The book presents an innovative technology based on injection of a very weak current to trace the quantity of a drug carried immediately after the administration. The book makes the reader familiar with the technology, from the conception through the design of the instrument, up to the preliminary clinical applications. In the first chapter, the method of transdermal drug delivery and the use of impedance spectroscopy in the dermatological field are presented. The second chapter describes a screening measurement campaign aimed at proving the feasibility of the assessment method and identifying the bandwidth of interest. The prototyping, validation and characterization of an instrument to measure the amount of drug delivered (DUSM: Drug Under Skin Meter) are presented in chapter three. In the fourth chapter three experimental campaigns, based on the electrical analysis of the biological tissue behavior due to the drug delivery, are reported: (i) laboratory emulation on eggplants, (ii) ex-vivo tests on pig ears, and finally (iii) in-vivo tests on human volunteers. In the fifth chapter a behavioral model, based on Finite Elements and Partial Differential Equation, of an impedance-based measurement system for assessing the drug released under the skin, during transdermal delivering, is proposed. The last chapter is dedicated to present a campaign in order to prove the suitability for insulin therapy applications. This book is intended for biomedical engineers, biomedical engineering students, operators working in the field of biomedical instrumentation, biotechnologists, and technicians of transdermal vehiculation.
The book presents an innovative technology based on injection of a very weak current to trace the quantity of a drug carried immediately after the administration. The book makes the reader familiar with the technology, from the conception through the design of the instrument, up to the preliminary clinical applications. In the first chapter, the method of transdermal drug delivery and the use of impedance spectroscopy in the dermatological field are presented. The second chapter describes a screening measurement campaign aimed at proving the feasibility of the assessment method and identifying the bandwidth of interest. The prototyping, validation and characterization of an instrument to measure the amount of drug delivered (DUSM: Drug Under Skin Meter) are presented in chapter three. In the fourth chapter three experimental campaigns, based on the electrical analysis of the biological tissue behavior due to the drug delivery, are reported: (i) laboratory emulation on eggplants, (ii) ex-vivo tests on pig ears, and finally (iii) in-vivo tests on human volunteers. In the fifth chapter a behavioral model, based on Finite Elements and Partial Differential Equation, of an impedance-based measurement system for assessing the drug released under the skin, during transdermal delivering, is proposed. The last chapter is dedicated to present a campaign in order to prove the suitability for insulin therapy applications. This book is intended for biomedical engineers, biomedical engineering students, operators working in the field of biomedical instrumentation, biotechnologists, and technicians of transdermal vehiculation.
The two great men, who stand on opposite sides of the church door, discuss some of the controversial issues of the day. One is the prince of the Church, a respected scholar and one of the pre-eminent ecumenical churchmen of Europe; and the other the world famous author of The Name of the Rose, a scholar, philosopher and self-declared secularist.
The time: 2000 to 2005, the years of neoconservatism, terrorism, the twenty-four-hour news cycle, the ascension of Bush, Blair, and Berlusconi, and the invasions of Afghanistan and Iraq. Umberto Eco's response is a provocative, passionate, and witty series of essays--which originally appeared in the Italian newspapers La Repubblica and L'Espresso--that leaves no slogan unexamined, no innovation unexposed. What led us into this age of hot wars and media populism, and how was it sold to us as progress? Eco discusses such topics as racism, mythology, the European Union, rhetoric, the Middle East, technology, September 11, medieval Latin, television ads, globalization, Harry Potter, anti-Semitism, logic, the Tower of Babel, intelligent design, Italian street demonstrations, fundamentalism, The Da Vinci Code, and magic and magical thinking.The famous author and respected scholar shows his practical, engaged side: an intellectual involved in events both local and global, a man concerned about taste, politics, education, ethics, and where our troubled world is headed.
