Breed Predispositions to Disease in Dogs and Cats, Third Edition provides a comprehensive exploration of current knowledge of breed predispositions based on rigorous examination of primary research. Incorporates the latest research, new testing methods, and newly-discovered predispositions and diseases Provides expanded information on genetics, epidemiology, and longevity Includes key characteristics of diseases, including pathogenesis, genetics, risks, and common presentations Indexes dogs and cats by breed, with listings of common inherited and predisposed disorders organized by body system Includes absolute and relative frequency/occurrence data for conditions, along with references to further information
This timely reference presents, for the first time, new findings in molecular genetics that are applicable to the epidemiology, pathogenesis, neuropathology, clinical features, and management of ataxia-bridging the gap between scientific and clinical practice. Organized by the distinctive ataxia disorders, their pathogenesis, and management-facilitating quick and efficient diagnoses! Providing complementary sections on the anatomy of the spinocerebellar system, its normal function, and a history of ataxia research and management, the Handbook of Ataxia Disorders clarifies the impact of identifying the molecular causes of ataxia offers in-depth analysis of dominant and recessive and nonhereditary ataxia disorders explores the vital connection between the genotypes and phenotypes of various degenerative ataxia disorders and more! Written by more than 60 international experts and supplemented with over 2600 literature references, photographs, micrographs, drawings, and tables, the Handbook of Ataxia Disorders is an essential and useful reference for clinical neurologists and neuropathologists, neuropediatricians, geneticists, physiatrists, and medical school students in these disciplines.
Connect inquiry to improved teaching and learning across your district! Now that federal and state initiatives require school districts to provide job-embedded professional development, the next step is making it happen. This book helps districts define, develop, and implement a systematic inquiry-based process with a laser-like focus on both adult and student learning. This book′s inquiry model challenges educators and students to: Define questions they are passionate about exploring Collect and analyze data to inform their questions Share what they have learned through the process with others Collaborate to build on their results and improve student achievement The authors′ award-winning school improvement program, featured in the text, offers a fresh look at how to improve the quality of teaching and learning across a district. Administrators, teachers, and students will find an invaluable road map for tackling real-world challenges and taking control of their own learning.
Featuring more than 1,200 illustrations, including over 800 in full color, this book presents a stepwise approach to the surgical management of the most challenging cases in diabetic limb salvage. The book covers acute and chronic diabetic foot and ankle wounds and guides surgical decision-making in different case scenarios, including prophylactic, elective, trauma, and revisional surgery. Emphasis is on the multidisciplinary team approach. Topics covered include surgical reconstruction of the acute and chronic Charcot foot and ankle; local random, muscle and pedicle flaps for soft tissue coverage of the diabetic foot; equinus deformity and the diabetic foot; surgical management of malunions and nonunions; and autogeneous bone grafting and orthobiologics.
The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today's students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time. - Clearly written format incorporates rich illustrations, diagrams, and charts. - Uses real examples to illustrate key cell biology concepts. - Includes beneficial cell physiology coverage. - Clinically oriented text relates cell biology to pathophysiology and medicine. - Takes a mechanistic approach to molecular processes. - Major new didactic chapter flow leads with the latest on genome organization, gene expression and RNA processing. - Boasts exciting new content including the evolutionary origin of eukaryotes, super resolution fluorescence microscopy, cryo-electron microscopy, gene editing by CRISPR/Cas9, contributions of high throughput DNA sequencing to understand genome organization and gene expression, microRNAs, IncRNAs, membrane-shaping proteins, organelle-organelle contact sites, microbiota, autophagy, ERAD, motor protein mechanisms, stem cells, and cell cycle regulation. - Features specially expanded coverage of genome sequencing and regulation, endocytosis, cancer genomics, the cytoskeleton, DNA damage response, necroptosis, and RNA processing. - Includes hundreds of new and updated diagrams and micrographs,plus fifty new protein and RNA structures to explain molecular mechanisms in unprecedented detail. - Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and over a dozen animations from the book on a variety of devices.
Several books have been published on scaling in biology and its ramifications in the animal kingdom. However, none has specifically examined the multifaceted effects of how changes in human height create disproportionately larger changes in weight, surface area, strength and other physiological parameters. Yet, the impact of these non-linear effects on individual humans as well as our world's environment is enormous. Since increasing human body size has widespread ramifications, this book presents findings on the human species and its ecological niche. its community and how the species interacts with its environment. Thus, a few chapters provide an ecological overview of how increasing human body size relates to human evolution, fitness, health, survival and the environment. This book provides a unique purview of the laws of scaling on human performance, health, longevity and the environment. Numerous examples from various research disciplines are used to illustrate the impact of increasing body size on many aspects of human enterprises, including work output, athletics and intellectual performance.
The 200-year-old Butler's Lives of the Saints has undergone a thorough revision and rewriting and is now presented as a 12-volume set categorized according to months of the year. This volume includes those saints commemorated in November.
Annotation The field of molecular biology has revolutionized the study of biology. The applications to medicine are enormous, ranging from diagnostic techniques for disease and genetic disorders, to drugs, to gene therapy. Focusing on the fundamentals of molecular biology and encompassing all aspects of the expression of genetic information, the Encyclopedia of Molecular Biology will become the first point of reference for both newcomers and established professionals in molecular biology needing to learn about any particular aspect of the field.
