Mechanical cardiovascular assist devices must be properly designed to avoid damage to the blood they contact. The factors that affect the hemocompatibility of a cardiovascular assist device include three major non-physiological components – the material, fluid flow paths, and flow related stresses, - as well as the device interaction with the native vasculature. Furthermore, the interaction of the device with the blood is not static. Foreign surfaces activate blood components including platelets, leukocytes and the coagulation cascade. Thrombus formation on the surface of the device can alter the fluid dynamics in a manner that causes erythrocyte damage ranging from significant hemolysis to sub-lethal trauma that can take many days to weeks to develop into a significant clinical problem. This sub-lethal blood trauma is not easily detectable without special equipment, which is typically unavailable in routine clinical practice. Surveillance for blood damage is often sub-optimal in the clinical setting, but once clinically relevant hemolysis occurs, crucial decisions - device removal, replacement, or additional medical therapies including surgery or plasmapheresis - that take into account the risk/benefit of intervention must be quickly evaluated. The various preclinical designs and testing, surgical considerations, available surveillance techniques, and clinical consequences will be discussed using recent and historical case reports to highlight key points.
The Star Wars novels have been expanding the universe of this popular epic for decades. Now ten thrilling, action-packed classics have been collected in one convenient eBook bundle, a perfect introduction to the vibrant and varied eras of Star Wars history, past and future. With a rich cast of characters that includes beloved favorites—Luke Skywalker, Han Solo, and Princess Leia Organa—along with new villains and heroes, including the next generation of Jedi, these adventures will take fans for a breathtaking ride across time and space in the galaxy far, far away! The novels include: THE OLD REPUBLIC: DECEIVED by Paul S. Kemp REPUBLIC COMMANDO: HARD CONTACT by Karen Traviss DARK LORD: THE RISE OF DARTH VADER by James Luceno DEATH TROOPERS by Joe Schreiber LUKE SKYWALKER AND THE SHADOWS OF MINDOR by Matthew Stover X-WING: ROGUE SQUADRON by Michael A. Stackpole HEIR TO THE EMPIRE by Timothy Zahn NEW JEDI ORDER: VECTOR PRIME by R. A. Salvatore LEGACY OF THE FORCE: BETRAYAL by Aaron Allston CROSSCURRENT by Paul S. Kemp
Prepared by an international team of eminent atmospheric scientists, Mechanisms of Atmospheric Oxidation of the Oxygenates is an authoritative source of information on the role of oxygenates in the chemistry of the atmosphere. The oxygenates, including the many different alcohols, ethers, aldehydes, ketones, acids, esters, and nitrogen-atom containing oxygenates, are of special interest today due to their increased use as alternative fuels and fuel additives. This book describes the physical properties of oxygenates, as well as the chemical and photochemical parameters that determine their reaction pathways in the atmosphere. Quantitative descriptions of the pathways of the oxygenates from release or formation in the atmosphere to final products are provided, as is a comprehensive review and evaluation of the extensive kinetic literature on the atmospheric chemistry of the different oxygenates and their many halogen-atom substituted analogues. This book will be of interest to modelers of atmospheric chemistry, environmental scientists and engineers, and air quality planning agencies as a useful input for development of realistic modules designed to simulate the atmospheric chemistry of the oxygenates, their major oxidation products, and their influence on ozone and other trace gases within the troposhere.
Conan the Barbarian is one of the most recognisable characters of the past century. Created by Robert E. Howard and originating in the pages of pulp magazines of the 1930s, the sword and sorcery hero has been adapted for several films, TV programs, videogames and, of course, comic books! The stories in CONAN OMNIBUS 2: CITY OF THEIVES stay true to Howard's originals, and offer mountains of swashbuckling fun. Strap in and enjoy Conan's earliest adventures, created by comics greats Kurt Busiek and Cary Nord!
