Deep Learning through Sparse Representation and Low-Rank Modeling bridges classical sparse and low rank models-those that emphasize problem-specific Interpretability-with recent deep network models that have enabled a larger learning capacity and better utilization of Big Data. It shows how the toolkit of deep learning is closely tied with the sparse/low rank methods and algorithms, providing a rich variety of theoretical and analytic tools to guide the design and interpretation of deep learning models. The development of the theory and models is supported by a wide variety of applications in computer vision, machine learning, signal processing, and data mining. This book will be highly useful for researchers, graduate students and practitioners working in the fields of computer vision, machine learning, signal processing, optimization and statistics.
How oxygen levels in Earth's atmosphere and oceans evolved has always been a central question in Earth System Science. Researchers have developed numerous tracers to tackle this question, utilizing geochemical characteristics of different elements. Iodine incorporated in calcium carbonate (including biogenic) minerals, reported as I/Ca, is a proxy for dissolved oxygen in seawater. Here we review the rationale behind this proxy, its recent applications and some potential future research directions.
Around the globe, besides fungal and bacterial diseases, both virus and viroid diseases have acquired greater importance in the realm of plant pathology and call for effective management measures as they are responsible for heavy yield losses and are a matter of vital importance and concern to farmers, horticulturists, gardeners and foresters. Understanding disease epidemiology is of vital importance for formulating viable disease management practices in a given agro-ecosystem. The development and progress of plant disease epidemics are variable from region to region. Epidemiology is not a static process, but rather a dynamic course that varies with a change in the ecology, host, vector and virus systems.
The presence of concentrations of organic substances and cations in seawater is a matter of increasing concern to the water industry, environmentalists and the general public alike. It poses a threat of possible health hazards for humans, fish and crustacea. Until fairly recently, the analysis of seawater was limited to a number of major constituen
For a chemist who is concerned with the synthesis of new energetic compounds, it is essential to be able to assess physical and thermodynamic properties, as well as the sensitivity, of possible new energetic compounds before synthesis is attempted. Various approaches have been developed to predict important aspects of the physical and thermodynamic properties of energetic materials including (but not limited to): crystal density, heat of formation, melting point, enthalpy of fusion and enthalpy of sublimation of an organic energetic compound. Since an organic energetic material consists of metastable molecules capable of undergoing very rapid and highly exothermic reactions, many methods have been developed to estimate the sensitivity of an energetic compound with respect to detonationcausing external stimuli such as heat, friction, impact, shock and electrostatic discharge. This book introduces these methods and demonstrates those methods which can be easily applied.
Through four editions, Cummings Otolaryngology has been the world's most trusted source for comprehensive guidance on all facets of head and neck surgery. This 5th Edition - edited by Paul W. Flint, Bruce H. Haughey, Valerie J. Lund, John K. Niparko, Mark A. Richardson, K. Thomas Robbins, and J. Regan Thomas – equips you to implement all the newest discoveries, techniques, and technologies that are shaping patient outcomes. You'll find new chapters on benign neoplasms, endoscopic DCR, head and neck ultrasound, and trends in surgical technology... a new section on rhinology... and coverage of hot topics such as Botox. Plus, your purchase includes access to the complete contents of this encyclopedic reference online, with video clips of key index cases! Overcome virtually any clinical challenge with detailed, expert coverage of every area of head and neck surgery, authored by hundreds of leading luminaries in the field. See clinical problems as they present in practice with 3,200 images - many new to this edition. Consult the complete contents of this encyclopedic reference online, with video clips of key index cases! Stay current with new chapters on benign neoplasms, endoscopic DCR, head and neck ultrasound, and trends in surgical technology... a new section on rhinology... and coverage of hot topics including Botox. Get fresh perspectives from a new editorial board and many new contributors. Find what you need faster through a streamlined format, reorganized chapters, and a color design that expedites reference.
