Heir to a conservative political dynasty, Shinzo Abe entered politics burdened by high expectations: that, in ruling Japan, he would change it fundamentally. In 2007, seemingly overwhelmed, he resigned only a year after becoming Japan's youngest postwar prime minister. Yet, after five years ofreflection and reinvention, he masterfully regained the premiership in 2012, and now dominates Japanese democracy as no leader has done before.Abe has inspired fierce loyalty among his followers. He has cowed Japan's left by pursuing an ambitious program of reflating the economy and strengthening the armed forces and national security establishment. And, on the international stage, he has staked a leadership role for Japan in Asia, aregion being rapidly transformed by the rise of China and India. Abe's stature has only grown in the age of 'America First': he has both taken steps to preserve an ironclad relationship with the mercurial US president, and has himself become an undisputed leader of the besieged world order.In The Iconoclast, veteran Japan-watcher Tobias Harris tells the story of Abe's meteoric rise and stunning fall, his remarkable comeback, and his unlikely emergence as a global statesman struggling to lay the groundwork for Japan's survival in a turbulent century.
Heir to a conservative political dynasty, Shinzo Abe entered politics burdened by high expectations: that, in ruling Japan, he would change it fundamentally. In 2007, seemingly overwhelmed, he resigned only a year after becoming Japan's youngest postwar prime minister. Yet, after five years ofreflection and reinvention, he masterfully regained the premiership in 2012, and now dominates Japanese democracy as no leader has done before.Abe has inspired fierce loyalty among his followers. He has cowed Japan's left by pursuing an ambitious program of reflating the economy and strengthening the armed forces and national security establishment. And, on the international stage, he has staked a leadership role for Japan in Asia, aregion being rapidly transformed by the rise of China and India. Abe's stature has only grown in the age of 'America First': he has both taken steps to preserve an ironclad relationship with the mercurial US president, and has himself become an undisputed leader of the besieged world order.In The Iconoclast, veteran Japan-watcher Tobias Harris tells the story of Abe's meteoric rise and stunning fall, his remarkable comeback, and his unlikely emergence as a global statesman struggling to lay the groundwork for Japan's survival in a turbulent century.
A new account of the central role developmental processes play in evolution A new scientific view of evolution is emerging—one that challenges and expands our understanding of how evolution works. Recent research demonstrates that organisms differ greatly in how effective they are at evolving. Whether and how each organism adapts and diversifies depends critically on the mechanistic details of how that organism operates—its development, physiology, and behavior. That is because the evolutionary process itself has evolved over time, and continues to evolve. The scientific understanding of evolution is evolving too, with groundbreaking new ways of explaining evolutionary change. In this book, a group of leading biologists draw on the latest findings in evolutionary genetics and evo-devo, as well as novel insights from studies of epigenetics, symbiosis, and inheritance, to examine the central role that developmental processes play in evolution. Written in an accessible style, and illustrated with fascinating examples of natural history, the book presents recent scientific discoveries that expand evolutionary biology beyond the classical view of gene transmission guided by natural selection. Without undermining the central importance of natural selection and other Darwinian foundations, new developmental insights indicate that all organisms possess their own characteristic sets of evolutionary mechanisms. The authors argue that a consideration of developmental phenomena is needed for evolutionary biologists to generate better explanations for adaptation and biodiversity. This book provides a new vision of adaptive evolution.
Reviews our current understanding of the role of protein oxidation in aging and age-related diseases Protein oxidation is at the core of the aging process. Setting forth a variety of new methods and approaches, this book helps researchers conveniently by exploring the aging process and developing more effective therapies to prevent or treat age-related diseases. There have been many studies dedicated to the relationship between protein oxidation and age-related pathology; now it is possible for researchers and readers to learn new techniques as utilizing protein oxidation products as biomarkers for aging. Protein Oxidation and Aging begins with a description of the tremendous variety of protein oxidation products. Furthermore, it covers: Major aspects of the protein oxidation process Cellular mechanisms for managing oxidized proteins Role of protein oxidation in aging Influence of genetic and environmental factors on protein oxidation Measuring protein oxidation in the aging process Protein oxidation in age-related diseases References at the end of each chapter serve as a gateway to the growing body of original research studies and reviews in the field.
Now in its sixth edition, this highly-regarded book is designed as an introductory text on the principles of diagnosis, staging and treatment of tumours. The new edition: Includes up-to-date information on the most recent techniques and therapies available Emphasises the importance of multidisciplinary teamwork in the care of cancer patients Highlights frequent dilemmas and difficulties encountered during cancer management Features the important contributions of a new author Professor Daniel Hochhauser Contains a brand-new two-colour design As with previous editions, the first part of the book is devoted to the mechanisms of tumour development and cancer treatment. This is followed by a systematic account of the current management of individual major cancers. For each tumour there are details of the pathology, mode of spread, clinical presentation, staging and treatment with radiotherapy and chemotherapy. This accessible and practical resource will be invaluable to trainees in oncology, palliative care and general medicine, as well as specialist nurses, general practitioners, medical students, and professions allied to medicine. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play or the MedHand Store.
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