Discusses the history of the drug, from stone-age time to present day, including its mainstream use as a painkiller and its current status as an illicit narcotic.
Opium and its derivatives morphine and heroin have destroyed, corrupted, and killed individuals, families, communities, and even whole nations. And yet, for most of its long history, opium has also been humanity's most effective means of alleviating physical and mental pain. This extraordinary book encompasses the entire history of the world's most fascinating drug, from the first evidence of poppy cultivation by stone-age man to the present-day opium trade in Afghanistan. Dr. Thomas Dormandy tells the story with verve and insight, uncovering the strange power of opiates to motivate major conflicts yet also inspire great art and medical breakthroughs, to trigger the rise of global criminal networks yet also revolutionize attitudes toward well-being. Opium: Reality's Dark Dream traverses the globe and the centuries, exploring opium's role in colonialism, the Chinese Opium Wars, laudanum-inspired sublime Romantic poetry, American "Yellow Peril" fears, the rise of the Mafia and the black market, 1960s counterculture, and more. Dr. Dormandy also recounts exotic or sad stories of individual addiction. Throughout the book the author emphasizes opium's complex, valuable relationship with developments in medicine, health, and disease, highlighting the perplexing dual nature of the drug as both the cause and relief of great suffering in widely diverse civilizations.
Who were the scientific geniuses behind some of the most innovative and important discoveries in modern medicine? Medical science in the 21st century is continuing to advance, but the character of that advancement is now governed by research teams and committees. Yet in the 19th century – a century when there were many great individual discoveries in medicine – the contributions of four individuals in particular accelerated developments in each of the main branches of medicine. This medical history by Thomas Dormandy focuses on these four individuals and their "moments of truth" - Laennec, a French physician; Semmelweis, a Hungarian obstetrician; Lister, a Scottish surgeon; and Walter Reed, an American army pathologist. They are not well known, compared with their contemporaries in other walks of life, yet their moments of truth transformed the lives of millions. Thomas Dormandy is a retired consultant pathologist (MD, PhD, DSc, FRCS, FRCPath). He is the author of over 300 scientific papers and two books aimed at a general readership, The White Death: A History of Turberculosis , which was short listed for the Aventis prize and RMS book of the month, and Old Masters, a work of art history.
This riveting book takes the reader around the globe and through the centuries to discover how different cultures have sought to combat and treat physical pain. With colorful stories and sometimes frightening anecdotes, Dr. Thomas Dormandy describes a checkered progression of breakthroughs, haphazard experiments, ignorant attitudes, and surprising developments in human efforts to control pain. Attitudes toward pain and its perception have changed, as have the means of pain relief and scientific understanding. Dr. Dormandy offers a thoroughly fascinating, multi-cultural history that culminates with a discussion of today’s successes--and failures--in the struggle against pain. The book’s exploration is fused with accounts of the development of specific methods of pain relief, including the use of alcohol, plants, hypnosis, religious faith, stoic attitudes, local anesthesia, general anesthesia, and modern analgesics. Dr. Dormandy also looks at the most recent advances in pain clinics and palliative care for patients with terminal disease as well as the prospects for loosening pain’s grip in the future.
Hero, adulterer, bon vivant, murderer and rogue, Dan Sickles led the kind of existence that was indeed stranger than fiction. Throughout his life he exhibited the kind of exuberant charm and lack of scruple that wins friends, seduces women, and gets people killed. In American Scoundrel Thomas Keneally, the acclaimed author of Schindler’s List, creates a biography that is as lively and engrossing as its subject. Dan Sickles was a member of Congress, led a controversial charge at Gettysburg, and had an affair with the deposed Queen of Spain—among many other women. But the most startling of his many exploits was his murder of Philip Barton Key (son of Francis Scott Key), the lover of his long-suffering and neglected wife, Teresa. The affair, the crime, and the trial contained all the ingredients of melodrama needed to ensure that it was the scandal of the age. At the trial’s end, Sickles was acquitted and hardly chastened. His life, in which outrage and accomplishment had equal force, is a compelling American tale, told with the skill of a master narrative.
