United Kingdom Environmental Mutagen Society. Sub-Committee on Guidelines for Mutagenicity Testing's Books

This rigorous and practical account of the interpretation of mutagenicity test data draws upon the expertise of toxicologists and statisticians. Chemicals, such as drugs, food additives and pesticides, all need careful screening to eliminate potentially mutagenic compounds.

Originally published in 1993, this volume describes supplementary tests used to assess risks of in vitro mutagenicity when basic safety tests were inconclusive.

Originally published in 1993, this volume describes a complementary selection of tests to those described in the companion volume Basic Mutagenicity Tests (Cambridge University Press, 1990). These supplementary tests were used to assess risks of in vitro mutagenicity in those instances where the basic tests were inconclusive. As such, these tests had an important role in the assessment of the safety of compounds, drugs and chemicals. These supplementary test and guidelines, originally drawn up by the United Kingdom Environmental Mutagen Society (UKEMS) were fully revised in this publication to take full account of different regulatory guidelines and scientific advances. This volume will be of value to anyone with aninterest in regulatory affairs, mutagenicity testing and the registration of chemical products in the UK and Europe.

Originally published in 1993, this volume describes supplementary tests used to assess risks of in vitro mutagenicity when basic safety tests were inconclusive.

This publication sets out information on transgenic mutagenicity assays and assesses the possible role of these assays in toxicology testing and mechanistic research. It includes an overview of in vivo genotoxicity testing and of the data produced by various assays, as well as discussing the use of the assays in research and evaluating the role and potential added value of transgenic mutation assays in toxicology and risk assessment.

Book's by United Kingdom Environmental Mutagen Society. Sub-Committee on Guidelines for Mutagenicity Testing

Statistical Evaluation of Mutagenicity Test Data

Statistical Evaluation of Mutagenicity Test Data

Supplementary Mutagenicity Tests

Supplementary Mutagenicity Tests

Supplementary Mutagenicity Tests

Supplementary Mutagenicity Tests

Supplementary Mutagenicity Tests

Supplementary Mutagenicity Tests

Statistical Evaluation of Mutagenicity Test Data

Statistical Evaluation of Mutagenicity Test Data

Transgenic Animal Mutagenicity Assays

Transgenic Animal Mutagenicity Assays

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