The Antibody Molecule reviews the literature leading to current knowledge of the structure of immunoglobulins. The book begins by outlining some of the basic structural characteristics of immunoglobulins without citing the references on which the information is based. Separate chapters follow covering the chemical nature of the active site of an antibody molecule and mechanisms of interaction with hapten; the general structural features and properties of the various classes of human immunoglobulin; and amino acid sequences of human and mouse L chains and of human and rabbit H chains. Subsequent chapters deal with the evolution of the immunoglobulin classes; special properties of mouse, guinea pig, rabbit, and horse immunoglobulins; idiotypic specificities of immunglobulins; and the genetic control of antibodies. This book is meant for immunologists who have not personally observed the development of this exciting period in the history of immunology. It will also provide useful supplemental reading for the serious student or investigator who wishes to become familiar with the nature of the antibody molecule, its genetic control, and mode of action.
Analyzing an eclectic history of film and related media, Split Screen Nation argues that popular visions of the American West and the American South must be thought in relation to one another if we are to fully understand the marks both have left on popular ways of imagining the U.S.
Wartime memories evoke both pain and happiness in this heart-warming novel from multi-million copy seller and Sunday Times bestselling author Susan Sallis. Readers of Rosamunde Pilcher, Maeve Binchy and Fiona Valpy will not be disappointed. 'Sallis's West Country novel has the feel of Mary Wesley and character insight that is all her own' -- Daily Mail 'The thing about Susan Sallis's books - once you pick them up, it's very hard to put them down!' -- ***** Reader review 'Brilliant' -- ***** Reader review 'Excellent read, very enjoyable' - -- ***** Reader review 'Wonderful' - -- ***** Reader review ******************************************************************** THE ONLY PROMISE WORTH MAKING IS THE ONE YOU KEEP... There were four of the Thorpe family in the Anderson shelter the night of the raid on Coventry. Mum and Dad, Florrie and little May.... Jack was missing. He was one of those who had not come back from Dunkirk. And May had to promise to keep a terrible secret, a promise which affected the lives of all the survivors, until May herself was the only one left. Seventy years later Daisy and Marcus, sixth formers in a Gloucestershire School, are given an A Level project on the bombing of Coventry in 1940. They go to talk to May, now living in sheltered accommodation nearby. A friendship is forged which bridges the gap between them. The two youngsters have their own problems, but as their lives unfold they become involved in the strange history of May's missing brother and of the promise, made all those years ago, which still has its repercussions today.
Shakespeare Studies is an international volume published every year in hard cover, containing essays and studies by critics and cultural historians from both hemispheres. It includes substantial reviews of significant books and essays dealing with the cultural history of early modern England, as well as the place of Shakespeare's productions - and those of his contemporaries - within it. Volume XXXII continues the second in a series of essays on Early Modern Drama around the World in which specialists in theatrical traditions from around the globe during the time of Shakespeare discuss the state of scholarly study in their respective areas. O'Hara reviews work relevant to the theater of early modern France. Volume XXXII also includes another in the journal's series of Forums, entitled The Future of Renaissance Manuscript Studies. Organized and introduced by Peter Beal, the Forum includes contributions by Margaret J. M. Ezell, Grace Ioppolo, Harold Love, and Steven W. May. Additionally, this volume contains seven full-length articles and twenty-two book reviews. Leeds Barroll is a Scholar in Residence at the Folger Shakespeare Library,
Called "a feminist classic" by Judith Shulevitz in the New York Times Book Review, this pathbreaking book of literary criticism is now reissued with a new introduction by Lisa Appignanesi that speaks to how The Madwoman in the Attic set the groundwork for subsequent generations of scholars writing about women writers, and why the book still feels fresh some four decades later. "Gilbert and Gubar have written a pivotal book, one of those after which we will never think the same again."--Carolyn G. Heilbrun, Washington Post Book World
An intimate, lively guide to the magic and mechanics of editing by a veteran editor and writer, this book explores the many-faceted and often misunderstood--or simply overlooked--art of editing.