An exploration of the historical origins of the “witches’ ointment” and medieval hallucinogenic drug practices based on the earliest sources • Details how early modern theologians demonized psychedelic folk magic into “witches’ ointments” • Shares dozens of psychoactive formulas and recipes gleaned from rare manuscripts from university collections all over the world as well as the practices and magical incantations necessary for their preparation • Examines the practices of medieval witches like Matteuccia di Francisco, who used hallucinogenic drugs in her love potions and herbal preparations In the medieval period preparations with hallucinogenic herbs were part of the practice of veneficium, or poison magic. This collection of magical arts used poisons, herbs, and rituals to bewitch, heal, prophesy, infect, and murder. In the form of psyche-magical ointments, poison magic could trigger powerful hallucinations and surrealistic dreams that enabled direct experience of the Divine. Smeared on the skin, these entheogenic ointments were said to enable witches to commune with various local goddesses, bastardized by the Church as trips to the Sabbat--clandestine meetings with Satan to learn magic and participate in demonic orgies. Examining trial records and the pharmacopoeia of witches, alchemists, folk healers, and heretics of the 15th century, Thomas Hatsis details how a range of ideas from folk drugs to ecclesiastical fears over medicine women merged to form the classical “witch” stereotype and what history has called the “witches’ ointment.” He shares dozens of psychoactive formulas and recipes gleaned from rare manuscripts from university collections from all over the world as well as the practices and magical incantations necessary for their preparation. He explores the connections between witches’ ointments and spells for shape shifting, spirit travel, and bewitching magic. He examines the practices of some Renaissance magicians, who inhaled powerful drugs to communicate with spirits, and of Italian folk-witches, such as Matteuccia di Francisco, who used hallucinogenic drugs in her love potions and herbal preparations, and Finicella, who used drug ointments to imagine herself transformed into a cat. Exploring the untold history of the witches’ ointment and medieval hallucinogen use, Hatsis reveals how the Church transformed folk drug practices, specifically entheogenic ones, into satanic experiences.
Emphasizing a multidisciplinary team approach, Surgical Reconstruction of the Diabetic Foot and Ankle, 2nd Edition, is an easy-to-follow, well-illustrated guide to the latest surgical techniques in diabetic lower extremity reconstruction. Dr. Thomas Zgonis and an expert team of national and international authors share their extensive knowledge and experience in the surgical treatment of diabetic patients, including challenging clinical scenarios of severe infections, lower extremity deformities, peripheral arterial disease, and soft tissue compromise.
Trust and trustworthiness are core social phenomena, at the heart of most everyday interactions. Yet they are also puzzling: while it matters to us that we place trust well, trusting people who will not let us down, both also seem to involve morally driven attitudes and behaviours. Confronted by whether I should trust another, this tension creates very practical dilemmas. In Trust, Thomas Simpson addresses the foundational question, why should I trust? Philosophical treatments of trust have tended to focus on trying to identify what the attitude of trust consists in. Simpson argues that this approach is misguided, giving rise to merely linguistic debates about how the term 'trust' is used. Instead, he focuses attention on the ways that trust is valuable. The answer defended comprises two claims, which at first seem to be in tension. One is a form of evidentialism about trust: normally, your trust should be based on the evidence you have for someone's trustworthiness. But, second, someone's word is normally enough to settle for you whether you should trust them. Social norms of trustworthiness explain why both are normal. Methodologically innovative, Trust also applies the account , addressing how cultures of trust can be sustained, and the implications of trust in God. While it is a philosophical essay, the book is written in a way that presumes no prior knowledge of philosophy, to be accessible to the scholars from the many disciplines also attracted and puzzled by trust.
In the last 50 years significant numbers of men and women take little exercise in the course of their occupation. The computer keyboard, the rise of private transport, the world by television, household "labour-saving" devices mean that with the minimal of physical effort people work and play. The benefits of doing regular exercise include a reduced risk of: heart disease, stroke, bowel cancer, breast cancer, osteoporosis, and obesity. In addition, many people feel better in themselves during and after exercise. Regular exercise is also thought to help ease stress, anxiety, and mild depression. This book presents new and important research from around the world dealing with various aspects and impacts of exercise as related to health.