This book is the most up-to-date publication on fluorescence diagnostic (FDAP) and photodynamic therapy (PDT) methods used in dermatology. Both techniques are presently world wide introduced as standards for the delineation and the treatment of cutaneous precancerous stages and tumors, which show steadily increasing numbers due to e.g. more frequent sun exposure. Summarizing experiences on more than 5.000 treated patients, it offers a comprehensive information on every aspect of skin tumor detection and treatment. The main part of the book focuses on the clinical aspects giving detailed descriptions on skin tumor detection as well as photodynamic treatment of selected diseases (solar keratoses, basal cell carcinomas, squamous cell carcinomas, Bowen's disease, psoriasis lesions, etc.). The clinically oriented chapters are supplemented by practical guidelines for PDT and FDAP. The included atlas is comprised of 270 high quality color figures allowing daily use as a handbook.
Development of the Nervous System, Fourth Edition provides an informative and up-to-date account of our present understanding of the basic principles of neural development as exemplified by key experiments and observations from past and recent times. This book reflects the advances made over the last few years, demonstrating their promise for both therapy and molecular understanding of one of the most complex processes in animal development. This information is critical for neuroscientists, developmental biologists, educators, and students at various stages of their career, providing a clear presentation of the frontiers of this exciting and medically important area of developmental biology. The book includes a basic introduction to the relevant aspects of neural development, covering all the major topics that form the basis of a comprehensive, advanced undergraduate and graduate curriculum, including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, neuron survival and death, synapse formation and plasticity. - Provides broad coverage of concepts and experimental strategies - Includes full color schematics and photographs of critical experiments - Outlines the molecular and genetic basis for most developmental events - Written at a level that is appropriate for advanced undergraduates and beyond - Includes designs of critical experiments that are easy to understand
This book explores various topics relevant to understanding the complexities of biological effects generated by solar radiation. Solar-energy-absorbing substances are evaluated, including sunscreen agents, and their influence on cancers and diseases. One assumption is the use of sunscreen agents cannot prevent the photoinitiation of biological system malfunction, such as immunosuppression. On the contrary, sunscreens can help enhance the negative solar-energy-induced effects, such as by skin penetration. This collection offers critical appraisals of clinical studies involving vitamins and nonsteroidal anti-inflammatory agents for alleviating, mitigating, or even curing of various inflammatory diseases including cancers.
This brand-new, full-color reference is a foundational text for veterinarians and veterinary students learning about companion exotic animal diseases. Organized by body system, Current Therapy in Exotic Pet Practice walks students through the most relevant information concerning the diagnosis and treatment of exotic animals - including the most relevant information on anatomy, physical examination, diagnostic testing, disease conditions, therapeutics, epidemiology of diseases, and zoonoses. Topics such as captive care, current standards of care for all exotic species, veterinary clinical epidemiology, and the effective prevention and management of infectious diseases are also included. Expert guidance on treating various disease conditions provides authoritative support for veterinarians who are less experienced in companion exotic pet care. Renowned authors and editors carefully selected topics of real clinical importance. Detailed coverage on how to identify and treat diseases (from common to rare) helps alleviate apprehension a veterinarian may feel when treating an unfamiliar species. Includes the latest information from the current scientific literature and addresses hot topics associated with treating companion exotic animals today. Vivid full-color images demonstrate the unique anatomic and medical features of each group of animals covered.
With expert contributions from experienced educators, research scientists and clinicians, Foye’s Principles of Medicinal Chemistry, Eighth Edition is an invaluable resource for professional students, graduate students and pharmacy faculty alike. This ‘gold standard’ text explains the chemical basis of drug action, emphasizing the structure-activity relationships, physicochemical-pharmacokinetic properties, and metabolic profiles of the most commonly used drugs.
