Elemene Antitumor Drugs: Molecular Compatibility Theory and its Applications in New Drug Development and Clinical Practice introduces natural anti-tumor drug elemene and systematic basic and clinical research. Basic principles of the compatibility theory of traditional Chinese medicine and the research and development process of the natural anti-tumor drug elemene under the guidance of this principle are introduced. In addition, the traditional extraction and separation of elemene and the new biosynthesis technology developed by the author's team are described. Then, the systematic anti-tumor mechanism research of elemene are introduced, including unique multi-target and comprehensive anti-tumor mechanisms and detailed mechanisms for treating specific tumors. Under the guidance of compatibility theory, clinical research on the combined application of elemene and different chemotherapeutic drugs has been further carried out, achieving positive results in clinical practice. Finally, the book also introduces the research and exploration of new drug delivery systems of elemene, as well as the structural modification and drug discovery progress taking elemene structure as the lead compound. - Systematically introduces the principles of molecular compatibility theory and its application in new drug development and clinical practice - Provides comprehensive information on drug development, drug preparation, mechanism study and clinical research of the natural antitumor drug elemene - Includes valuable experience in drug development and related industry chain construction based on natural products - Introduces clinical research ideas and experiences for expanding clinical indications - Presents the practical methods and research experience of the secondary development of traditional Chinese medicine
The Liang dynasty (502-557) is one of the most brilliant and creative periods in Chinese history and one of the most underestimated and misunderstood. Under the Liang, literary activities, such as writing, editing, anthologizing, and cataloguing, were pursued on an unprecedented scale, yet the works of this era are often dismissed as "decadent" and no more than a shallow prelude to the glories of the Tang. This book is devoted to contextualizing the literary culture of this era--not only the literary works themselves but also the physical process of literary production such as the copying and transmitting of texts; activities such as book collecting, anthologizing, cataloguing, and various forms of literary scholarship; and the intricate interaction of religion, particularly Buddhism, and literature. Its aim is to explore the impact of social and political structure on the literary world.
As medieval Chinese manuscripts were copied and recopied through the centuries, both mistakes and deliberate editorial changes were introduced. Xiaofei Tian shows how readers not only experience authors but "produce" them by shaping texts to their interpretation, focusing on the evolution over the centuries of the reclusive poet Tao Yuanming into a figure of epic stature.
An endless expanse of blue, sea, withered wood, immortal mountains, ten thousand miles in total without any sign of human habitation. Endless rays of blue, boundless sea, dead wood, immortal mountains, ten thousand miles devoid of human habitation.
The turn of the third century CE—known as the Jian’an era or Three Kingdoms period—holds double significance for the Chinese cultural tradition. Its writings laid the foundation of classical poetry and literary criticism. Its historical personages and events have also inspired works of poetry, fiction, drama, film, and art throughout Chinese history, including Internet fantasy literature today. There is a vast body of secondary literature on these two subjects individually, but very little on their interface.The image of the Jian’an era, with its feasting, drinking, heroism, and literary panache, as well as intense male friendship, was to return time and again in the romanticized narrative of the Three Kingdoms. How did Jian’an bifurcate into two distinct nostalgias, one of which was the first paradigmatic embodiment of wen (literary graces, cultural patterning), and the other of wu (heroic martial virtue)? How did these largely segregated nostalgias negotiate with one another? And how is the predominantly male world of the Three Kingdoms appropriated by young women in contemporary China? The Halberd at Red Cliff investigates how these associations were closely related in their complex origins and then came to be divergent in their later metamorphoses.
coincidence, zhou yi seventeen years old, miss the girls, you still want to run? this world, will be able to stop the killing, god to kill god! this world, only willing to live up to the dust not qing, the sky again!
coincidence, zhou yi seventeen years old, miss the girls, you still want to run? this world, will be able to stop the killing, god to kill god! this world, only willing to live up to the dust not qing, the sky again!
He was just trying to swindle his way in, but with an open mouth, he directly became the Tang Clan's Eldest Young Miss's fiancé and was even a son-in-law. Li Mingyi expressed that this son-in-law was really ... Don't be too good! In front of him, there was his impeccable fiancée, his fiery hot little chili who kept bickering with him, and even his sister-in-law who shared a room with him ...
coincidence, zhou yi seventeen years old, miss the girls, you still want to run? this world, will be able to stop the killing, god to kill god! this world, only willing to live up to the dust not qing, the sky again!
He was the king of the legends of the underground mercenaries. Because he had stolen the most precious jade of the world's top organization, the Rose Pavilion, and was seriously injured by the Rose Pavilion Master, he was forced to hide in the Flower City, disguised as a rogue hawker to sell cucumbers in front of different companies ...
Picking up a Barbie, she happily carried it back to her dorm, as if it was her daughter's ... But, who can tell me what's going on with the arrogant ghost sitting across from me! You gave my daughter back to me, ah ah ah ah!
This book explores the parallel and yet profoundly different ways of seeing the outside world and engaging with the foreign at two important moments of dislocation in Chinese history, namely, the early medieval period commonly known as the Northern and Southern Dynasties (317–589 CE), and the nineteenth century. Xiaofei Tian juxtaposes literary, historical, and religious materials from these two periods in comparative study, bringing them together in their unprecedentedly large-scale interactions, and their intense fascination, with foreign cultures. By examining various cultural forms of representation from the two periods, Tian attempts to sort out modes of seeing the world that inform these writings. These modes, Tian argues, were established in early medieval times and resurfaced, in permutations and metamorphoses, in nineteenth-century writings on encountering the Other. This book is for readers who are interested not only in early medieval or nineteenth-century China but also in issues of representation, travel, visualization, and modernity.
This book explores three discharged Ming officials in the sixteenth century--Wang Jiusi, Kang Hai, and Li Kaixian--who turned to literary endeavors when forced to retire. As their efforts reveal, a disappointing end to an official career and a physical move away from the center led to their embrace and pursuit of a marginalized literary genre, qu.
A small white European building is located in the western part of the French Concession. No one knows when or who built this little house, and the old people who live around here say that it was there from the moment they could remember.The owners of the houses changed several times, all moving away for some unknown reason. In the end, they became ownerless houses, and after a while, there were rumors of ghosts. This foreign building slowly became a 'haunted house'.Until five years ago, a girl with a white umbrella was seen lugging heavy luggage inside, but no one had seen her leave the building. At night, it was even darker inside the building. Only the faint sounds of the piano could be heard occasionally during the day ...Since then, no one dared to approach this place.
The king of this generation undid his armor and returned to the field, becoming a beautiful CEO's bodyguard. He had wanted to be a small bodyguard in peace, but one beauty after another came rushing towards him. Life had also changed dramatically ...
She, who was born before her marriage, turned into a complete slut with the contempt and curses of the entire world. That damn stinky man ate her whole body, yet did not show himself. That night, she could still vaguely remember how he robbed and occupied her, how his neck interweaved with her hot body and his tempting breathing.
She, who was born before her marriage, turned into a complete slut with the contempt and curses of the entire world. That damn stinky man ate her whole body, yet did not show himself. That night, she could still vaguely remember how he robbed and occupied her, how his neck interweaved with her hot body and his tempting breathing.
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