“The stories are skillfully told and entirely entertaining . . . An expert, mostly feel-good book about modern medicine” from the award-winning author (Kirkus Reviews, starred review). Behind every landmark drug is a story. It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine. Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book. “[An] absorbing new book.” —The New York Times Book Review “[A] well-written and engaging chronicle.” —The Wall Street Journal “Lucidly informative and compulsively readable.” —Publishers Weekly “Entertaining [and] insightful.” —Booklist “Well-written, well-researched and fascinating to read Ten Drugs provides an insightful look at how drugs have shaped modern medical practices. Towards the end of the book Hager writes that he ‘came away surprised by some of the things he had learned.’ I had the very same reaction.” —Penny Le Couteur, coauthor of Napoleon’s Buttons: How 17 Molecules Changed History
The Washington Manual of Outpatient Internal Medicine is designed as a companion to the Manual of Medical Therapeutics, addressing the most common encounters in outpatient internal medicine - for example, hypertension and diabetes. Disorders treated in the ambulatory setting fall outside traditional internal medicine; therefore, chapters also cover dermatology, otolaryngology, neurology and psychiatry and ophthalmology. The 2nd edition includes a complete update of all chapters.
In the early days on the Colorado frontier, women took care of family and neighbors because accepting that were all in this together was the only realistic survival strategyon the high plains, along the Front Range, in the mountain towns, and on the Western Slope. As dangerous occupations became fundamental to Colorados economy, if they were injured or got sick there was no one to care for the young men who worked as miners, steel workers, cowboys, and railroad construction workers in remote parts of Colorado. So physicians, surgeons, nurses, Catholic Sisters, Reform and Orthodox Jews, Protestants, and other humanitarians established hospitals andwhen Colorado became a mecca for people with tuberculosissanatoriums. Those pioneers and the communities they served created our community-based humanitarian healthcare tradition. These stories about our Wild West heritage honor the legacy of our 19th-century healthcare pioneers and will inspire and entertain 21st-century readers. Because we can be inspired only if we understand the factsand because facts are more likely to be understood when presented in contextthis chronology includes national and international developments that establish an indispensable frame of reference for understanding how our pioneers created the local-community-based healthcare system that weve inherited.
Oxidative Stress and Biomaterials provides readers with the latest information on biomaterials and the oxidative stress that can pose an especially troubling challenge to their biocompatibility, especially given the fact that, at the cellular level, the tissue environment is a harsh landscape of precipitating proteins, infiltrating leukocytes, released oxidants, and fluctuations of pH which, even with the slightest shift in stasis, can induce a perpetual state of chronic inflammation. No material is 100% non-inflammatory, non-toxic, non-teratogenic, non-carcinogenic, non-thrombogenic, and non-immunogenic in all biological settings and situations. In this embattled terrain, the most we can hope for from the biomaterials we design is a type of "meso-compatibility, a material which can remain functional and benign for as long as required without succumbing to this cellular onslaught and inducing a local inflammatory reaction. - Explores the challenges of designing and using biomaterials in order to minimize oxidative stress, reducing patterns of chronic inflammation and cell death - Brings together the two fields of biomaterials and the biology of oxidative stress - Provides approaches for the design of biomaterials with improved biocompatibility
A comprehensive introduction to working with people with learning disabilities, this guide provides the theoretical understanding needed to inform good practice and to help improve the quality of life of people within this group. Using accessible language and case examples, the authors discuss both psychological and practical theories, including: * person-centred and behavioural approaches * anti-discriminatory and anti-oppressive approaches * systems theory * task centred approach * role theory. Emphasising empowerment and inclusion of those with learning disabilities, they relate theory to issues such as loss and bereavement, sexuality and social stigma. They also provide guidance for practitioners on social policy and legislation and explore crisis intervention, values and ethics, advocacy and joint agency work, making this an extremely useful resource for social workers, nurses, teachers care workers and others working with people with learning disabilities.
The Fifth Edition of this best-selling reference is a compendium of evidence-based approaches to the most common presenting complaints. Covering both musculoskeletal and visceral complaints, this text is intended to direct the chiropractor toward an appropriate plan of approach in both diagnostic evaluation and care. Highlighting these approaches are flowcharts (algorithms), relevant historical questioning, and summaries of common conditions related to the presenting complaint. What’s New in the 5th Edition? • Additional disorders added to Selected Causes at the conclusion of chapters • Addition of Likelihood Ratio graphics • Addition of approximately 500 new references • New Appendix: Evidence Based Approach to the Literature • Expanded Appendix: Pharmacology for the Chiropractor includes newer drugs and further explains the classifications of medications mechanisms • Translation into Practice Summary (TIPS) for most of the orthopedic chapters • Updated Algorith
Vitamin C, also known for its role in fighting off the common cold, serves as the antioxidant vitamin. This vitamin helps the body form collagen, a protein that builds bone structure, bone cartilage and blood vessels. Another function of Vitamin C is its absorption of iron, which aids in bone maintenance for stronger bodies and cleaner teeth. This can be accomplished by keeping a well balanced diet and eating healthy. In addition, Vitamin C assists in fighting off cardiovascular disease as well. But not only does Vitamin C aid the human body. Researchers have studied the affects Vitamin C holds upon other living organisms, such as plant cells. This book dives into cutting edge research on Vitamin C and its many functions in the earth's natural environment.
