During the past decade there has been an explosion in computation and information technology. With it have come vast amounts of data in a variety of fields such as medicine, biology, finance, and marketing. The challenge of understanding these data has led to the development of new tools in the field of statistics, and spawned new areas such as data mining, machine learning, and bioinformatics. Many of these tools have common underpinnings but are often expressed with different terminology. This book describes the important ideas in these areas in a common conceptual framework. While the approach is statistical, the emphasis is on concepts rather than mathematics. Many examples are given, with a liberal use of color graphics. It should be a valuable resource for statisticians and anyone interested in data mining in science or industry. The book’s coverage is broad, from supervised learning (prediction) to unsupervised learning. The many topics include neural networks, support vector machines, classification trees and boosting---the first comprehensive treatment of this topic in any book. This major new edition features many topics not covered in the original, including graphical models, random forests, ensemble methods, least angle regression & path algorithms for the lasso, non-negative matrix factorization, and spectral clustering. There is also a chapter on methods for “wide” data (p bigger than n), including multiple testing and false discovery rates. Trevor Hastie, Robert Tibshirani, and Jerome Friedman are professors of statistics at Stanford University. They are prominent researchers in this area: Hastie and Tibshirani developed generalized additive models and wrote a popular book of that title. Hastie co-developed much of the statistical modeling software and environment in R/S-PLUS and invented principal curves and surfaces. Tibshirani proposed the lasso and is co-author of the very successful An Introduction to the Bootstrap. Friedman is the co-inventor of many data-mining tools including CART, MARS, projection pursuit and gradient boosting.
Each chapter begins with a discussion of its composer's song-output and of the poets and poetry he sets, and goes on to give an account of the influences on him and the hallmarks of his style; the songs are then discussed in detail, focusing on the major works. The text is illustrated with musical examples and there is a comprehensive bibliography and index"--Jacket.
The Trouble with Higher Education is a powerful and topical critique of the Higher Education system in the UK, with relevance to countries with similar systems. Based on the authors’ experiences that span over 30+ years of fieldwork, the issues discussed focus on the problems facing the principle responsibilities of universities: teaching, learning and research. The first half of the book identifies a number of problems that have followed the growth of mass education. It examines their causes and explains their damaging effects. The second half of the book offers a broad vision and makes a number of practical suggestions for ameliorating the problems and improving higher education. Supported by research, the suggestions include: ways of managing universities; proper inspection; better ways of organising students’ learning; improving teaching and learning; better approaches to assessment, and the proper use of ideas such as learning outcomes. Topics discussed include: Chronic under-funding, the replacement of student grants with loans and the introduction of tuition fees. The growth of managerialism. The emphasis on accountability and decline of trust. The growth of a competitive, market ethos. Modular degrees, knowledge treated as a commodity and students seen as customers. The drift towards a two-tiered system, with teaching colleges and research universities. Casualisation of the academic profession. The Trouble with Higher Education is aimed primarily at a professional audience of academics, educationalists, managers, administrators and policy makers, but would interest anyone concerned about higher education. It is suited to professional development courses, and Master’s and doctoral level studies.
Unraveling Environmental Disasters, Second Edition provides scientific explanations of the most threatening current and future environmental disasters, including an analysis of ways disasters could have been prevented and how to minimize risk of similar disasters in the future. In this new edition the authors provide foundational knowledge on why certain environmental disasters occur and ways of reducing the risk of recurrences. Anyone involved in teaching or working in the main sciences of physics, chemistry, and biology, or in the applied sciences, including engineering, design, planning, and homeland security, should read the book to become acquainted with these very important issues. - Evaluates natural hazards and disasters with an emphasis on lessons learned for better future forecasting - Considers the impact of human systems on environmental disasters, treating disasters as complex systems - Provides detailed predictions, based upon sound science, on why disasters occur - Includes fully updated chapters on food, health, and water - Focuses on both theoretical and practical aspects of each disaster - Includes disasters related to climate change and pollution
As a volume in the series CNS Neurotransmitters and Neuromodulators, this text is destined to become a definitive reference. Well-known international authors have contributed up-to-date reviews covering a wide-range of interdisciplinary aspects of neuroactive steroid function. Specifically, this volume includes chapters dealing with the expression and properties of steroid receptors in the central nervous system (CNS); steroid interactions with amino acids, amines, and growth factors; electrophysiology; hypothalamic and feeding control; and the extremely topical issue of steroid influences on sexual differentiation of the brain. Neuroactive Steroids is an indispensable reference work for any researcher involved with steroids in the CNS, particularly in the areas of physiology, anatomy, neuropharmacology, neurochemistry, psychiatry, and molecular biology. In addition, it provides the perfect one-stop introduction for students.
