Bioconjugate Techniques, 2nd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or cross linking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. A one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates More than 600 figures that visually describe the complex reactions associated with the synthesis of bioconjugates Includes entirely new chapters on the latest areas in the field of bioconjugation as follows: Microparticles and nanoparticlesSilane coupling agentsDendrimers and dendronsChemoselective ligationQuantum dotsLanthanide chelatesCyanine dyesDiscrete PEG compoundsBuckyballs,fullerenes, and carbon nanotubesMass tags and isotope tagsBioconjugation in the study of protein interactions
The book has been divided into the 5 major sections covering the following: Section I: Covers on the articles focused towards the major themes of strengthening Technology Application and Delivery systems, ICT, BLESS, NRM and women empowerment.
To present a coherent and meaningful survey of scientific research endeavour in an area that has expanded as fast as physiology and biochemistry of reproduction in the male is no mean task these days. No less prodigious than the growth of knowledge of male reproductive function has been the rate at which the outpouring of publications on this subject has continued since the appearance of 'The Biochemistry of Semen and of the Male Reproductive Tract' in 1964. Since cyclopaedic treatment of this vast literature did not appeal to us, we have made no attempt either to rehash the material contained in that book or to enlarge the bibliography beyond the nearly 3500 references included in the present treatise. At the same time, whilst writing, we felt strongly that to advance, it is necessary to understand the past, and for this reason we have not hesitated to refer (especially in the introductory chapter) to a number of those fundamental early discoveries in which today's knowledge is deeply and firmly rooted.
Gonadotropins: From Bench Side to Bedside, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on all aspects of gonadotropins, from research to treatment. Contains contributions from leading authorities on the topic Publishes cutting-edge reviews in molecular biology Informs and updates on all the latest developments available regarding the research of gonadotropins
Biocorrosion refers to corrosion influenced by bacteria adhering to surfaces in biofilms. Biocorrosion is a major problem in areas such as cooling systems and marine structures where biofilms can develop. This book summarises key recent research in this subject. Part one looks at theories of biocorrosion and measurement techniques. Part two discusses how bacteria and biofilms result in biocorrosion. The final part of the book includes case studies of biocorrosion in areas as diverse as buildings, fuels, marine environments and cooling systems. Provides a detailed overview of biocorrosion and the different scientific and/or industrial problems related to microbially induced corrosion Introduces a variety of investigative techniques and methodologies that are employed in diagnosing and evaluating microbially induced corrosion Includes case studies on: biodeterioration of building materials; biocorrosion issues associated with diesel and biofuels; marine biocorrosion; corrosion of open recirculating cooling water systems and cooling system components; the effect of H2S on steel corrosion
This book contains a series of clinical cases that address and illustrate difficult problems in obstetric ultrasound. The approach is strongly didactic and will aid trainees in maternal-fetal medicine and obstetrics to appreciate potential pitfalls and recognize rare presentations. Each case sets oout one page of text, then one of treatment algorit
This book highlights various evolutionary algorithm techniques for various medical conditions and introduces medical applications of evolutionary computation for real-time diagnosis. Evolutionary Intelligence for Healthcare Applications presents how evolutionary intelligence can be used in smart healthcare systems involving big data analytics, mobile health, personalized medicine, and clinical trial data management. It focuses on emerging concepts and approaches and highlights various evolutionary algorithm techniques used for early disease diagnosis, prediction, and prognosis for medical conditions. The book also presents ethical issues and challenges that can occur within the healthcare system. Researchers, healthcare professionals, data scientists, systems engineers, students, programmers, clinicians, and policymakers will find this book of interest.
Comprehensive, user-friendly, and up to date, Chestnut's Obstetric Anesthesia: Principles and Practice, 6th Edition, provides the authoritative clinical information you need to provide optimal care to your patients. This substantially revised edition keeps you current on everything from basic science to anesthesia techniques to complications, including coverage of new research that is paving the way for improved patient outcomes. An expert editorial team ensures that this edition remains a must-have resource for obstetric anesthesiologists and obstetricians, nurse anesthetists and anesthesiology assistants, and anesthesiology and obstetric residents and students. Presents the latest information on anesthesia techniques for labor and delivery and medical disorders that occur during pregnancy, emphasizing the treatment of the fetus and the mother as separate patients with distinct needs. Contains new chapters on shared decision-making in obstetric anesthesia and chronic pain during and after pregnancy. Features extensive revisions from cover to cover, including consolidated information on maternal infection and postoperative analgesia. Covers key topics such as neonatal assessment and resuscitation, pharmacology during pregnancy and lactation, use of nitrous oxide for labor analgesia, programmed intermittent epidural bolus (PIEB) technique, epidural analgesia-associated fever, the role of gastric ultrasonography to assess the risk of aspiration, sugammadex in obstetric anesthesia, the role of video laryngoscopy and new supraglottic airway devices, spinal dysraphism, and cardiac arrest in obstetric patients. Incorporates the latest guidelines on congenital heart disease and the management of sepsis, as well as difficult airway guidelines that are specific to obstetric anesthesia practice. Offers abundant figures, tables, and boxes that illustrate the step-by-step management of a full range of clinical scenarios.
This book analyses the role of the mobility factor in the spread of Russian rule in Eurasia in the formative period of the rise of the Russian Empire and offers an examination of the interaction of Russian authorities with their nomadic partners. Demonstrating that the mobility factor strongly shaped the system of protectorate that the Russian and Qing monarchs imposed on their nomadic counterparts, the book argues that it operated as a flexible institutional framework, which enabled all sides to derive maximum benefits from a given political situation. The author establishes that interactions of Russian authorities with their Kalmyk and Qazaq counterparts during the mid-16th to the mid-19th centuries were strongly informed by the power dynamics of the Inner Asian frontier. These dynamics were marked by Russia’s rivalry with Qing Chinese and Jungar leaders to exert its influence over frontier nomadic populations. This book shows that each of these parties began to adopt key elements of existing steppe political culture. It also suggests that the different norms of governance adopted by the Russian state continued to shape its elite politics well into the 1820s and beyond. The author proposes that, by combining key elements of this culture with new practices, Russian authorities proved capable of creating innovative forms of governance that ended up shaping the very nature of the colonial Russian state itself. An important contribution to the ongoing debates pertaining to the nature of the spread of Russian rule over the numerous populations of the vast Eurasian terrains, this book will be of interest to academics working on Russian history, Central Asian/Eurasian history and political and cultural history.
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