Current Therapy in Vascular and Endovascular Surgery is an ideal medical reference book to consult for information in this ever-changing field! Thoroughly revised to reflect the most recent innovations in vascular and endovascular surgery, it features more than 150 chapters on topics new to this edition, and equips residents and practitioners alike with the latest procedures and techniques in this rapidly growing area. Internationally recognized experts present expanded coverage of a wide array of topics, keeping you abreast of all of today's developments! Consult this title on your favorite device, conduct rapid searches, and adjust font sizes for optimal readability. Quickly locate key information with concise, to-the-point chapters. Prepare for boards or certification exams through coverage that spans the entire spectrum of vascular surgery. Explore brand-new coverage of endovascular procedures and techniques. Learn from leaders in the field, including internationally recognized editors and numerous global experts in specialized disciplines. Access in-depth, detailed coverage of various vascular diseases, each sub-divided into discrete topics for a more focused approach. View procedures more clearly than ever before with the help of more than 800 full-color illustrations throughout. Access the full text and videos online at Expert Consult.
Geared to primary care practitioners, The Washington Manual® of Outpatient Internal Medicine focuses on common ambulatory medical problems encountered in each medical subspecialty. The book has a quick-reference format similar to The Washington Manual® of Medical Therapeutics, with a standard chapter template, a bulleted style, numerous tables and figures, and a two-color design. All chapters are written by house staff and faculty at Barnes-Jewish Hospital and Washington University School of Medicine. Coverage includes the traditional internal medicine subspecialties and other areas where problems are frequently seen in the ambulatory setting, such as dermatology, neurology, ophthalmology, otolaryngology, and psychiatry. Most subspecialties have separate symptom- and disease-based chapters. The Washington Manual® is a registered mark belonging to Washington University in St. Louis to which international legal protection applies. The mark is used in this publication by LWW under license from Washington University.
To address the exponential growth in the fields of pediatric hematology and oncology, this classic reference has been separated into two distinct volumes. With this volume, devoted strictly to pediatric hematology, and another to pediatric oncology, you’ll keep you on the cutting-edge of these two specialties. The completely revised 7th edition of Nathan and Oski’s Hematology of Infancy and Childhood is now in full color, and provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with hematologic disorders. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of blood diseases that you encounter in everyday practice. Written by the leading names in pediatric hematology, this resource is an essential tool for anyone involved in caring for children with hematologic disorders. Balances summaries of relevant pathophysiology with clear, practical clinical guidance to help you thoroughly understand the underlying science of diseases. Offers comprehensive coverage of all hematologic disorders, including newly recognized ones, along with the latest breakthroughs in diagnosis and management. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines at a glance. Presents an all-new full-color design that includes clear illustrative examples of relevant science and clinical problems for quick access to the answers you need.
Efficiently review the latest clinical recommendations, developments, and procedures with Women's Health Review. This comprehensive, yet succinct summary is just the medical reference book you need to ensure that your knowledge is up to date! Zero in on the most important new information with "update boxes," and dig deeper into the surrounding text for more background or complementary discussions. Review key points quickly with the aid of relevant tables and images. Take an organized approach to review with a subspecialty-based structure and a convenient outline format. Get the authoritative coverage you need thanks to the collaboration of contributions from University of California medical schools, each at the top of their specialty. Access the fully searchable contents online at www.expertconsult.com. The resource you need to stay on top of the latest recommendations and updates in Obstetrics and Gynecology
Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. - Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. - Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. - Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. - Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. - Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. - Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. - Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.
