Thomas J. Saunders's Books

Medicinal Chemistry

A Molecular and Biochemical Approach

By: Thomas Nogrady,Donald F. Weaver

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Medicinal Chemistry

A Molecular and Biochemical Approach

By: Thomas Nogrady,Donald F. Weaver

Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.

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664

Publisher

Oxford University Press

Published Date

ISBN 10

0198026455

ISBN 13

9780198026457

Mammals of Africa

By: Jonathan Kingdon,David Happold,Thomas Butynski,Michael Hoffmann,Meredith Happold,Jan Kalina

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Mammals of Africa

By: Jonathan Kingdon,David Happold,Thomas Butynski,Michael Hoffmann,Meredith Happold,Jan Kalina

Mammals of Africa (MoA) is a series of six volumes which describes, in detail, every currently recognized species of African land mammal. This is the first time that such extensive coverage has ever been attempted, and the volumes incorporate the very latest information and detailed discussion of the morphology, distribution, biology and evolution (including reference to fossil and molecular data) of Africa's mammals. With 1,160 species and 16 orders, Africa has the greatest diversity and abundance of mammals in the world. The reasons for this and the mechanisms behind their evolution are given special attention in the series. Each volume follows the same format, with detailed profiles of every species and higher taxa. The series includes some 660 colour illustrations by Jonathan Kingdon and his many drawings highlight details of morphology and behaviour of the species concerned. Diagrams, schematic details and line drawings of skulls and jaws are by Jonathan Kingdon and Meredith Happold. Every species also includes a detailed distribution map. Extensive references alert readers to more detailed information. Volume I: Introductory Chapters and Afrotheria (352 pages) Volume II: Primates (560 pages) Volume III: Rodents, Hares and Rabbits (784 pages) Volume IV: Hedgehogs, Shrews and Bats (800 pages) Volume V: Carnivores, Pangolins, Equids and Rhinoceroses (560 pages) Volume VI: Pigs, Hippopotamuses, Chevrotain, Giraffes, Deer and Bovids (704 pages)

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Page Count

3500

Publisher

A&C Black

Published Date

ISBN 10

1408189968

ISBN 13

9781408189962

Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice

By: Charles J. Lockwood,Thomas Moore,Joshua Copel,Robert M Silver,Robert Resnik

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Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice

By: Charles J. Lockwood,Thomas Moore,Joshua Copel,Robert M Silver,Robert Resnik

Long recognized as the authoritative leader in the field, Creasy and Resnik's Maternal-Fetal Medicine, 8th Edition, continues to provide the latest evidence-based guidelines for obstetric and neonatal management, helping you minimize complications and offer patients the best possible care. Written by renowned experts in obstetrics, gynecology, and perinatology, this comprehensive resource has been thoroughly updated and reflects new information in every area, including recent tremendous advances in genetics, imaging, and more. Focuses on complicated obstetric issues, highlighting the most commonly encountered anomalies and providing clear guidelines for obstetric and neonatal management. Offers comprehensive updates on rapidly changing topics, including a completely revised section on genetics and genetic technology for prenatal diagnoses, as well as an expanded imaging section on abdominal, urogenital, and skeletal imaging. Includes four new chapters: Molecular Genetic Technology, MRI in Obstetrical Imaging, Obesity in Pregnancy, and Pregnancy as a Window to Future Health. Features numerous flow charts for quick access to diagnosis and treatment protocols and to clarify complex material. Presents the knowledge and expertise of new editors Dr. Joshua Copel, an expert in the field of fetal therapy who has pioneered new diagnostic techniques for unborn patients and their mothers, and Dr. Robert Silver, a leader in the maternal-fetal medicine community.