In this prescient essay collection, the acclaimed author of Foucault’s Pendulum examines the cultural trends and perils at the dawn of the 21st century. In the last decade of the 20th century, Umberto Eco saw an urgent need to embrace tolerance and multiculturalism in the face of our world’s ever-increasing interconnectivity. At a talk delivered during the first Gulf War, he points out the absurdity of armed conflict in a globalized economy where the flow of information is unstoppable and the enemy is always behind the lines. Elsewhere, he questions the influence of the news media and identifies its contribution to our collective disillusionment with politics. In a deeply personal essay, Eco recalls his boyhood experience of Italy’s liberation from fascism. He then analyzes the universal elements of fascism, including the “cult of tradition” and a “suspicion of intellectual life.” And finally, in an open letter to an Italian cardinal, Eco reflects on a question underlying all the reflections in the book: What does it mean to be moral or ethical when one doesn't believe in God? “At just 111 pages, Five Moral Pieces packs a philosophical wallop surprising in such a slender book. Or maybe not so surprising. Eco's prose here is beautiful.”—January Magazine
A “scintillating collection” of essays on Disneyland, medieval times, and much more, from the author of Foucault’s Pendulum (Los Angeles Times). Collected here are some of Umberto Eco’s finest popular essays, recording the incisive and surprisingly entertaining observations of his restless intellectual mind. As the author puts it in the preface to the second edition: “In these pages, I try to interpret and to help others interpret some ‘signs.’ These signs are not only words, or images; they can also be forms of social behavior, political acts, artificial landscapes.” From Disneyland to holography and wax museums, Eco explores America’s obsession with artificial reality, suggesting that the craft of forgery has in certain cases exceeded reality itself. He examines Western culture’s enduring fascination with the middle ages, proposing that our most pressing modern concerns began in that time. He delves into an array of topics, from sports to media to what he calls the crisis of reason. Throughout these travels—both physical and mental—Eco displays the same wit, learning, and lively intelligence that delighted readers of The Name of the Rose and Foucault’s Pendulum. Translated by William Weaver
Playful parodies by the author of The Name of the Rose and Foucault's Pendulum. Here, Eco pokes fun at the oversophisticated, overacademic, and overintellectual, and along the way makes penetrating comments about our modern mass culture and the elitist avant-garde in art in criticism.
It is the year 1327. Franciscans in an Italian abbey are suspected of heresy, but Brother William of Baskerville's investigation is suddenly overshadowed by seven bizarre deaths. Translated by William Weaver. A Helen and Kurt Wolff Book
This essay collection by the revered public intellectual displays his “profound erudition, lively wit, and passion for ideas of all shapes and sizes” (Booklist). In these fourteen essays, Umberto Eco examines many of the ideas that have inspired his provocative and illuminating fiction. From the title essay—a disquisition of the notion that every country needs an enemy—he takes readers on an exploration of lost islands, mythical realms, and the medieval world. His topics range from indignant reviews of James Joyce’s Ulysses by fascist journalists, to an examination of Saint Thomas Aquinas’s notions about the soul of an unborn child, to censorship, violence and WikiLeaks. Here are essays full of passion, curiosity, and probing intellect by one of the world’s most esteemed scholars and critically acclaimed, best-selling novelists. “True wit and wisdom coexist with fierce scholarship inside Umberto Eco, a writer who actually knows a thing or two about being truly human.” — Buffalo News
How we create and organize knowledge is the theme of this major achievement by Umberto Eco. Demonstrating once again his inimitable ability to bridge ancient, medieval, and modern modes of thought, he offers here a brilliant illustration of his longstanding argument that problems of interpretation can be solved only in historical context.
Pada tahun 1992, Colonna ditawari honor menggiurkan untuk menulis sebuah memoar. Subjeknya, Braggadocio, yakin bahwa mayat Mussolini adalah tubuh ganda dan bagian dari plot Fasis yang lebih luas. Ketika sebuah mayat ditemukan dalam kondisi mati ditikam di gang tersembunyi, Colonna tersentak. Dipicu oleh teori konspirasi, mafia, cinta, korupsi, dan pembunuhan, Nomor Nol bergema bersama bentrokan kekuatan yang telah membentuk Italia sejak Perang Dunia Kedua. * Bagi saya, dia (Eco) tetap menjadi model intelektual Eropa yang membuat ide-ide kompleks dapat diakses. Banyak dari kita memiliki harapan untuk mendamaikan tarikan magnetis karya fiksi dengan kebajikan yang lebih kaya makna dalam literatur besar: Eco adalah salah satu dari sedikit yang sanggup mewujudkannya. Jonathan Coe, The Guardian * Pengantar Nomor Nol adalah salah satu buku Umberto Eco, seorang filsuf, pakar abad pertengahan, ahli semiotika, kritikus budaya dan novelis asal Italia. Eco telah menulis tujuh novel dan merupakan anggota kehormatan American Academy of Arts and Letters.