Nunn's Applied Respiratory Physiology, Ninth Edition, is your concise, one-stop guide to all aspects of respiratory physiology in health, disease, and in the many physiologically challenging situations and environments into which humans take themselves – coverage is from basic science to clinical applications. Trusted for over 50 years, this most comprehensive single volume on respiratory physiology will prove invaluable to those in training or preparing for examinations in anaesthesia, intensive care, respiratory medicine or thoracic surgery – as well as an essential quick reference for physiologists and the range of practitioners requiring ready access to current knowledge in this field. Now fully revised and updated, this ninth edition includes a larger page format for improved clarity, as well as full access to the complete, downloadable eBook version. This incorporates BONUS chapters, handy topic summaries, interactive self-assessment material and a NEW series of expert lectures on key topics. The result is a more flexible, engaging and complete resource than ever before. Enhancements to this edition include: - A new dedicated chapter on obesity – covering the effects of this global challenge on the physiology of the respiratory system in health and disease, in both adults and children - Expanded coverage of the adverse effects of hyperoxia - including the physiology of the now popular technique of high-flow nasal therapy - A revised section on air pollution – reflecting the growing importance and understanding of the impact of pollution on the lungs and other body systems, along with the latest worldwide guidelines - Detailed coverage of artificial ventilation during general anaesthesia – covering post-operative respiratory complications and the physiological basis of current best-practice for optimizing ventilation - Print comes with enhanced eBook - includes access to the complete, fully searchable text, PLUS: - bonus chapters - handy chapter summaries - interactive self-assessment material - a NEW series of 25 expert lectures focusing on the most essential topics in respiratory physiology
Offering today's most authoritative, comprehensive coverage of sleep disorders, Kryger's Principles and Practice of Sleep Medicine, 7th Edition, is a must-have resource for sleep medicine specialists, fellows, trainees, and technicians, as well as pulmonologists, neurologists, and other clinicians who see patients with sleep-related issues. It provides a solid understanding of underlying basic science as well as complete coverage of emerging advances in management and treatment for a widely diverse patient population. Evidence-based content, hundreds of full-color illustrations, and a wealth of additional resources online help you make well-informed clinical decisions and offer your patients the best possible care. - Contains new chapters on sleep in intersex and transgender individuals; sleep telemedicine and remote PAP adherence monitoring; and sleep and the menstrual cycle, as well as increased coverage of treatment and management of pediatric patients. - Includes expanded sections on pharmacology, sleep in individuals with other medical disorders, and methodology. - Discusses updated treatments for sleep apnea and advancements in CPAP therapy. - Offers access to 95 video clips online, including expert interviews and sleep study footage of various sleep disorders. - Meets the needs of practicing clinicians as well as those preparing for the sleep medicine fellowship examination or recertification exams, with more than 950 self-assessment questions, answers, and rationales online. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
This book presents a detailed study of a system of interacting Brownian motions in one dimension. The interaction is point-like such that the n-th Brownian motion is reflected from the Brownian motion with label n-1. This model belongs to the Kardar-Parisi-Zhang (KPZ) universality class. In fact, because of the singular interaction, many universal properties can be established with rigor. They depend on the choice of initial conditions. Discussion addresses packed and periodic initial conditions (Chapter 5), stationary initial conditions (Chapter 6), and mixtures thereof (Chapter 7). The suitably scaled spatial process will be proven to converge to an Airy process in the long time limit. A chapter on determinantal random fields and another one on Airy processes are added to have the notes self-contained. These notes serve as an introduction to the KPZ universality class, illustrating the main concepts by means of a single model only. The notes will be of interest to readers from interacting diffusion processes and non-equilibrium statistical mechanics.
