Thomas R. Pellegrino's Books

Moon Lander

How We Developed the Apollo Lunar Module

By: Thomas J. Kelly

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Moon Lander

How We Developed the Apollo Lunar Module

By: Thomas J. Kelly

Chief engineer Thomas J. Kelly gives a firsthand account of designing, building, testing, and flying the Apollo lunar module. It was, he writes, “an aerospace engineer’s dream job of the century.” Kelly’s account begins with the imaginative process of sketching solutions to a host of technical challenges with an emphasis on safety, reliability, and maintainability. He catalogs numerous test failures, including propulsion-system leaks, ascent-engine instability, stress corrosion of the aluminum alloy parts, and battery problems, as well as their fixes under the ever-present constraints of budget and schedule. He also recaptures the exhilaration of hearing Apollo 11’s Neil Armstrong report that “The Eagle has landed,” and the pride of having inadvertently provided a vital “lifeboat” for the crew of the disabled Apollo 13.

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Page Count

304

Publisher

Smithsonian Institution

Published Date

ISBN 10

1588343618

ISBN 13

9781588343611

Did Jesus Really Rise from the Dead?

A Surgeon-Scientist Examines the Evidence

By: Thomas A. Miller

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Did Jesus Really Rise from the Dead?

A Surgeon-Scientist Examines the Evidence

By: Thomas A. Miller

How can a respected scientist believe in the resurrection? Can I trust the Bible’s account that Jesus actually rose from the dead? If the resurrection really occurred, of what importance is it to you and me? Our ready embrace of the authority of science has left many doubting that Jesus’s resurrection was a verifiable, historical event. Yet Thomas Miller, an experienced scientist and well-respected surgeon, challenges the notion that modern medicine has disproved the possibility of the resurrection. Through careful investigation of the evidence and evaluation of its reliability, Dr. Miller demonstrates that science and religion are not incompatible and makes a compelling case for the reality of the resurrection.

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Page Count

176

Publisher

Wipf and Stock Publishers

Published Date

ISBN 10

1666742236

ISBN 13

9781666742237

Cancer Genomics

Chapter 20. Genomic Basis of Pediatric Lymphomas

By: Nathanael G. Bailey,Thomas Gross,Megan S. Lim

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Cancer Genomics

Chapter 20. Genomic Basis of Pediatric Lymphomas

By: Nathanael G. Bailey,Thomas Gross,Megan S. Lim

Lymphomas account for approximately 10% of childhood malignancies. Pediatric lymphomas are typically aggressive: lymphoblastic lymphoma, Burkitt lymphoma (BL), diffuse large B-cell lymphoma (DLBCL), and anaplastic large cell lymphoma (ALCL) are among the most common pediatric lymphoma subtypes. The genetic basis of these neoplasms is beginning to be understood. Lymphoblastic lymphomas arise through a variety of genetic pathways, dependent upon B- or T-progenitor origin. Aggressive B-cell lymphomas (BL and DLBCL) commonly arise secondary to errors that occur during physiologic B-cell development. BL is characterized by MYC translocation with an immunoglobulin locus enhancer. This lesion may also be present in DLBCL, particularly in children, but DLBCLs often have mutations of a variety of other genes, such as BCL6. DLBCL may be separated into germinal center B-cell-like (GCB) and activated B-cell-like groups. Pediatric DLBCL are more commonly in the GCB category than are adult DLBCL. Adult DLBCL has a tendency toward increased genomic complexity compared with pediatric DLBCL. ALCL is a T-cell lymphoma that is typically characterized by ALK fusions, most commonly with NPM. Genomic profiling has identified areas of recurrent genetic gains and losses in ALCL. Understanding the underlying genetic basis of lymphoma provides hope for the development of more targeted therapies for this group of diseases. However, further investigation of the lymphoma genome is necessary, particularly in pediatric patients.

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Publisher

Elsevier Inc. Chapters

Published Date

ISBN 10

0128061170

ISBN 13

9780128061176

On Time and On Budget: Project Management Collection (4 Books)

By: Harvard Business Review,Joe Knight,Roger Thomas,Brad Angus,Aaron J. Shenhar

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On Time and On Budget: Project Management Collection (4 Books)

By: Harvard Business Review,Joe Knight,Roger Thomas,Brad Angus,Aaron J. Shenhar

The Harvard Business Review Project Management Collection is for anyone serious about project management. Project Management for Profit shows every company owner and project manager—at businesses large and small—how to run projects differently. Reinventing Project Management, based on an unprecedented study of more than 600 projects in a variety of businesses and organizations around the globe, provides a new and highly adaptive model for planning and managing projects to achieve superior business results. Also included in this collection are Managing Projects Large and Small, which will walk you through every step of project oversight from start to finish, and the HBR Guide to Project Management, which will help you: build a strong, focused team, break major objectives into manageable tasks, create a schedule that keeps all the moving parts under control, monitor progress toward your goals, manage stakeholders' expectations, and wrap up your project and gauge its success.

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Page Count

1399

Publisher

Harvard Business Review Press

Published Date

ISBN 10

1633691608

ISBN 13

9781633691605

Book's by Thomas R. Pellegrino

Moon Lander

Moon Lander

Did Jesus Really Rise from the Dead?

Did Jesus Really Rise from the Dead?

Cancer Genomics

Cancer Genomics

On Time and On Budget: Project Management Collection (4 Books)

On Time and On Budget: Project Management Collection (4 Books)

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