the data itself is not evidence. Analytical methods must be used to turn real world data into valid and meaningful evidence. Real World Health Care Data Analysis: Causal Methods and Implementation Using SAS brings together best practices for causal comparative effectiveness analyses based on real world data in a single location and provides SAS code and examples to make the analyses relatively easy and efficient. The book focuses on analytic methods adjusted for time-independent confounding, which are useful when comparing the effect of different potential interventions on some outcome of interest when there is no randomization. These methods include: propensity score matching, stratification methods, weighting methods, regression methods, and approaches that combine and average across these methods methods for comparing two interventions as well as comparisons between three or more interventions algorithms for personalized medicine sensitivity analyses for unmeasured confounding
Uwe Kischel's comprehensive treatise on comparative law offers a critical introduction to the central tenets of comparative legal scholarship. The first part of the book is dedicated to general aspects of comparative law. The controversial question of methods, in particular, is addressed by explaining and discussing different approaches, and by developing a contextual approach that seeks to engage with real-world issues and takes a practical perspective on contemporary comparative legal scholarship. The second part of the book offers a detailed treatment of the major legal contexts across the globe, including common law, civil law systems (based on Germany and France, and extended to Eastern Europe, Scandinavia, and Latin America, among others), the African context (with an emphasis on customary law), different contexts in Asia, Islamic law and law in Islamic countries (plus a brief treatment of Jewish law and canon law), and transnational contexts (public international law, European Union law, and lex mercatoria). The book offers a coherent treatment of global legal systems that aims not only to describe their varying norms and legal institutions but to propose a better way of seeking to understand how the overall context of legal systems influences legal thinking and legal practice.
This manual provides an overview of the techniques used in modern neuroscience research. The emphasis is on showing how different techniques can optimally be combined in the study of problems that arise at some levels of nervous system organization. It is a working tool for the scientist in the laboratory and clinic, providing detailed step-by-step protocols with tips and recommendations. Most chapters or protocols are organized such that they can be used independently of one another. Cross-references between the chapters, a glossary, a list of suppliers and appendices provide further help.
The collected papers in this volume are all concerned either in a direct sense or in a more wider perspective with the work of Joseph A. Schumpeter. Looking at Schumpeter's work, his lasting influence on important areas of research can be identified. One of these areas is obviously Schumpeter's idea about the future capitalism, a second one the issue of innovation and its consequences for economic development. A third area is concerned with the political process and the role of political leadership. The collection of this volume is developed along these main lines, complemented by papers discussing the place of Schumpeter's work within the history of economic analysis.
′Flick′s argumentation in this book is convincing. It provides a good overview of the problems of quality assessment in qualitative research and makes constructive suggestions about how to deal with them′ - Thomas S. Eberle, University of St Gallen, Switzerland. The issue of quality in qualitative research is one that is often neglected. In Managing Quality in Qualitative Research attention is given to the fundamental question of how to define and assess the quality of research. Uwe Flick examines how to distinguish good research from bad research when it comes to teaching, planning, evaluating and publishing qualitative research.
Natural and Synthetic Waxes A compilation of all relevant information for the production and use of waxes in technical applications Waxes are among the oldest organic substances used by mankind. Before all others, beeswax is known to have played a role in human history for thousands of years. But over time, many other wax species have been detected and exploited, and prepared for different utilizations. Today, we possess knowledge of a great variety of different types of waxes. Unfortunately, there still is no broadly accepted definition of a wax: for the relatively few wax chemists, waxes are usually defined by their physico-chemical properties more than by their chemical constitution. Waxes are not uniform but oligomeric and polymeric substances, not simply describable with a chemical formula. The realm of waxes encompasses fully or partly natural, refined, partly or fully synthetic products, which can be extended by “wax-like” products which do not fulfil all definition criteria. Waxes are offered in different forms like pellets, granules, powders, or micropowders. Their number of technical applications runs into thousands. However, waxes in most cases are just adjuvants or additives, and with few exceptions like candles not known to a broader public. Only few publications over the last decades tried to present a more comprehensive overview of heir chemistry, chemical composition, their physical and analytical properties, their applications, and their sometimes astonishing history. Based on personal experience and expertise, the authors intend to present an overview on the main classes of waxes, their origin, history, future, and potential fate. Economical aspects like market size and development, ecological impacts and challenges, and regulatory issues are also addressed. Waxes are indispensable products in everyday life and in industry and technology, though mostly not even visible or distinguishable to experts. They deserve more than the role of a “poor cousin” in chemistry and technology.
