Thomas Nogrady's Books

Medicinal Chemistry

A Molecular and Biochemical Approach

By: Thomas Nogrady,Donald F. Weaver

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Medicinal Chemistry

A Molecular and Biochemical Approach

By: Thomas Nogrady,Donald F. Weaver

Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.

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664

Publisher

Oxford University Press

Published Date

ISBN 10

0190282967

ISBN 13

9780190282967

Thomas Clarkson and Ottobah Cugoano

Essays on the Slavery and Commerce of the Human Species

By: Thomas Clarkson,Ottobah Cugoano

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Thomas Clarkson and Ottobah Cugoano

Essays on the Slavery and Commerce of the Human Species

By: Thomas Clarkson,Ottobah Cugoano

When abolitionists Thomas Clarkson and Ottobah Cugoano published their essays on slavery in the late eighteenth century, they became key participants in one of the most important human rights campaigns in history. British abolitionism sought to expose the realities of transatlantic slavery in addition to asking politicians to help dehumanized Africans in the New World, and this edition brings together two major essays of the 1780s that were influential in the spread of the early abolitionist movement: Clarkson’s An Essay on the Slavery and Commerce of the Human Species and Cugoano’s Thoughts and Sentiments on the Evil and Wicked Traffic of the Slavery and Commerce of the Human Species. A critical introduction and extensive historical appendices on British and American slavery and abolitionism, featuring contemporary arguments for and against slavery, are also included.

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Page Count

427

Publisher

Broadview Press

Published Date

ISBN 10

1551113384

ISBN 13

9781551113388

Bite Size Advice 2

The Lesson Continues ... A Further Guide to Political,Economic, Social and Technological Issues

By: Paul J. Thomas

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Bite Size Advice 2

The Lesson Continues ... A Further Guide to Political,Economic, Social and Technological Issues

By: Paul J. Thomas

Financial services CEO, Paul Thomas, made his debut as an author with Bite Size Advice - A Definitive Guide to Political, Economic, Social and Technological Issues. Now he is back with volume 2. This second installment of Bite Size Advice has the subtitle, The Lesson Continues, and is a veritable treasure trove for those with a thirst for knowledge. Yet again, the reader is presented with a collection of blog posts that provide an illuminating guide to the issues that are shaping politics, redesigning business, changing society and driving technology. Prepare to be educated, entertained and enlightened as you discover concise answers to important questions. IS government debt a bad thing?WHAT caused the Global Financial Crisis?WHERE is artificial intelligence headed?WHY is higher education important?HOW vital is banking to a modern economy?WILL driverless cars become ubiquitous? This is a practical guide that immediately takes hold of the reader’s inquisitive nature. Thoroughly engaging and brimming with information, barely a page goes by without an interesting fact. The snappy text is presented in bite-size nuggets and moves effortlessly from topic to topic. Paul offers a fresh voice, honest opinions and concise thinking as he skilfully examines some of today’s most topical issues. The writing is lucid while simultaneously being witty and wise. A must read for anyone who wants to understand how the world works.

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Page Count

304

Publisher

Made For Success Publishing

Published Date

ISBN 10

1613398700

ISBN 13

9781613398708

Obligations in Roman Law

Past, Present, and Future

By: Thomas McGinn

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Obligations in Roman Law

Past, Present, and Future

By: Thomas McGinn

Explores a fundamental building block of Roman life

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377

Publisher

University of Michigan Press

Published Date

ISBN 10

0472118439

ISBN 13

9780472118434

Stocker and Dehner's Pediatric Pathology

By: Aliya N. usain,J. Thomas Stocker,Louis P. Dehner

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Stocker and Dehner's Pediatric Pathology

By: Aliya N. usain,J. Thomas Stocker,Louis P. Dehner

Effectively diagnose the complete range of pediatric pathologies, from neonatal disorders through adolescence. Intended for a broad audience including general and pediatric pathologists, pediatricians, surgeons, oncologists, and other pediatric subspecialties, Stocker & Dehner’s Pediatric Pathology is widely recognized as the definitive go-to comprehensive clinical reference in the unique subspecialty of pediatric pathology – which, unlike other subspecialties, is defined by an age group rather than an organ system or process. The tumors that occur in infants and children are distinct from those that develop in adults, and they often exhibit exceptional clinical behavior, thus requiring different diagnostic and therapeutic protocols. Authored by a host of prominent authorities on this challenging area, the fourth edition of Stocker & Dehner’s Pediatric Pathology was designed to be a comprehensive volume on all major aspects of the pathologic anatomy of childhood disorders, providing the in-depth, richly illustrated guidance you need to confidently evaluate and dependably report your findings. Sweeping updates in this edition put all of the very latest knowledge and techniques at your fingertips.

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4089

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1496326911

ISBN 13

9781496326911

Retouching Stalin's Moustache

By: Thomas P. Muhl

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Retouching Stalin's Moustache

By: Thomas P. Muhl

Retouching Stalin’s Moustache is the story of a talented artist, survivor of twentieth century Europe under both fascism and communism, who is coping with survival in America in a life complicated by further twists and turns of fate. The narrative moves from flashback to foreground, describing his early marriage and escape from the Old World. It follows up with more recent adventures, the dissolution of his marriage and newly created layers of memory. This book shows how a “permanently displaced person” must struggle to seek out means of adjusting to the daylight world of today.

