Thomas Leu's Books

Proteins

Structures and Molecular Properties

By: Thomas E. Creighton

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Proteins

Structures and Molecular Properties

By: Thomas E. Creighton

Organized on a combined basis of chronology and of structural and functional hierarchy, This comprehensive text describes all aspects of proteins--biosynthesis, evolution, dynamics, ligand binding, catalysis, and energy transduction--not just their structures. This edition (first was 1984) is thoroughly updated--especially in the area of protein biosynthesis--and features end-of-chapter exercises and problems, many of which require the student to consult the cited literature in order to obtain the answer. Annotation copyright by Book News, Inc., Portland, OR

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534

Publisher

Macmillan

Published Date

ISBN 10

071677030X

ISBN 13

9780716770305

Wills' Biochemical Basis of Medicine

By: J. Hywel Thomas,Brian Gillham

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Wills' Biochemical Basis of Medicine

By: J. Hywel Thomas,Brian Gillham

Wills' Biochemical Basis of Medicine, Second Edition provides a basic understanding of the structure and metabolic processes in the context in which they occur in the cell or in the tissues. This book provides groundwork of academic biochemistry and demonstrations of the application of biochemistry to medicine. Organized into five parts encompassing 43 chapters, this edition begins with an overview of the biochemistry of the subcellular organelles. This text then examines the functions of the nucleus, mitochondria, and the endoplasmic reticulum. Other chapters consider the biochemistry of the hormones and the regulation of the metabolic fuels. This book discusses as well the biochemistry of environmental hazards and examines the treatment of viral carcinogenesis. The final chapter deals with the results of the application of recombinant DNA technology to the diagnosis of genetic disorder. This book is a valuable resource for biochemists, biologists, physicians, clinical researchers, and medical students.

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615

Publisher

Elsevier

Published Date

ISBN 10

1483183602

ISBN 13

9781483183602

Teaching the Language Arts

Forward Thinking in Today's Classrooms

By: Denise Johnson,Elizabeth Dobler,Thomas DeVere Wolsey

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Teaching the Language Arts

Forward Thinking in Today's Classrooms

By: Denise Johnson,Elizabeth Dobler,Thomas DeVere Wolsey

Teaching the Language Arts helps readers envision their future classrooms, including the role technology will play, as they prepare to be effective teachers. The book’s multimedia digital format represents a distinctive way to learn about teaching—combining traditional and electronic content, resources, and pedagogy to create a powerful, interactive experience that encourages active learning. Readers can explore a rich array of teaching tools and experiences, including an effective blend of classroom photographs (taken by the authors during school visits), student samples, podcast interviews with teachers and students, classroom videos, and online resources—all of which allow readers to learn from real-world classrooms. This book’s unique and engaging voice, supported by its multimedia approach, will help future and in-service teachers bring the language arts to life in their own classrooms. Visit the Companion Website at www.routledge.com/cw/dobler for information on accessing the interactive e-book and additional ideas and resources to help you and your students use it to its full potential.

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845

Publisher

Routledge

Published Date

ISBN 10

135166705X

ISBN 13

9781351667050

Monoclonal Antibodies

Cytokines and Arthritis, Mediators of Inflammation and Therapy

By: Kresina

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Monoclonal Antibodies

Cytokines and Arthritis, Mediators of Inflammation and Therapy

By: Kresina

Presents a sampling of new and novel approaches to the amelioration of musculoskeletal disease pathology, emphasizing prevention and therapy. Where applicable, these new technologies are focused on their application to human autoimmune diseases, but the volume mainly discusses and details the use of

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536

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CRC Press

Published Date

ISBN 10

1000104206

ISBN 13

9781000104202

Historic Whitefish Bay: A Celebration of Architecture and Character

By: Jefferson J. Aikin and Thomas H. Fehring

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Historic Whitefish Bay: A Celebration of Architecture and Character

By: Jefferson J. Aikin and Thomas H. Fehring

Incorporated in 1892, Whitefish Bay is a pleasant, verdant village that is home to more than fourteen thousand people. More than half of its five thousand houses and other structures have been deemed historic or architecturally important. Even casual passersby can attest to the architectural significance of these buildings, and while the personal history attached to them is less apparent, it is no less dramatic. Their walls retain the stories of their remarkable inhabitants, from the outhouse where the first village president disappeared in 1899 with $20,000 in public funds to the lakeside Beaux-Arts mansion built by a Schlitz Brewing Company heir with eight varieties of Italian marble. Jefferson J. Aikin and Thomas H. Fehring examine these landmark treasures and the legacy of the residents they help preserve.