Clinical & Experimental Toxicology of Organophosphates and Carbamates considers the histochemical localization of cholinesterase in anticholinesterase poisoning. This book is organized into eight parts encompassing 59 chapters that discuss the pharmacology and toxicology of carbamates, as well as the neurobehavioral toxicology of anticholinesterases. Some of the topics covered in the book are the overview of biological and clinical aspects of organophosphates and carbamates; biochemical determination of cholinesterase activity in fluids and tissues; intermediate syndrome in anticholinesterase neurotoxicity; structure-activity relationships and anticholinesterase activity; and the molecular events in delayed neuropathy. Other parts deal with the cardiac effects of anticholinesterase agents and the ecotoxicological consequences of interactions between avian esterases and organophosphorus compounds. These topics are followed by discussions on the analysis of the cutaneous and respiratory tract absorption of anticholinesterases and the use of organophosphorus compounds as chemical warfare agents. The final parts are devoted to the toxicity of anticholinesterases to aquatic organisms. The book can provide useful information to toxicologists, doctors, students, and researchers.
This book provides a comprehensive history of police reform, charting its history from its origins in the early 18th century to the most recent examples in the 21st century of the Labour, Coalition and Conservative governments. Each key reform programme is explored in the social, political, and intellectual context of its time, how the necessary legislation was passed, how each programme was implemented, and what its legacy has been. This is the first study that concentrates on the key reforms that shaped the modern police service, their enduring legacies, and their underlying flaws. It is an essential read for police historians, criminologists, police academics, policy makers, and everyone interested in police history.
An international team of eminent atmospheric scientists have prepared Mechanisms of Atmospheric Oxidation of the Alkanes as an authoritative source of information on the role of alkanes in the chemistry of the atmosphere. The book includes the properties of the alkanes and haloalkanes, as well as a comprehensive review and evaluation of the existing literature on the atmospheric chemistry of the alkanes and their major atmospheric oxidation products, and the various approaches now used to model the alkane atmospheric chemistry. Comprehensive coverage is given of both the unsubstituted alkanes and the many haloalkanes. All the existing quality measurements of the rate coefficients for the reactions of OH, Cl, O(3P), NO3, and O3 with the alkanes, the haloalkanes, and their major oxidation products have been reviewed and evaluated. The expert authors then give recommendations of the most reliable kinetic data. They also review the extensive literature on the mechanisms and rates and modes of photodecomposition of the haloalkanes and the products of atmospheric oxidation of the alkanes and the haloalkanes, and make recommendations for future use by atmospheric scientists. The evaluations presented allow an extrapolation of the existing kinetic and photochemical data to those alkanes and haloalkanes that are as yet unstudied. The current book should be of special interest and value to the modelers of atmospheric chemistry as a useful input for development of realistic modules designed to simulate the atmospheric chemistry of the alkanes, their major oxidation products, and their influence on ozone and other trace gases within the troposphere.
For anyone who spends time in the backcountry, understanding not only what sorts of dangers you can run into out there but also exactly what those risks can do to you is part of being a smart, well informed outdoor traveler. In Lost and Stranded, author Timothy Sprinkle breaks down the perils that can befall hikers, hunters, and other outdoor enthusiasts. There are animal encounters, weather events (lightning strikes), parasites (giardia), biting insects (bees/wasps), winter hazards (avalanches), natural disasters (forest fires), hypothermia, dehydration, disorientation, and much, much more to worry about. Although these risks are generally well known, what’s less understood by many adventurers is what exactly happens to you when, say, you become malnourished in the backcountry. What does it feel like? How does the condition progress? How long do you generally have before the body shuts down? What helps or hurts when you’re fighting for survival? Lost and Stranded will answer these questions and many more by taking an inside look at more than two dozen outdoor hazards. Each one will include a narrative section that dramatizes the experience of a certain situation based on real-world events. From there, information from expert sources—medical doctors, first responders, wildlife experts, and others—will fill in the details around exactly how each scenario plays out on the ground, followed by suggestions on how to avoid or survive each risk factor, making this book is a vital resource for outdoor travelers.