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Page Count

364

Publisher

Xlibris Corporation

Published Date

ISBN 10

1456894811

ISBN 13

9781456894818

Climate Change

An Interdisciplinary Introduction

By: Thomas Brewer

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Climate Change

An Interdisciplinary Introduction

By: Thomas Brewer

This textbook introduces and explains the issues around climate change and its mitigation. It includes topics across disciplines and can be used as a single-volume text by students studying a range of subjects. Among the topics included are: ·How to adopt significant mitigation measures now to avoid the most catastrophic long-term consequences of climate change. ·Reducing the rates of highly potent, short-lived emissions of methane gas and black carbon particulates—reductions that are necessary to meet the temperature targets of the Paris Agreements. ·Implementing wide-ranging adaptation measures to reduce the deaths and economic costs of extreme heat waves, droughts, wildfires, hurricanes, and floods. ·Recognizing the unusually rapid warming in the Arctic, which is disrupting weather patterns in the northern hemisphere and currents in the Atlantic Ocean, causing world-wide sea-level rise, and also causing methane leaks in the Arctic region—leaks that could eventually lead to irreversible global warming consequences. Meeting these challenges effectively requires action by both governments and businesses. The book examines the national and local governmental policies—and business practices—that are needed in sector-specific chapters. An objective of the book is to inform readers about specific problems resulting from climate change—and the wide range of potential government policies and business practices, changes in technologies, and changes in public attitudes and actions that can reduce the emissions and otherwise lessen their impacts. Indeed, a central message is that understanding the issues posed by climate change requires no less than an understanding of climate science, micro- and macro-economics, technologies for mitigation and adaptation measures, as well as politics and law at many governmental levels from local to global. The author has included short case studies that illustrate and integrate multiple analytic perspectives. The book is therefore appropriate for students, professionals, and general audiences with wide-ranging interests and backgrounds.

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Page Count

228

Publisher

Springer Nature

Published Date

ISBN 10

3031429060

ISBN 13

9783031429064

Canadian Geography

A Scholarly Bibliography

By: Thomas A. Rumney

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Canadian Geography

A Scholarly Bibliography

By: Thomas A. Rumney

Canadian Geography: A Scholarly Bibliography is a compendium of published works on geographical studies of Canada and its various provinces. It includes works on geographical studies of Canada as a whole, on multiple provinces, and on individual provinces. Works covered include books, monographs, atlases, book chapters, scholarly articles, dissertations, and theses. The contents are organized first by region into main chapters, and then each chapter is divided into sections: General Studies, Cultural and Social Geography, Economic Geography, Historical Geography, Physical Geography, Political Geography, and Urban Geography. Each section is further sub-divided into specific topics within each main subject. All known publications on the geographical studies of Canada—in English, French, and other languages—covering all types of geography are included in this bibliography. It is an essential resource for all researchers, students, teachers, and government officials needing information and references on the varied aspects of the environments and human geographies of Canada.

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Page Count

801

Publisher

Scarecrow Press

Published Date

ISBN 10

0810867184

ISBN 13

9780810867185

Advanced Therapy in Facial Plastic and Reconstructive Surgery

By: J. Regan Thomas

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Advanced Therapy in Facial Plastic and Reconstructive Surgery

By: J. Regan Thomas

A comprehensive coverage of facial and reconstructive surgery written by nationally known plastic surgeons from around the US who explain the most current updated clinical techniques and reflect their own clinical experience and preferences. Includes extraordinary clinical and surgical photos and case studies from these authors' practices. Coverage includes the full spectrum of cosmetic-aesthetic procedures and reconstructive procedures including congenital abnormalities, facial trauma, cancer and special chapters on Scar Revision and Camouflage surgery, grafts and implants, laser surgery and wound healing. This text will be of great value to both experienced surgeons and resident level physicians.

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822

Publisher

PMPH-USA

Published Date

ISBN 10

1607950111

ISBN 13

9781607950110

General Thoracic Surgery

By: Thomas W. Shields,Joseph LoCicero,Carolyn E. Reed,Richard H. Feins

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General Thoracic Surgery

By: Thomas W. Shields,Joseph LoCicero,Carolyn E. Reed,Richard H. Feins

Long considered the bible of thoracic surgery, this comprehensive two-volume textbook guides you through virtually every open and endoscopic surgical technique with expert commentary by the leaders in thoracic surgery from around the world. Coverage includes extensive sections on lung cancer and other pulmonary tumors. All facets of thoracic disease are covered from anatomy and embryology to diagnostics, including extensive radiological sections. Multidisciplinary contributions on medical treatment, radiation oncology, and surgery and anesthesia are included. Highlights include new material on minimally invasive procedures and thoroughly updated diagnostic and treatment information. Operative checklists are included in procedural chapters, and procedures are presented as bulleted to-do lists wherever possible. A companion Website will offer the fully searchable text with all images and video clips of selected procedures.

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2664

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1451152787

ISBN 13

9781451152784

Medicinal Chemistry

A Molecular and Biochemical Approach

By: Thomas Nogrady,Donald F. Weaver

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Medicinal Chemistry

A Molecular and Biochemical Approach

By: Thomas Nogrady,Donald F. Weaver

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Solve jigsaw puzzle

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Page Count

664

Publisher

Oxford University Press

Published Date

ISBN 10

0198026455

ISBN 13

9780198026457

Book's by Thomas Nogrady

Medicinal Chemistry

Medicinal Chemistry

Thomas Clarkson and Ottobah Cugoano

Thomas Clarkson and Ottobah Cugoano

Bite Size Advice 2

Bite Size Advice 2

Obligations in Roman Law

Obligations in Roman Law

Stocker and Dehner's Pediatric Pathology

Stocker and Dehner's Pediatric Pathology

Retouching Stalin's Moustache

Retouching Stalin's Moustache

Climate Change

Climate Change

Canadian Geography

Canadian Geography

Advanced Therapy in Facial Plastic and Reconstructive Surgery

Advanced Therapy in Facial Plastic and Reconstructive Surgery

General Thoracic Surgery

General Thoracic Surgery

Medicinal Chemistry

Medicinal Chemistry

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