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240

Publisher

Arcadia Publishing

Published Date

ISBN 10

1467137596

ISBN 13

9781467137591

Biochemistry and Physiology of Plant Hormones

By: Thomas C. Moore

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Biochemistry and Physiology of Plant Hormones

By: Thomas C. Moore

Biochemistry and Physiology oj Plant Hormones is intended primarily as a textbook or major reference for a one-term intermediate-level or advanced course dealing with hormonal regulation of growth and development of seed plants for students majoring in biology, botany, and applied botany fields such as agronomy, forestry, and horticulture. Additionally, it should be useful to others who wish to become familiar with the topic in relation to their principal student or professional interests in related fields. It is assumed that readers will have a background in fundamental biology, plant physiology, and biochemistry. The dominant objective of Biochemistry and Physiology oj Plant Hor mones is to summarize, in a reasonably balanced and comprehensive way, the current state of our fundamental knowledge regarding the major kinds of hormones and the phytochrome pigment system. Written primarily for students rather than researchers, the book is purposely brief. Biochemical aspects have been given priority intentionally, somewhat at the expense of physiological considerations. There are extensive citations of the literature-both old and recent-but, it is hoped, not so much documentation as to make the book difficult to read. The specific choices of publications to cite and illustrations to present were made for different reasons, often to illustrate historical develop ment, sometimes to illustrate ideas that later proved invalid, occasionally to exemplify conflicting hypotheses, and most often to illustrate the current state of our knowledge about hormonal phenomena.

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343

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1461236541

ISBN 13

9781461236542

Chemical Product Design and Formulation

Methods, Techniques, and Case Studies

By: Ali Elkamel,Hesham Alhumade,Navid Omidbakhsh,Keyvan Nowruzi,Thomas Duever

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Chemical Product Design and Formulation

Methods, Techniques, and Case Studies

By: Ali Elkamel,Hesham Alhumade,Navid Omidbakhsh,Keyvan Nowruzi,Thomas Duever

Chemical Product Formulation Design and Optimization Explore the cutting-edge in chemical product formulation and design In Chemical Product Formulation Design and Optimization: Methods, Techniques, and Case Studies, a team of renowned technologists and engineers delivers a practice guide to chemical product design. Offering real-world case studies for disinfectant formulation, the optimization of defined media, and the formulation of biocomposites, the book contains introduction to the current product design process. In addition to the background of related statistical techniques, readers will find: Clear illustrations, figures, and tables that improve understanding and retention of critical topics Thorough introductions to the mathematical principles of chemical product design A complete examination of intellectual property considerations in the chemical product design process Ideal for process and chemical engineers, Chemical Product Formulation Design and Optimization: Methods, Techniques, and Case Studies is a must-read resource for professionals in the pharmaceutical and cosmetics industry as well as chemical engineers working in the food, paint, and dye industries who seek a one-stop resource that includes the latest advances in chemical product formulation.

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229

Publisher

John Wiley & Sons

Published Date

ISBN 10

3527332642

ISBN 13

9783527332649

Thrive in Genetics

By: Alison Thomas

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Thrive in Genetics

By: Alison Thomas

The Thrive in Bioscience revision guides are written to help undergraduate students achieve exam success in all core areas of bioscience. They communicate all the key concepts in a succinct, easy-to-digest way, using features and tools - both in the book and in digital form - to make learning even more effective.

