Speakers, writers, and everyone who likes to laugh will grab this witty compilation of fast, funny remarks right off the shelf. The humorous collection, with amusing illustrations throughout, includes side-splitting quotes and comic observations from Bill Cosby, Rodney Dangerfield, Jerry Seinfeld, Groucho Marx, Lucille Ball, Mae West, Oscar Wilde, and many others. In addition to the roasts and toasts, there are one-liners perfect for easing a situation and charming an audience.
There is no such thing as fun for the entire family."--Jerry Seinfeld. That's an example of a one-liner. It packs a wealth of meaning into a few words and produces a chuckle along with its wisdom. Here's another one: "My luck--I was waiting at the airport when my ship came in."--Henny Youngman. There are many more laugh-inducing one-liners like these in this collection! Some are attributed to famous people; others have no source. They span many different topics. One thing's for sure. These one-liners not only say something, but they say it in a memorable way. Here are two more: * "Money is better than poverty, if only for financial reasons."--Woody Allen. * "I was so ugly as a kid we never had a jack-o'-lantern. They just stuck me in the window."--Rodney Dangerfield. Perrett lives in Westlake Village, GA. 512 pages, 4 3/16 x 5 1/4.
Enjoy this sidesplitting collection of hundreds of fast, funny remarks and observations. Spanning a wide range of topics, and including one-liners from Milton Berle, George Bums, Bob Hope, and other great comedians past and present, this witty compilation is a gold mine for speakers, writers, and anyone who likes to laugh.
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research. - Highlights changes surrounding strategies for drug discovery, providing a comprehensive reference and featuring advances in the methods involved - Includes multiple new sections, such as development and utilization of models in pharmacology, de-orphanization of new drug targets, predicting impact of disease on drug pharmacokinetics, and the impact of enzyme kinetics on drug-drug interactions - Illustrates the application of rapid inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data
First Published in 2015. This encyclopaedic collection includes Volumes 1 (A-L) and 2 (M-Z) as well as essays on the settlement of America. It can be argued that the westward expansion occurred only one week after the English landfall at Jamestown, Virginia, on May 14, 1607. Beginning on May 21, Captain John Smith, one of the colonization company’s leaders, and twenty-one companions made their way northwest up the James River for some 50 or 60 miles (80 or 96 km).
Enjoy this sidesplitting collection of hundreds of fast, funny remarks and observations. Spanning a wide range of topics, and including one-liners from Milton Berle, George Bums, Bob Hope, and other great comedians past and present, this witty compilation is a gold mine for speakers, writers, and anyone who likes to laugh.
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