Bringing Bayesian Models to Life empowers the reader to extend, enhance, and implement statistical models for ecological and environmental data analysis. We open the black box and show the reader how to connect modern statistical models to computer algorithms. These algorithms allow the user to fit models that answer their scientific questions without needing to rely on automated Bayesian software. We show how to handcraft statistical models that are useful in ecological and environmental science including: linear and generalized linear models, spatial and time series models, occupancy and capture-recapture models, animal movement models, spatio-temporal models, and integrated population-models. Features: R code implementing algorithms to fit Bayesian models using real and simulated data examples. A comprehensive review of statistical models commonly used in ecological and environmental science. Overview of Bayesian computational methods such as importance sampling, MCMC, and HMC. Derivations of the necessary components to construct statistical algorithms from scratch. Bringing Bayesian Models to Life contains a comprehensive treatment of models and associated algorithms for fitting the models to data. We provide detailed and annotated R code in each chapter and apply it to fit each model we present to either real or simulated data for instructional purposes. Our code shows how to create every result and figure in the book so that readers can use and modify it for their own analyses. We provide all code and data in an organized set of directories available at the authors' websites.
Further and Higher Education in the UK has expanded greatly in recent years, bringing into education large numbers of young people who present teachers with new challenges. At the same time, there is an immense pressure to improve the quality of learning and teaching, and to encourage students to be active participants in the process. This book is aimed at teachers, aspiring teachers and other professionals in upper secondary schools, further education colleges and universities who wish to increase learner motivation and to create opportunities for greater learner autonomy. It will: * relate learning theory to practice * provide practical help for teachers to understand how they tend to interact with students * suggest how they may build a repertoire of teaching styles that foster sharing of responsibility with learners for more effective learning.
Cancer is a dreaded disease. One in two people will be diagnosed with cancer within their lifetime. Medical Statistics for Cancer Studies shows how cancer data can be analysed in a variety of ways, covering cancer clinical trial data, epidemiological data, biological data, and genetic data. It gives some background in cancer biology and genetics, followed by detailed overviews of survival analysis, clinical trials, regression analysis, epidemiology, meta-analysis, biomarkers, and cancer informatics. It includes lots of examples using real data from the author’s many years of experience working in a cancer clinical trials unit. Features: A broad and accessible overview of statistical methods in cancer research Necessary background in cancer biology and genetics Details of statistical methodology with minimal algebra Many examples using real data from cancer clinical trials Appendix giving statistics revision.
The twenty-first century has seen a breathtaking expansion of statistical methodology, both in scope and in influence. 'Big data', 'data science', and 'machine learning' have become familiar terms in the news, as statistical methods are brought to bear upon the enormous data sets of modern science and commerce. How did we get here? And where are we going? This book takes us on an exhilarating journey through the revolution in data analysis following the introduction of electronic computation in the 1950s. Beginning with classical inferential theories - Bayesian, frequentist, Fisherian - individual chapters take up a series of influential topics: survival analysis, logistic regression, empirical Bayes, the jackknife and bootstrap, random forests, neural networks, Markov chain Monte Carlo, inference after model selection, and dozens more. The distinctly modern approach integrates methodology and algorithms with statistical inference. The book ends with speculation on the future direction of statistics and data science.