Literacy research has focused increasingly on the social, cultural, and material remaking of human communication. Such research has generated new knowledge about the diverse and interconnected modes and media through which people can and do make meaning and opened up definitions of literacy to include image, gaze, gesture, print, speech, and music. And yet, despite all of the attention to multimodality, questions remain that are fundamental to why multimodal literacy might matter to people and their communities. How, for instance, might multimodal literacy be implicated in wellbeing? And what of the little-researched sonic in multimodal ensembles? For centuries singing, as a basic form of human communication and tool for teaching and learning, has been used to share knowledge and pass on understandings of the world from one generation to another. What, however, are the implications of singing and its effects on people’s prospects for learning and making meaning together? In this thought-provoking book, the authors explore notions of wellbeing and what is created when skipped generations are brought together through singing-infused multimodal, intergenerational curricula. They argue for the import of singing as a multimodal literacy practice and unite theoretical ideas, practical tools, and empirical research findings from a ground-breaking seven-year study of intergenerational singing in multimodal curricula. Educators and researchers alike will find in the pages of this interdisciplinary book responses to the question of why multimodal literacy might matter and a sample curriculum designed to foster the expansion of people’s literacy and identity options across the lifespan. /div
This book examines the afterlife of the lollard movement, demonstrating how it was shaped and used by evangelicals and seventeenth-century Protestants. It focuses on the work of John Foxe, whose influential Acts and Monuments (1563) reoriented the lollards from heretics and traitors to martyrs and model subjects, portraying them as Protestants’ ideological forebears. It is a scholarly mainstay that Foxe edited radical lollard views to bring them in line with a mainstream monarchical church. But this book offers a strong corrective to the argument, revealing that the subversive material present in Foxe’s text allowed seventeenth-century religious radicals to appropriate the lollards as historical validation of their own theological and political positions. The book argues that the same lollards who were used to strengthen the English church in the sixteenth century would play a role in its fragmentation in the seventeenth.
The threat of unstoppable plagues, such as AIDS and Ebola, is always with us. In Europe, the most devastating plagues were those from the Black Death pandemic in the 1300s to the Great Plague of London in 1665. For the last 100 years, it has been accepted that Yersinia pestis, the infective agent of bubonic plague, was responsible for these epidemics. This book combines modern concepts of epidemiology and molecular biology with computer-modelling. Applying these to the analysis of historical epidemics, the authors show that they were not, in fact, outbreaks of bubonic plague. Biology of Plagues offers a completely new interdisciplinary interpretation of the plagues of Europe and establishes them within a geographical, historical and demographic framework. This fascinating detective work will be of interest to readers in the social and biological sciences, and lessons learnt will underline the implications of historical plagues for modern-day epidemiology.
Chronicles the period between the 4th and 12th centuries, when religion became the justification for political and military action, a time that included the development of Islam, the crowning of Charlemagne, and the rise of the T'ang Dynasty.
Ensure children with disabilities and special healthcare needs achieve their full potential. Noted authorities Susan Effgen, Allyssa LaForme Fiss and a team of scholars and clinical experts explore the role of the physical therapist in meeting the needs of children and their families in a culturally appropriate content using a family-centered, abilities-based model. From the major body systems to assistive technology and intervention support, you’ll develop the clinical knowledge you need to provide a child with the very best care from initial examination to graduation from your services.
Can you name ten actors who played women or ten actresses who played prostitutes in the movies? What about anyone who gained weight or got into shape for a movie role? And, there are those who fell in love on a movie set, performed together, and were paid big bucks for a divorce. The answers are in this book, although you might have a preference for someone I didn’t recognize. You might even learn something new about the movies or your favorite stars. Did you know that television’s Police Squad! ran for only six episodes, but it led to three movies. Do you remember when Paul Newman played himself on The Simpsons? The idea for the book was based on a childhood pastime similar to hopscotch, but without the hopping or standing on one leg. This book is sure to bring hours of entertainment. There are over 1000 entries, organized into ten chapters with ten sections each. Sit down, keep reading, and enjoy!
Endorsed by City and Guilds for use with The Certificate for IT Users Level 1 (part of the City & Guilds e-Quals suite). Practice assignments at the end of each unit are based on City & Guilds specifications.
Elizabeth Taylor was one of the major film stars of the twentieth century, embodying all the glamour and allure of Hollywood stardom. Yet her achievements as an actress have often been overshadowed by her beauty and tumultuous life off-screen. To redress this imbalance, Susan Smith offers an illuminating study of Elizabeth Taylor's work in film, exploring her fascinating trajectory from child to adult star. Smith reveals the influence that Taylor's early work exerted over her later career and the ways in which her on-screen identity is profoundly rooted in her association with animals and nature. Smith carefully unpicks what made Taylor such a distinctive and dynamic on-screen performer – from the expressive use she made of her eyes to the dramatic significance of her voice – and considers the importance of certain professional collaborations that Taylor forged during her career, most notably her acting partnership with Montgomery Clift.
In the stifling summer of 1826, the death of a young man in Hyde Park uncovers a web of blackmail and corruption so far-reaching that even the redoubtable Constable Sam Plank is shocked. A Quaker charity hides a terrible secret, a dangerous enmity is growing between London’s hackney carriage drivers and its watermen, and fraternal loyalty is tested to its limits. Susan Grossey’s third Sam Plank novel plunges the magistrates’ constable, his determined wife Martha and his protégé William Wilson into a dark and desperate world.
[The book] combines in one book the sixth edition of [the authors'] basic writing text Grassroots and 19 high interest reading selections ... [The book] is designed for students who have not yet mastered the basic writing skills so necessary for success in college and in many careers ... Each selection is accompanied by a headnote, vocabulary glosses, comprehension questions and writing assignments ... The range of materials and flexible format of [the book] makes this worktext adaptable to almost any teaching/learning situation: classroom, laboratory and self-teaching.-Pref.