The most comprehensive, multi-disciplinary text in the field, Cummings Otolaryngology: Head and Neck Surgery, 7th Edition, provides detailed, practical answers and easily accessible clinical content on the complex issues that arise for otolaryngologists at all levels, across all subspecialties. This award-winning text is a one-stop reference for all stages of your career—from residency and board certification through the challenges faced in daily clinical practice. Updated content, new otology editor Dr. Howard W. Francis, and new chapters and videos ensure that this 7th Edition remains the definitive reference in today's otolaryngology. - Brings you up to date with the latest minimally invasive procedures, recent changes in rhinology, and new techniques and technologies that are shaping patient outcomes. - Contains 12 new chapters, including Chronic Rhinosinusitis, Facial Pain, Geriatric Otology, Middle Ear Endoscopic Surgery, Pediatric Speech Disorders, Pediatric Cochlear Implantation, Tongue-Ties and Lip Ties, Laryngotracheal Clefts, and more. - Covers recent advances and new approaches such as the Draf III procedure for CRS affecting the frontal recess, endoscopic vidian and posterior nasal neurectomy for non-allergic rhinitis, and endoscopic approaches for sinonasal and orbital tumors, both extra- and intraconal. - Provides access to 70 key indicator (Accreditation Council for Graduate Medical Education Key Indicator Procedures), and surgical videos – an increase of 43% over the previous edition. - Offers outstanding visual support with 4,000 high-quality images and hundreds of quick-reference tables and boxes. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
The partnership between India and Taiwan is situated in a virtual maze of complex political factors. Given the core issue of contestation of Taiwan’s political status in world affairs and India’s adherence to the “One China” policy, the relationship remains a fragile one for both partners. In recent years, Taiwan has signed the Cross-Strait Economic Cooperation Framework Agreement (ECFA) with Mainland China. Increasingly, its political and economic future (including its relationships with countries such as India) will continue to be linked with Mainland China. This book closely examines the partnership between India and Taiwan within the new post-ECFA setting that Taiwan finds itself in. It explicates the shifts and continuities in Taiwan’s economic relationship with Mainland China, discusses how partnership with India could become a crucial pivot of Taiwan’s foreign policy in the coming years, and argues why this partnership is vital for the “take-off ” of India’s own economic growth targets. The book identifies specific avenues for India and Taiwan to benefit from the economic growth success stories that they have come to represent over these years and outlines policy realignments that could allow India and Taiwan to best realize their mutuality of interests.
A timely, outstanding educational resource dedicated to explaining the new method of performing corneal transplantation without the use of corneal sutures and an absence of full-thickness corneal wound. This comprehensive book includes a discussion of the development of lamellar transplantation; an in-depth discussion of the basic science of corneal structure, physiology, biomechanics and pathology; a primer on advanced corneal imaging; and a review of the surgical techniques and instrumentation required.
This book examines the current state of the art, new challenges, opportunities, and applications of IPNs. With contributions from experts across the globe, this survey is an outstanding resource reference for anyone involved in the field of polymer materials design for advanced technologies. • Comprehensively summarizes many of the recent technical research accomplishments in the area of micro and nanostructured Interpenetrating Polymer Networks • Discusses various aspects of synthesis, characterization, structure, morphology, modelling, properties, and applications of IPNs • Describes how nano-structured IPNs correlate their multiscale structure to their properties and morphologies • Serves as a one-stop reference resource for important research accomplishments in the area of IPNs and nano-structured polymer systems • Includes chapters from leading researchers in the IPN field from industry, academy, government and private research institutions
This book is intended for scientists and engineers who need to know about surface roughness, how to measure and describe it and what practical problems it might cause them. The original Rough Surfaces was widely accepted as the definitive work on the subject; this is a completely new edition, updated to take account of recent major advances in measurement and characterisation. Modern instruments are introduced, including laser interferometers and AFM's, and there are sections on fractals and motif analysis. Problems of 3D surface measurement and description are extensively treated. Manufacturing and production engineers, optical and QC engineers, tribologists and many other applied scientists will find this book an essential addition to their libraries.