When Tim McHenry first set eyes on Dixie, he sensed that his life would never be quite the same. Dixie had been hit by a car which resulted in the loss of her left front leg. She was given a second chance thanks to the compassion of a shelter director and the skill of a generous veterinarian. Tim adopted Dixie. Her rehabilitation became Tim’s responsibility. Little did he know that he would be the one who would soon need rescuing. Together, Tim and Dixie discovered that their extraordinary love would ultimately lead them on a path to redemption and give them both a leg to stand on.
Dynamic Physical Education for Secondary School Students provides PETE students a solid conceptual foundation for creating healthy learning environments and quality physical education programs. This resource offers a wide variety of units and activities that enhance learning.
On an epic voyage far beyond the Republic, the Jedi will confront their most extraordinary enemy—and test the limits of honor and sacrifice against their most devastating challenge. The Clone Wars have yet to erupt when Jedi Master Jorus C’baoth petitions the Senate for support of a singularly ambitious undertaking: the dream of Outbound Flight. Six Jedi Masters, twelve Jedi Knights, and fifty thousand men, women, and children will embark—aboard a gargantuan vessel, equipped for years of travel—on a mission to contact intelligent life and colonize undiscovered worlds beyond the known galaxy. Unknown to the famed Jedi Master, the launch of the mission is secretly being orchestrated by an unlikely ally: the evil Sith Lord Darth Sidious, who has his own reasons for wanting Outbound Flight to move forward. Yet Darth Sidious is not the mission’s most dangerous challenge. Once underway, the starship crosses paths at the edge of Unknown Space with the forces of the alien Chiss Ascendancy and a brilliant mastermind named Thrawn. Even Jedi knight Obi-Wan Kenobi, aboard Outbound Flight with his young Padawan student Anakin Skywalker, cannot help to avert disaster. What begins as a peaceful Jedi mission is violently transformed into an all-out war for survival against staggering odds—and the most diabolical of adversaries.
It began as the ultimate voyage of discovery only to become the stuff of lost Republic legend and a dark chapter in Jedi history. Zahn returns to tell the whole extraordinary story of the remarkable and doomed Outbound Flight Project.
The “riveting”* true story of the fiery summer of 1970, which would forever transform the town of Oxford, North Carolina—a classic portrait of the fight for civil rights in the tradition of To Kill a Mockingbird *Chicago Tribune On May 11, 1970, Henry Marrow, a twenty-three-year-old black veteran, walked into a crossroads store owned by Robert Teel and came out running. Teel and two of his sons chased and beat Marrow, then killed him in public as he pleaded for his life. Like many small Southern towns, Oxford had barely been touched by the civil rights movement. But in the wake of the killing, young African Americans took to the streets. While lawyers battled in the courthouse, the Klan raged in the shadows and black Vietnam veterans torched the town’s tobacco warehouses. Tyson’s father, the pastor of Oxford’s all-white Methodist church, urged the town to come to terms with its bloody racial history. In the end, however, the Tyson family was forced to move away. Tim Tyson’s gripping narrative brings gritty blues truth and soaring gospel vision to a shocking episode of our history. FINALIST FOR THE NATIONAL BOOK CRITICS CIRCLE AWARD “If you want to read only one book to understand the uniquely American struggle for racial equality and the swirls of emotion around it, this is it.”—Milwaukee Journal Sentinel “Blood Done Sign My Name is a most important book and one of the most powerful meditations on race in America that I have ever read.”—Cleveland Plain Dealer “Pulses with vital paradox . . . It’s a detached dissertation, a damning dark-night-of-the-white-soul, and a ripping yarn, all united by Tyson’s powerful voice, a brainy, booming Bubba profundo.”—Entertainment Weekly “Engaging and frequently stunning.”—San Diego Union-Tribune
When in 1550 Andreas Osiander (1498-1552) advocated a different understanding of the central Lutheran doctrine of justification by faith alone, most other Lutheran churches in Germany rejected his stance, producing nearly one hundred opposing tracts. Timothy J. Wengert examines these reactions as a way of describing the theological side of confessionalization in Lutheran lands.--Back of dust jacket.
