In this prize-winning book Thomas Holt is concerned not only with the identities of the black politicians who gained power in South Carolina during Reconstruction, but also with the question of how they functioned within the political system. Thus, as one reviewer has commented, "he penetrates the superficial preoccupations over whether black politicians were venal or gullible to see whether they wielded power and influence and, if they did, how and to what ends and against what obstacles." "Well crafted and well written, it not only broadens our knowledge of the period, but also deepens it, something that recent books on Reconstruction have too often failed to do." -- Michael Perman, American Historical Review. . . . a valuable study of post-Civil War black leaders in a state where Negro control came closest to realization during Reconstruction. . . . Effectively merging the techniques of quantitative analysis with those of narrative history, Holt shatters a number of myths and misconceptions. . . . It should be on the reading list of all students of Reconstruction and nineteenth-century black history." -- William C. Harris, Journal of Southern History "Holt presents his work modestly as a state study of reconstruction politics. But this should not obscure a significant intellectual achievement and a contribution of fundamental importance, demonstrating the value of social-class analysis in understanding the politics of the black community." -- Jonathan M. Wiener, Journal of American History.
An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. - Provides an introduction to the properties of transport proteins: channels, carriers, and pumps - Presents up-to-date information on the structure of transport proteins and on their function and regulation - Includes introductions to transport kinetics and to the cloning of genes that code transport proteins - Furnishes a link between the experimental basis of the subject and theoretical model building
In this book, Thomas F. Tartaron presents a new and original reassessment of the maritime world of the Mycenaean Greeks of the Late Bronze Age. By all accounts a seafaring people, they enjoyed maritime connections with peoples as distant as Egypt and Sicily. These long-distance relations have been celebrated and much studied; by contrast, the vibrant worlds of local maritime interaction and exploitation of the sea have been virtually ignored. Dr Tartaron argues that local maritime networks, in the form of 'coastscapes' and 'small worlds', are far more representative of the true fabric of Mycenaean life. He offers a complete template of conceptual and methodological tools for recovering small worlds and the communities that inhabited them. Combining archaeological, geoarchaeological and anthropological approaches with ancient texts and network theory, he demonstrates the application of this scheme in several case studies. This book presents new perspectives and challenges for all archaeologists with interests in maritime connectivity.
In 1636, Roger Williams, recently banished from the Massachusetts Bay Colony because of his religious beliefs, established a settlement at the head of Narragansett Bay that he named “Providence.” This small colony soon became a sanctuary for those seeking to escape religious persecution. Within a few years, a royal land patent and charter resulted in the formation of the “Colony of Rhode Island and Providence Plantations,” which incorporated Williams’ original settlement and espoused his tenets of freedom of religion and separation of church and state. During the ensuing decades, thousands of Baptists, Quakers, Jews, and Huguenots relocated to Rhode Island from other New England colonies, the British Islands, and Europe in search of religious freedom. One such individual, John Thomas, an immigrant from Wales, made significant contributions to early settlements at Jamestown on Conanicut Island and at Wickford on the nearby mainland of Rhode Island. He was the first town constable of Jamestown in 1679, and later owned hundreds of acres of land in the towns of North and South Kingstown. This fully indexed work traces and sketches the lives of his descendants, many of whom were at the forefront of the great American westward migration, and represents the most comprehensive compilation of them to date. It is the result of twenty years of extensive research and includes detailed information from military pension archives, will and estate records, agricultural data, county histories, and migration patterns that far exceeds the standard for genealogical works of this scope and magnitude. It is important for us to remember those who helped shape our nation. This work provides valuable information for those who are interested in this family and its evolution in America.
This timely reference presents, for the first time, new findings in molecular genetics that are applicable to the epidemiology, pathogenesis, neuropathology, clinical features, and management of ataxia-bridging the gap between scientific and clinical practice. Organized by the distinctive ataxia disorders, their pathogenesis, and management-facilitating quick and efficient diagnoses! Providing complementary sections on the anatomy of the spinocerebellar system, its normal function, and a history of ataxia research and management, the Handbook of Ataxia Disorders clarifies the impact of identifying the molecular causes of ataxia offers in-depth analysis of dominant and recessive and nonhereditary ataxia disorders explores the vital connection between the genotypes and phenotypes of various degenerative ataxia disorders and more! Written by more than 60 international experts and supplemented with over 2600 literature references, photographs, micrographs, drawings, and tables, the Handbook of Ataxia Disorders is an essential and useful reference for clinical neurologists and neuropathologists, neuropediatricians, geneticists, physiatrists, and medical school students in these disciplines.
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