Offering today's most authoritative, comprehensive coverage of sleep disorders, Kryger's Principles and Practice of Sleep Medicine, 7th Edition, is a must-have resource for sleep medicine specialists, fellows, trainees, and technicians, as well as pulmonologists, neurologists, and other clinicians who see patients with sleep-related issues. It provides a solid understanding of underlying basic science as well as complete coverage of emerging advances in management and treatment for a widely diverse patient population. Evidence-based content, hundreds of full-color illustrations, and a wealth of additional resources online help you make well-informed clinical decisions and offer your patients the best possible care. - Contains new chapters on sleep in intersex and transgender individuals; sleep telemedicine and remote PAP adherence monitoring; and sleep and the menstrual cycle, as well as increased coverage of treatment and management of pediatric patients. - Includes expanded sections on pharmacology, sleep in individuals with other medical disorders, and methodology. - Discusses updated treatments for sleep apnea and advancements in CPAP therapy. - Offers access to 95 video clips online, including expert interviews and sleep study footage of various sleep disorders. - Meets the needs of practicing clinicians as well as those preparing for the sleep medicine fellowship examination or recertification exams, with more than 950 self-assessment questions, answers, and rationales online. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Advances in technology, such as MP3 players, the Internet and DVDs, have led to the production, storage and distribution of a wealth of audio signals, including speech, music and more general sound signals and their combinations. MPEG-7 audio tools were created to enable the navigation of this data, by providing an established framework for effective multimedia management. MPEG-7 Audio and Beyond: Audio Content Indexing and Retrieval is a unique insight into the technology, covering the following topics: the fundamentals of MPEG-7 audio, principally low-level descriptors and sound classification and similarity; spoken content description, and timbre, melody and tempo music description tools; existing MPEG-7 applications and those currently being developed; examples of audio technology beyond the scope of MPEG-7. Essential reading for practising electronic and communications engineers designing and implementing MPEG-7 compliant systems, this book will also be a useful reference for researchers and graduate students working with multimedia database technology.
This book presents a collection of thirteen essays by one of America's great academic accountants, Carl Devine. The essays explore in substantial depth the evolution of Professor Devine's philosophy, research, and thinking during his nearly sixty years of study. The extent of his knowledge spans a variety of disciplines from science and mathematics to philosophy and religion. This eclectic collection of essays is continuously rewarding, and with even a cursory review one quickly discovers the richness and breadth of Devine's work. This book will be an invaluable historical and scholarly legacy to future generation of accounting students and educators. In them Professor Devine reflects objectively on some of the personalities in, and development of accounting and accounting thought during two momentous generations in which a revolution has occurred in accounting research and in the accounting/auditing professions.
A comprehensive book on collecting & repairing antique clocks or timepieces written for both the amateur or experienced in mind. How to tell what's wrong, What tools to use, where to get parts and how to fit them, using hundreds of photographs and diagrams making repairs within most peoples reach, a separate section deals with sympathetic restoration of the case. The Trademarks section includes thousands of clockmakers marks from all around the world, usually stamped on the movement itself enabling the reader to accurately not only identify the maker but date and value the clock.
Textbook on the fundamentals of pl-i computer language and its applications in a variety of information processing tasks relating to non-numeric information retrieval in library science and information science areas - includes an introduction to the basic concepts of boolean algebra.
In spite of the diverse opportunities to participate in various forms of exercise at the workplace & during leisure time, the number of young people who have pain in the locomotive apparatus of the body is increasing. Apparently, many of the forms of exercise offered do not take into account either the individual level of fitness, sensible energetics, or a balance of agility, strength & stamina. This guide arose out of this realization & turned years of experience in manual medicine, physical therapy, rehabilitation, & sports medicine into a systematically structured exercise program. The theoretical foundations, relevant experimental procedures & the basic concept of therapy of limited mobility in the form of mobilization & stretching are discussed. However, the focus is on at-home exercise strategies which include the doctor or physical therapist as a mediating "trainer" in an advisory & supervisory role.
An evidence-based reference for integrating manual medicine into everyday clinical practice Written by the authors of the popular Manual Medicine: Diagnostics and Manual Medicine: Therapy, this book is a comprehensive guide to integrating manual medicine into the diagnosis and clinical management of musculoskeletal disorders and pain syndromes. Brimming with instructive images and illustrations, the book provides a solid foundation in general principles of manual medicine, spinal biomechanics, neurophysiology, as well as treatments for each disorder and condition. Separate sections on the spine, limbs, and muscles present clinical applications for structural diagnosis and functional treatment. Highlights: Practical examples of evidence-based approaches to manual medicine 1,313 illustrations and photographs of superb quality that rapidly demonstrate key concepts Coverage of the essentials of the neuro-musculoskeletal examination with step-by-step descriptions of the techniques for observation, palpation, motion tests, functional examination, and provocative tests, including quick screening tests Chapter on the various components of nonradicular pain syndromes, including muscle pain syndromes, with clear diagnostic criteria for distinguishing the non-radicular and soft-tissue pain syndromes from other pain syndromes Succinct descriptions of common clinical neuro-orthopedic disorders and syndromes of the spine, upper limb, and lower limb in tabular format - ideal for rapid reference and review Discussion of the rationale for selecting particular low-risk treatment interventions, as well as a thorough discussion of indications and contraindications for patients with potentially increased risk Discussion of important considerations for documentation, informed consent, patient monitoring, and follow-up measures Practical section with descriptions of exercises for patients to do on their own Potential considerations for future research This book will serve as the definitive reference for all practitioners involved in the diagnosis and medical management of locomotor disorders and painful conditions. It will enable clinicians to enhance their diagnostic and treatment armamentarium by incorporating manual medicine techniques based on the current, evidence-based knowledge of the interrelationships between structure and function.
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