Before Jackie Robinson integrated major league baseball in 1947, black and white ballplayers had been playing against one another for decades—even, on rare occasions, playing with each other. Interracial contests took place during the off-season, when major leaguers and Negro Leaguers alike fattened their wallets by playing exhibitions in cities and towns across America. These barnstorming tours reached new heights, however, when Satchel Paige and other African- American stars took on white teams headlined by the irrepressible Dizzy Dean. Lippy and funny, a born showman, the native Arkansan saw no reason why he shouldn’t pitch against Negro Leaguers. Paige, who feared no one and chased a buck harder than any player alive, instantly recognized the box-office appeal of competing against Dizzy Dean’s "All-Stars." Paige and Dean both featured soaring leg kicks and loved to mimic each other’s style to amuse fans. Skin color aside, the dirt-poor Southern pitchers had much in common. Historian Timothy M. Gay has unearthed long-forgotten exhibitions where Paige and Dean dueled, and he tells the story of their pioneering escapades in this engaging book. Long before they ever heard of Robinson or Larry Doby, baseball fans from Brooklyn to Enid, Oklahoma, watched black and white players battle on the same diamond. With such Hall of Fame teammates as Josh Gibson, Turkey Stearnes, Mule Suttles, Oscar Charleston, Cool Papa Bell, and Bullet Joe Rogan, Paige often had the upper hand against Diz. After arm troubles sidelined Dean, a new pitching phenom, Bob Feller—Rapid Robert—assembled his own teams to face Paige and other blackballers. By the time Paige became Feller’s teammate on the Cleveland Indians in 1948, a rookie at age forty-two, Satch and Feller had barnstormed against each other for more than a decade. These often obscure contests helped hasten the end of Jim Crow baseball, paving the way for the game’s integration. Satchel Paige, Dizzy Dean, and Bob Feller never set out to make social history—but that’s precisely what happened. Tim Gay has brought this era to vivid and colorful life in a book that every baseball fan will embrace.
Mara Jade is beautiful, intelligent--and deadly! She is the Emperor's Hand, the personal assassin of the Empire's dark overlord. Her final mission: the assassination of the leader of the Black Nebula crime organization.
Timothy has struck again! This time he offers over 50 short stories, of various lengths, to entertain his readers on a roller coaster ride of imagination. The tales within are from Westerns to Fantasies and beyond. All ages are invited to take a step forward into this realm of the minds eye, explore past the Forest Tree Doorway. Come on in - if you dare!! But remember: youre entering at your own risk!!!
The goal of the O'Leary Series is to give students a basic understanding of computing concepts and to build the skills necessary to ensure that an O'Leary student has an advantage in whatever career they choose. The text design emphasizes step-by-step instructions with full screen captures that illustrate the results of each step performed. This method allows students to learn at their own pace. Each Tutorial (chapter) combines conceptual coverage with detailed software-specific instructions. A running case that is featured in each tutorial highlights the real-world applications of each software program and leads students step-by-step from problem to solution.
Everything Jack Aiello does is for himself. A 'smash mouth' from Brooklyn, Jack is addicted, aimless, obsessed with women and drink. That is until the notorious Brandis brothers send him on a job to locate the criminal brothers' only nephew who has disappeared somewhere around Burlington, Vermont. He sees the job as a chance to sober up and start over. But just as Jack begins to get a taste of the good life he's been craving, he also begins to realize that he can never have it. Mad biochemists, government conspiracies, double agents, and religious crusaders await Jack as he falls deeper into the rabbit hole in Vermont's Northern Kingdom. From self-absorbed alcoholic to gun-wielding sleuth, Jack finally becomes what we all must, eventually, should we want to achieve our highest self: a man willing to die for that which is most precious to him. (Copy by Geoffrey Pierce)
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