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1859

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323568912

ISBN 13

9780323568913

Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice E-Book

Expert Consult Premium Edition - Enhanced Online Features

By: Robert K. Creasy,Robert Resnik,Jay D. Iams,Charles J. Lockwood,Thomas Moore,Michael F Greene

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Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice E-Book

Expert Consult Premium Edition - Enhanced Online Features

By: Robert K. Creasy,Robert Resnik,Jay D. Iams,Charles J. Lockwood,Thomas Moore,Michael F Greene

Minimize complications with Creasy and Resnik's Maternal-Fetal Medicine. This medical reference book puts the most recent advances in basic science, clinical diagnosis, and management at your fingertips, equipping you with the up-to date evidence-based guidelines and knowledge you need to ensure the best possible outcomes in maternal-fetal medicine. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Apply today’s best practices in maternal-fetal medicine with an increased emphasis on evidence-based medicine. Find dependable, state-of-the-art answers to any clinical question with comprehensive coverage of maternal-fetal medicine from the foremost researchers and practitioners in obstetrics, gynecology and perinatology. Take advantage of the most recent diagnostic advances with a new section on Obstetrical Imaging, complemented by online ultrasound clips as well as cross references and links to genetic disorder databases. Stay on top of rapidly evolving maternal-fetal medicine through new chapters on Recurrent Spontaneous Abortion, Stillbirth, Patient Safety, Maternal Mortality, and Substance Abuse, as well as comprehensive updates on the biology of parturition, fetal DNA testing from maternal blood, fetal growth, prenatal genetic screening and diagnosis, fetal cardiac malformations and arrhythmias, thyroid disease and pregnancy, management of depression and psychoses during pregnancy and the puerperium, and much more. Access the complete contents online at Expert Consult.

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Page Count

1649

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323186653

ISBN 13

9780323186650

Master Techniques in Orthopaedic Surgery: The Hand

By: Steven Maschke,Thomas J. Graham,Peter Evans

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Master Techniques in Orthopaedic Surgery: The Hand

By: Steven Maschke,Thomas J. Graham,Peter Evans

Master the orthopaedic techniques preferred by today’s expert surgeons! The 3rd Edition of this highly regarded title remains your go-to resource for the most advanced and effective surgical techniques for treating traumatic, congenital, inflammatory, neoplastic, and degenerative conditions of the hand. More than 1,000 high-quality photographs and drawings guide you step by step through each procedure, and personal pearls from master surgeons provide operative tips that foster optimal outcomes. 13 new chapters bring you completely up to date with what’s new in the field.

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Page Count

1282

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1496330056

ISBN 13

9781496330055

Credit Scoring and Its Applications

By: Lyn C. Thomas,David B. Edelman,Jonathan N. Crook

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Credit Scoring and Its Applications

By: Lyn C. Thomas,David B. Edelman,Jonathan N. Crook

The only book that details the mathematical models that help creditors make intelligent credit risk decisions.

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Page Count

256

Publisher

SIAM

Published Date

ISBN 10

0898714834

ISBN 13

9780898714838

The Fight of the Century

Jack Johnson, Joe Louis, and the Struggle for Racial Equality

By: Thomas R. Hietala

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The Fight of the Century

Jack Johnson, Joe Louis, and the Struggle for Racial Equality

By: Thomas R. Hietala

A revealing look at the history of race relations in the United States during the first half of the twentieth century portrayed through the lives and times of the first two African-American heavyweight boxing champions, Jack Johnson and Joe Louis. The author incorporates extensive research into the black press of the time, and explores how the public careers and private lives of these two sports figures both define and explain vital issues in U.S. history.

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Page Count

404

Publisher

M.E. Sharpe

Published Date

ISBN 10

0765607220

ISBN 13

9780765607225

Feeling Italian

The Art of Ethnicity in America

By: Thomas J. Ferraro

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Feeling Italian

The Art of Ethnicity in America

By: Thomas J. Ferraro

Southern Italian emigration to the United States peaked a full century ago, descendents are now fourth and fifth generation, dispersed from their old industrial neighborhoods, professionalized, and fully integrated into the melting pot. Surely the social historians are right: Italian Americans are fading into the twilight of their ethnicity. So, why is the American imagination enthralled by The Sopranos, and other portraits of Italian-ness?

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Page Count

273

Publisher

NYU Press

Published Date

ISBN 10

0814727476

ISBN 13

9780814727478

Commentary on Aristotle's Politics

By: Thomas Aquinas

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Commentary on Aristotle's Politics

By: Thomas Aquinas

Offering the first complete translation into modern English of Aquinas' unfinished commentary on Aristotle's Politics, this translation follows the definitive Leonine text of Aquinas and reproduces in English those passages of William of Moerbeke's exacting yet elliptical translation of the Politics from which Aquinas worked. Bekker numbers have been added to passages from the Politics for easy reference. Students of the history of political thought will welcome this study of a great classic, a commentary by a student of Aristotle who is also a great political theorist in his own right.