This riveting book takes the reader around the globe and through the centuries to discover how different cultures have sought to combat and treat physical pain. With colorful stories and sometimes frightening anecdotes, Dr. Thomas Dormandy describes a checkered progression of breakthroughs, haphazard experiments, ignorant attitudes, and surprising developments in human efforts to control pain. Attitudes toward pain and its perception have changed, as have the means of pain relief and scientific understanding. Dr. Dormandy offers a thoroughly fascinating, multi-cultural history that culminates with a discussion of today’s successes--and failures--in the struggle against pain. The book’s exploration is fused with accounts of the development of specific methods of pain relief, including the use of alcohol, plants, hypnosis, religious faith, stoic attitudes, local anesthesia, general anesthesia, and modern analgesics. Dr. Dormandy also looks at the most recent advances in pain clinics and palliative care for patients with terminal disease as well as the prospects for loosening pain’s grip in the future.
The Fourth Edition of this best-selling reference is a compendium of evidence-based approaches to the most common presenting complaints. Covering both musculoskeletal and visceral complaints, this text is intended to direct the chiropractor toward an appropriate plan of approach in both diagnostic evaluation and care. Highlighting these approaches are flowcharts (algorithms), relevant historical questioning, and summaries of common conditions related to the presenting complaint. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.
Who were the scientific geniuses behind some of the most innovative and important discoveries in modern medicine? Medical science in the 21st century is continuing to advance, but the character of that advancement is now governed by research teams and committees. Yet in the 19th century – a century when there were many great individual discoveries in medicine – the contributions of four individuals in particular accelerated developments in each of the main branches of medicine. This medical history by Thomas Dormandy focuses on these four individuals and their "moments of truth" - Laennec, a French physician; Semmelweis, a Hungarian obstetrician; Lister, a Scottish surgeon; and Walter Reed, an American army pathologist. They are not well known, compared with their contemporaries in other walks of life, yet their moments of truth transformed the lives of millions. Thomas Dormandy is a retired consultant pathologist (MD, PhD, DSc, FRCS, FRCPath). He is the author of over 300 scientific papers and two books aimed at a general readership, The White Death: A History of Turberculosis , which was short listed for the Aventis prize and RMS book of the month, and Old Masters, a work of art history.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The long-awaited new edition of the world's most widely used and highly regarded textbook and reference of emergency medicine A Doody's Core Title for 2019! Tintinalli’s Emergency Medicine is THE essential resource for everyone working in, and teaching emergency medicine. The Ninth Edition provides the depth and breadth of coverage that reflects the complexity and expertise needed to practice emergency medicine in today’s fast-paced environments. This comprehensive text is an important clinical resource for physicians, residents and students, advance practice providers, emergency nurses, EMTs, and paramedics. It is a necessary resource for in-training and board examinations, and recertification. Tintinalli’s Emergency Medicine covers everything from prehospital care, disaster preparedness, and basic and advanced resuscitative techniques, to all the significant medical, traumatic, and environmental conditions requiring emergency treatment in adults, children and neonates. Highlights of the Ninth Edition: • Full-color design with more tables than ever to succinctly present key information • Extensive updates to all sections, incorporating the latest clinical and evidence-based information • Online access to over 100 videos, covering a wide range of diagnostic and therapeutic procedures, and POCUS for obstetric/gynecologic, pediatric, musculoskeletal, and vascular conditions • World-class pediatric section on the care of neonates, infants, and children • Expanded chapters on the management of gynecologic and obstetric conditions and emergencies • Updated information on toxicologic and environmental emergencies • Contemporary, concise discussion of ED identification and treatment of opioid use disorders • Updated information on procedural sedation • Expert advice on the management and care of transgender patients • Latest information available on neurologic and cardiac emergencies From the reviews of the seventh edition: "Collectively, they have once again produced an excellent text that manages to cover the broad scope of emergency medicine while remaining an easily readable and practical resource....Last, for the inevitable comparison of this current edition of Tintinalli's Emergency Medicine with other available emergency medicine textbooks available: in my opinion, Tintinalli’s still comes out on top. It is more concise and easier to read than some, yet it covers the breadth of emergency medicine practice more comprehensively than others....Just as previous editions did, the seventh presents all of the most pertinent and up-to-date information in a well-organized format that is comprehensive yet easy to read. That and many of the attractive new features in this current edition will ensure its place on my bookshelf for years to come."―JAMA
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