This book is significant for its concept of "openness"--the artist's decision to leave arrangements of some constituents of a work to the public or to chance--and for its anticipation of two themes of literary theory: the element of multiplicity and plurality in art, and the insistence on literary response as an interaction between reader and text.
A literary prank leads to deadly danger in this “endlessly diverting” intellectual thriller by the author of The Name of the Rose (Time). Bored with their work, three Milanese book editors cook up an elaborate hoax that connects the medieval Knights Templar with occult groups across the centuries. Becoming obsessed with their own creation, they produce a map indicating the geographical point from which all the powers of the earth can be controlled—a point located in Paris, France, at Foucault’s Pendulum. But in a fateful turn the joke becomes all too real. When occult groups, including Satanists, get wind of the Plan, they go so far as to kill one of the editors in their quest to gain control of the earth. Orchestrating these and other diverse characters into his multilayered semiotic adventure, Umberto Eco has created a superb cerebral entertainment. "An intellectual adventure story…sensational, thrilling, and packed with arcana."—The Washington Post Book World
In Six Walks in the Fictional Woods Umberto Eco shares with us his Secret Life as a reader—his love for MAD magazine, for Scarlett O'Hara, for the nineteenth-century French novelist Nerval's Sylvie, for Little Red Riding Hood, Agatha Christie, Agent 007 and all his ladies. We see, hear, and feel Umberto Eco, the passionate reader who has gotten lost over and over again in the woods, loved it, and come back to tell the tale, The Tale of Tales. Eco tells us how fiction works, and he also tells us why we love fiction so much. This is no deconstructionist ripping the veil off the Wizard of Oz to reveal his paltry tricks, but the Wizard of Art himself inviting us to join him up at his level, the Sorcerer inviting us to become his apprentice.
How do we know a cat is a cat . . . and why do we call it a cat? An “intriguing and often fascinating” look at words, perceptions, and the relationship between them (Newark Star-Ledger). In Kant and the Platypus, the renowned semiotician, philosopher, and bestselling author of The Name of the Rose and Foucault’s Pendulum explores the question of how much of our perception of things is based on cognitive ability, and how much on linguistic resources. In six remarkable essays, Umberto Eco explores in depth questions of reality, perception, and experience. Basing his ideas on common sense, Eco shares a vast wealth of literary and historical knowledge, touching on issues that affect us every day. At once philosophical and amusing, Kant and the Platypus is a tour of the world of our senses, told by a master of knowing what is real and what is not. “An erudite, detailed inquirity into the philosophy of mind . . . Here, Eco is continental philosopher, semiotician, and cognitive scientist rolled all into one.” —Library Journal (starred review)
To recall his memories, Yambo withdraws to the family home where he searches old newspapers, comics, records, photo albums, and diaries to relive the story of his generation: Mussolini, Catholic education and guilt, Josephine Baker, Flash Gordon, and Fred Astaire.