The thermodynamic properties of seawater have recently been redefined as the International Thermodynamic Equation of Seawater—2010 (TEOS-10 for short), and here we summarize the changes to oceanographic practices that are needed to take advantage of this new international standard. A key feature of TEOS-10 is that the thermodynamic quantities are functions of a new salinity variable, Absolute Salinity, which incorporates the effects of spatial differences in seawater composition. TEOS-10 also treats the “heat content” of seawater in a more consistent and natural fashion through the introduction of a new temperature variable, Conservative Temperature, which replaces potential temperature. Since TEOS-10 includes fundamental equations of state also for ice and for humid air, thermodynamically consistent and complete relationships now exist between all the thermodynamic properties of fresh water, seawater, ice and humid air.
This thorough revision and update of the popular second edition contains everything the student needs to know about the psychology of language: how we understand, produce, and store language.
Within a practical business context of the changing, competitive climate, this book details the implications for marketing strategy. New chapters cover topics such as credit cards and customer care, while several relevant case studies have also been added. Combining analysis of principles, concepts and techniques with sound practical advice, 'Marketing Financial Services' is ideal for students on degree and postgraduate courses, including Chartered Institute of Bankers. There is also a tutor resource pack to accompany the case studies in this textbook.
On Christmas Eve 1876, Portsmouth citizens watched flames reduce their largest meetinghouse and entertainment hall to ashes. During the following year, local families, businessmen, and craftsmen combined their resources to build a new auditorium with state-of-the-art lighting, rigging, staging, and seating-a comfortable venue for public addresses, charity functions, and international entertainment. The Music Hall, Portsmouth, was born. Twain spoke from her stage, Sousa's brass echoed from her walls, and Edison's films brought her silver screen to life. Enduring war, depression, and multiple threats of destruction, this grand hall today stands as New Hampshire's oldest operating theater. Showcasing the world's finest stage and screen talent, offering artistic education to young and old, and hosting fundraisers and private events, the Music Hall is a testament to the necessity of arts in local culture and the strength of a community's resolve.
Japanese companies operating internationally resemble Western multinationals only superficially. They are 'reluctant' because outward economic dependency compels them to venture overseas - into environments where they cannot enjoy the same high degree of control and support that they do in Japan. There is no generally accepted view of Japanese management among writers in Europe and America and yet effective management has been a major factor in the advance of Japanese companies. The different approaches to Japanese management and its basic concepts are discussed here, together with the problems of multinationalization. First published in 1983, this title is part of the Bloomsbury Academic Collections series.
GRITTY, NEWCASTLE-SET CRIME FOR FANS OF IAN RANKIN AND ROBERT GALBRAITH. WINNER OF THE CWA JOHN CREASEY DAGGER AND OF THE SPECSAVERS DEBUT CRIME NOVEL AWARD. A THEAKSTON'S NEW BLOOD AUTHOR FOR 2020 AND SHORTLISTED FOR THE THEAKSTON'S OLD PECULIER CRIME NOVEL OF THE YEAR AWARD. 'Fresh, original, authentic and gritty - should be an instant classic' LEE CHILD 'Intricate, expertly paced with a shocking conclusion ... Jimmy is a character you root for from page one ... Simply supberb' M. W. CRAVEN, author of THE PUPPET SHOW It started with a splash. Jimmy, a homeless veteran grappling with PTSD, did his best to pretend he hadn't heard it - the sound of something heavy falling into the Tyne at the height of an argument between two men on the riverbank. Not his fight. Then he sees the headline: GIRL IN MISSING DAD PLEA. The girl, Carrie, reminds him of someone he lost, and this makes his mind up: it's time to stop hiding from his past. But telling Carrie, what he heard - or thought he heard - turns out to be just the beginning of the story. The police don't believe him, but Carrie is adamant that something awful has happened to her dad and Jimmy agrees to help her, putting himself at risk from enemies old and new. But Jimmy has one big advantage: when you've got nothing, you've got nothing to lose. Available to pre-order now: The Silent Killer, first in a brand-new series of thrillers due in July
Three Score Years and Ten: Or More? delves into the enduring fascination with individuals who live beyond 100 years. The intrigue centres not only on the accomplishment itself but also on the mysteries of how and why these people achieve such remarkable longevity. This research shifts its focus from contemporary centenarians, whose ages can be more reliably verified due to improved record-keeping, to an earlier era marked by less clear historical records. It investigates the genesis of this interest and the emergence of what could be termed a ‘cult of centenarianism.’ During this period, claims of extreme old age sparked debates between believers and sceptics, creating a cultural divide. The book also examines the significant role media played in this phenomenon. The portrayal and promotion of centenarians by the media of the time laid the groundwork for themes explored in this book, contributing to the ongoing public intrigue surrounding individuals of advanced age.