This carefully prepared manuscript presents elimination theory in weighted projective spaces over arbitrary noetherian commutative base rings. Elimination theory is a classical topic in commutative algebra and algebraic geometry, and it has become of renewed importance recently in the context of applied and computational algebra. This monograph pro
Since the first edition that was published in 1998 we have seen manychanges in ophthalmology from advancements in laser surgery to new techniques in cataract surgery. With these new developing advancements symptoms, diagnosis, and treatments in ocular disease have also begun to change. Early diagnosis and management of ocular infection is essential
Psychocutaneous Medicine offers an overview of diseases in psychosomatic dermatology and creates a bridge between cutaneous and emotional disorders using extraordinary illustrations and clinical images of psychosomatic dermatology. It covers both common and rare diseases and helps doctors and psychologists recognize and deal with psychosocial features in dermatology and venerology. This superbly illustrated clinical atlas with concise text passages follows the American diagnosis classification DSM-V and current evidence-based guidelines. It allows rapid recognition of masked emotional disorders and thus administration of the most effective and efficient treatment as early as possible. Hone your diagnostic vision for psychosomatic disorders. Treat your patients efficiently and effectively. Psychocutaneous Medicine is a picture atlas and textbook that is indispensable for dermatologists, psychologists, pediatricians and general practitioners.
This comprehensive sourcebook combines evidence-based insights from more than 1,000 studies from cannabinoid and consciousness research to present a convincing case for the powerful healing effects of medical marijuana on over 100 chronic symptoms and diseases. Written by a former paramedic with a PhD in alternative healthcare, this in-depth reference shows that the subtle shifts in awareness commonly observed in cannabis-using patients vastly contribute to these compounds' therapeutic potential. The Cannabis Health Index is organized into condition-specific chapters, with eye-catching ratings of cannabis efficacy for each symptom, along with recommendations for use, and sidebars that suggest related mindfulness-based practices that enhance the body's own ability to heal. Organized alphabetically from aging to wound care, with sections on a variety of conditions including infections, cancer, cardiovascular health, eye diseases, inflammatory diseases, neurological diseases, and much more, the Index reveals that the huge body of scientific studies focused on cannabis is a tremendously under-utilized repository of knowledge. In synthesizing the findings of these studies, Blesching brings clarity to the process of making informed decisions about cannabis as a valid treatment. Informative, user-friendly, and practical, The Cannabis Health Index presents striking evidence that cannabis is remarkable safe and effective when used within the proper therapeutic window, especially compared with the risks of managing chronic symptoms with pharmaceuticals.
Viel zu oft konzentrieren sich Anleger auf die Unternehmen im deutschen Leitindex. Nicht erst seit dem Wirecard-Skandal bestätigt sich: Das kann ein fataler Fehler sein. Denn die Nebenwerte-Indizes MDAX, SDAX oder TecDAX sowie die internationalen Börsenplätze schlagen den DAX um Längen, wenn es um die Wertentwicklung geht. Wichtig ist aber nicht nur die richtige Wahl der Aktien, sondern auch der richtige Zeitpunkt des Kaufs und (Teil-)Verkaufs. In diesem Buch werden systematisch alle Grundsätze der Hoch-Tief-Mut-Strategie gut verständlich erklärt und mit Einblicken in das Erfolgsdepot von Beate und Uwe Sander kombiniert. Die Autoren zeigen, über welch enormes Potenzial Nebenwerte verfügen. Dabei geht es nicht nur um die Nebenwerte-Börsenbarometer. Chancenreich sind auch ausländische Aktien, Aktienfonds und die beliebten Aktienkörbe-ETFs. In Kurslisten und Auswahldepots finden Börsenneulinge und fortgeschrittene Anleger wichtige Informationen zu zukunftsfähigen Titeln. Vorsichtige ebenso wie erfolgsorientierte und risikofreudige Anleger erhalten Vorschläge für den Aufbau eines zukunftsfähigen Depots ab 5 000 Euro.
A comprehensive account of the statistical theory of exponential families of stochastic processes. The book reviews the progress in the field made over the last ten years or so by the authors - two of the leading experts in the field - and several other researchers. The theory is applied to a broad spectrum of examples, covering a large number of frequently applied stochastic process models with discrete as well as continuous time. To make the reading even easier for statisticians with only a basic background in the theory of stochastic process, the first part of the book is based on classical theory of stochastic processes only, while stochastic calculus is used later. Most of the concepts and tools from stochastic calculus needed when working with inference for stochastic processes are introduced and explained without proof in an appendix. This appendix can also be used independently as an introduction to stochastic calculus for statisticians. Numerous exercises are also included.
From reviews to the first edtion: "Bornscheuer and Kazlauskas have set out, and succeeded, in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and proteases) for organic chemists. This is quite simply the best book of its type and can be unreservedly recommended to organic chemists who have an interest in using hydrolytic enzymes in synthesis." (Nicholas J. Turner, University of Edinburgh) "The book is an indispensable source of information on the use of hydrolases in organic synthesis. The subject matter is very well set out, and the chapters are clearly written and presented from a critical viewpoint. Bornscheuer and Kazlauskas have succeeded admirably in describing the capabilities and limitations of the use of hydrolytic enzymes and in critically evaluating them. No library should be without the book." (Fritz Theil, WITEGA Angewandte Werkstoff-Forschung GmbH, Berlin) The second edition of this extremely successful and well-proven book presents recent developments in the use of hydrolases for organic synthesis, reflecting in particular the enormous progress made in enzyme discovery and optimization with a new chapter on "Protein Sources and Optimization of Biocatalyst Performance". The renowned authors survey the stereoselective reactions of hydrolases, especially lipases, esterases and proteases, giving researchers an overview of what has worked in the past so that they can judge how to solve their own synthetic problems. In total, the book contains over one thousand chemical structures, rounded off by some 1,800 invaluable references.