This book examines the current state of the art, new challenges, opportunities, and applications in the area of polymer nanocomposites. Special attention has been paid to the processing-morphology-structure-property relationship of the system. Various unresolved issues and new challenges in the field of polymer nanocompostes are discussed. The infl
Clay–Polymer Nanocomposites is a complete summary of the existing knowledge on this topic, from the basic concepts of synthesis and design to their applications in timely topics such as high-performance composites, environment, and energy issues. This book covers many aspects of synthesis such as in- situ polymerization within the interlamellar spacing of the clays or by reaction of pristine or pre-modified clays with reactive polymers and prepolymers. Indeed, nanocomposites can be prepared at industrial scale by melt mixing. Regardless the synthesis method, much is said in this book about the importance of theclay pre-modification step, which is demonstrated to be effective, on many occasions, in obtaining exfoliated nanocomposites. Clay–Polymer Nanocomposites reports the background to numerous characterization methods including solid state NMR, neutron scattering, diffraction and vibrational techniques as well as surface analytical methods, namely XPS, inverse gas chromatography and nitrogen adsorption to probe surface composition, wetting and textural/structural properties. Although not described in dedicated chapters, numerous X-ray diffraction patterns of clay–polymer nanocomposites and reference materials are displayed to account for the effects of intercalation and exfoliations of layered aluminosilicates. Finally, multiscale molecular simulation protocols are presenting for predicting morphologies and properties of nanostructured polymer systems with industrial relevance. As far as applications are concerned, Clay–Polymer Nanocomposites examines structural composites such as clay–epoxy and clay–biopolymers, the use of clay–polymer nanocomposites as reactive nanocomposite fillers, catalytic clay-(conductive) polymers and similar nanocomposites for the uptake of hazardous compounds or for controlled drug release, antibacterial applications, energy storage, and more. - The most comprehensive coverage of the state of the art in clay–polymer nanocomposites, from synthesis and design to opportunities and applications - Covers the various methods of characterization of clay–polymer nanocomposites - including spectroscopy, thermal analyses, and X-ray diffraction - Includes a discussion of a range of application areas, including biomedicine, energy storage, biofouling resistance, and more
Get the authoritative, up-to-date information you need on liver disease from the 7th Edition of the most trusted reference worldwide. Covering both basic science and recent clinical developments, this revised edition by Drs. Arun J. Sanyal, Thomas D. Boyer, Norah A. Terrault, and Keith D. Lindor, provides an in-depth, comprehensive look at the pathophysiology, diagnostic, and treatment information related to the liver. More than 1,100 figures and tables, many new and in full color, highlight completely updated content throughout. - Expert, international authorship and comprehensive, easy-to-access information makes this edition the gold standard in the field of hepatology. - Includes new information on the rapid changes in treatment paradigms for acute liver failure, the latest treatments for primary biliary cholangitis, full coverage of the gut microbiome and its role in liver disease, the newest developments in drug-induced liver injury, and changes in hepatitis C virus treatment and hot-button concerns about access to care. - New summary boxes at the end of each chapter and a newly streamlined table of contents make it easier to find and understand the information you're looking for. - Hundreds of brand-new illustrations clearly present key aspects of liver disease.
Organized on a combined basis of chronology and of structural and functional hierarchy, This comprehensive text describes all aspects of proteins--biosynthesis, evolution, dynamics, ligand binding, catalysis, and energy transduction--not just their structures. This edition (first was 1984) is thoroughly updated--especially in the area of protein biosynthesis--and features end-of-chapter exercises and problems, many of which require the student to consult the cited literature in order to obtain the answer. Annotation copyright by Book News, Inc., Portland, OR
For nearly 30 years, Dr. Meir Kryger’s must-have guide to sleep medicine has been the gold standard in this fast-changing field. This essential, full-color reference includes more than 20 unique sections and over 170 chapters covering every aspect of sleep disorders, giving you the authoritative guidance you need to offer your patients the best possible care. Evidence-based content helps you make the most well-informed clinical decisions. An ideal resource for preparing for the sleep medicine fellowship examination. New content on sleep apnea, neurological disorders, legal aspects of sleep medicine, dental sleep medicine genetics, circadian disorders, geriatrics, women’s health, cardiovascular diseases, and occupational sleep medicine, keeps you fully up to date. Updates to scientific discoveries and clinical approaches ensure that you remain current with new knowledge that is advancing the diagnosis and management of sleep disorders.