“Impishly witty and ingeniously irreverent” essays on topics from cell phones to librarians, by the author of The Name of the Rose and Foucault’s Pendulum (The Atlantic Monthly). A cosmopolitan curmudgeon the Los Angeles Times called “the Andy Rooney of academia”—known for both nonfiction and novels that have become blockbuster New York Times bestsellers—Umberto Eco takes readers on “a delightful romp through the absurdities of modern life” (Publishers Weekly) as he journeys around the world and into his own wildly adventurous mind. From the mundane details of getting around on Amtrak or in the back of a cab, to reflections on computer jargon and soccer fans, to more important issues like the effects of mass media and consumer civilization—not to mention the challenges of trying to refrigerate an expensive piece of fish at an English hotel—this renowned writer, semiotician, and philosopher provides “an uncanny combination of the profound and the profane” (San Francisco Chronicle). “Eco entertains with his clever reflections and with his unique persona.” —Kirkus Reviews Translated from the Italian by William Weaver
Umberto Eco published his first novel, The Name of the Rose, in 1980, when he was nearly fifty. In these “confessions,” the author, now in his late seventies, looks back on his long career as a theorist and his more recent work as a novelist, and explores their fruitful conjunction. He begins by exploring the boundary between fiction and nonfiction—playfully, seriously, brilliantly roaming across this frontier. Good nonfiction, he believes, is crafted like a whodunnit, and a skilled novelist builds precisely detailed worlds through observation and research. Taking us on a tour of his own creative method, Eco recalls how he designed his fictional realms. He began with specific images, made choices of period, location, and voice, composed stories that would appeal to both sophisticated and popular readers. The blending of the real and the fictive extends to the inhabitants of such invented worlds. Why are we moved to tears by a character’s plight? In what sense do Anna Karenina, Gregor Samsa, and Leopold Bloom “exist”? At once a medievalist, philosopher, and scholar of modern literature, Eco astonishes above all when he considers the pleasures of enumeration. He shows that the humble list, the potentially endless series, enables us to glimpse the infinite and approach the ineffable. This “young novelist” is a master who has wise things to impart about the art of fiction and the power of words.
The Prague Cemetery is the #1 international bestselling historical novel from the award-winning and New York Times bestselling author of The Name of the Rose, Umberto Eco. Nineteenth-century Europe—from Turin to Prague to Paris—abounds with the ghastly and the mysterious. Jesuits plot against Freemasons. Italian republicans strangle priests with their own intestines. French criminals plan bombings by day and celebrate Black Masses at night. Every nation has its own secret service, perpetrating forgeries, plots, and massacres. Conspiracies rule history. From the unification of Italy to the Paris Commune to the Dreyfus Affair to The Protocols of the Elders of Zion, Europe is in tumult and everyone needs a scapegoat. But what if behind all of these conspiracies, both real and imagined, lay one lone man? “Choreographed by a truth that is itself so strange a novelist need hardly expand on it to produce a wondrous tale... Eco is to be applauded for bringing this stranger-than-fiction truth vividly to life.” —The New York Times
A posthumous collection of essays by one of our greatest contemporary thinkers that provides a towering vision of Western culture. In Umberto Eco’s first novel, The Name of the Rose, Nicholas of Morimondo laments, “We no longer have the learning of the ancients, the age of giants is past!” To which the protagonist, William of Baskerville, replies: “We are dwarfs, but dwarfs who stand on the shoulders of those giants, and small though we are, we sometimes manage to see farther on the horizon than they.” On the Shoulders of Giants is a collection of essays based on lectures Eco famously delivered at the Milanesiana Festival in Milan over the last fifteen years of his life. Previously unpublished, the essays explore themes he returned to again and again in his writing: the roots of Western culture and the origin of language, the nature of beauty and ugliness, the potency of conspiracies, the lure of mysteries, and the imperfections of art. Eco examines the dynamics of creativity and considers how every act of innovation occurs in conversation with a superior ancestor. In these playful, witty, and breathtakingly erudite essays, we encounter an intellectual who reads comic strips, reflects on Heraclitus, Dante, and Rimbaud, listens to Carla Bruni, and watches Casablanca while thinking about Proust. On the Shoulders of Giants reveals both the humor and the colossal knowledge of a contemporary giant.
The year is 1643. Roberto, a young nobleman, survives war, the Bastille, exile and shipwreck as he voyages to a Pacific island straddling the date meridian. There he waits now, alone on the mysteriously deserted Daphne, separated by treacherous reefs from the island beyond: the island of the day before. If he could reach it, time - and his misfortunes - might be reversed. But first he must learn to swim...
It is impossible to think about the present or the future of universities without taking into account the fact that universities live in a world dominated by mass media." - U Eco. Eco wrote this short essay when he was awarded an Honorary Doctorate in letters by Laurentian University (Canada). The essay appears in English, French, and Italian.
One is a cardinal, and a respected New Testament scholar; the other is the world-famous author of The Name of the Rose, a scholar, philosopher, and self-declared secularist.In this intellectually stimulating dialogue, often adversarial but always amicable, these two great men, who stand on opposite sides of the church door, discuss the controversies of our day, including: ethics, women in the church, abortion and the apocalypse.
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