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340

Publisher

Oxford University Press

Published Date

ISBN 10

0199694621

ISBN 13

9780199694624

Alligator Metabolism Studies on Chemical Reactions in Vivo

By: Roland A. Coulson,Thomas Hernandez

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Alligator Metabolism Studies on Chemical Reactions in Vivo

By: Roland A. Coulson,Thomas Hernandez

Alligator Metabolism: Studies on Chemical Reactions in Vivo presents a summary of research in vivo on the metabolism of alligators. The volume contains updates of earlier investigations which were presented in Biochemistry of the Alligator, a Study of Metabolism in Slow Motion (1964). Since then, with the aid of better equipment and better methods, it seemed time to correlate and summarize the findings of researchers who have used this remarkable experimental animal with profit. The primary purpose of almost all the research was not to determine the nature of the alligator, but to understand biochemical reactions in vivo and the alligator was a means to that end. The book begins with a chapter on natural history for those scientists, wild-life experts, alligator farmers, zoo keepers etc., whose primary interest is in the nature and habits of the intact alligator. This is followed by separate chapters that deal with metabolic rate, anaerobic glycolysis, digestion-growth-protein synthesis, carbohydrate metabolism, amino acid metabolism, respiration and acid-base balance, and kidney function.

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191

Publisher

Elsevier

Published Date

ISBN 10

1483161552

ISBN 13

9781483161556

Body Symbolism in the Bible

By: Silvia Schroer,Thomas Staubli

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Body Symbolism in the Bible

By: Silvia Schroer,Thomas Staubli

Many people with illnesses seek healing in religions and practices that are only weakly inculturated among us. Our understanding and use of such foreign wisdom is often just as superficial; but it is easily understood against the background of a centuries-long Christian tradition of interpreting the Bible in a way hostile to the body, particularly the female body. In Body Symbolism in the Bible, Schroer and Staubli offer a better understanding of this subject by exploring the symbolism of various body parts in the Bible. They reinterpret and thereby reclaim the notion of the body as a temple of God so that regard for the body can lead to respect for the human rights of women and men. Exploring the topic through the lenses of theological anthropology and biblical spirituality, their presentation will surely add clarity to our understanding and generate future discussion. Richly illustrated in full color.

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270

Publisher

Liturgical Press

Published Date

ISBN 10

0814687792

ISBN 13

9780814687796

Fundamentals of Medicinal Chemistry

By: Gareth Thomas

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Fundamentals of Medicinal Chemistry

By: Gareth Thomas

Provides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style. The title begins by reviewing the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms. An overview of medicinal chemistry is followed by chapters covering the discovery and design of drugs, pharmacokinetics and drug metabolism, The book concludes with a chapter on organic synthesis, followed by a brief look at drug development from the research stage through to marketing the final product. The text assumes little in the way of prior biological knowledge. relevant biology is included through biological topics, examples and the Appendices. Incorporates summary sections, examples, applications and problems Each chapter contains an additional summary section and solutions to the questions are provided at the end of the text Invaluable for undergraduates studying within the chemical, pharmaceutical and life sciences.

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302

Publisher

John Wiley & Sons

Published Date

ISBN 10

0470871695

ISBN 13

9780470871690

Introduction to Organic Chemistry

By: William H. Brown,Thomas Poon

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Introduction to Organic Chemistry

By: William H. Brown,Thomas Poon

Introduction to Organic Chemistry, 6th Edition provides an introduction to organic chemistry for students who require the fundamentals of organic chemistry as a requirement for their major. It is most suited for a one semester organic chemistry course. In an attempt to highlight the relevance of the material to students, the authors place a strong emphasis on showing the interrelationship between organic chemistry and other areas of science, particularly the biological and health sciences. The text illustrates the use of organic chemistry as a tool in these sciences; it also stresses the organic compounds, both natural and synthetic, that surround us in everyday life: in pharmaceuticals, plastics, fibers, agrochemicals, surface coatings, toiletry preparations and cosmetics, food additives, adhesives, and elastomers. This text is an unbound, three hole punched version. Access to WileyPLUS sold separately.

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723

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119106966

ISBN 13

9781119106968

Environmental Issues in Chemical Perspective

By: Thomas G. Spiro,William M. Stigliani

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Environmental Issues in Chemical Perspective

By: Thomas G. Spiro,William M. Stigliani

An in-depth presentation of the chemistry required to evaluate the choices we must make regarding our environment, this study has four parts: energy, the atmosphere, the hydrosphere, and the biosphere. Each part is followed by problem sets that require the application of chemical principles to such issues as dwindling natural gas and petroleum resources; fission and fusion as energy sources; CO2 build-up and the greenhouse effect; automobile emission control; acid rain; eutrophication of lakes; lead, mercury, and cadmium poisoning; and environmental links to cancer. An answer manual for the problems is included. Social, political, and economic concerns are also covered. The authors show how chemists and non-chemist decision-makers can take account of each other's perspectives.