Debrett's Peerage & Baronetage is the only up-to-date printed reference guide to the United Kingdom's titled families: the hereditary peers, life peers and peeresses, and baronets, and their descendants who form the fascinating tapestry of the peerage. This is the first ebook edition of Debrett's Peerage &Baronetage, and it also contains information relating to:The Royal FamilyCoats of ArmsPrincipal British Commonwealth OrdersCourtesy titlesForms of addressExtinct, dormant, abeyant and disclaimed titles.Special features for this anniversary edition include:The Roll of Honour, 1920: a list of the 3,150 people whose names appeared in the volume who were killed in action or died as a result of injuries sustained during the First World War.A number of specially commissioned articles, including an account of John Debrett's life and the early history of Debrett's Peerage and Baronetage, a history of the royal dukedoms, and an in-depth feature exploring the implications of modern legislation and mores on the ancient traditions of succession.
This represents the first study devoted to the life and after-life of St John of Beverley. John was bishop of Hexham and then York, after which he retired to his own monastery in Beverley and was buried there in 721. His cult was quickly established and spread to attract pilgrims from all over the British Isles, and even Europe. It was also established in Brittany by the tenth century, especially in the town of Saint-Jean-Brévelay, which is named after him. The great economic wealth of Beverley in the Middle Ages was largely due to it being a major ecclesiastical centre focused around John's relics. His reputation as a powerful saint was harnessed not only to protect Beverley and the surrounding areas and to give succour to pilgrims to his shrine, but also to further the ambitions of successive kings of England to the extent that Henry V raised him to the status of a patron saint of England following the battle of Agincourt, which was fought on the feast day of St John's translation. The hagiographic works on John extend over nearly six hundred years from that written by Bede c. 731, the Vita Sancti Johannis composed by a monk called Folcard c. 1066, then four separate collections of post-mortem miracle stories of the eleventh-thirteenth centuries, and a number of miracles recorded in the fourteenth and fifteenth centuries. This span is greater even than the hagiography relating to St Benedict, which had been believed to cover more years than any other collection in Europe. Dr Wilson uses these sources as a unique opportunity to examine the ways in which an Anglo-Saxon saint was promoted over a long period of time by different hagiographers, and how the saint was continually re-created in the image which the hagiographers or his community required, depending on their current needs and perceptions. The volume also includes the first English translations of the Life and the miracle stories.
In 1877, the American Humane Society was formed as the national organization for animal and child protection. Thirty years later, there were 354 anticruelty organizations chartered in the United States, nearly 200 of which were similarly invested in the welfare of both humans and animals. In The Rights of the Defenseless, Susan J. Pearson seeks to understand the institutional, cultural, legal, and political significance of the perceived bond between these two kinds of helpless creatures, and the attempts made to protect them. Unlike many of today’s humane organizations, those Pearson follows were delegated police powers to make arrests and bring cases of cruelty to animals and children before local magistrates. Those whom they prosecuted were subject to fines, jail time, and the removal of either animal or child from their possession. Pearson explores the limits of and motivation behind this power and argues that while these reformers claimed nothing more than sympathy with the helpless and a desire to protect their rights, they turned “cruelty” into a social problem, stretched government resources, and expanded the state through private associations. The first book to explore these dual organizations and their storied history, The Rights of the Defenseless will appeal broadly to reform-minded historians and social theorists alike.
Love and strife in the struggle for the crown that came to be known as the War of the Roses. Feeble-minded King Henry VI falls into a catatonic state and doesn't emerge for sixteen months. His queen, Margaret of Anjou, will do anything to protect her husband and young son. The great lords are fighting among themselves to become 'the power behind the throne'. These elements combine to lead the kingdom into civil strife: York against Lancaster. During the maelstrom of war, Anne of York looks for love outside her marriage to the cruel Duke of Exeter, who fights for the house of Lancaster. Her brother Edward is a carefree and charismatic youth, given more to the pursuit of women than the lust for a crown, but when his father and younger brother are killed in battle he throws off the follies of youth and emerges as an inspired leader and surprisingly able military man.
The British led the way in holidaymaking. This four-volume primary resource collection brings together a diverse range of texts on the various forms of transport used by tourists, the destinations they visited, the role of entertainments and accommodation and how these affected the way that tourism evolved over two centuries.Volume 1: Travel and Destinations Texts in this volume draw on accounts by early travellers, from short factual lists to longer subjective descriptions. Documents show how eagerly new forms of transport were adopted and how they gave rise to different leisure activities and new destinations. Methods of travel covered include: early road travel by horse or wagon, river travel via sail and steamships, railways, the safety bicycle, motorized transport (charabancs, coaches, buses, cars and bicycles) and finally, air travel.
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