In this revised and updated edition particular attention has been paid to the practical implementations of digital filters, covering such topics as microprocessors-based filters, single-chip DSP devices, computer processing of 2-dimensional signals and VLSI signal processing.
Chemistry explores the way atoms interact, the constitution of the stars, and the human genome. Knowledge of chemistry makes it possible for us to manufacture dyes and antibiotics, metallic alloys, and other materials that contribute to the necessities and luxuries of human life. In Transforming Matter, noted historian Trevor H. Levere emphasizes that understanding the history of these developments helps us to appreciate the achievements of generations of chemists. Levere examines the dynamic rise of chemistry from the study of alchemy in the seventeenth century to the development of organic and inorganic chemistry in the age of government-funded research and corporate giants. In the past two centuries, he points out, the number of known elements has quadrupled. And because of synthesis, chemistry has increasingly become a science that creates much of what it studies. Throughout the book, Levere follows a number of recurring themes: theories about the elements, the need for classification, the status of chemical science, and the relationship between practice and theory. He illustrates these themes by concentrating on some of chemistry's most influential and innovative practitioners. Transforming Matter provides an accessible and clearly written introduction to the history of chemistry, telling the story of how the discipline has developed over the years.
Ideal for microbiology/science majors The third edition of Microbiology provides in-depth coverage of the science of microscopic organisms. Providing a balanced presentation of foundational concepts, real-world applications, and current research and experimentation, this comprehensive textbook facilitates a thorough understanding of the scope, nature, and complexity of microbiology. The text approaches the subject within the context of exploration and experimentation, integrating a wealth of classroom-tested pedagogical features. The material is organized around the three pillars of physiology, ecology and genetics — helping students appreciate the interconnected and dynamic nature of microbiology as they explore individual microbes and the relation between different types of microbes, other organisms, and the environment. Detailed yet accessible chapters illustrate how an experiment proceeds, explain how microbes replicate, clarify the flow of concept processes, and summarize key points. Challenging end-of-chapter questions both test students' understanding of the material and strengthen critical thinking skills. This new edition contains up-to-date coverage of topics including DNA replication and gene expression, viral pathogenesis, microbial biotechnology, adaptive immunity, the control of infectious diseases, the microbiology of food and water, and integrated coverage of COVID-19.
Medicine and medical research continue to grow rapidly in complexity alongside the changes in healthcare policy, discoveries, and the regulation and economics of the same. In the midst of these sea changes, patients and their families navigate (or negotiate) the reshaped landscape called the academic medical center or the teaching hospital. These changes create confusion and anxiety for patients and families in crises as the prospects of illness, death, and loss compete against and strain their coping abilities. A man they call Jacks helps patients and families navigate the maze. Jacks serves as a chaplain, and these are some of the stories he lives with the people God places in his care. As one who journeys alongside patients and their loved ones, Jacks embraces and struggles with the questions felt by so many but openly discussed by so few. He authentically strains to understand the circumstances in which people find themselves, without judgment, while controlling his own emotions to the things he witnesses. Jacks does not pretend to have the answers. Jacks understands one thing: compassion can bridge the divides created by crisis.
This is a story about Suzanna Bailey, who at the age of fourteen months began experiencing epileptic seizures. Consequently, these seizures led to countless appointments with medical professionals. Six successive brain surgeries left her with life-changing brain injuries, resulting in physical disabilities and behavioural challenges.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.