Tjitske Heida's Books

The Subthalamic Nucleus

Part I: Development, Cytology, Topography and Connections

By: Enrico Marani,Tjitske Heida,Egbert A. J. F. Lakke,Kamen G. Usunoff

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The Subthalamic Nucleus

Part I: Development, Cytology, Topography and Connections

By: Enrico Marani,Tjitske Heida,Egbert A. J. F. Lakke,Kamen G. Usunoff

This monograph on the subthalamic nucleus accentuates the gap between experimental animal and human information concerning subthalamic development, cytology, topography and connections.

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Page Count

130

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3540794603

ISBN 13

9783540794608

Electric Field-Induced Effects on Neuronal Cell Biology Accompanying Dielectrophoretic Trapping

By: Tjitske Heida

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Electric Field-Induced Effects on Neuronal Cell Biology Accompanying Dielectrophoretic Trapping

By: Tjitske Heida

The concept of the cultured neuron probe was induced by the possible selective stimulation of nerves for functional recovery after a neural lesion or disease. The probe consists of a micro-electrode array on top of which groups of neuronal cells are cultured. An efficient method to position groups of neuronal cells on top of the stimulation sites of the micro-electrode array is developed. With negative dielectrophoretic forces, produced by non-uniform electric fields on polarizable particles, neuronal cells are trapped. Experimental results and model simulations describe the trapping process and its effect on neuronal cell viability.

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128

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3642554695

ISBN 13

9783642554698

The Subthalamic Nucleus

Part II: Modelling and Simulation of Activity

By: Tjitske Heida,Enrico Marani,Kamen G. Usunoff

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The Subthalamic Nucleus

Part II: Modelling and Simulation of Activity

By: Tjitske Heida,Enrico Marani,Kamen G. Usunoff

Part II starts with a systemic model of the basal ganglia to evaluate the position of the STN in the direct, indirect and hyperdirect pathways. A summary of in vitro studies is given, describing STN spontaneous activity as well as responses to depolarizing and hyperpolarizing inputs, and high frequency stimulation. STN bursting activity and the underlying ionic mechanisms are investigated. Deep brain stimulation used for symptomatic treatment of Parkinson’s disease is discussed in terms of the elements that are influenced and its hypothesized mechanisms. This part of the monograph pays attention to the pedunculopontine-subthalamic connections and tries in cell cultures to mimic neurotransmitter actions of the pedunculopontine nucleus and high frequency stimulation on cultured dissociated rat subthalamic neurons. STN cell models: single and multi compartment, and system level models are discussed in relation to subthalamic function and dysfunction. Part I and II are mutually compared.

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Page Count

101

Publisher

Springer Science & Business Media

Published Date

ISBN 10

354079462X

ISBN 13

9783540794622

The Subthalamic Nucleus

Part I: Development, Cytology, Topography and Connections

By: Enrico Marani,Tjitske Heida,Egbert A. J. F. Lakke,Kamen G. Usunoff

Write a review Read reviews Take a Quiz Solve Book Puzzle

The Subthalamic Nucleus

Part I: Development, Cytology, Topography and Connections

By: Enrico Marani,Tjitske Heida,Egbert A. J. F. Lakke,Kamen G. Usunoff

This monograph on the subthalamic nucleus accentuates the gap between experimental animal and human information concerning subthalamic development, cytology, topography and connections.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

130

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3540794603

ISBN 13

9783540794608

The Subthalamic Nucleus

Part II: Modelling and Simulation of Activity

By: Tjitske Heida,Enrico Marani,Kamen G. Usunoff

Write a review Read reviews Take a Quiz Solve Book Puzzle

The Subthalamic Nucleus

Part II: Modelling and Simulation of Activity

By: Tjitske Heida,Enrico Marani,Kamen G. Usunoff

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

101

Publisher

Springer Science & Business Media

Published Date

ISBN 10

354079462X

ISBN 13

9783540794622

Book's by Tjitske Heida

The Subthalamic Nucleus

The Subthalamic Nucleus

Electric Field-Induced Effects on Neuronal Cell Biology Accompanying Dielectrophoretic Trapping

Electric Field-Induced Effects on Neuronal Cell Biology Accompanying Dielectrophoretic Trapping

The Subthalamic Nucleus

The Subthalamic Nucleus

The Subthalamic Nucleus

The Subthalamic Nucleus

The Subthalamic Nucleus

The Subthalamic Nucleus

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