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225

Publisher

Hackett Publishing

Published Date

ISBN 10

1603840087

ISBN 13

9781603840088

Speaking Philosophically

Communication at the Limits of Discursive Reason

By: Thomas Sutherland

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Speaking Philosophically

Communication at the Limits of Discursive Reason

By: Thomas Sutherland

Western philosophy has often claimed for itself not just a distinct sphere of knowledge, but a distinct form of communication, set against ordinary speech. In Speaking Philosophically, Thomas Sutherland proposes that for some philosophers, authentic philosophizing demands a specific manner of speaking or writing, adoption of which enables one to gesture toward truths that propositional speech will never grasp. Drawing on a variety of thinkers – Heraclitus, Plato, Kant, Fichte, Nietzsche, Kierkegaard, Weil, Foucault, and Irigaray – Sutherland argues this emphasis on the form of philosophical communication can function as an exclusionary mechanism, determining who is deemed capable of speaking philosophically.

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157

Publisher

Bloomsbury Publishing

Published Date

ISBN 10

1350160849

ISBN 13

9781350160842

Hollywood in Berlin

American Cinema and Weimar Germany

By: Thomas J. Saunders

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Hollywood in Berlin

American Cinema and Weimar Germany

By: Thomas J. Saunders

The setting is 1920s Berlin, cultural heart of Europe and the era's only serious cinematic rival to Hollywood. In his engaging study, Thomas Saunders explores an outstanding example of one of the most important cultural developments of this century: global Americanization through the motion picture. The invasion of Germany by American films, which began in 1921 with overlapping waves of sensationalist serials, slapstick shorts, society pictures, and historical epics, initiated a decade of cultural collision and accommodation. On the one hand it fueled an impassioned debate about the properties of cinema and the specter of wholesale Americanization. On the other hand it spawned unprecedented levels of cooperation and exchange. In Berlin, American motion pictures not only entertained all social classes and film tastes but also served as a vehicle for American values and a source of sharp economic competition. Hollywood in Berlin correlates the changing forms of Hollywood's contributions to Weimar culture and the discourses that framed and interpreted them, restoring historical contours to a leading aspect of cultural interchange in this century. At the same time, the book successfully embeds Weimar cinema in its contemporary international setting.

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Page Count

416

Publisher

Univ of California Press

Published Date

ISBN 10

0520914163

ISBN 13

9780520914162

My Century in History

Memoirs

By: Thomas D. Clark

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My Century in History

Memoirs

By: Thomas D. Clark

When Thomas D. Clark was hired to teach history at the University of Kentucky in 1931, he began a career that would span nearly three-quarters of a century and would profoundly change not only the history department and the university but the entire Commonwealth. His still-definitive History of Kentucky (1937) was one of more than thirty books he would write or edit that dealt with Kentucky, the South, and the American frontier. In addition to his wide scholarly contributions, Clark devoted his life to the preservation of Kentucky's historical records. He began this crusade by collecting vast stores of Kentucky's military records from the War of 1812, the Mexican War, and the Civil War. His efforts resulted in the Commonwealth's first archival system and the subsequent creation of the Kentucky Library and Archives, the University of Kentucky Special Collections and Archives, the Kentucky Oral History Commission, the Kentucky History Center (recently named for him), and the University Press of Kentucky. Born in 1903 on a cotton farm in Louisville, Mississippi, Thomas Dionysius Clark would follow a long and winding path to find his life's passion in the study of history. He dropped out of school after seventh grade to work first at a sawmill and then on a canal dredgeboat before resuming his formal education. Clark's earliest memories—hearing about local lynch-mob violence and witnessing the destruction of virgin forest—are an invaluable window into the national issues of racial injustice and environmental depredation. In many ways, the story of Dr. Clark's life is the story of America in the twentieth century. In My Century in History, Clark offers vivid memories of his journey, both personal and academic, a journey that took him from Mississippi to Kentucky and North Carolina, to leadership of the nation's major historical organizations, and to visiting professorships in Austria, England, Greece, and India, as well as in universities throughout the United States. An enormously popular public lecturer and teacher, he touched thousands of lives in Kentucky and around the world. With his characteristic wit and insight, Clark now offers his many admirers one final volume of history—his own.