This book comprehensively describes the physiological changes and consequences that occur in humans during spaceflight. It specifically presents the adaptations of the cardiovascular and the respiratory system. Specific changes occurring after 10, 20 or more days in space are depicted. Furthermore, the book explains various effective countermeasures that are required upon return of the astronauts to Earth. The book is a must-have for all biomedical and clinical researchers in the field of cardiovascular biology and respiration, and a fascinating reading for all interested laymen, who wish to understand a bit more about spaceflight research and technology.
About one decade has elapsed since the introduction of the Euro: Has the Euro proved to be a stable currency? Doubts might be left. Large segments of the financial system seem to be coming apart at the seams, bailout plans have been approved. Is even a withdrawal from the European Unification going to be likely? This sounds popular, but this may be an undertaking with an uncertain ending. The contributions do not intend to give rash answers. A strengthening of the Euro is necessary, and should be preferred to its abolition. To make the Euro fit for the future is the order of the day.
This book provides a comprehensive up-to-date presentation of some of the classical areas of reliability, based on a more advanced probabilistic framework using the modern theory of stochastic processes. This framework allows analysts to formulate general failure models, establish formulae for computing various performance measures, as well as determine how to identify optimal replacement policies in complex situations. In this second edition of the book, two major topics have been added to the original version: copula models which are used to study the effect of structural dependencies on the system reliability; and maintenance optimization which highlights delay time models under safety constraints. Terje Aven is Professor of Reliability and Risk Analysis at University of Stavanger, Norway. Uwe Jensen is working as a Professor at the Institute of Applied Mathematics and Statistics of the University of Hohenheim in Stuttgart, Germany. Review of first edition: "This is an excellent book on mathematical, statistical and stochastic models in reliability. The authors have done an excellent job of unifying some of the stochastic models in reliability. The book is a good reference book but may not be suitable as a textbook for students in professional fields such as engineering. This book may be used for graduate level seminar courses for students who have had at least the first course in stochastic processes and some knowledge of reliability mathematics. It should be a good reference book for researchers in reliability mathematics." --Mathematical Reviews (2000)
A practical and fascinating book on a topic at the forefront of communications technology. Field-Programmable Gate Arrays (FPGAs) are on the verge of revolutionizing digital signal processing. Novel FPGA families are replacing ASICs and PDSPs for front-end digital signal processing algorithms at an accelerating rate. The efficient implementation of these algorithms is the main goal of this book. It starts with an overview of today's FPGA technology, devices, and tools for designing state-of-the-art DSP systems. Each of the book’s chapter contains exercises. The VERILOG source code and a glossary are given in the appendices.
Divided into two parts, the first four chapters of Comets and their Origin refer to comets and their formation in general, describing cometary missions, comet remote observations, astrochemistry, artificial comets, and the chirality phenomenon. The second part covers the cometary ROSETTA mission, its launch, journey, scientific objectives, and instrumentations, as well as the landing scenario on a cometary nucleus. Along the way, the author presents general questions concerning the origin of terrestrial water and the molecular beginnings of life on Earth, as well as how the instruments used on a space mission like ROSETTA can help answer them. The text concludes with a chapter on what scientists expect from the ROSETTA mission and how its data will influence our life on Earth. As a result, the author elucidates highly topical and fascinating knowledge to scientists and students of various scientific backgrounds, allowing them to work with ROSETTA's data.
Optical Properties of Metal Clusters deals with the electronic structure of metal clusters determined optically. Clusters - as state intermediate between molecules and the extended solid - are important in many areas, e.g. in air pollution, interstellar matter, clay minerals, photography, heterogeneous catalysis, quantum dots, and virus crystals. This book extends the approaches of optical molecular and solid-state methods to clusters, revealing how their optical properties evolve as a function of size. Cluster matter, i.e. extended systems of many clusters - the most frequently occuring form - is also treated. The combination of reviews of experimental techniques, lists of results and detailed descriptions of selected experiments will appeal to experts, newcomers and graduate students in this expanding field.
This second edition of a bestselling textbook offers an instructive and comprehensive overview of our current knowledge of biocatalysis and enzyme technology. The book now contains about 40% more printed content. Three chapters are completely new, while the others have been thoroughly updated, and a section with problems and solutions as well as new case studies have been added. Following an introduction to the history of enzyme applications, the text goes on to cover in depth enzyme mechanisms and kinetics, production, recovery, characterization and design by protein engineering. The authors treat a broad range of applications of soluble and immobilized biocatalysts, including wholecell systems, the use of non-aqueous reaction systems, applications in organic synthesis, bioreactor design and reaction engineering. Methods to estimate the sustainability, important internet resources and their evaluation, and legislation concerning the use of biocatalysts are also covered.
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