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Page Count

390

Publisher

SUNY Press

Published Date

ISBN 10

0873954270

ISBN 13

9780873954273

Quantitative Understanding of Biosystems

An Introduction to Biophysics

By: Thomas M. Nordlund,Peter M. Hoffmann

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Quantitative Understanding of Biosystems

An Introduction to Biophysics

By: Thomas M. Nordlund,Peter M. Hoffmann

Quantitative Understanding of Biosystems: An Introduction to Biophysics focuses on the behavior and properties of microscopic structures that underlie living systems. It clearly describes the biological physics of macromolecules, subcellular structures, and whole cells, including interactions with light.Providing broad coverage of physics, chemistr

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578

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CRC Press

Published Date

ISBN 10

1439891133

ISBN 13

9781439891131

The Best Test Preparation for the SAT, Subject Test

With CD-ROM for Windows. Biology E/M

By: Linda Gregory,Thomas Sandusky,Rashmi Diana Sharma,Judith A. Stone

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The Best Test Preparation for the SAT, Subject Test

With CD-ROM for Windows. Biology E/M

By: Linda Gregory,Thomas Sandusky,Rashmi Diana Sharma,Judith A. Stone

Taking the Biology E/M SAT Subject Test™? Score Higher with REA's Test Prep for the SAT Subject Test™: Biology E/M with Practice Tests on CD Our bestselling SAT Subject Test™: Biology E/M test prep includes a comprehensive review of the chemistry of life, cells, genetics, biodiversity, classification, and more. Each chapter contains examples and practice questions that help you study smarter and boost your test score. The book includes 6 full-length practice tests that replicate the exam's question format. Two of the book's practice exams are offered on our TestWare CD with the most powerful scoring and diagnostic tools available today. Automatic scoring and instant reports help you zero in on the topics and types of questions that give you trouble now, so you'll succeed when it counts. Each practice test comes with detailed explanations of answers to identify your strengths and weaknesses. We don't just say which answers are right - we also explain why the other answer choices are incorrect - so you'll be prepared. The book also includes study tips, strategies, and confidence-boosting advice you need for test day. This test prep is a must for any high school student taking the SAT Subject Test™: Biology E/M!

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530

Publisher

Research & Education Assoc.

Published Date

ISBN 10

0738601217

ISBN 13

9780738601212

Nutrition for Sport, Exercise, and Health

By: Marie Spano,Laura Kruskall,D. Travis Thomas

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Nutrition for Sport, Exercise, and Health

By: Marie Spano,Laura Kruskall,D. Travis Thomas

Nutrition for Sport, Exercise, and Health, Second Edition With HKPropel Access, blends applied content with updated research-based guidelines to help students distinguish between nutrition recommendations backed by science and the plethora of misinformation available. Covering all the basics of nutrition, students will walk away with a clear understanding of how nutrition affects sport, exercise, and overall health. Organized to facilitate knowledge retention, the text logically progresses, with each chapter building upon the information previously presented. Students first get an overview of the role nutrition plays in overall well-being throughout a person’s life. They will learn the functions of carbohydrates, fat, and protein as well as the role each of these macronutrients plays in health and disease. And they will learn the dietary recommendations that support health and an active lifestyle. Next, the function of micronutrients in health and performance is covered. The text concludes with the application of nutrition principles, with guidance to properly fuel for sport, exercise, and health. Updated based on Dietary Guidelines for Americans, 2020-2025, the second edition incorporates new content on the following: The effect of ketogenic diets on health and muscle Vitamin D and its role in performance and inflammation The effect of progressive training programs on metabolism Sample nutrition plans, including a daily fluid plan, a plan to meet mineral needs, a food plan for resistance training, and more Omega-3 supplementation to support concussion prevention and recovery The latest research on why people regain weight after weight loss To assist students using the text, the second edition of Nutrition for Sport, Exercise, and Health has related online learning tools delivered through HKPropel to help students understand and apply concepts and research findings. These learning tools include flash cards to review key terms presented in the book and supplemental chapter activities to assess student learning and facilitate critical thinking. The chapter activities may be assigned and tracked by instructors through HKPropel, and chapter quizzes that are automatically graded can be used to test comprehension of critical concepts. Pedagogical aids within the text also enhance student understanding; these include chapter objectives, key terms, and review questions. Numerous sidebars provide key insights, real-world tips, relatable scenarios, and easy takeaways. Students and professionals alike will benefit from the broad coverage found in Nutrition for Sport, Exercise, and Health. They will have the science-based knowledge and tools they need to improve athletic performance, exercise outcomes, and general well-being. Note: A code for accessing HKPropel is not included with this ebook but may be purchased separately.