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447

Publisher

University Press of Kentucky

Published Date

ISBN 10

0813171385

ISBN 13

9780813171388

Black Physicians in the Jim Crow South

By: Thomas J. Ward

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Black Physicians in the Jim Crow South

By: Thomas J. Ward

Drawing on a variety of sources from oral histories to the records of professional organizations, Thomas J. Ward, Jr. examines the development of the African American medical profession in the South. Illuminating the contradictions of race and class, this research provides valuable new insight into class divisions within African American communities in the era of segregation.

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393

Publisher

University of Arkansas Press

Published Date

ISBN 10

1557289360

ISBN 13

9781557289360

Apocalypse in British Art and Visual Culture in the Early Twentieth Century

Some Revelation

By: Thomas Bromwell

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Apocalypse in British Art and Visual Culture in the Early Twentieth Century

Some Revelation

By: Thomas Bromwell

This book is the first substantial study of the presence and relationship with the concepts of apocalypse, eschatology, and millennium in modern British art from 1914 to 1945, addressing how and why practitioners in both religious and secular spheres turned to the subjects. The volume examines British art and visual culture’s relationship with the then-contemporary anxieties and hopes regarding the orientation of society and culture, arguing that there is an acute relationship to the particular forms of cultural discourse of eschatology, apocalypse, and millennium. Chapters identify the continued relevance of religion and religious themes in British art during the period, and demonstrate that eschatology, apocalypse, and millennium were thriving and surprisingly mainstream concepts in the period that remained vital in early to mid-twentieth-century society and culture. This book is a research monograph aimed at an audience of scholars and graduate students already familiar with the core focus of modern British art and cultural histories, especially those working on the late nineteenth and early twentieth centuries, or the concepts of apocalypse, eschatology, and millennium in Theology, Sociology, or other disciplinary settings. It will also be of interest to scholars and students working on war and visual culture, or histories of imperialism. It will benefit scholars of early twentieth-century British art, demonstrating the intersection of art and religion in the modern era, and critically qualifies the standard secular canon and narrative of modern British art, and the general neglect of religion in existing art-historical literature.

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Page Count

327

Publisher

Taylor & Francis

Published Date

ISBN 10

1040256309

ISBN 13

9781040256305

Victorian Childhood

Themes and Variations

By: Thomas Edward Jordan

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Victorian Childhood

Themes and Variations

By: Thomas Edward Jordan

This book presents a broad range of original data on childhood in Victorian Britain. It combines a social science approach to data with historical context, resulting in a highly readable account based on sound historiography. Against a backdrop of the industrial revolution, an expanding economy, and a rising standard of living, Victorian Childhood explores life and death, child development, the family, work, education, social life, cities, crime, and advocacy and reform. Presenting data on the deteriorating health of children during the nineteenth century and on their increasing displacement of adults in the workplace, the author demonstrates that they did not share proportionately in the increased standard of living. Jordan's book is a unique piece of scholarship in its range, focus, and presentation. Original sources such as diaries and memoirs not previously cited elsewhere, literature from the period, and anecdotes from the children themselves animate the statistical background and provide vivid pictures of their lives.

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Page Count

412

Publisher

SUNY Press

Published Date

ISBN 10

0887065449

ISBN 13

9780887065446

Book's by Thomas J. Saunders

Medicinal Chemistry

Medicinal Chemistry

Mammals of Africa

Mammals of Africa

Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice

Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice

Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice E-Book

Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice E-Book

Master Techniques in Orthopaedic Surgery: The Hand

Master Techniques in Orthopaedic Surgery: The Hand

Credit Scoring and Its Applications

Credit Scoring and Its Applications

The Fight of the Century

The Fight of the Century

Feeling Italian

Feeling Italian

Commentary on Aristotle's Politics

Commentary on Aristotle's Politics

Speaking Philosophically

Speaking Philosophically

Hollywood in Berlin

Hollywood in Berlin

My Century in History

My Century in History

Black Physicians in the Jim Crow South

Black Physicians in the Jim Crow South

Apocalypse in British Art and Visual Culture in the Early Twentieth Century

Apocalypse in British Art and Visual Culture in the Early Twentieth Century

Victorian Childhood

Victorian Childhood

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