Comprehensive and lavishly illustrated, McKee's Pathology of the Skin, 5th Edition, is your reference of choice for up-to-date, authoritative information on dermatopathology. You'll find clinical guidance from internationally renowned experts along with details on etiology, pathogenesis, histopathology, and differential diagnosis – making this unique reference unparalleled in its wealth of clinical and histopathological material. The 5th Edition of this classic text is a must-have resource for practicing dermatopathologists and general pathologists who sign out skin biopsies. - Covers pathological aspects of skin diseases in addition to providing superb descriptions and illustrations of their clinical manifestations – the only available reference with this unique combination of features. - Integrates dermatopathology, clinical correlations, and clinical photographs throughout, and features bulleted lists of clinical features and differential diagnosis tables for easy reference. - Contains more than 5,000 superb histopathologic and clinical illustrations that demonstrate the range of histologic manifestations. - Brings you fully up to date with key molecular aspects of disease, the capabilities and limitations of molecular diagnostics, and targeted/personalized medicine. - Features up-to-date information on biologics, drug eruptions, and other developments in therapeutics. - Helps you stay current with the latest diagnostic tumor markers and other new developments in immunohistochemistry. - Includes a completely revised chapter on cutaneous lymphoma that reflects recent WHO-EORTC classification changes, as well as new coverage of sentinel lymph node biopsy for melanoma. - Shares the knowledge of the main editor Dr. J. Eduardo Calonje, along with co-editors Thomas Brenn, and Alexander Lazar, and new co-editor Steven D. Billings who offers expertise on both dermatopathology and soft tissue tumors. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Authored by a team of experts, the new edition of this bestseller presents practical techniques for managing inventory and production throughout supply chains. It covers the current context of inventory and production management, replenishment systems for managing individual inventories within a firm, managing inventory in multiple locations and firms, and production management. The book presents sophisticated concepts and solutions with an eye towards today’s economy of global demand, cost-saving, and rapid cycles. It explains how to decrease working capital and how to deal with coordinating chains across boundaries.
Your students are curious. Here is a text that shows them how psychology answers the questions they are asking. In this introduction to psychology, Wind Goodfriend, Gary Lewandowski, Charity Brown Griffin, and Tom Heinzen investigate our everyday curiosities through psychological science – approaching the discipline′s core tenets with candor, humor, and wonder. Psychology and Our Curious World invites students to ask questions, think critically, and make evidence-informed decisions to better understand their unique world and that of others. Amplifying the impact of their work, all the authors are donating a portion of their royalties to charities close to their hearts, including: The Trevor Project, Thurgood Marshall College Fund, Make-A-Wish Foundation, Wounded Warrior Project, and GlassRoots. Watch this video walkthrough and see how it works:
Praise for the prior edition "The author has done a magnificent job... this book is highly recommended for introducing biophysics to the motivated and curious undergraduate student." ―Contemporary Physics "a terrific text ... will enable students to understand the significance of biological parameters through quantitative examples―a modern way of learning biophysics." ―American Journal of Physics "A superb pedagogical textbook... Full-color illustrations aid students in their understanding" ―Midwest Book Review This new edition provides a complete update to the most accessible yet thorough introduction to the physical and quantitative aspects of biological systems and processes involving macromolecules, subcellular structures, and whole cells. It includes two brand new chapters covering experimental techniques, especially atomic force microscopy, complementing the updated coverage of mathematical and computational tools. The authors have also incorporated additions to the multimedia component of video clips and animations, as well as interactive diagrams and graphs. Thomas Nordlund is professor emeritus in the Department of Physics at The University of Alabama at Birmingham. He is an elected fellow of the American Physical Society and has been studying biomolecular dynamics for over thirty years. Peter M. Hoffmann is a professor in the Department of Physics and Astronomy at Wayne State University in Detroit, Michigan, where he founded the biomedical physics program. He has been involved in soft matter and biophysics research for twenty-five years, and earned his PhD in materials science and engineering from Johns Hopkins University.
This superbly illustrated book presents the most current and comprehensive review of oral anatomy for clinicians and researchers alike. In 26 chapters, the reader is taken on a unique anatomical journey, starting with the oral fissure, continuing via the maxilla and mandible to the tongue and floor of the mouth, and concluding with the temporomandibular joint and masticatory muscles. Each chapter offers a detailed description of the relevant anatomical structures and their spatial relationships, provides quantitative morphological assessments, and explains the relevance of the region for clinical dentistry. All dental health care professionals require a sound knowledge of anatomy for the purposes of diagnostics, treatment planning, and therapeutic intervention. A full understanding of the relationship between anatomy and clinical practice is the ultimate objective, and this book will enable the reader to achieve such understanding as the basis for provision of the best possible treatment for each individual patient as well as recognition and comprehension of unexpected clinical findings.
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