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482

Publisher

Human Kinetics

Published Date

ISBN 10

1718207794

ISBN 13

9781718207790

Preparation of Compounds Labeled with Tritium and Carbon-14

By: Rolf Voges,J. Richard Heys,Thomas Moenius

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Preparation of Compounds Labeled with Tritium and Carbon-14

By: Rolf Voges,J. Richard Heys,Thomas Moenius

Compounds labeled with carbon-14 and tritium are indispensable tools for research in biomedical sciences, discovery and development of pharmaceuticals and agrochemicals. Preparation of Compounds Labeled with Tritium and Carbon-14 is a comprehensive, authoritative and up-to-date discussion of the strategies, synthetic approaches, reactions techniques, and resources for the preparation of compounds labeled with either of these isotopes. A large number of examples are presented for the use of isotopic sources and building blocks in the preparation of labeled target compounds, illustrating the range of possibilities for embedding isotopic labels in selected moieties of complex structures. Topics include: Formulation of synthetic strategies for preparing labeled compounds Isotope exchange methods and synthetic alternatives for preparing tritiated compounds In-depth discussion of carbon-14 building blocks and their utility in synthesis Preparation of enantiomerically pure isotopically labeled compounds Applications of biotransformations Preparation of Compounds Labeled with Tritium and Carbon-14 is an essential guide to the specialist strategies and tactics used by chemists to prepare compounds tagged with theradioactive atoms carbon-14 and tritium.

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Page Count

682

Publisher

John Wiley & Sons

Published Date

ISBN 10

0470743433

ISBN 13

9780470743430

Architects of Structural Biology

Bragg, Perutz, Kendrew, Hodgkin

By: John Meurig Thomas

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Architects of Structural Biology

Bragg, Perutz, Kendrew, Hodgkin

By: John Meurig Thomas

Architects of Structural Biology is an amalgam of memoirs, biography, and intellectual history of the personalities and single-minded devotion of four scientists who are among the greatest in modern times. These three chemists and one physicist, all Nobel laureates, played a pivotal role in the creation of a new and pervasive branch of biology. This led in turn to major developments in medicine and to the treatment of diseases as a result of advances made in arguably one of the greatest centres of scientific research ever: the Laboratory of Molecular Biology in Cambridge, which they helped to establish. Their work and that of their predecessors at the Royal Institution in London reflects the broader cultural, scientific and educational strength of the UK from the early 19th century onwards. The book also illustrates the nurturing of academic life in the collegiate system, exemplified by the activities of, and cross-fertilization within, a small Cambridge college.

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Page Count

320

Publisher

Oxford University Press

Published Date

ISBN 10

0192596713

ISBN 13

9780192596710

Medicinal Chemistry

An Introduction

By: Gareth Thomas

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Medicinal Chemistry

An Introduction

By: Gareth Thomas

Medicinal Chemistry: An Introduction, Second Edition provides a comprehensive, balanced introduction to this evolving and multidisciplinary area of research. Building on the success of the First Edition, this edition has been completely revised and updated to include the latest developments in the field. Written in an accessible style, Medicinal Chemistry: An Introduction, Second Edition carefully explains fundamental principles, assuming little in the way of prior knowledge. The book focuses on the chemical principles used for drug discovery and design covering physiology and biology where relevant. It opens with a broad overview of the subject with subsequent chapters examining topics in greater depth. From the reviews of the First Edition: "It contains a wealth of information in a compact form" ANGEWANDTE CHEMIE, INTERNATIONAL EDITION "Medicinal Chemistry is certainly a text I would chose to teach from for undergraduates. It fills a unique niche in the market place." PHYSICAL SCIENCES AND EDUCATIONAL REVIEWS

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Page Count

660

Publisher

John Wiley & Sons

Published Date

ISBN 10

111996542X

ISBN 13

9781119965428

Brown's Introduction to Organic Chemistry

By: William H. Brown,Thomas Poon

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Brown's Introduction to Organic Chemistry

By: William H. Brown,Thomas Poon

Introduction to Organic Chemistry, 6th Global Edition provides an introduction to organic chemistry for students who require the fundamentals of organic chemistry as a requirement for their major. It is most suited for a one semester organic chemistry course. In an attempt to highlight the relevance of the material to students, the authors place a strong emphasis on showing the interrelationship between organic chemistry and other areas of science, particularly the biological and health sciences. The text illustrates the use of organic chemistry as a tool in these sciences; it also stresses the organic compounds, both natural and synthetic, that surround us in everyday life: in pharmaceuticals, plastics, fibers, agrochemicals, surface coatings, toiletry preparations and cosmetics, food additives, adhesives, and elastomers.

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724

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119382882

ISBN 13

9781119382881

Nathan and Oski's Hematology and Oncology of Infancy and Childhood E-Book

By: Stuart H. Orkin,David G. Nathan,David Ginsburg,A. Thomas Look,David E. Fisher,Samuel Lux

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Nathan and Oski's Hematology and Oncology of Infancy and Childhood E-Book

By: Stuart H. Orkin,David G. Nathan,David Ginsburg,A. Thomas Look,David E. Fisher,Samuel Lux

Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. - Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. - Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. - Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. - Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. - Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. - Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. - Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.

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3517

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323291775

ISBN 13

9780323291774

Evolutionary Algorithms in Theory and Practice

Evolution Strategies, Evolutionary Programming, Genetic Algorithms

By: Thomas Bäck

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Evolutionary Algorithms in Theory and Practice

Evolution Strategies, Evolutionary Programming, Genetic Algorithms

By: Thomas Bäck

A comparison of evolutionary algorithms. Organic evolution and problem solving. Biological background. Evolutionary algorithms and artificial intelligence. Evolutionary algorithms and global optimization. Early approaches. Specific evolutionary algorithms. Evolution strategies. Evolutionary programming. Genetic algorithms. Artificial landscapes. An empirical comparison. Extending genetic algorithms. Selection. Selection mechanisms. Experimental investigation of selection. Mutation. Simplified genetic algorithms. An experiment in meta-evolution. Summary and outlook. Data for the fletcher-powell function. Data from selection experiments. Software. The multiprocessor environment; mathematical symbols.

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329

Publisher

Oxford University Press, USA

Published Date

ISBN 10

0195099710

ISBN 13

9780195099713

Neurovascular Immunology

Vasoactive Neurotransmitters and Modulators in Cellular Immunity and Memory

By: Thomas C. Moore

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Neurovascular Immunology

Vasoactive Neurotransmitters and Modulators in Cellular Immunity and Memory

By: Thomas C. Moore

Neurovascular Immunology provides an in-depth exploration of the neurovascular branch of the neuro-immune axis. The book includes discussions regarding the role of neurovascular molecules and their evolutionary history in biological defense, their major functions in invertebrates, their roles in terrestrial vertebrates, and their involvement in the organization and function of the vascular and nervous systems, including the immune response defense system. The book will appeal to all researchers, practitioners, and students interested in the functions of the nervous, vascular, and immune response systems.

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Page Count

478

Publisher

CRC Press

Published Date

ISBN 10

0849368944

ISBN 13

9780849368943

Computers and DNA

By: Thomas Marr

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Computers and DNA

By: Thomas Marr

The fields of molecular biology and genetics are faced with an enormous accumulation of information: DNA sequencing, associated sequences of amino acids in proteins, genetics, macromolecular structures and other sets have created a quantitative backlog of data which needs to be organized and analyzed. Moreover, the rate of data acquisitions is accelerating as improved technologies are used and as organized programs such as the Human Genome Initiative are established. Because of this data's importance, molecular biologists have turned to computational scientists for help in processing this mass of information.The Santa Fe Institute organized a workshop on "The Interface Between Computational Science and DNA Sequencing" in 1998 to address this information crisis. Approximately one hundred molecular biologists, computer scientists, mathematicians, and other scientists in diverse fields met to discuss how computational science can best keep pace with molecular biology. The papers presented at that meeting and included in this volume serve as a comprehensive introduction to the field and as a discussion of research on some of the current problems.

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296

Publisher

Routledge

Published Date

ISBN 10

0429970013

ISBN 13

9780429970016

Statistical Methods in Genetic Epidemiology

By: Duncan C. Thomas

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Statistical Methods in Genetic Epidemiology

By: Duncan C. Thomas

This well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on disease patterns. It follows the natural sequence of research, taking readers through the study designs and statistical analysis techniques for determining whether a trait runs in families, testing hypotheses about whether a familial tendency is due to genetic or environmental factors or both, estimating the parameters of a genetic model, localizing and ultimately isolating the responsible genes, and finally characterizing their effects in the population. Examples from the literature on the genetic epidemiology of breast and colorectal cancer, among other diseases, illustrate this process. Although the book is oriented primarily towards graduate students in epidemiology, biostatistics and human genetics, it will also serve as a comprehensive reference work for researchers. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics will help make the book accessible to those coming from one of these fields without a background in the others. It strikes a good balance between epidemiologic study designs and statistical methods of data analysis.

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Page Count

458

Publisher

Oxford University Press

Published Date

ISBN 10

0199748055

ISBN 13

9780199748051

Foye's Principles of Medicinal Chemistry

By: Victoria Roche,William S. Zito,Thomas Lemke,David A. Williams

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Foye's Principles of Medicinal Chemistry

By: Victoria Roche,William S. Zito,Thomas Lemke,David A. Williams

With expert contributions from experienced educators, research scientists and clinicians, Foye’s Principles of Medicinal Chemistry, Eighth Edition is an invaluable resource for professional students, graduate students and pharmacy faculty alike. This ‘gold standard’ text explains the chemical basis of drug action, emphasizing the structure-activity relationships, physicochemical-pharmacokinetic properties, and metabolic profiles of the most commonly used drugs.

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Page Count

6058

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

149638587X

ISBN 13

9781496385871

Nuclear magnetic Resonance in biochemistry

By: Thomas James

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Nuclear magnetic Resonance in biochemistry

By: Thomas James

Nuclear Magnetic Resonance in Biochemistry: Principles and Applications focuses on the principles and applications of nuclear magnetic resonance (NMR) in biochemistry. Topics covered include experimental methods in NMR; the mechanisms of NMR relaxation; chemical and paramagnetic shifts; spin-spin splitting; the use of NMR in investigations of biopolymers and biomolecular interactions; and molecular dynamics in biological and biochemical systems. This text is comprised of eight chapters; the first of which gives an overview of NMR spectroscopy and its use in studies of biological systems. The next two chapters discuss the theoretical basis for NMR applications in biochemistry, with emphasis on Bloch equations, quantum mechanics, correlation function and correlation time, double resonance, and chemical exchange. The reader is then introduced to the basis for chemical shifts and spin-spin splitting, along with several examples of the use of these NMR parameters in studies of small molecule interactions and structure. The experimental apparatus and procedures employed in NMR studies, Fourier transform NMR, and NMR spectral parameters of small molecules interacting with macromolecules are also considered. The book highlights the information obtainable from the spectra of biopolymers, and then concludes with a chapter on NMR investigations of the state of motion of lipids in membranes and model membranes; water in macromolecular and cellular systems; and sodium ion in biological tissue. This book is intended primarily for chemists, biochemists, biophysicists, and molecular biologists, as well as graduate students.

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Page Count

428

Publisher

Elsevier

Published Date

ISBN 10

0323141048

ISBN 13

9780323141048

Book's by Thomas Leu

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